Søren Brunak
Professor
Brunak Group
Blegdamsvej 3B
2200 København N
- 2024
- Published
Clonal hematopoiesis and COVID-19 hospitalization in Danish adults
Burgos Sequeros, C., Tulstrup, M., Bliddal, S., Sørensen, K. M., Nissen, I., Rezahosseini, O., Brooks, P. T., Feenstra, B., Gang, A. O., Geller, F., Hald, A., Harboe, Z. B., Helleberg, M., Jespersen, J. S., Lebech, A. M., Lindegaard, B., Mogensen, T. H., Møller, M. E. E., Nielsen, C. H., Niemann, C. U. & 13 others, , 2024, In: HemaSphere. 8, 3, 5 p., e58.Research output: Contribution to journal › Letter › Research › peer-review
- E-pub ahead of print
The association of cardiometabolic, diet and lifestyle parameters with plasma glucagon-like peptide-1: An IMI DIRECT study
Eriksen, R., White, M. C., Dawed, A. Y., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A. & 26 others, , 2024, (E-pub ahead of print) In: Journal of Clinical Endocrinology and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adopting Mechanistic Molecular Biology Approaches in Exposome Research for Causal Understanding
Foreman, A. L., Warth, B., Hessel, E. V. S., Price, E. J., Schymanski, E. L., Cantelli, G., Parkinson, H., Hecht, H., Klánová, J., Vlaanderen, J., Hilscherova, K., Vrijheid, M., Vineis, P., Araujo, R., Barouki, R., Vermeulen, R., Lanone, S., Brunak, Søren, Sebert, S. & Karjalainen, T., 2024, In: Environmental Science and Technology. 58, 17, p. 7256-7269 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive Reliability (FOREVER)—A cohort study in a Danish high street optician setting: Design and methodology
Freiberg, J., Rovelt, J., Gazzard, G., Cour, M. L., Kolko, M., Torp‐Pedersen, C., Benn, M., Brunak, S., Cour, M. L., Tolstrup, J., Toft‐Petersen, A. P., Burgdorf, K. S., Banasik, K., Chmura, P. J., Freiberg, J., Rovelt, J., Thornit, D. N., Foster, P., Gazzard, G., Crabb, D. P. & 4 others, , 2024, In: Acta Ophthalmologica. 102, 1, p. 80-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis
Ghouse, J., Sveinbjörnsson, G., Vujkovic, M., Seidelin, A-S., Gellert-Kristensen, H., Ahlberg, G., Tragante, V., Rand, S. A., Brancale, J., Vilarinho, S., Lundegaard, P. R., Sørensen, E., Erikstrup, C., Bruun, M. T., Jensen, B. A., Brunak, S., Banasik, K., Ullum, H., Verweij, N., Lotta, L. & 31 others, , 2024, In: Nature Genetics. 56, p. 827–837 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The robot butler: How and why should we study predictive algorithms and artificial intelligence (AI) in healthcare?
