Søren Brunak

Søren Brunak

Professor


  1. Published

    Dictionary construction and identification of possible adverse drug events in Danish clinical narrative text

    Eriksson, R., Jensen, P. B., Pletscher-Frankild, S., Jensen, Lars Juhl & Brunak, Søren, 23 May 2013, In: JAMIA - Journal of the American Medical Informatics Association. 20, 5, p. 947-953 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study

    Eriksen, R., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Prehn, C., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T. J. & 18 others, Kokkola, T., Rutter, F., Teare, H., Hansen, T. H., Fernandez, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, Oluf Borbye, Ruetten, H., Forgie, I., Bell, J. D., Pearson, E. R., Franks, P. W., Adamski, J., Holmes, E. & Frost, G., Aug 2020, In: EBioMedicine. 58, p. 102932

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium

    Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, T. H., Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, K. H., Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H. & 31 others, Rauh, S. P., Ridderstråle, M., Teare, H. J. A., Thomas, E. L., Tura, A., drb459, drb459, White, T., Adamski, J., Bell, J. D., Beulens, J. W., Brunak, Søren, Dermitzakis, E. T., Froguel, P., Frost, G., Gupta, R., Hansen, Torben, Hattersley, A., Jablonka, B., Kaye, J., Laakso, M., McDonald, T. J., Pedersen, Oluf Borbye, Schwenk, J. M., Pavo, I., Mari, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & IMI-DIRECT consortium, I. C., 2019, In: Diabetologia. 62, 9, p. 1601-1615

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia

    Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, Jablonka, B., Mari, A., McDonald, T., Dekker, J., Hansen, Torben, Hattersley, A., Laakso, M., Pedersen, Oluf Borbye, Koivisto, V., Ruetten, H., Walker, M., Pearson, E. & Franks, P., 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models: [with Author Correction]

    Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., Mahajan, A., Vinuela, A. & 31 others, Tajes, J. F., Sharma, S., Haid, M., Hong, M., Musholt, P. B., De Masi, F., Vogt, J., Pedersen, H. K., Gudmundsdottir, V., Jones, A., Kennedy, G., Bell, J., Thomas, E. L., Frost, G., Thomsen, Henrik S., Hansen, E., Hansen, T. H., drb459, drb459, Muilwijk, M., Blom, M. T., 't Hart, L. M., Pattou, F., Raverdy, V., Brage, S., Ridderstråle, M., Pedersen, Oluf Borbye, Hansen, Torben, Banasik, Karina, Rasmussen, Simon, Brunak, Søren & IMI-DIRECT consortium, I. C., 2023, In: Nature Biotechnology. 41, 3, p. 399–408 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Discrepancies in listed adverse drug reactions in pharmaceutical product information supplied by the regulatory authorities in Denmark and the USA

    Eriksson, R., Aagaard, L., Jensen, Lars Juhl, Borisova, L., Hørlück, D., Brunak, Søren & Hansen, E. H., 2014, In: Pharmacology Research & Perspectives. 2, 3, p. 1-10 e00038.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Discrete-time survival analysis in the critically ill: a deep learning approach using heterogeneous data

    Thorsen-Meyer, H., Placido, Davide, Kaas-Hansen, Benjamin Skov, Nielsen, A. P., Lange, Theis, Nielsen, A. B., Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Belling, K., Perner, Anders & Brunak, Søren, 2022, In: npj Digital Medicine. 5, 10 p., 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Disease Trajectories for Hidradenitis Suppurativa in the Danish Population

    Andersen, Rune Kjærsgaard, Jørgensen, Isabella Friis, Reguant, R., Jemec, Gregor & Brunak, Søren, 2020, In: JAMA Dermatology. 156, 7, p. 780-786

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients

    Siggaard, T., Reguant, R., Jørgensen, Isabella Friis, Haue, Amalie Dahl, Lademann, M., Aguayo-Orozco, A., Hjaltelin, Jessica Xin, Jensen, A. B., Banasik, Karina & Brunak, Søren, 2020, In: Nature Communications. 11, 1, 10 p., 4952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, Dore, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Dusko Ehrlich, S., Bork, P. & Pedersen, Oluf Borbye, 2015, In: Nature. 528, 7581, p. 262-266 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dissecting spatio-temporal protein networks driving human heart development and related disorders

    Hansen, K. L., Møllgård, K., Greenway, S., Wakimoto, H., Gorham, J. M., Workman, C. T., Bendsen, E., Hansen, N. T., Rigina, O., Roque, F. S., Wiese, C., Christoffels, V. M., Roberts, A. E., Smoot, L. B., Pu, W. T., Donahoe, P. K., Tommerup, N., Brunak, S., Seidman, C. E., Seidman, J. G. & 1 others, Larsen, Lars Allan, 2010, In: Molecular Systems Biology. 6, p. 381

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Dose-specific adverse drug reaction identification in electronic patient records: temporal data mining in an inpatient psychiatric population

