Søren Brunak

Søren Brunak

Professor

ORCID: 0000-0003-0316-5866

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  1. Published

    Population-Based Characterization of Menstrual Migraine and Proposed Diagnostic Criteria

    Chalmer, M. A., Kogelman, L. J. A., Ullum, H., Sørensen, E., Didriksen, Maria, Mikkelsen, S., Dinh, K. M., Brodersen, T., Nielsen, K. R., Bruun, M. T., Banasik, Karina, Brunak, Søren, Erikstrup, C., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye, Olesen, Jes & Hansen, Thomas Folkmann, 2023, In: JAMA network open. 6, 5, 12 p., e2313235.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Population genomics of bronze age Eurasia

    Allentoft, M. E., Sikora, M., Sjogren, K-G., Rasmussen, S., Rasmussen, M., Stenderup, J., Damgaard, P. D. B., Schroeder, H., Ahlstrom, T., Vinner, L., Malaspinas, A. S., Margaryan, A., Higham, T., Chivall, D., Lynnerup, N., Harvig, L. L., Baron, J., Della Casa, P., Dabrowski, P., Duffy, P. R. & 46 others, Ebel, A. V., Epimakhov, A., Frei, K., Furmanek, M., Gralak, T., Gromov, A., Gronkiewicz, S., Grupe, G., Hajdu, T., Jarysz, R., Khartanovich, V., Khokhlov, A., Kiss, V., Kolar, J., Kriiska, A., Lasak, I., Longhi, C., McGlynn, G., Merkevicius, A., Merkyte, Inga, Metspalu, M., Mkrtchyan, R., Moiseyev, V., Paja, L., Palfi, G., Pokutta, D., Pospieszny, L., Price, T. D., Saag, L., Sablin, M., Shishlina, N., Smrcka, V., Soenov, V. I., Szeverenyi, V., Toth, G., Trifanova, S. V., Varul, L., Vicze, M., Yepiskoposyan, L., Zhitenev, V., Orlando, L. A. A., Sicheritz-Ponten, T., Brunak, Søren, Nielsen, Rasmus, Kristiansen, K. & Willerslev, Eske, 2015, In: Nature Genetics. 522, 7555, p. 167-172 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci

    Ghouse, J., Tragante, V., Muhammad, A., Ahlberg, G., Skov, M. W., Roden, D. M., Jonsdottir, I., Andreasen, L., Lundegaard, P. R., Trudsø, L. C., Banasik, K., Brunak, S., Ostrowski, S. R., Torp-Pedersen, C., Pedersen, O. V., Sørensen, E., Køber, L., Iversen, K., Thorsteinsdottir, U., Thorgeirsson, G. & 8 others, Ullum, H., Gudbjartsson, D. F., Mosley, J. D., Holm, H., Stefansson, K., Bundgård, Henning, Olesen, Morten Steen Salling & eMERGE consortium, E. C., 2022, In: European Heart Journal. 43, 45, p. 4707–4718

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Polychlorinated dibenzo-p-dioxins, furans, and biphenyls (PCDDs/PCDFs and PCBs) in breast milk and early childhood growth and IGF1

    Wohlfahrt-Veje, C., Audouze, K., Brunak, Søren, Antignac, J. P., le Bizec, B., Juul, Anders, Skakkebæk, Niels Erik & Main, Katharina Maria, 2014, In: Reproduction. 147, 4, p. 391-399 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Plasma YKL-40 is associated with prognosis in patients with metastatic pancreatic cancer receiving immune checkpoint inhibitors in combination with radiotherapy

    Johansen, A. Z., Novitski, Sif Ingibergsdóttir, Hjaltelin, Jessica Xin, Theile, S., Boisen, M. K., Brunak, Søren, Madsen, Daniel Hargbøl, Nielsen, Dorte Lisbet & Chen, I. M., 2023, In: Frontiers in Immunology. 14, 10 p., 1228907.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer

    Francavilla, C., Lupia, M., Tsafou, K., Villa, A., Kowalczyk, K., Rakownikow Jersie-Christensen, R., Bertalot, G., Confalonieri, S., Brunak, Søren, Jensen, Lars Juhl, Cavallaro, U. & Olsen, Jesper Velgaard, 28 Mar 2017, In: Cell Reports. 18, 13, p. 3242-3256 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Phenome-Wide Analysis of Short- and Long-Run Disease Incidence Following Recurrent Pregnancy Loss Using Data From a 39-Year Period

    Westergaard, D., Nielsen, A. P., Mortensen, Laust Hvas, Nielsen, Henriette Svarre & Brunak, Søren, 2020, In: Journal of the American Heart Association. 9, 8, 15 p., e015069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Pharos: Collating protein information to shed light on the druggable genome