Gjødsbøl, Iben Mundbjerg, Ringgaard, A. K., Holm, Peter Christoffer, Brunak, Søren & Bundgård, Henning, 2024, In: Digital Health. 10, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stratification of Kidney Transplant Recipients Into Five Subgroups Based on Temporal Disease Trajectories
Jørgensen, Isabella Friis, Muse, V. P., Aguayo-Orozco, A., Brunak, Søren & Sørensen, Søren Schwartz, 2024, In: Transplantation Direct. 10, 2, 11 p., e1576.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors
Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, , 2024, In: Communications Medicine. 4, 15 p., 50.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol for EHR laboratory data preprocessing and seasonal adjustment using R and RStudio
Muse, V. P. & Brunak, Søren, 2024, In: STAR Protocols. 5, 1, 11 p., 102912.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Seasonally adjusted laboratory reference intervals to improve the performance of machine learning models for classification of cardiovascular diseases
Muse, V. P., Placido, Davide, Haue, Amalie Dahl & Brunak, Søren, 2024, In: BMC Medical Informatics and Decision Making. 24, 62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study of social trust in 33,882 Danish blood donors
Sequeros, C. B., Hansen, T. F., Westergaard, D., Louloudis, I., Kalamajski, S., Röder, T., Rohde, P. D., Schwinn, M., Clemmensen, L. H., Didriksen, M., Nyegaard, M., Hjalgrim, H., Nielsen, K. R., Bruun, M. T., Ostrowski, S. R., Erikstrup, C., Mikkelsen, S., Sørensen, E., Pedersen, O. B. V., Brunak, S. & 3 others, , 2024, In: Scientific Reports. 14, 12 p., 1402.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
Estonian Biobank, E. B. & DBDS Genomic Consortium, D. G. C., 2024, In: Communications Biology . 7, 1, 10 p., 504.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination
Steinthorsdottir, V., Halldorsson, B. V., Jonsson, H., Palsson, G., Oddsson, A., Westergaard, D., Arnadottir, G. A., Stefansdottir, L., Banasik, K., Esplin, M. S., Hansen, T. F., Brunak, S., Nyegaard, M., Ostrowski, S. R., Pedersen, O. B. V., Erikstrup, C., Thorleifsson, G., Nadauld, L. D., Haraldsson, A., Steingrimsdottir, T. & 8 others, , 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology. 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Obesity variants in the GIPR gene do not associate with risk of fracture or bone mineral density
Styrkarsdottir, U., Tragante, V., Stefansdottir, L., Thorleifsson, G., Oddsson, A., Sørensen, E., Erikstrup, C., Schwarz, Peter, Jørgensen, Henrik Løvendahl, Lauritzen, Jes Bruun, Brunak, Søren, Knowlton, K. U., Nadauld, L. D., Ullum, H., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye, Holm, H., Gudbjartsson, D. F., Sulem, P. & Stefansson, K., 2024, (E-pub ahead of print) In: Journal of Clinical Endocrinology and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants at the Interleukin 1 Gene Locus and Pericarditis
Thorolfsdottir, R. B., Jonsdottir, A. B., Sveinbjornsson, G., Aegisdottir, H. M., Oddsson, A., Stefansson, O. A., Halldorsson, G. H., Saevarsdottir, S., Thorleifsson, G., Stefansdottir, L., Pedersen, O. B., Sørensen, E., Ghouse, J., Raja, A. A., Zheng, C., Silajdzija, E., Rand, S. A., Erikstrup, C., Ullum, H., Mikkelsen, C. & 26 others, , 2024, In: JAMA Cardiology. 9, 2, p. 165-172 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Text mining of electronic health records can validate a register-based diagnosis of epilepsy and subgroup into focal and generalized epilepsy
Vulpius, S. A., Werge, S., Jørgensen, Isabella Friis, Siggaard, T., Hernansanz Biel, J., Knudsen, Gitte Moos, Brunak, Søren & Pinborg, Lars Hageman, 2024, In: Epilepsia. 64, 10, p. 2750-2760 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
