Søren Brunak

Søren Brunak

Professor

ORCID: 0000-0003-0316-5866

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  1. Published

    Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism

    Ghouse, J., Tragante, V., Ahlberg, G., Rand, S. A., Jespersen, J. B., Leinøe, E. B., Vissing, C. R., Trudsø, L., Jonsdottir, I., Banasik, K., Brunak, S., Ostrowski, S. R., Pedersen, O. B., Sørensen, E., Erikstrup, C., Bruun, M. T., Nielsen, K. R., Køber, L., Christensen, A. H., Iversen, K. & 16 others, Jones, D., Knowlton, K. U., Nadauld, L., Halldorsson, G. H., Ferkingstad, E., Olafsson, I., Gretarsdottir, S., Onundarson, P. T., Sulem, P., Thorsteinsdottir, U., Thorgeirsson, G., Gudbjartsson, D. F., Stefansson, K., Holm, H., Olesen, Morten Steen Salling & Bundgård, Henning, 2023, In: Nature Genetics. 55, p. 399-409 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Global priorities for large-scale biomarker-based prospective cohorts

    Collins, R., Balaconis, M. K., Brunak, Søren, Chen, Z., De Silva, M., Gaziano, J. M., Ginsburg, G. S., Jha, P., Kuri, P., Metspalu, A., Mulder, N. & Risch, N., 2022, In: Cell Genomics. 2, 6, 4 p., 100141.

    Research output: Contribution to journal › Comment/debate › Research

  3. Published

    Growth-rate regulated genes have profound impact on interpretation of transcriptome profiling in Saccharomyces cerevisiae

    Regenberg, Birgitte, Grotkjaer, T., Winther, Ole, Fausbøll, A., Akesson, M., Bro, C., Hansen, L. K., Brunak, Søren & Nielsen, Jens Bo, 2006, In: Genome Biology (Online Edition). 7, 11, p. R107

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population

    Nissen, J., Trabjerg, B., Pedersen, M. G., Banasik, K., Pedersen, O. B., Sørensen, E., Nielsen, K. R., Erikstrup, C., Petersen, M. S., Paarup, H. M., Bruun-Rasmussen, P., Westergaard, D., Hansen, T. F., Pedersen, C. B., Werge, T., Torrey, F., Hjalgrim, H., Mortensen, P. B., Yolken, R., Brunak, S. & 2 others, Ullum, H. & Burgdorf, K. S., Oct 2019, In: Psychoneuroendocrinology. 108, p. 150-154

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    High-Throughput Sequencing-Based Investigation of Viruses in Human Cancers by Multienrichment Approach

    Mollerup, S., Asplund, M., Friis-Nielsen, J., Kjartansdóttir, K. R., Fridholm, H., Hansen, T. A., Herrera, J. A. R., Barnes, C. J., Jensen, R. H., Richter, S. R., Nielsen, I. B., Pietroni, C., Alquezar-Planas, D. E., Rey-Iglesia, A., Olsen, P. V. S., Rajpert-De Meyts, E., Groth-Pedersen, L., von Buchwald, C., Jensen, D. H., Gniadecki, R. & 20 others, Høgdall, Estrid Vilma Solyom, Langhoff, J. L., Pete, I., Vereczkey, I., Baranyai, Z., Dybkaer, K., Johnsen, H. E., Steiniche, T., Hokland, P., Rosenberg, Jacob, Baandrup, U., Sicheritz-Pontén, Thomas, Willerslev, Eske, Brunak, Søren, Lund, O., Mourier, T., Vinner, Lasse, Izarzugaza, J. M. G., Nielsen, L. P. & Hansen, Anders Johannes, 15 Oct 2019, In: The Journal of Infectious Diseases. 220, 8, p. 1312-1324

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    High-throughput sequencing of circulating plasma microRNAs in newly diagnosed type 1 diabetes identifies four different patient clusters

    Sebastiani, G., Grieco, G. E., Fignani, D., Chmura, Piotr Jaroslaw, Brorsson, C. A., Bruggraber, S., Pugliese, A., Evans-Molina, C., Knip, M., Peakman, M., Schulte, A. M., Brunak, Søren, Dunger, D. B., Mathieu, C. & Dotta, F., 2020, In: Diabetologia. 63, Suppl. 1, p. S160 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  7. Published

    How Suitable Are Registry Data for Recurrence Risk Calculations? Validation of Diagnoses on 1,593 Families With Congenital Heart Disease

