Søren Brunak

Søren Brunak

Professor

ORCID: 0000-0003-0316-5866

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  1. Published

    Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors

    Pérez-Alós, L., Armenteros, J. J. A., Madsen, J. R., Hansen, C. B., Jarlhelt, I., Hamm, S. R., Heftdal, L. D., Pries-Heje, M. M., Møller, D. L., Fogh, K., Hasselbalch, R. B., Rosbjerg, A., Brunak, S., Sørensen, E., Larsen, M. A. H., Ostrowski, S. R., Frikke-Schmidt, R., Bayarri-Olmos, R., Hilsted, L. M., Iversen, K. K. & 3 others, Bundgård, Henning, Nielsen, Susanne Dam & Garred, Peter, 2022, In: Nature Communications. 13, 1, 11 p., 1614.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Mining electronic health records: towards better research applications and clinical care

    Jensen, P. B., Jensen, Lars Juhl & Brunak, Søren, 2012, In: Nature Reviews. Genetics. 13, 6, p. 395-405 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Migraine polygenic risk score associates with efficacy of migraine-specific drugs

    Kogelman, L. J. A., Esserlind, A-L., Christensen, A. F., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B., Erikstrup, C., Hjalgrim, H., Ullum, H., Olesen, J., Hansen, T. F., Gudbjartsson, D., Gastafsson, O., Stefansson, K., Stefansson, H., Porsteinsdottir, U., Andersen, S., Banasik, K., Brunak, S. & 73 others, Buil, A., Burgdorf, K., Gregor, J., Jennum, Poul, Nielsen, K. R., Nyegaard, M., Paarup, H. M., Pedersen, O. B., Sørensen, E., Werge, Thomas, Anttila, V., Artto, V., Belin, A. C., de Boer, I., Boomsma, D. I., Borte, S., Chasman, D. I., Cherkas, L., Cormand, B., Cuenca-Leon, E., Davey-Smith, G., Dichgans, M., van Duijn, C., Esko, T., Ferrari, M., Frants, R. R., Freilinger, T., Furlotte, N., Gormley, P., Griffiths, L., Hamalainen, E., Hiekkala, M., Ikram, M. A., Jarvelin, M., Kajanne, R., Kallela, M., Kaprio, J., Kaunisto, M., Kubisch, C., Kurki, M., Kurth, T., Launer, L., Lehtimaki, T., Lessel, D., Ligthart, L., Litterman, N., van den Maagdenberg, A., Macaya, A., Malik, R., Mangino, M., McMahon, G., Muller-Myhsok, B., Neale, B. M., Northover, C., Nyholt, D. R., Palotie, A., Palta, P., Pedersen, L., Pedersen, N., Posthuma, D., Pozo-Rosich, P., Pressman, A., Raitakari, O., Schurks, M., Sintas, C., Steinberg, S., Strachan, D., Terwindt, G., Vila-Pueyo, M., Wessman, M., Winsvold, B. S., Zhao, H. & Zwart, J., 2019, In: Neurology: Genetics. 5, 6, 12 p., e364.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    MicroRNAs, Regulatory Networks, and Comorbidities: Decoding Complex Systems

    Russo, F., Belling, K., Jensen, A. B., Scoyni, F., Brunak, Søren & Pellegrini, M., 2017, In: Methods in molecular biology (Clifton, N.J.). 1580, p. 281-295 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

    Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, Herder, C., Rathmann, W., Roden, M., Gieger, C., Kramer, M. H. H., van Heemst, D., Pedersen, H. K., Gudmundsdottir, V., Schulze, M. B., Pischon, T., de Geus, E. J. C., Boeing, H., Boomsma, D. I., Ziegler, A. G., Slagboom, P. E., Hummel, S., Beekman, M., Grallert, H., Brunak, Søren, McCarthy, M. I., Gupta, R., Pearson, E. R., Adamski, J. & 't Hart, L. M., 2018, In: Diabetologia. 61, 1, p. 117-129 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    MetaRanker 2.0: a web server for prioritization of genetic variation data

    Pers, T. H., Dworzynski, P., Thomas, C. E., Hansen, K. L. & Brunak, Søren, 1 Jul 2013, In: Nucleic Acids Research. 41, W1, p. W104-W108