    Eriksson, R., Werge, T., Jensen, Lars Juhl & Brunak, Søren, Apr 2014, In: Drug Safety. 37, 4, p. 237-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Drug dosage modifications in 24 million in-patient prescriptions covering eight years: A Danish population-wide study of polypharmacy

    Leal Rodríguez, C., Haue, Amalie Dahl, Mazzoni, G., Eriksson, R., Hernansanz Biel, J., Cantwell, Lisa, Westergaard, David, Belling, K. G. & Brunak, Søren, 2023, In: PLOS Digital Health. 2, 9, 27 p., e0000336.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Drug interactions in hospital prescriptions in Denmark: Prevalence and associations with adverse outcomes

    Rodríguez, C. L., Kaas-Hansen, Benjamin Skov, Eriksson, R., Biel, J. H., Belling, K. G., Andersen, Stig Ejdrup & Brunak, Søren, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 6, p. 632-642 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Dynamic and explainable machine learning prediction of mortality in patients in the intensive care unit: a retrospective study of high-frequency data in electronic patient records

    Thorsen-Meyer, H., Nielsen, A. B., Nielsen, A. P., Kaas-Hansen, Benjamin Skov, Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Dybdahl, L., Spangsege, L., Hulsen, P., Belling, K., Brunak, Søren & Perner, Anders, 2020, In: The Lancet Digital Health. 2, 4, p. e179–91 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Dynamic complex formation during the yeast cell cycle

    de Lichtenberg, U., Jensen, L. J., Brunak, Søren & Bork, P., 2005, In: Science (New York, N.Y.). 307, 5710, p. 724-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    ELIXIR-EXCELERATE: establishing Europe's data infrastructure for the life science research of the future

    ELIXIR-EXCELERATE Community, E. C., 2021, In: EMBO Journal. 40, 6, 9 p., e107409.

    Research output: Contribution to journalComment/debateResearch

  18. Published

    Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis

    Crèvecoeur, I., Gudmundsdottir, V., Vig, S., Marques Câmara Sodré, F., D'Hertog, W., Fierro, A. C., Van Lommel, L., Gysemans, C., Marchal, K., Waelkens, E., Schuit, F., Brunak, Søren, Overbergh, L. & Mathieu, C., Mar 2017, In: Diabetologia. 60, 3, p. 475-489 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Early divergent strains of Yersinia pestis in Eurasia 5,000 years ago

    Rasmussen, S., Allentoft, M. E., Nielsen, K., Orlando, L. A. A., Sikora, M., Sjögren, K-G., Pedersen, A. G., Schubert, M., Van Dam, A., Kapel, C. M. O., Nielsen, H. B., Brunak, S., Avetisyan, P., Epimakhov, A., Khalyapin, M. V., Gnuni, A., Kriiska, A., Lasak, I., Metspalu, M., Moiseyev, V. & 11 others, Gromov, A., Pokutta, D., Saag, L., Varul, L., Yepiskoposyan, L., Sicheritz-Ponten, T., Foley, R. A., Lahr, M. M., Nielsen, R., Kristiansen, K. & Willerslev, Eske, 2015, In: Cell. 163, 3, p. 571-582 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effects of active farnesoid X receptor on GLUTag enteroendocrine L cells

    Niss, K., Jakobsson, M. E., Westergaard, David, Belling, K. G., Olsen, Jesper Velgaard & Brunak, Søren, 2020, In: Molecular and Cellular Endocrinology. 517, 9 p., 110923.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor

    Dowsett, J., Ferkingstad, E., Rasmussen, L. J. H., Thørner, L. W., Magnússon, M. K., Sugden, K., Thorleifsson, G., Frigge, M., Burgdorf, K. S., Ostrowski, S. R., Sørensen, E., Erikstrup, C., Pedersen, O. B., Hansen, T. F., Banasik, K., Brunak, S., Tragante, V., Lund, S. H., Stefansdottir, L., Gunnarson, B. & 10 others, Poulton, R., Arseneault, L., Caspi, A., Moffitt, T. E., Gudbjartsson, D., Eugen-Olsen, J., Stefánsson, H., Stefánsson, K., Ullum, H. & DBDS Genomic Consortium, D. G. C., 2021, In: Communications Biology . 4, 1, p. 655

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Eliciting drug safety signals from patient records: a language-agnostic approach

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodriguez, C., Thorsen-Meyer, H., Gentile, S., Nielsen, A., Brunak, Søren, Jürgens, Gesche & Andersen, S., 2022, p. S15-S16. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  23. Published

    Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women

    Staunstrup, L. M., Bager, C. L., Frederiksen, P., Helge, Jørn Wulff, Brunak, Søren, Christiansen, C. & Karsdal, M., 2021, In: EBioMedicine. 68, 10 p., 103391.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, T., Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, J., Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In: Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Erratum to: Dose-Specific Adverse Drug Reaction Identification in Electronic Patient Records: Temporal Data Mining in an Inpatient Psychiatric Population

    Eriksson, R., Werge, T., Jensen, Lars Juhl & Brunak, Søren, May 2014, In: Drug Safety. 37, 5, p. 379

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 12895347