    Ellesøe, S. G., Jensen, A. B., Ängquist, Lars, Hjortdal, V. E., Larsen, Lars Allan & Brunak, Søren, Mar 2016, In: World journal for pediatric & congenital heart surgery. 7, 2, p. 169-77 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Human gut microbes impact host serum metabolome and insulin sensitivity

    Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., Vieira-Silva, S. & 14 others, Jørgensen, T., Holm, J. B., Trošt, K., Kristiansen, Karsten, Brix, Susanne, Raes, J., Wang, J., Hansen, Torben, Bork, P., Brunak, Søren, Oresic, M., Ehrlich, S. D., Pedersen, Oluf Borbye & MetaHIT Consortium, M. C., 2016, In: Nature. 535, 7612, p. 376-381 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis

    Berchtold, L. A., Størling, Z. M., Ortis, F., Lage, K., Bang-Berthelsen, C., Bergholdt, R., Hald, J., Brorsson, C. A., Eizirik, D. L., Pociot, Flemming, Brunak, Søren & Størling, Joachim, 2011, In: PNAS Early Edition. 108, 37, p. E681-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

    Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, Abigail, Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, Bjarne, Antignac, J., Le Bizec, B., Platel, C., Hay-Schmidt, Anders, Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, Karsten, Brunak, Søren, Kjær, Michael, Juul, Anders & Jégou, B., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. e715-e724 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Identification of Heterogenous Treatment Response Trajectories to anti-IL6 Receptor Treatment in Rheumatoid Arthritis

    Blair, J. P. M., Bager, C., Tang, M. H. E., Karsdal, M., Bay-Jensen, A. & Brunak, Søren, Oct 2019, In: Arthritis & Rheumatology. 71, S10, 3 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  12. Published

    Identification of T1D susceptibility genes within the MHC region by combining protein interaction networks and SNP genotyping data

    Brorsson, C., Hansen, N. T., Lage, K., Bergholdt, R., Brunak, Søren, Pociot, Flemming & Diabetes Genetics Consortium, D. G. C., Feb 2009, In: Diabetes, Obesity and Metabolism Online. 11, SUPPL. 1, p. 60-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer

    Börcsök, J., Sztupinszki, Z., Bekele, R., Gao, S. P., Diossy, M., Samant, A. S., Dillon, K. M., Tisza, V., Spisák, S., Rusz, O., Csabai, I., Pappot, H., Frazier, Z. J., Konieczkowski, D. J., Liu, D., Vasani, N., Rodrigues, J. A., Solit, D. B., Hoffman-Censits, J. H., Plimack, E. R. & 10 others, Rosenberg, J. E., Lazaro, J., Taplin, M., Iyer, G., Brunak, Søren, Lozsa, R., Van Allen, E. M., Szüts, D., Mouw, K. W. & Szallasi, Z., 2021, In: Clinical Cancer Research. 27, 7, p. 2011-2022 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Identification of biomarkers for glycaemic deterioration in type 2 diabetes

    Slieker, R. C., Donnelly, L. A., Akalestou, E., Lopez-Noriega, L., Melhem, R., Güneş, A., Abou Azar, F., Efanov, A., Georgiadou, E., Muniangi-Muhitu, H., Sheikh, M., Giordano, G. N., Åkerlund, M., Ahlqvist, E., Ali, A., Banasik, K., Brunak, S., Barovic, M., Bouland, G. A., Burdet, F. & 46 others, Canouil, M., Dragan, I., Elders, P. J. M., Fernandez, C., Festa, A., Fitipaldi, H., Froguel, P., Gudmundsdottir, V., Gudnason, V., Gerl, M. J., van der Heijden, A. A., Jennings, L. L., Hansen, M. K., Kim, M., Leclerc, I., Klose, C., Kuznetsov, D., Mansour Aly, D., Mehl, F., Marek, D., Melander, O., Niknejad, A., Ottosson, F., Pavo, I., Duffin, K., Syed, S. K., Shaw, J. L., Cabrera, O., Pullen, T. J., Simons, K., Solimena, M., Suvitaival, T., Wretlind, A., Rossing, Peter, Lyssenko, V., Legido Quigley, C., Groop, L., Thorens, B., Franks, P. W., Lim, G. E., Estall, J., Ibberson, M., Beulens, J. W. J., 't Hart, L. M., Pearson, E. R. & Rutter, G. A., 2023, In: Nature Communications. 14, 18 p., 2533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis