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes

    Pers, T. H., Hansen, N. T., Hansen, K. L., Koefoed, P., Dworzynski, P., Miller, M. L., Flint, T. J., Mellerup, E., Dam, H., Andreassen, O. A., Djurovic, S., Melle, I., Børglum, A. D., Werge, T., Purcell, S., Ferreira, M. A., Kouskoumvekaki, I., Workman, C., Hansen, T., Mors, O. & 1 others, Brunak, Søren, 11 Apr 2011, In: Genetic Epidemiology. 35, 5, p. 318-332 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Mapping the human genetic architecture of COVID-19

    Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Andrews, S. J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E. C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M. A., Wendt, F. R., Savage, J., Sloofman, L. & 41 others, Butler-Laporte, G., Kim, H., Kanoni, S., Okada, Y., Byun, J., Han, Y., Uddin, M. J., Smith, G. D., Willer, C. J., Buxbaum, J. D., Karjalainen, J., Mehtonen, J., Folkersen, L., Moltke, Ida, Hinney, A., Wang, C., Ellinghaus, D., Brunak, Søren, Castro, P., Guindo Martínez, Marta, Lee, J. Y., Loos, Ruth, Zhao, J. H., Sun, Y. V., Wang, B., Parker, R., Garcia, S. M., Smith, O., Davis, C., COVID-19 Host Genetics Initiative, C. H. G. I., 23andMe COVID-19 Team, 2. C. T., Norwegian SARS-CoV-2 Study Grp, N. S. S. G., Humanitas COVID-19 Task Force, H. C. T. F., Humanitas Gavazzeni COVID-19 Task, H. G. C. T., FHoGID, F., RegCOVID, R., P-PredictUs, P., SeroCOVID, S., CRiPSI, C., Genes & Hlth Res Team, G. &. H. R. T. & UCLA Hlth ATLAS Data Mart Working, U. H. A. D. M. W., 2021, In: Nature. 600, p. 472-477

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

    Folkersen, L., Fauman, E., Sabater-Lleal, M., Strawbridge, R. J., Frånberg, M., Sennblad, B., Baldassarre, D., Veglia, F., Humphries, S. E., Rauramaa, R., de Faire, U., Smit, A. J., Giral, P., Kurl, S., Mannarino, E., Enroth, S., Johansson, Å., Enroth, S. B., Gustafsson, S., Lind, L. & 13 others, Lindgren, C. M., Morris, A. P., Giedraitis, V., Silveira, A., Franco-Cereceda, A., Tremoli, E., Gyllensten, U., Ingelsson, E., Brunak, Søren, Eriksson, P., Ziemek, D., Hamsten, A. & Mälarstig, A., Apr 2017, In: P L o S Genetics. 13, 4, 21 p., e1006706.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Many putative endocrine disruptors inhibit prostaglandin synthesis

    Kristensen, D. M., Skalkam, M. L., Audouze, K. M. L., Lesné, L., Desdoits-Lethimonier, C., Frederiksen, H., Brunak, Søren, Skakkebæk, Niels Erik, Jégou, B., Hansen, Jacob B., Junker, S. & Leffers, H., 1 Apr 2011, In: Environmental Health Perspectives. 119, 4, p. 534-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Machine Learning to Identify Patients at Risk of Inappropriate Dosing for Renal Risk Medications: A Critical Comment on Kaas-Hansen et al [Response to Letter]

    Kaas-Hansen, Benjamin Skov, Leal Rodríguez, C., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2022, In: Clinical Epidemiology. 14, p. 765-766 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  12. Published

    Long-term risk of cardiovascular and cerebrovascular disease after removal of the colonic microbiota by colectomy: a cohort study based on the Danish National Patient Register from 1996 to 2014

    Jensen, A. B., Ajslev, T. A., Brunak, Søren & Sørensen, Thorkild I.A., 15 Dec 2015, In: B M J Open. 5, 8 p., e008702.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Locating proteins in the cell using TargetP, SignalP and related tools

    Emanuelsson, O., Brunak, Søren, von Heijne, G. & Nielsen, Henrik, 2007, In: Nature Protocols (Online). 2, 4, p. 953-71 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes

    V Varga, Tibor, Ali, A., Herrera, J. A. R., Ahonen, L. L., Mattila, I. M., Al-Sari, N. H., Legido-Quigley, C., Skouby, Sven O., Brunak, Søren & Tornberg, Å. B., 2020, In: Scientific Reports. 10, 9 p., 2349.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Linking progression patterns in ischaemic heart disease to comorbidities and genetics by integrated analysis of electronic health records and population-wide registries

