Michael Lund Nielsen

Michael Lund Nielsen

Professor

ORCID: 0000-0002-0067-9039

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  1. Improving protein identification using complementary fragmentation techniques in Fourier transform mass spectrometry

    Nielsen, Michael Lund, Savitski, M. M. & Zubarev, R. A., 2005, In: Molecular and Cellular Proteomics. 4, 6, p. 835-845 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

    Nielsen, Michael Lund, Vermeulen, M., Bonaldi, T., Cox, J., Moroder, L. & Mann, M., 2008, In: Nature Methods. 5, 6, p. 459-460 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Tandem MALDI/El ionization for tandem Fourier transform ion cyclotron resonance mass spectrometry of polypeptides

    Nielsen, Michael Lund, Budnik, B. A., Haselmann, K. F. & Zubarev, R. A., 2003, In: International Journal of Mass Spectrometry. 226, 1, p. 181-187 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Peptide end sequencing by orthogonal MALDI tandem mass spectrometry

    Nielsen, Michael Lund, Bennett, K. L., Larsen, B., Moniatte, M. & Mann, M., 2002, In: Journal of Proteome Research. 1, 1, p. 63-71 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Specifying RNA-Binding Regions in Proteins by Peptide Cross-Linking and Affinity Purification

    Mullari, M., Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2017, In: Journal of Proteome Research. 16, 8, p. 2762-2772 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease

    Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

    Mooser, C., Symeonidou, I., Leimbacher, P., Ribeiro, A., Shorrocks, A. K., Jungmichel, S., Buch-Larsen, Sara Charlotte, Knechtle, K., Jasrotia, A., Zurbriggen, D., Jeanrenaud, A., Leikauf, C., Fink, D., Nielsen, Michael Lund, Blackford, A. N. & Stucki, M., 2020, In: Nature Communications. 11, 16 p., 123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

    Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast

    Mathiassen, S. G., Larsen, I. B., Poulsen, E. G., Madsen, C. T., Papaleo, E., Lindorff-Larsen, Kresten, Kragelund, Birthe Brandt, Nielsen, Michael Lund, Kriegenburg, F. & Hartmann-Petersen, Rasmus, 2015, In: The Journal of Biological Chemistry. 290, 34, p. 21141-21153 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4

    Martín Monreal, M. T., Stripp, Alexandra, Massarenti, Laura, Mondal, S., Šenolt, L., Ødum, Niels, Nielsen, Michael Lund, Thompson, P. R., Nielsen, Claus Henrik & Damgaard, D., 2021, In: Frontiers in Immunology. 12, 11 p., 716250.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Effectiveness of a coordinated and tailored return-to-work intervention for sickness absence beneficiaries with mental health problems

    Martin, M., Nielsen, Michael Lund, Madsen, I., Petersen, S., Lange, Theis & Rugulies, R., 2013, In: Journal of Occupational Rehabilitation. 23, 4, p. 621-30 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue

    Martello, R., Leutert, M., Jungmichel, S., Bilan, V., Buch-Larsen, Sara Charlotte, Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 1 Oct 2016, In: Nature Communications. 7, 13 p., 12917.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. ATP Enhances Neuronal Differentiation of PC12 Cells by Activating PKC alpha Interactions with Cytoskeletal Proteins

    Marin-Vicente, C., Guerrero-Valero, M., Nielsen, Michael Lund, Savitski, M. M., Gomez-Fernandez, J. C., Zubarev, R. A. & Corbalan-Garcia, S., 2011, In: Journal of Proteome Research. 10, 2, p. 529-540 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6

    Mantri, M., Webby, C. J., Loik, N. D., Hamed, R. B., McDonough, M. A., McCullagh, J. S. O., Schofield, C. J., Wolf, A., Nielsen, Michael Lund & Böttger, A., 1 Jan 2012, In: MedChemComm. 3, 1, p. 80-85 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

    Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    ADP-ribosyltransferases, an update on function and nomenclature

    Lüscher, B., Ahel, I., Altmeyer, M., Ashworth, A., Bai, P., Chang, P., Cohen, M., Corda, D., Dantzer, F., Daugherty, M. D., Dawson, T. M., Dawson, V. L., Deindl, S., Fehr, A. R., Feijs, K. L. H., Filippov, D. V., Gagné, J. P., Grimaldi, G., Guettler, S., Hoch, N. C. & 27 others, Hottiger, M. O., Korn, P., Kraus, W. L., Ladurner, A., Lehtiö, L., Leung, A. K. L., Lord, C. J., Mangerich, A., Matic, I., Matthews, J., Moldovan, G. L., Moss, J., Natoli, G., Nielsen, Michael Lund, Niepel, M., Nolte, F., Pascal, J., Paschal, B. M., Pawłowski, K., Poirier, G. G., Smith, S., Timinszky, G., Wang, Z. Q., Yélamos, J., Yu, X., Zaja, R. & Ziegler, M., 2022, In: FEBS Journal. 289, 23, p. 7399-7410

