Søren Brunak
Professor
Brunak Group
Blegdamsvej 3B
2200 København N
- 2019
- Published
Roadmap for a precision-medicine initiative in the Nordic region
Njølstad, P. R., Andreassen, O. A., Brunak, S., Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A., Mortensen, P. B., Palmgren, J. & 11 others, , 2019, In: Nature Genetics. 51, p. 924-930Research output: Contribution to journal › Comment/debate › Research
- Published
Combing the Hairball: Improving Visualization of miRNA-Target Interaction Networks
Russo, F., Hjaltelin, Jessica Xin, Romero Herrera, J. A. & Brunak, Søren, 2019, MicroRNA Target Identification: Methods and Protocols. Laganà, A. (ed.). Humana Press, p. 279-289 11 p. (Methods in Molecular Biology, Vol. 1970).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022
Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, S., Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M. & 21 others, , Nov 2019, In: Nature Reviews. Genetics. 20, 11, p. 702Research output: Contribution to journal › Comment/debate › Research
- Published
Leveraging European infrastructures to access 1 million human genomes by 2022
Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, S., Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M. & 21 others, , 2019, In: Nature Reviews. Genetics. 20, p. 693-701 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Population-wide analysis of differences in disease progression patterns in men and women
Westergaard, David, Moseley, P., Sørup, Freja Karuna Hemmingsen, Baldi, P. & Brunak, Søren, 2019, In: Nature Communications. 10, 1, 14 p., 666.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V. & 31 others, , 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Infrastruktur for klinik og forskning i Nationalt Genom Center
Ørntoft, T. F., Brunak, Søren, Jespergaard, C., Heickendorff, L., Grønkjær, K. & Løngreen, P., 1 Apr 2019, In: Ugeskrift for Laeger. 181, 7AResearch output: Contribution to journal › Journal article › Communication
- 2018
- Published
Analysis of Time-Series Gene Expression Data to Explore Mechanisms of Chemical-Induced Hepatic Steatosis Toxicity
Aguayo-Orozco, A., Bois, F. Y., Brunak, Søren & Taboureau, O., 2018, In: Frontiers in Genetics. 9, p. 1-15 396.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel Familial Cardiac Arrhythmia Syndrome with Widespread ST-Segment Depression
Bundgård, Henning, Jøns, C., Lodder, E. M., Izarzugaza, J. M. G., Romero Herrera, J. A., Pehrson, S., Tfelt-Hansen, Jacob, Ahlberg, G., Olesen, Morten Steen Salling, Holst, A. G., Wellens, H., de Villiers, C., Hastings, R., Stuart, G., Brunak, Søren, Wilde, A. A. M., Watkins, H. & Christensen, A. H., 2018, In: The New England Journal of Medicine. 379, 18, p. 1780-1781 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Familial co-occurrence of congenital heart defects follows distinct patterns
Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, V. E., Brunak, Søren & Larsen, Lars Allan, Mar 2018, In: European Heart Journal. 39, 12, p. 1015–1022Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study
Gudmundsdottir, V., Pedersen, H. K., Allebrandt, K. V., Brorsson, C. A., van Leeuwen, N., Banasik, K., Mahajan, A., Groves, C. J., van de Bunt, M., Dawed, A. Y., Fritsche, A., Staiger, H., Simonis-Bik, A. M. C., Deelen, J., Kramer, M. H. H., Dietrich, A., Hübschle, T., Willemsen, G., Häring, H-U., de Geus, E. J. C. & 8 others, , 2018, In: P L o S One. 13, 1, p. 1-19 e0189886.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Præcisionskardiologi
Haue, Amalie Dahl, Vissing, C. R., Tfelt-Hansen, Jacob, Brunak, Søren, Bundgård, Henning & Weeke, P. E., 1 Oct 2018, In: Ugeskrift for Laeger. 180, 20A, p. 1851-54Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in clinically recorded type 2 diabetes after colectomy
Jensen, A. B., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Jess, T., Brunak, Søren & Allin, K. H., 2018, In: eLife. 7, e37420.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of a gene panel for targeted sequencing of colorectal cancer samples
Jensen, K. H., Izarzugaza, J. M. G., Juncker, A. S., Hansen, R. B., Hansen, T. F., Timshel, P., Blondal, T., Jensen, T. S., Rygaard-Hjalsted, E., Mouritzen, P., Thorsen, M., Wernersson, R., Nielsen, H. B., Jakobsen, A., Brunak, Søren & Sørensen, F. B., 2018, In: OncoTarget. 9, 10, p. 9043-9060 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism
Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, Abigail, Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, Bjarne, Antignac, J., Le Bizec, B., Platel, C., Hay-Schmidt, Anders, Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, Karsten, Brunak, Søren, Kjær, Michael, Juul, Anders & Jégou, B., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. e715-e724 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios
Matey-Hernandez, M. L., Danish Pan Genome Consortium, D. P. G. C., Brunak, Søren, Izarzugaza, J. M. G., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Sun, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J., Eiberg, Hans Rudolf Lytchoff & Kristiansen, Karsten, 2018, In: BMC Bioinformatics. 19, p. 1-12 239.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study
Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, , 2018, In: Diabetologia. 61, 1, p. 117-129 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unexplored therapeutic opportunities in the human genome
Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, , 2018, In: Nature Reviews. Drug Discovery. 17, 5, p. 317-332 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links
Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comorbidity landscape of the Danish patient population affected by chromosomal abnormalities
Russo, F., Jørgensen, Isabella Friis, Westergaard, David, Jensen, A. B., Hjaltelin, Jessica Xin, Belling, K. & Brunak, Søren, 2018, In: European Journal of Human Genetics. 26, p. 697-698Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The Interplay of Non-coding RNAs and X Chromosome Inactivation in Human Disease
Russo, F., De Masi, F., Brunak, Søren & Belling, K. G., 2018, Systems Biology. Rajewsky, N., Jurga, S. & Barciszewski, J. (eds.). Springer, p. 229-238 (RNA Technologies).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
miRandola 2017: a curated knowledge base of non-invasive biomarkers
Russo, F., Di Bella, S., Vannini, F., Berti, G., Scoyni, F., Cook, H. V., Santos, A., Nigita, G., Bonnici, V., Laganà, A., Geraci, F., Pulvirenti, A., Giugno, R., De Masi, F., Belling, K., Jensen, Lars Juhl, Brunak, Søren, Pellegrini, M. & Ferro, A., 1 Jan 2018, In: Nucleic Acids Research. 46, D1, p. D354-D359 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accurate genotyping across variant classes and lengths using variant graphs
Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The governance structure for data access in the DIRECT consortium: an innovative medicines initiative (IMI) project
Teare, H. J. A., de Masi, F., Banasik, Karina, Barnett, A., Herrgard, S., Jablonka, B., Postma, J. W. M., McDonald, T. J., Forgie, I., Chmura, P. J., Rydzka, E. K., Gupta, R., Brunak, Søren, Pearson, E. & Kaye, J., 2018, In: Life Sciences, Society and Policy. 14, 1, p. 1-17 20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers
Tsafou, K., Katschnig, A. M., Radic-Sarikas, B., Mutz, C. N., Iljin, K., Schwentner, R., Kauer, M. O., Mühlbacher, K., Aryee, D. N. T., Westergaard, David, Haapa-Paananen, S., Fey, V., Superti-Furga, G., Toretsky, J., Brunak, Søren & Kovar, H., 2018, In: OncoTarget. 9, 57, p. 31018-31031 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12895347
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Identification of odorant-receptor interactions by global mapping of the human odorome
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
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A human gut microbial gene catalogue established by metagenomic sequencing
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