Søren Brunak
Professor
Brunak Group
Blegdamsvej 3B
2200 København N
- Published
Towards standardization guidelines for in silico approaches in personalized medicine
Brunak, Søren, Bjerre, C. C., Ó Cathaoir, Katharina, Golebiewski, M., Kirschner, M., Kockum, I., Moser, H. & Waltemath, D., 2020, In: Journal of integrative bioinformatics. 17, 2-3, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptional interactions suggest niche segregation among microorganisms in the human gut
Plichta, D. R., Juncker, A. S., Bertalan, M., Rettedal, E., Gautier, L., Varela, E., Manichanh, C., Fouqueray, C., Levenez, F., Nielsen, T., Doré, J., Machado, A. M. D., de Evgrafov, M. C. R., Hansen, T., Jørgensen, T., Bork, P., Guarner, F., Pedersen, O., Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium, Sommer, M. O. A. & 4 others, , 26 Aug 2016, In: Nature Microbiology. 1, p. 1-6 6 p., 16152.Research output: Contribution to journal › Letter › Research › peer-review
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Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells
Winge, S. B., Dalgaard, M. D., Belling, K. G., Jensen, J. M., Nielsen, J. E., Aksglaede, L., Schierup, M. H., Brunak, Søren, Skakkebæk, Niels Erik, Juul, Anders, Rajpert-De Meyts, E. & Almstrup, Kristian, 2018, In: Cell Death & Disease. 9, 6, 14 p., 586.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptome profiling of mice testes following low dose irradiation
Belling, K. C., Nielsen, H. B., Brunak, Søren, Tanaka, M., Dalgaard, M. D., Nielsen, J. E., Almstrup, Kristian & Leffers, H., 28 May 2013, In: Reproductive Biology and Endocrinology. 11, 1, 13 p., 50.Research output: Contribution to journal › Journal article › Research › peer-review
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Type I Interferons Promote Germinal Centers Through B Cell Intrinsic Signaling and Dendritic Cell Dependent Th1 and Tfh Cell Lineages
Dahlgren, M. W., Plumb, A. W., Niss, K., Lahl, K., Brunak, Søren & Johansson-Lindbom, B., 2022, In: Frontiers in Immunology. 13, 18 p., 932388.Research output: Contribution to journal › Journal article › Research › peer-review
Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology
Rojas, A. M., Santamaria, A., Malik, R., Jensen, T. S., Körner, R., Morilla, I., de Juan, D., Krallinger, M., Hansen, D. A., Hoffmann, R., Lees, J., Reid, A., Yeats, C., Wehner, A., Elowe, S., Clegg, A. B., Brunak, S., Nigg, E. A., Orengo, C., Valencia, A. & 1 others, , 2012, In: P L o S One. 7, 3, p. e31813Research output: Contribution to journal › Journal article › Research › peer-review
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Understanding inherent image features in CNN-based assessment of diabetic retinopathy
Reguant, R., Brunak, Søren & Saha, S., 2021, In: Scientific Reports. 11, 12 p., 9704.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unexplored therapeutic opportunities in the human genome
Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, , 2018, In: Nature Reviews. Drug Discovery. 17, 5, p. 317-332 16 p.Research output: Contribution to journal › Review › Research › peer-review
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Using Machine Learning to Identify Patients at High Risk of Inappropriate Drug Dosing in Periods with Renal Dysfunction
Kaas-Hansen, Benjamin Skov, Leal Rodríguez, C., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2022, In: Clinical Epidemiology. 14, p. 213-223 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Using electronic patient records to discover disease correlations and stratify patient cohorts
Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., Søeby, K., Bredkjær, S., Juul, Anders, Werge, Thomas, Jensen, Lars Juhl & Brunak, Søren, 2011, In: P L o S Computational Biology. 7, 8, p. e1002141 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination
Steinthorsdottir, V., Halldorsson, B. V., Jonsson, H., Palsson, G., Oddsson, A., Westergaard, D., Arnadottir, G. A., Stefansdottir, L., Banasik, K., Esplin, M. S., Hansen, T. F., Brunak, S., Nyegaard, M., Ostrowski, S. R., Pedersen, O. B. V., Erikstrup, C., Thorleifsson, G., Nadauld, L. D., Haraldsson, A., Steingrimsdottir, T. & 8 others, , 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology. 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants at the Interleukin 1 Gene Locus and Pericarditis
Thorolfsdottir, R. B., Jonsdottir, A. B., Sveinbjornsson, G., Aegisdottir, H. M., Oddsson, A., Stefansson, O. A., Halldorsson, G. H., Saevarsdottir, S., Thorleifsson, G., Stefansdottir, L., Pedersen, O. B., Sørensen, E., Ghouse, J., Raja, A. A., Zheng, C., Silajdzija, E., Rand, S. A., Erikstrup, C., Ullum, H., Mikkelsen, C. & 26 others, , 2024, In: JAMA Cardiology. 9, 2, p. 165-172 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Visualising disease trajectories from population-wide data
Hjaltelin, Jessica Xin, Currant, H., Jørgensen, Isabella Friis & Brunak, Søren, 2023, In: Frontiers in Bioinformatics. 3, 5 p., 1112113.Research output: Contribution to journal › Editorial › Research › peer-review
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Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study
Gudmundsdottir, V., Pedersen, H. K., Mazzoni, G., Allin, K. H., Artati, A., Beulens, J. W., Banasik, K., Brorsson, C., Cederberg, H., Chabanova, E., De Masi, F., Elders, P. J., Forgie, I., Giordano, G. N., Grallert, H., Gupta, R., Haid, M., Hansen, T., Hansen, T. H., Hattersley, A. T. & 36 others, , 2020, In: Genome Medicine. 12, 1, 17 p., 109.Research output: Contribution to journal › Journal article › Research › peer-review
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eTRANSAFE: data science to empower translational safety assessment
Sanz, F., Pognan, F., Steger-Hartmann, T., Díaz, C., Asakura, S., Amberg, A., Bécourt-Lhote, N., Blomberg, N., Bosc, N., Briggs, K., Bringezu, F., Brulle-Wohlhueter, C., Brunak, S., Bueters, R., Callegaro, G., Capella-Gutierrez, S., Centeno, E., Corvi, J., Cronin, M. T. D., Drew, P. & 41 others, , 2023, In: Nature Reviews Drug Discovery. 22, 8, p. 605-606 2 p.Research output: Contribution to journal › Comment/debate › Research
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hERG classification model based on a combination of support vector machine method and GRIND descriptors
Li, Q., Jørgensen, Flemming Steen, Oprea, T., Brunak, Søren & Taboureau, O., 2012, In: Molecular Pharmaceutics. 5, 1, p. 117-127 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miRandola 2017: a curated knowledge base of non-invasive biomarkers
Russo, F., Di Bella, S., Vannini, F., Berti, G., Scoyni, F., Cook, H. V., Santos, A., Nigita, G., Bonnici, V., Laganà, A., Geraci, F., Pulvirenti, A., Giugno, R., De Masi, F., Belling, K., Jensen, Lars Juhl, Brunak, Søren, Pellegrini, M. & Ferro, A., 1 Jan 2018, In: Nucleic Acids Research. 46, D1, p. D354-D359 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
sAOP: linking chemical stressors to adverse outcomes pathway networks
Aguayo-Orozco, A., Audouze, K., Siggaard, T., Barouki, R., Brunak, Søren & Taboureau, O., 2019, In: Bioinformatics. 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
wKinMut-2: Identification and Interpretation of Pathogenic Variants in Human Protein Kinases
Vazquez, M., Pons, T., Brunak, Søren, Valencia, A. & Izarzugaza, J. M. G., Jan 2016, In: Human Mutation. 37, 1, p. 36-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12895347
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Identification of odorant-receptor interactions by global mapping of the human odorome
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
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A human gut microbial gene catalogue established by metagenomic sequencing
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