Winther-Sørensen, Marie, Garcia, S. L., Bartholdy, Andreas, Ottenheijm, Maud Eline, Banasik, Karina, Brunak, Søren, Sorensen, Charlotte Mehlin, Gluud, Lise Lotte, Knop, Filip Krag, Holst, Jens Juul, Rosenkilde, Mette, Jensen, Majken Karoline & Albrechtsen, Nicolai Jacob Wewer, 6 May 2024, (E-pub ahead of print) In: Diabetologia.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Genetic variants associated with syncope implicate neural and autonomic processes
Aegisdottir, H. M., Thorolfsdottir, R. B., Sveinbjornsson, G., Stefansson, O. A., Gunnarsson, B., Tragante, V., Thorleifsson, G., Stefansdottir, L., Thorgeirsson, T. E., Ferkingstad, E., Sulem, P., Norddahl, G., Rutsdottir, G., Banasik, K., Christensen, A. H., Mikkelsen, C., Pedersen, O. B., Brunak, S., Bruun, M. T., Erikstrup, C. & 26 others, , 2023, In: European Heart Journal. 44, 12, p. 1070–1080 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models: [with Author Correction]
Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., Mahajan, A., Vinuela, A. & 31 others, , 2023, In: Nature Biotechnology. 41, 3, p. 399–408 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Increase in Specialist Treatment for Onychomycosis: An Unexplained Tendency. A Retrospective Study of Patients Treated for Onychomycosis in Danish Hospitals from 1994 to 2018
Andersen, P. L., Jørgensen, Isabella Friis, Saunte, Ditte Marie, Jemec, Gregor, Pedersen, Ole Birger Vesterager & Brunak, Søren, 2023, In: Journal of Fungi. 9, 1, 7 p., 33.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals
Banasik, K., Møller, P. L., Techlo, T. R., Holm, P. C., Walters, G. B., Ingason, A., Rosengren, A., Rohde, P. D., Kogelman, L. J. A., Westergaard, D., Siggaard, T., Chmura, P. J., Chalmer, M. A., Magnússon, Ó., Þórisson, G., Stefánsson, H., Guðbjartsson, D. F., Stefánsson, K., Olesen, J., Winther, S. & 5 others, , 2023, In: BMC Genomic Data. 24, 1, 4 p., 30.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
Beaumont, R. N., Flatley, C., Vaudel, M., Wu, X., Chen, J., Moen, G. H., Skotte, L., Helgeland, Ø., Solé-Navais, P., Banasik, K., Albiñana, C., Ronkainen, J., Fadista, J., Stinson, S. E., Trajanoska, K., Wang, C. A., Westergaard, D., Srinivasan, S., Sánchez-Soriano, C., Bilbao, J. R. & 68 others, , 2023, In: Nature Genetics. 55, 11, p. 1807-1819 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura
Bjornsdottir, G., Chalmer, M. A., Stefansdottir, L., Skuladottir, A. T., Einarsson, G., Andresdottir, M., Beyter, D., Ferkingstad, E., Gretarsdottir, S., Halldorsson, B. V., Halldorsson, G. H., Helgadottir, A., Helgason, H., Hjorleifsson Eldjarn, G., Jonasdottir, A., Jonasdottir, A., Jonsdottir, I., Knowlton, K. U., Nadauld, L. D., Lund, S. H. & 30 others, , 2023, In: Nature Genetics. 55, 11, p. 1843-1853Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits
Brown, A. A., Fernandez-Tajes, J. J., Hong, M. G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T. D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T., Hansen, T. H. & 134 others, , 2023, In: Nature Communications. 14, 17 p., 5062.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of ABO and Rhesus D blood groups with phenome-wide disease incidence: A 41-year retrospective cohort study of 482,914 patients
Bruun-Rasmussen, P., Dziegiel, Morten Hanefeld, Banasik, Karina, Johansson, Pär Ingemar & Brunak, Søren, 2023, In: eLife. 12, 17 p., e83116.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-Based Characterization of Menstrual Migraine and Proposed Diagnostic Criteria
Chalmer, M. A., Kogelman, L. J. A., Ullum, H., Sørensen, E., Didriksen, Maria, Mikkelsen, S., Dinh, K. M., Brodersen, T., Nielsen, K. R., Bruun, M. T., Banasik, Karina, Brunak, Søren, Erikstrup, C., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye, Olesen, Jes & Hansen, Thomas Folkmann, 2023, In: JAMA network open. 6, 5, 12 p., e2313235.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: The Danish Blood Donor Study