    Blair, J. P. M., Bay-Jensen, A. -., Tang, M. H., Frederiksen, P., Bager, C., Karsdal, M. & Brunak, Søren, 2020, In: Scientific Reports. 10, 1, 9 p., 13975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types

    Hjaltelin, Jessica Xin, Izarzugaza, J. M. G., Jensen, Lars Juhl, Russo, F., Westergaard, David & Brunak, Søren, 2019, In: npj Systems Biology and Applications. 5, 10 p., 27.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Identification of known and novel recurrent viral sequences in data from multiple patients and multiple cancers

    Friis-Nielsen, J., Kjartansdóttir, K. R., Mollerup, S., Asplund, M., Mourier, T., Jensen, R. H., Hansen, T. A., Rey de la Iglesia, A., Richter, S. R., Nielsen, I. B., Alquezar Planas, D. E., Olsen, P. V. S., Vinner, L., Fridholm, E. M. H., Nielsen, L. P., Willerslev, E., Sicheritz-Pontén, T., Lund, O., Hansen, A. J., Izarzugaza, J. M. G. & 1 others, Brunak, Søren, 2016, In: Viruses. 8, 2, 16 p., 53.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Identification of odorant-receptor interactions by global mapping of the human odorome

    Audouze, K. M. L., Tromelin, A., Le Bon, A. M., Belloir, C., Petersen, R. K., Kristiansen, Karsten, Brunak, Søren & Taboureau, O., 2014, In: PLOS ONE. 9, 4, p. e93037 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Identifying Sepsis Phenotypes

    Moseley, P. L. & Brunak, Søren, 2019, In: J A M A: The Journal of the American Medical Association. 322, 14, p. 1416-1417 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  20. Published

    Identifying patients at high risk of inappropriate drug dosing in periods with renal dysfunction

    Kaas-Hansen, Benjamin Skov, Rodriguez, C. L., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2021, medRxiv.

    Research output: Working paper › Preprint › Research

  21. Published

    Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers

    Tsafou, K., Katschnig, A. M., Radic-Sarikas, B., Mutz, C. N., Iljin, K., Schwentner, R., Kauer, M. O., Mühlbacher, K., Aryee, D. N. T., Westergaard, David, Haapa-Paananen, S., Fey, V., Superti-Furga, G., Toretsky, J., Brunak, Søren & Kovar, H., 2018, In: OncoTarget. 9, 57, p. 31018-31031 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity

    Fenton, T. M., Jørgensen, P. B., Niss, K., Rubin, S. J. S., Mörbe, U. M., Riis, Lene Buhl, Da Silva, C., Plumb, A., Vandamme, J., Jakobsen, H. L., Brunak, Søren, Habtezion, A., Nielsen, Ole Haagen, Johansson-Lindbom, B. & Agace, W. W., 2020, In: Immunity. 52, 3, p. 557-570, e1-e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization

    Pappalardo, F., Halling-Brown, M. D., Rapin, N., Zhang, P., Alemani, D., Emerson, A., Paci, P., Duroux, L. P., Pennisi, M., Palladini, A., Miotto, O., Churchill, D., Rossi, E., Shepherd, A. J., Moss, D. S., Castiglione, F., Bernaschi, M., Lefranc, M-P., Brunak, S., Motta, S. & 3 others, Lollini, P., Basford, K. E. & Brusic, V., 2009, In: Briefings in Bioinformatics. 10, 3, p. 330-40 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Impaired Vitamin D Signaling in T Cells From a Family With Hereditary Vitamin D Resistant Rickets

    Al-Jaberi, F. A. H., Kongsbak-Wismann, Martin, Aguayo-Orozco, A., Krogh, Nicolai, Buus, Terkild Brink, Lopez, D. V., Rode, A. K. O., Gravesen, Eva, Ølgaard, Klaus, Brunak, Søren, Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 11 p., 684015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Implementation and comparison of two text mining methods with a standard pharmacovigilance method for signal detection of medication errors

    Eskildsen, N. K., Eriksson, R., Christensen, S. B., Aghassipour, T. S., Bygsø, M. J., Brunak, Søren & Hansen, S. L., 2020, In: BMC Medical Informatics and Decision Making. 20, 1, 11 p., 94.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 12895347