Michael Lund Nielsen
Professor
Nielsen Group
Blegdamsvej 3B
2200 København N
A dual pressure linear ion trap orbitrap instrument with very high sequencing speed
Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparison of electron capture dissociation and collisionally activated dissociation of polycations of peptide nucleic acids
Olsen, Jesper Velgaard, Haselmann, K. F., Nielsen, Michael Lund, Budnik, B. A., Nielsen, P. E. & Zubarev, R. A., 2001, In: Rapid Communications in Mass Spectrometry. 15, 12, p. 969-74 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain
Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In: Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive profiling of proteome changes upon sequential deletion of deubiquitylating enzymes
Poulsen, J. W., Madsen, C. T., Young, C., Kelstrup, C. D., Grell, H. C., Henriksen, P., Jensen, Lars Juhl & Nielsen, Michael Lund, 2012, In: Journal of Proteomics. 75, 13, p. 3886-97 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using guanidine-hydrochloride for fast and efficient protein digestion and single-step affinity-purification mass spectrometry
Poulsen, J. W., Madsen, C. T., Young, C., Poulsen, F. M. & Nielsen, Michael Lund, 2013, In: Journal of Proteome Research. 12, 2, p. 1020-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
Prokhorova, E., Agnew, T., Wondisford, A. R., Tellier, M., Kaminski, N., Beijer, D., Holder, J., Groslambert, J., Suskiewicz, M. J., Zhu, K., Reber, J. M., Krassnig, S. C., Palazzo, L., Murphy, S., Nielsen, Michael Lund, Mangerich, A., Ahel, D., Baets, J., O'Sullivan, R. J. & Ahel, I., 2021, In: Molecular Cell. 81, 12, p. 2640-2655Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serine-linked PARP1 auto-modification controls PARP inhibitor response
Prokhorova, E., Zobel, F., Smith, R., Zentout, S., Gibbs-Seymour, I., Schützenhofer, K., Peters, A., Groslambert, J., Zorzini, V., Agnew, T., Brognard, J., Nielsen, Michael Lund, Ahel, D., Huet, S., Suskiewicz, M. J. & Ahel, I., 2021, In: Nature Communications. 12, 1, 12 p., 4055.Research output: Contribution to journal › Journal article › Research › peer-review
Experiences and perspectives of MALDI MS and MS/MS in proteomic research
Rappsilber, J., Moniatte, M., Nielsen, Michael Lund, Podtelejnikov, A. V. & Mann, M., 2003, In: International Journal of Mass Spectrometry. 226, 1, p. 223-237 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates
Stripp, Alexandra, Hendriks, Ivo Alexander, Elsborg, Jonas Damgaard, Buch-Larsen, Sara Charlotte, Nielsen, C. H., Terslev, L., Kirsch, Rebecca, Damgaard, D., Doncheva, Nadezhda Tsankova, Lennartsson, Caroline Linnea Elin, Rykær, M., Jensen, Lars Juhl, Christophorou, M. A. & Nielsen, Michael Lund, 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterizing citrullination by mass spectrometry-based proteomics
Stripp, Alexandra, Hendriks, Ivo Alexander & Nielsen, Michael Lund, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1890, 14 p., 20220237.Research output: Contribution to journal › Review › Research › peer-review
- Published
Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3
Richards, F., Llorca-Cardenosa, M. J., Langton, J., Buch-Larsen, Sara Charlotte, Shamkhi, N. F., Sharma, A. B., Nielsen, Michael Lund & Lakin, N. D., 2023, In: Nature Communications. 14, 1, 14 p., 4310.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets
Rodriguez, K. M., Buch-Larsen, Sara Charlotte, Kirby, I. T., Siordia, I. R., Hutin, D., Rasmussen, M., Grant, D. M., David, L. L., Matthews, J., Nielsen, Michael Lund & Cohen, M. S., 2021, In: eLife. 10, 35 p., e60480.Research output: Contribution to journal › Journal article › Research › peer-review
Electrospray ionization tandem mass spectrometry sequencing of novel skin peptides from Ranid frogs containing disulfide bridges
Samgina, T., Arternenko, K., Gorshkov, V., Lebedev, A., Nielsen, Michael Lund, Savitski, M. & Zubarev, R., 2007, In: European Journal of Mass Spectrometry. 13, 2, p. 155-163 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, Michael Lund, Kouzarides, T. & Castelo-Branco, G., 2019, In: Experimental Cell Research. 381, 1, p. 129-138 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Proteomics-grade de novo sequencing approach
Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F. & Zubarev, R. A., 2005, In: Journal of Proteome Research. 4, 6, p. 2348-2354 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Shifted-basis technique improves accuracy of peak position determination in Fourier transform mass spectrometry
Savitski, M. M., Ivonin, I. A., Nielsen, Michael Lund, Zubarev, R. A., Tsybin, Y. O. & Hakansson, P., 2004, In: Journal of The American Society for Mass Spectrometry. 15, 4, p. 457-461 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures
Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 935-948 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
New data base-independent, sequence tag-based scoring of peptide MS/MS data validates Mowse scores, recovers below threshold data, singles out modified peptides, and assesses the quality of MS/MS techniques
Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2005, In: Molecular and Cellular Proteomics. 4, 8, p. 1180-1188 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hydrogen rearrangement to and from radical z fragments in electron capture dissociation of peptides
Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Journal of The American Society for Mass Spectrometry. 18, 1, p. 113-120 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Backbone carbonyl group basicities are related to gas-phase fragmentation of peptides and protein folding
Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund, Garbuzynskiy, S. O., Galzitskaya, O. V., Surin, A. K. & Zubarev, R. A., 2007, In: Angewandte Chemie International Edition. 46, 9, p. 1481-1484 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Complementary sequence preferences of electron-capture dissociation and vibrational excitation in fragmentation of polypeptide polycations
Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Angewandte Chemie International Edition. 45, 32, p. 5301-5303 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Side-chain losses in electron capture dissociation to improve peptide identification
Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Analytical Chemistry. 79, 6, p. 2296-2302 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Relative specificities of water and ammonia losses from backbone fragments in collision-activated dissociation
Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Journal of Proteome Research. 6, 7, p. 2669-2673 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway
Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13143239
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Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
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Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism
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Published