Erikstrup, C., Sørensen, E., Nielsen, K. R., Bruun, M. T., Petersen, M. S., Rostgaard, K., Thørner, L. W., Larsen, M., Mikkelsen, S., Dinh, K. M., Schwinn, M., Rigas, A. S., Didriksen, M., Dowsett, J., von Stemann, J. H., Brodersen, T., Paulsen, I. W., Hindhede, L., Sækmose, S. G., Kaspersen, K. A. & 10 others, , 2023, In: International Journal of Epidemiology. 52, 3, p. e162-e171 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism
Ghouse, J., Tragante, V., Ahlberg, G., Rand, S. A., Jespersen, J. B., Leinøe, E. B., Vissing, C. R., Trudsø, L., Jonsdottir, I., Banasik, K., Brunak, S., Ostrowski, S. R., Pedersen, O. B., Sørensen, E., Erikstrup, C., Bruun, M. T., Nielsen, K. R., Køber, L., Christensen, A. H., Iversen, K. & 16 others, , 2023, In: Nature Genetics. 55, p. 399-409 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association meta-analysis of knee and hip osteoarthritis uncovers genetic differences between patients treated with joint replacement and patients without joint replacement
Henkel, C., Styrkársdóttir, U., Thorleifsson, G., Stefánsdóttir, L., Björnsdóttir, G., Banasik, K., Brunak, S., Erikstrup, C., Dinh, K. M., Hansen, T. F., Nielsen, K. R., Bruun, M. T., Dowsett, J., Brodersen, T., Thorgeirsson, T. E., Gromov, K., Boesen, M. P., Ullum, H., Ostrowski, S. R., Pedersen, O. B. & 3 others, , 2023, In: Annals of the Rheumatic Diseases. 82, p. 384-392Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records
Hjaltelin, Jessica Xin, Novitski, Sif Ingibergsdóttir, Jørgensen, Isabella Friis, Siggaard, T., Vulpius, S. A., Westergaard, D., Johansen, Julia Sidenius, Chen, I. M., Jensen, Lars Juhl & Brunak, Søren, 2023, In: eLife. 12, 15 p., e84919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualising disease trajectories from population-wide data
Hjaltelin, Jessica Xin, Currant, H., Jørgensen, Isabella Friis & Brunak, Søren, 2023, In: Frontiers in Bioinformatics. 3, 5 p., 1112113.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Plasma YKL-40 is associated with prognosis in patients with metastatic pancreatic cancer receiving immune checkpoint inhibitors in combination with radiotherapy
Johansen, A. Z., Novitski, Sif Ingibergsdóttir, Hjaltelin, Jessica Xin, Theile, S., Boisen, M. K., Brunak, Søren, Madsen, Daniel Hargbøl, Nielsen, Dorte Lisbet & Chen, I. M., 2023, In: Frontiers in Immunology. 14, 10 p., 1228907.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Precision medicine in complex diseases - Molecular subgrouping for improved prediction and treatment stratification
Johansson, Å., Andreassen, O. A., Brunak, Søren, Franks, P. W., Hedman, H., Loos, Ruth, Meder, B., Melén, E., Wheelock, C. E. & Jacobsson, B., 2023, In: Journal of Internal Medicine. 294, 4, p. 378-396 19 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A second update on mapping the human genetic architecture of COVID-19
Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, , 2023, In: Nature. 621, 7977, p. E7-E26 23 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Drug dosage modifications in 24 million in-patient prescriptions covering eight years: A Danish population-wide study of polypharmacy
Leal Rodríguez, C., Haue, Amalie Dahl, Mazzoni, G., Eriksson, R., Hernansanz Biel, J., Cantwell, Lisa, Westergaard, D., Belling, K. G. & Brunak, Søren, 2023, In: PLOS Digital Health. 2, 9, 27 p., e0000336.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus
Lundgaard, Agnete Troen, Burdet, F., Siggaard, T., Westergaard, D., Vagiaki, D., Cantwell, Lisa, Röder, T., Vistisen, D., Sparsø, T., Giordano, G. N., Ibberson, M., Banasik, Karina & Brunak, Søren, 2023, In: PLOS Computational Biology. 19, 8, 13 p., e1011403.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic prediction of 33 blood group phenotypes using an existing genotype dataset