    Nguyen, D-T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., Liu, G., Ma'ayan, A., Mandava, G., Mani, S., Mehta, S., Overington, J., Patel, J., Rouillard, A. D., Schürer, S., Sheils, T. & 10 others, Simeonov, A., Sklar, L. A., Southall, N., Ursu, O., Vidovic, D., Waller, A., Yang, J., Jadhav, A., Oprea, T. I. & Guha, R., Jan 2017, In: Nucleic Acids Research. 45, D1, p. D995–D1002

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Patterns of co-occurrence of congenital heart defects follows distinct patterns

    Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, Vibeke Elisabeth, Brunak, Søren & Larsen, Lars Allan, 2019, In: European Journal of Human Genetics. 26, p. 106 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  10. Published

    Patient stratification and identification of adverse event correlations in the space of 1190 drug related adverse events

    Roitmann, E., Eriksson, R. & Brunak, Søren, 11 Sep 2014, In: Frontiers in Physiology. 5, 14 p., 332.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Pathway and network analysis of more than 2500 whole cancer genomes

    Reyna, M. A., Haan, D., Paczkowska, M., Verbeke, L. P. C., Vazquez, M., Kahraman, A., Pulido-Tamayo, S., Barenboim, J., Wadi, L., Dhingra, P., Shrestha, R., Getz, G., Lawrence, M. S., Pedersen, J. S., Rubin, M. A., Wheeler, D. A., Brunak, S., Izarzugaza, J. M. G., Khurana, E., Marchal, K. & 32 others, von Mering, C., Sahinalp, S. C., Valencia, A., Abascal, F., Amin, S. B., Bader, G. D., Bandopadhayay, P., Beroukhim, R., Bertl, J., Boroevich, K. A., Busanovich, J., Campbell, P. J., Carlevaro-Fita, J., Chakravarty, D., Chan, C. W. Y., Chen, K., Choi, J. K., Deu-Pons, J., Diamanti, K., Feuerbach, L., Fink, J. L., Fonseca, N. A., Frigola, J., Gambacorti-Passerini, C., Garsed, D. W., Gerstein, M., Larsson, E., Nielsen, M. M., Sidiropoulos, N., Weischenfeldt, Joachim Lütken, PCAWG Drivers and Functional Interpretation Working Group, P. D. A. F. I. W. G. & PCAWG Consortium, P. C., 2020, In: Nature Communications. 11, 1, p. 1-17 729.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records

    Hjaltelin, Jessica Xin, Novitski, Sif Ingibergsdóttir, Jørgensen, Isabella Friis, Siggaard, T., Vulpius, S. A., Westergaard, D., Johansen, Julia Sidenius, Chen, I. M., Jensen, Lars Juhl & Brunak, Søren, 2023, In: eLife. 12, 15 p., e84919.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes

    Pedersen, H. K., Gudmundsdottir, V. & Brunak, Søren, 2017, In: Frontiers in Genetics. 8, 43.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Pan-cancer analysis of whole genomes

    ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, I. P. A. O. W. G. C., Weischenfeldt, Joachim Lütken, Sidiropoulos, N., Brunak, Søren & Rodriguez Gonzalez, Francisco G, 2020, In: Nature. 578, 7793, p. 82-93 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Optimizing drug selection from a prescription trajectory of one patient

    Aguayo-Orozco, A., Haue, Amalie Dahl, Jørgensen, Isabella Friis, Westergaard, D., Moseley, P. L., Mortensen, Laust Hvas & Brunak, Søren, 2021, In: npj Digital Medicine. 4, 1, 150.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    On the total number of genes and their length distribution in complete microbial genomes

    Skovgaard, M., Jensen, Lars Juhl, Brunak, Søren, Ussery, D. & Krogh, Anders, 2001, In: Trends in Genetics. 17, 8, p. 425-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. E-pub ahead of print

    Obesity variants in the GIPR gene do not associate with risk of fracture or bone mineral density

    Styrkarsdottir, U., Tragante, V., Stefansdottir, L., Thorleifsson, G., Oddsson, A., Sørensen, E., Erikstrup, C., Schwarz, Peter, Jørgensen, Henrik Løvendahl, Lauritzen, Jes Bruun, Brunak, Søren, Knowlton, K. U., Nadauld, L. D., Ullum, H., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye, Holm, H., Gudbjartsson, D. F., Sulem, P. & Stefansson, K., 2024, (E-pub ahead of print) In: Journal of Clinical Endocrinology and Metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    OCT4 and downstream factors are expressed in human somatic urogenital epithelia and in culture of epididymal spheres