    Haue, Amalie Dahl, Holm, Peter Christoffer, Siggaard, T., Jørgensen, Isabella Friis, Simone, C., Eriksson, R., Orozco, A. A., Weeke, P. E., Christensen, A. H., Westergaard, David, Banasik, Karina, Køber, Lars Valeur, Ullum, H., Bundgård, Henning & Brunak, Søren, 2020, In: European Heart Journal. 41, p. 3496 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  16. Published

    Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

    Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, Brunak, Søren, 2019, In: eLife. 8, 19 p., e44941.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Linear motif atlas for phosphorylation-dependent signaling

    Miller, M. L., Jensen, L. J., Diella, F., Jørgensen, C., Tinti, M., Li, L., Hsiung, M., Parker, S. A., Bordeaux, J., Sicheritz-Ponten, T., Olhovsky, M., Pasculescu, A., Alexander, J., Knapp, S., Blom, N., Bork, P., Li, S., Cesareni, G., Pawson, T., Turk, B. E. & 3 others, Yaffe, M. B., Brunak, Søren & Linding, R., 2008, In: Science Signaling. 1, 35, p. ra2

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells

    Re, A., Workman, C. T., Waldron, L., Quattrone, A. & Brunak, Søren, 4 Aug 2014, In: Stem Cell Research. 13, 2, p. 316-328 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors

    Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, Møller, J. A., Boldsen, J. K., Burgdorf, Kristoffer Sølvsten, Kessing, Lars Vedel, Handgaard, L. J., Thørner, L. W., Didriksen, Maria, Nyegaard, Mette, Grarup, Niels, Ødum, Niels, Johansson, P. I., Jennum, Poul, Frikke-Schmidt, Ruth, Berger, S. S., Brunak, Søren, Jacobsen, Søren, Hansen, Thomas Folkmann, Lundquist, T. K., Hansen, Torben, Sørensen, Torben Lykke, Sigsgaard, T., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Ullum, H., Rostgaard, K., Sørensen, E., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye & Erikstrup, C., 2024, In: Communications Medicine. 4, 15 p., 50.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Leveraging European infrastructures to access 1 million human genomes by 2022

    Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, S., Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M. & 21 others, Korbel, J. O., Lappalainen, I., Leskosek, B., Matthijs, G., Mayrhofer, M. T., Metspalu, A., Navarro, A., Newhouse, S., Nyrönen, T., Page, A., Persson, B., Palotie, A., Parkinson, H., Rambla, J., Salgado, D., Steinfelder, E., Swertz, M. A., Valencia, A., Varma, S., Blomberg, N. & Scollen, S., 2019, In: Nature Reviews. Genetics. 20, p. 693-701 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Legacy data sharing to improve drug safety assessment: the eTOX project

    Sanz, F., Pognan, F., Steger-Hartmann, T., Díaz, C., Cases, M., Pastor, M., Marc, P., Wichard, J., Briggs, K., Watson, D. K., Kleinöder, T., Yang, C., Amberg, A., Beaumont, M., Brookes, A. J., Brunak, S., Cronin, M. T. D., Ecker, G. F., Escher, S., Greene, N. & 17 others, Guzmán, A., Hersey, A., Jacques, P., Lammens, L., Mestres, J., Muster, W., Northeved, H., Pinches, M., Saiz, J., Sajot, N., Valencia, A., van der Lei, J., Vermeulen, N. P. E., Vock, E., Wolber, G., Zamora, I. & eTOX, E., Dec 2017, In: Nature Reviews. Drug Discovery. 16, 12, p. 811-812 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders

    Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, K., Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, D., Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, S., Pedersen, C. B., Fuller Torrey, E., Werge, T., Bo Mortensen, P. & 2 others, Yolken, R. & Ullum, H., 2019, In: Brain, Behavior, and Immunity. 79, p. 152-158

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Lapatinib potentiates cytotoxicity of  YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter

    Radic-Sarikas, B., Halasz, M., Huber, K. V. M., Winter, G. E., Tsafou, K. P., Papamarkou, T., Brunak, Søren, Kolch, W. & Superti-Furga, G., 8 Jun 2017, In: Scientific Reports. 7, 1, p. 3091

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodríguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, In: Basic & clinical pharmacology & toxicology. 131, 4, p. 282-293 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodrìguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, Authorea, (Authorea Preprints).

    Research output: Working paper › Preprint › Research

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