Moslemi, C., Sækmose, S. G., Larsen, R., Bay, J. T., Brodersen, T., Didriksen, M., Hjalgrim, H., Banasik, K., Nielsen, K. R., Bruun, M. T., Dowsett, J., Dinh, K. M., Mikkelsen, S., Mikkelsen, C., Hansen, T. F., Ullum, H., Erikstrup, C., Brunak, S., Krogfelt, K. A., Storry, J. R. & 3 others, , 2023, In: Transfusion. 63, 12, p. 2297-2310 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory
Moulder, R., Välikangas, T., Hirvonen, M. K., Suomi, T., Brorsson, C. A., Lietzén, N., Bruggraber, S. F. A., Overbergh, L., Dunger, D. B., Peakman, M., Chmura, Piotr Jaroslaw, Brunak, Søren, Schulte, A. M., Mathieu, C., Knip, M., Elo, L. L., Lahesmaa, R. & on behalf of the INNODIA consortium, O. B. O. T. I. C., 2023, In: Diabetologia. 66, p. 1983-1996Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-wide analysis of hospital laboratory tests to assess seasonal variation and temporal reference interval modification
Muse, V. P., Aguayo-Orozco, A., Balaganeshan, Sedrah Butt & Brunak, Søren, 2023, In: Patterns. 4, 8, 14 p., 100778.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An atlas of genetic determinants of forearm fracture
Nethander, M., Movérare-Skrtic, S., Kämpe, A., Coward, E., Reimann, E., Grahnemo, L., Borbély, É., Helyes, Z., Funck-Brentano, T., Cohen-Solal, M., Tuukkanen, J., Koskela, A., Wu, J., Li, L., Lu, T., Gabrielsen, M. E., Mägi, R., Hoff, M., Lerner, U. H., Henning, P. & 15 others, , 2023, In: Nature Genetics. 55, 11, p. 1820-1830 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Oddsson, A., Sulem, P., Sveinbjornsson, G., Arnadottir, G. A., Steinthorsdottir, V., Halldorsson, G. H., Atlason, B. A., Oskarsson, G. R., Helgason, H., Nielsen, H. S., Westergaard, D., Karjalainen, J. M., Katrinardottir, H., Fridriksdottir, R., Jensson, B. O., Tragante, V., Ferkingstad, E., Jonsson, H., Gudjonsson, S. A., Beyter, D. & 31 others, , 2023, In: Nature Communications. 14, 15 p., 3453.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A unidirectional mapping of ICD-8 to ICD-10 codes, for harmonized longitudinal analysis of diseases
Pedersen, M. K., Eriksson, R., Reguant, R., Collin, C., Pedersen, H. K., Sørup, Freja Karuna Hemmingsen, Simon, C., Birch, A. M., Larsen, Michael, Nielsen, A. P., Belling, K. & Brunak, Søren, 2023, In: European Journal of Epidemiology. 38, p. 1043–1052 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories
Placido, D., Yuan, B., Hjaltelin, J. X., Zheng, C., Haue, A. D., Chmura, P. J., Yuan, C., Kim, J., Umeton, R., Antell, G., Chowdhury, A., Franz, A., Brais, L., Andrews, E., Marks, D. S., Regev, A., Ayandeh, S., Brophy, M. T., Do, N. V., Kraft, P. & 5 others, , 2023, In: Nature Medicine. 29, p. 1113-1122Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a dynamic prediction model for unplanned ICU admission and mortality in hospitalized patients
Placido, Davide, Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, Reguant, R. & Brunak, Søren, 2023, In: PLOS Digital Health. 2, 6, 18 p., e0000116.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The small and large intestine contain related mesenchymal subsets that derive from embryonic Gli1+ precursors
Pærregaard, S. I., Wulff, L., Schussek, S., Niss, K., Mörbe, U., Jendholm, J., Wendland, K., Andrusaite, A. T., Brulois, K. F., Nibbs, R. J. B., Sitnik, K., Mowat, A. M. I., Butcher, E. C., Brunak, Søren & Agace, W. W., 2023, In: Nature Communications. 14, 1, 2307.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
Roychowdhury, T., Klarin, D., Levin, M. G., Spin, J. M., Rhee, Y. H., Deng, A., Headley, C. A., Tsao, N. L., Gellatly, C., Zuber, V., Shen, F., Hornsby, W. E., Laursen, I. H., Verma, S. S., Locke, A. E., Einarsson, G., Thorleifsson, G., Graham, S. E., Dikilitas, O., Pattee, J. W. & 74 others, , 2023, In: Nature Genetics. 55, p. 1831–1842 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
