Michael Lund Nielsen
Professor
Nielsen Group
Blegdamsvej 3B
2200 København N
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The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
Liquid chromatography at critical conditions: Comprehensive approach to sequence-dependent retention time prediction
Gorshkov, A. V., Tarasova, I. A., Evreinov, V. V., Savitski, M. M., Nielsen, Michael Lund, Zubarev, R. A. & Gorshkov, M. V., 2006, In: Analytical Chemistry. 78, 22, p. 7770-7777 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites
Guerillon, Claire Aline, Smedegaard, S., Hendriks, Ivo Alexander, Nielsen, Michael Lund & Mailand, Niels, 2020, In: Journal of Biological Chemistry. 295, p. 8350-8362Research output: Contribution to journal › Journal article › Research › peer-review
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DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network
Hammond, Colin, Bao, H., Hendriks, Ivo Alexander, Carraro, Massimo, García-Nieto, A., Liu, Y., Reveron-Gomez, Nazaret, Spanos, C., Chen, L., Rappsilber, J., Nielsen, Michael Lund, Patel, D. J., Huang, H. & Groth, Anja, 2021, In: Molecular Cell. 81, 12, p. 2533-2548Research output: Contribution to journal › Journal article › Research › peer-review
Advantages of external accumulation for electron capture dissociation in Fourier transform mass spectrometry
Haselmann, K. F., Budnik, B. A., Olsen, Jesper Velgaard, Nielsen, Michael Lund, Reis, C. A., Clausen, H., Johnsen, A. H. & Zubarev, R. A., 2001, In: Analytical Chemistry. 73, 13, p. 2998-3005 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Electronic excitation gives informative fragmentation of polypeptide cations and anions
Haselmann, K. F., Budnik, B. A., Kjeldsen, F., Nielsen, Michael Lund, Olsen, Jesper Velgaard & Zubarev, R. A., 2002, In: European Journal of Mass Spectrometry. 8, 2, p. 117-121 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation
Hendriks, Ivo Alexander, Lyon, D., Young, C., Jensen, Lars Juhl, Vertegaal, A. C. O. & Nielsen, Michael Lund, Mar 2017, In: Nature Structural and Molecular Biology. 24, 3, p. 325-336 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MaxQuant. Live Enables Enhanced Selectivity and Identification of Peptides Modified by Endogenous SUMO and Ubiquitin
Hendriks, Ivo Alexander, Akimov, V., Blagoev, B. & Nielsen, Michael Lund, 2021, In: Journal of Proteome Research. 20, 4, p. 2042-2055 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An advanced strategy for comprehensive profiling of ADP-ribosylation sites using mass spectrometry-based proteomics
Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte & Nielsen, Michael Lund, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1010-1026Research output: Contribution to journal › Journal article › Research › peer-review
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Site-specific characterization of endogenous SUMOylation across species and organs
Hendriks, Ivo Alexander, Lyon, D., Su, D., Skotte, Niels Henning, Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Nature Communications. 9, p. 1-17 2456.Research output: Contribution to journal › Journal article › Research › peer-review
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The regulatory landscape of the human HPF1-and ARH3-dependent ADP-ribosylome
Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte, Prokhorova, E., Elsborg, Jonas Damgaard, Stripp, Alexandra, Zhu, K., Ahel, D., Lukas, Claudia, Ahel, I. & Nielsen, Michael Lund, 2021, In: Nature Communications. 12, 1, 16 p., 5893.Research output: Contribution to journal › Journal article › Research › peer-review
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The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure
Hertz, Emil Peter Thrane, Alonso de Vega, Ignacio, Kruse, Thomas, Wang, Y., Hendriks, Ivo Alexander, Bizard, A. H., Eugui-Anta, A., Hay, R. T., Nielsen, Michael Lund, Nilsson, Jakob, Hickson, Ian David & Mailand, Niels, 2023, In: Nature Structural and Molecular Biology. 30, p. 1303-1313Research output: Contribution to journal › Journal article › Research › peer-review
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Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl
Hou, W., Nemitz, S., Schopper, S., Nielsen, Michael Lund, Kessels, M. M. & Qualmann, B., 2018, In: Developmental Cell. 45, 2, p. 262-275.E8Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses
Jungmichel, S., Rosenthal, F., Altmeyer, M., Lukas, Jiri, Hottiger, M. O. & Nielsen, Michael Lund, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 272-285 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry
Jungmichel, S., Sylvestersen, K. B., Choudhary, Chunaram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In: Cell Reports. 6, 3, p. 578-91 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Jungmichel, S., Clapperton, J. A., Janette, L., Hari, F. J., Spycher, C., Pavic, L., Li, J., Haire, L. F., Bonalli, M., Larsen, D. H., Lukas, C., Lukas, J., MacMillan, D., Nielsen, Michael Lund, Stucki, M. & Smerdon, S. J., 10 Jan 2012, In: Nucleic Acids Research. 40, 9, p. 4913-4928 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication
Kamalyukova, I. M., Young, C., Strømme, C. B., Ménard, Patrice, Jasencakova, Zuzana, Mejlvang, J., Ask, K., Ploug, Michael, Nielsen, Michael Lund, Jensen, O. N. & Groth, Anja, 2014, In: Nature Communications. 5, p. 3394Research output: Contribution to journal › Journal article › Research › peer-review
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Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)
Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadrupole Orbitrap Mass Spectrometer
Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2012, In: Journal of Proteome Research. p. 3487-3497 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
On studying protein phosphorylation patterns using bottom-up LC-MS/MS: the case of human alpha-casein
Kjeldsen, F., Savitski, M. M., Nielsen, Michael Lund, Shi, L. & Zubarev, R. A., 2007, In: Analyst. 132, 8, p. 768-776 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
PhosTShunter: A fast and reliable tool to detect phosphorylated peptides in liquid chromatography Fourier transform tandem mass spectrometry data sets
Kocher, T., Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Journal of Proteome Research. 5, 3, p. 659-668 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage
Larsen, D. H., Hari, F., Clapperton, J. A., Gwerder, M., Gutsche, K., Altmeyer, M., Jungmichel, S., Toledo Lazaro, L. I., Fink, D., Rask, M., Grøfte, M., Lukas, Claudia, Nielsen, Michael Lund, Smerdon, S. J., Lukas, Jiri & Stucki, M., Aug 2014, In: Nature Cell Biology. 16, 8, p. 792-803 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells
Buch-Larsen, Sara Charlotte, Sylvestersen, K. B., Mund, Andreas, Lyon, D., Mullari, M., Madsen, M. V., Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 30 Aug 2016, In: Science Signaling. 9, 443, 14 p., rs9.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography-Tandem Mass Spectrometry
Buch-Larsen, Sara Charlotte, Leutert, M., Bilan, V., Martello, R., Jungmichel, S., Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 2017, Poly(ADP-Ribose) Polymerase. Tulin, A. V. (ed.). Humana Press, Vol. 1608. p. 149-162 14 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation
Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Cell Reports. 24, 9, p. 2493-2505Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13143239
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Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
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Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism
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