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism

    Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In: Nature Communications. 6, 12 p., 6807.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway

    Liu, Julio, Kühbacher, U., Larsen, N. B., Borgermann, N., Garvanska, Dimitriya Hristoforova, Hendriks, Ivo Alexander, Ackermann, Leena, Haahr, Peter Thorlund, Gallina, I., Guérillon, C., Branigan, E., Hay, R. T., Azuma, Y., Nielsen, Michael Lund, Duxin, Julien & Mailand, Niels, 2021, In: E M B O Journal. 40, 21 p., e107413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Identification of Protein Direct Interactome with Genetic Code Expansion and Search Engine OpenUaa

    Liu, C., Wu, T., Shu, X., Li, S., Wang, D. R., Wang, N., Zhou, R., Yang, H., Jiang, H., Hendriks, Ivo Alexander, Gong, P., Zhang, L., Nielsen, Michael Lund, Li, K., Wang, L. & Yang, B., 2021, In: Advanced Biology. 5, 3, 11 p., 2000308.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Immunoaffinity enrichments followed by mass spectrometric detection for studying global protein tyrosine phosphorylation

    Lind, S. B., Molin, M., Savitski, M. M., Emilsson, L., Astrom, J., Hedberg, L., Adams, C., Nielsen, Michael Lund, Engstrom, A., Elfineh, L., Andersson, E., Zubarev, R. A. & Pettersson, U., 2008, In: Journal of Proteome Research. 7, 7, p. 2897-2910 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. The RBCC gene RFP2 (leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD

    Lerner, M., Corcoran, M., Cepeda, D., Nielsen, Michael Lund, Zubarev, R., Ponten, F., Uhlen, M., Hober, S., Grander, D. & Sangfelt, O., 2007, In: Molecular Biology of the Cell. 18, 5, p. 1670-1682 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension

    Leeming, D. J., Karsdal, M. A., Byrjalsen, I., Bendtsen, Flemming, Trebicka, J., Nielsen, Michael Lund, Christiansen, C., Møller, Søren & Krag, A., 2013, In: Alimentary Pharmacology and Therapeutics. 38, 9, p. 1086-1096 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation

    Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Cell Reports. 24, 9, p. 2493-2505

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

    Buch-Larsen, Sara Charlotte, Sylvestersen, K. B., Mund, Andreas, Lyon, D., Mullari, M., Madsen, M. V., Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 30 Aug 2016, In: Science Signaling. 9, 443, 14 p., rs9.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography-Tandem Mass Spectrometry

    Buch-Larsen, Sara Charlotte, Leutert, M., Bilan, V., Martello, R., Jungmichel, S., Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 2017, Poly(ADP-Ribose) Polymerase. Tulin, A. V. (ed.). Humana Press, Vol. 1608. p. 149-162 14 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  26. Published

    The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage

    Larsen, D. H., Hari, F., Clapperton, J. A., Gwerder, M., Gutsche, K., Altmeyer, M., Jungmichel, S., Toledo Lazaro, L. I., Fink, D., Rask, M., Grøfte, M., Lukas, Claudia, Nielsen, Michael Lund, Smerdon, S. J., Lukas, Jiri & Stucki, M., Aug 2014, In: Nature Cell Biology. 16, 8, p. 792-803 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. PhosTShunter: A fast and reliable tool to detect phosphorylated peptides in liquid chromatography Fourier transform tandem mass spectrometry data sets

    Kocher, T., Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Journal of Proteome Research. 5, 3, p. 659-668 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. On studying protein phosphorylation patterns using bottom-up LC-MS/MS: the case of human alpha-casein

    Kjeldsen, F., Savitski, M. M., Nielsen, Michael Lund, Shi, L. & Zubarev, R. A., 2007, In: Analyst. 132, 8, p. 768-776 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)

    Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadrupole Orbitrap Mass Spectrometer

    Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2012, In: Journal of Proteome Research. p. 3487-3497 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication

    Kamalyukova, I. M., Young, C., Strømme, C. B., Ménard, Patrice, Jasencakova, Zuzana, Mejlvang, J., Ask, K., Ploug, Michael, Nielsen, Michael Lund, Jensen, O. N. & Groth, Anja, 2014, In: Nature Communications. 5, p. 3394

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry

    Jungmichel, S., Sylvestersen, K. B., Choudhary, Chunaram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In: Cell Reports. 6, 3, p. 578-91 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.