    Kristensen, D. M., Nielsen, J. E., Kalisz, M., Dalgaard, M. D., Audouze, K., Larsen, M. E., Jacobsen, G. K., Horn, T., Brunak, S., Skakkebaek, N. E., Leffers, H., Kristensen, D. M., Nielsen, J. E., Kalisz, M., Dalgaard, M. D., Audouze, K. M. L., Larsen, M. E., Jacobsen, G. K., Horn, T., Brunak, S. & 2 others, Skakkebæk, Niels Erik & Leffers, H., 1 Nov 2010, In: Molecular Human Reproduction. 16, 11, p. 835-45 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Number of diagnoses based on number of publications

    Andersen, R. K., Bouazzi, D., Jørgensen, F., Brunak, Søren & Jemec, Gregor, 2020, In: Experimental Dermatology. 29, S1, p. 8-9 78.

    Research output: Contribution to journal › Conference abstract in journal › Research

  20. Published

    Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios

    Besenbacher, S., Liu, S., Gonzalez-Izarzugaza, J. M., Grove, J., Belling, K. G., Bork-Jensen, J., Huang, S., Als, T. D., Li, S., Yadav, R., Rubio García, A., Lescai, F., Demontis, D., Rao, J., Ye, W., Mailund, T., Møllegaard Friborg, R., Pedersen, C. N. S., Xu, R., Sun, J. & 27 others, Liu, H., Wang, O., Cheng, X., Flores, D., Rydza, E. K., Rapacki, K., Sørensen, J. D., Chmura, P. J., Westergaard, D., Dworzynski, P., Sørensen, Thorkild I.A., Lund, O., Hansen, Torben, Xu, X., Li, N., Bolund, L., Pedersen, Oluf Borbye, Eiberg, Hans Rudolf Lytchoff, Krogh, Anders, Børglum, A. D., Brunak, Søren, Kristiansen, Karsten, Schierup, M. H., Wang, J., Gupta, R., Villesen, P. & Rasmussen, Simon, 2015, In: Nature Communications. 6, 9 p., 5969.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Nomenclature for alleles of the human carboxylesterase 1 gene

    INDICES Consortium, I. C., 1 Jan 2017, In: Pharmacogenetics and Genomics. 27, 2, p. 78-80 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  22. Published

    Network biology concepts in complex disease comorbidities

    Hjaltelin, Jessica Xin, Thomas, Cecilia Engel & Brunak, Søren, Oct 2016, In: Nature Reviews. Genetics. 17, p. 615–629

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset

    Saevarsdottir, S., Stefansdottir, L., Sulem, P., Thorleifsson, G., Ferkingstad, E., Rutsdottir, G., Glintborg, B., Westerlind, H., Grondal, G., Loft, I. C., Sorensen, S. B., Lie, B. A., Brink, M., Ärlestig, L., Arnthorsson, A. O., Baecklund, E., Banasik, K., Bank, S., Bjorkman, L. I., Ellingsen, T. & 31 others, Erikstrup, C., Frei, O., Gjertsson, I., Gudbjartsson, D. F., Gudjonsson, S. A., Halldorsson, G. H., Hendricks, O., Hillert, J., Høgdall, Estrid Vilma Solyom, Jacobsen, Søren, Jensen, D. V., Jonsson, H., Kastbom, A., Kockum, I., Kristensen, S., Kristjansdottir, H., Larsen, M. H., Linauskas, A., Hauge, E., Loft, A. G., Ludviksson, B. R., Lund, S. H., Ostrowski, Sisse Rye, Sørensen, E., Sørensen, I. J., Brunak, Søren, Andersen, V., Hetland, Merete Lund, Askling, J., Pedersen, Ole Birger Vesterager & Members of the DBDS Genomic Consortium, M. O. T. D. G. C., 2022, In: Annals of the Rheumatic Diseases. 81, 8, p. 1085-1095

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Modules, networks and systems medicine for understanding disease and aiding diagnosis

    Gustafsson, M., Nestor, C. E., Zhang, H., Barabási, A., Baranzini, S., Brunak, Søren, Chung, K. F., Federoff, H. J., Gavin, A., Meehan, R. R., Picotti, P., Pujana, M. À., Rajewsky, N., Smith, K. G., Sterk, P. J., Villoslada, P. & Benson, M., Oct 2014, In: Genome Medicine. 6, 10, p. 82

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Modelling the human immune system by combining bioinformatics and systems biology approaches

    Rapin, N., Kesmir, C., Frankild, S., Nielsen, M., Lundegaard, C., Brunak, Søren & Lund, O., 2006, In: Journal of Biological Physics. 32, 3-4, p. 335-53 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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