    Jungmichel, S., Clapperton, J. A., Janette, L., Hari, F. J., Spycher, C., Pavic, L., Li, J., Haire, L. F., Bonalli, M., Larsen, D. H., Lukas, C., Lukas, J., MacMillan, D., Nielsen, Michael Lund, Stucki, M. & Smerdon, S. J., 10 Jan 2012, In: Nucleic Acids Research. 40, 9, p. 4913-4928 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

    Jungmichel, S., Rosenthal, F., Altmeyer, M., Lukas, Jiri, Hottiger, M. O. & Nielsen, Michael Lund, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 272-285 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl

    Hou, W., Nemitz, S., Schopper, S., Nielsen, Michael Lund, Kessels, M. M. & Qualmann, B., 2018, In: Developmental Cell. 45, 2, p. 262-275.E8

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure

    Hertz, Emil Peter Thrane, Alonso de Vega, Ignacio, Kruse, Thomas, Wang, Y., Hendriks, Ivo Alexander, Bizard, A. H., Eugui-Anta, A., Hay, R. T., Nielsen, Michael Lund, Nilsson, Jakob, Hickson, Ian David & Mailand, Niels, 2023, In: Nature Structural and Molecular Biology. 30, p. 1303-1313

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    An advanced strategy for comprehensive profiling of ADP-ribosylation sites using mass spectrometry-based proteomics

    Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte & Nielsen, Michael Lund, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1010-1026

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Site-specific characterization of endogenous SUMOylation across species and organs

    Hendriks, Ivo Alexander, Lyon, D., Su, D., Skotte, Niels Henning, Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Nature Communications. 9, p. 1-17 2456.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The regulatory landscape of the human HPF1-and ARH3-dependent ADP-ribosylome

    Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte, Prokhorova, E., Elsborg, Jonas Damgaard, Stripp, Alexandra, Zhu, K., Ahel, D., Lukas, Claudia, Ahel, I. & Nielsen, Michael Lund, 2021, In: Nature Communications. 12, 1, 16 p., 5893.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation

    Hendriks, Ivo Alexander, Lyon, D., Young, C., Jensen, Lars Juhl, Vertegaal, A. C. O. & Nielsen, Michael Lund, Mar 2017, In: Nature Structural and Molecular Biology. 24, 3, p. 325-336 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    MaxQuant. Live Enables Enhanced Selectivity and Identification of Peptides Modified by Endogenous SUMO and Ubiquitin

    Hendriks, Ivo Alexander, Akimov, V., Blagoev, B. & Nielsen, Michael Lund, 2021, In: Journal of Proteome Research. 20, 4, p. 2042-2055 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Electronic excitation gives informative fragmentation of polypeptide cations and anions

    Haselmann, K. F., Budnik, B. A., Kjeldsen, F., Nielsen, Michael Lund, Olsen, Jesper Velgaard & Zubarev, R. A., 2002, In: European Journal of Mass Spectrometry. 8, 2, p. 117-121 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Advantages of external accumulation for electron capture dissociation in Fourier transform mass spectrometry

    Haselmann, K. F., Budnik, B. A., Olsen, Jesper Velgaard, Nielsen, Michael Lund, Reis, C. A., Clausen, H., Johnsen, A. H. & Zubarev, R. A., 2001, In: Analytical Chemistry. 73, 13, p. 2998-3005 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network

    Hammond, Colin, Bao, H., Hendriks, Ivo Alexander, Carraro, Massimo, García-Nieto, A., Liu, Y., Reveron-Gomez, Nazaret, Spanos, C., Chen, L., Rappsilber, J., Nielsen, Michael Lund, Patel, D. J., Huang, H. & Groth, Anja, 2021, In: Molecular Cell. 81, 12, p. 2533-2548

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites

    Guerillon, Claire Aline, Smedegaard, S., Hendriks, Ivo Alexander, Nielsen, Michael Lund & Mailand, Niels, 2020, In: Journal of Biological Chemistry. 295, p. 8350-8362

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Liquid chromatography at critical conditions: Comprehensive approach to sequence-dependent retention time prediction

    Gorshkov, A. V., Tarasova, I. A., Evreinov, V. V., Savitski, M. M., Nielsen, Michael Lund, Zubarev, R. A. & Gorshkov, M. V., 2006, In: Analytical Chemistry. 78, 22, p. 7770-7777 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The ubiquitin ligase RFWD3 is required for translesion DNA synthesis

    Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation

    Frogne, T., Sylvestersen, K. B., Kubicek, S., Nielsen, Michael Lund & Hecksher-Sørensen, J., 2012, In: P L o S One. 7, 4, p. e35233

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. De novo peptide sequencing and identification with precision mass spectrometry

    Frank, A. M., Savitski, M. M., Nielsen, Michael Lund, Zubarev, R. A. & Pevzner, P. A., 2007, In: Journal of Proteome Research. 6, 1, p. 114-123 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling

    Fontana, P., Buch-Larsen, Sara Charlotte, Suyari, O., Smith, R., Suskiewicz, M. J., Schützenhofer, K., Ariza, A., Rack, J. G. M., Nielsen, Michael Lund & Ahel, I., 2023, In: Nature Communications. 14, 1, 3200.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 13143239