eTRANSAFE: data science to empower translational safety assessment
Sanz, F., Pognan, F., Steger-Hartmann, T., Díaz, C., Asakura, S., Amberg, A., Bécourt-Lhote, N., Blomberg, N., Bosc, N., Briggs, K., Bringezu, F., Brulle-Wohlhueter, C., Brunak, S., Bueters, R., Callegaro, G., Capella-Gutierrez, S., Centeno, E., Corvi, J., Cronin, M. T. D., Drew, P. & 41 others, , 2023, In: Nature Reviews Drug Discovery. 22, 8, p. 605-606 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Deep integrative models for large-scale human genomics
Sigurdsson, Arnór Ingi, Louloudis, Ioannis, Banasik, Karina, Westergaard, D., Winther, Ole, Lund, O., Ostrowski, Sisse Rye, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nyegaard, Mette, Brunak, Søren, Vilhjálmsson, B. & Rasmussen, Simon, 2023, In: Nucleic Acids Symposium Series. 51, 12, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of biomarkers for glycaemic deterioration in type 2 diabetes
Slieker, R. C., Donnelly, L. A., Akalestou, E., Lopez-Noriega, L., Melhem, R., Güneş, A., Abou Azar, F., Efanov, A., Georgiadou, E., Muniangi-Muhitu, H., Sheikh, M., Giordano, G. N., Åkerlund, M., Ahlqvist, E., Ali, A., Banasik, K., Brunak, S., Barovic, M., Bouland, G. A., Burdet, F. & 46 others, , 2023, In: Nature Communications. 14, 18 p., 2533.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complex effects of sequence variants on lipid levels and coronary artery disease
Snaebjarnarson, A. S., Helgadottir, A., Arnadottir, G. A., Ivarsdottir, E. V., Thorleifsson, G., Ferkingstad, E., Einarsson, G., Sveinbjornsson, G., Thorgeirsson, T. E., Ulfarsson, M. O., Halldorsson, B. V., Olafsson, I., Erikstrup, C., Pedersen, O. B., Nyegaard, M., Bruun, M. T., Ullum, H., Brunak, S., Iversen, K. K., Christensen, A. H. & 14 others, , 2023, In: Cell. 186, 19, p. 4085-4099.e15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression signature predicts rate of type 1 diabetes progression
Suomi, T., Starskaia, I., Kalim, U. U., Rasool, O., Jaakkola, M. K., Grönroos, T., Välikangas, T., Brorsson, C., Mazzoni, G., Bruggraber, S., Overbergh, L., Dunger, D., Peakman, M., Chmura, P., Brunak, S., Schulte, A. M., Mathieu, C., Knip, M., Lahesmaa, R., Elo, L. L. & 4 others, , 2023, In: EBioMedicine. 92, 18 p., 104625.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abnormal serum levels of magnesium, phosphate, and zinc in ICU patients—Characteristics, management, and outcomes: The WhyTrace cohort study
Vesterlund, G. K., Thorsen-Meyer, H. C., Møller, Morten Hylander, Brunak, Søren, Strøm, T., Perner, Anders & Kaas-Hansen, Benjamin Skov, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 925-935 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage
Westergaard, D., Steinthorsdottir, V., Stefansdottir, L., Rohde, P. D., Wu, X., Geller, F., Tyrmi, J., Havulinna, A. S., Navais, P. S., Flatley, C., Ostrowski, S. R., Pedersen, O. B., Erikstrup, C., Sørensen, E., Mikkelsen, C., Brun, M. T., Jensen, B. A., Brodersen, T., Ullum, H., Magnus, P. & 8 others, , 2023, medRxiv, 51 p. (medRxiv).Research output: Working paper › Preprint
- Published
The promise of digital healthcare technologies
Yeung, A. W. K., Torkamani, A., Butte, A. J., Glicksberg, B. S., Schuller, B., Rodriguez, B., Ting, D. S. W., Bates, D., Schaden, E., Peng, H., Willschke, H., van der Laak, J., Car, J., Rahimi, K., Celi, L. A., Banach, M., Kletecka-Pulker, M., Kimberger, O., Eils, R., Islam, S. M. S. & 5 others, , 2023, In: Frontiers in Public Health. 11, 12 p., 1196596.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
Reduced vitamin D-induced cathelicidin production and killing of Mycobacterium tuberculosis in macrophages from a patient with a non-functional vitamin D receptor: A case report
Al-Jaberi, F. A. H., Crone, C. G., Lindenstrøm, T., Arildsen, Nicolai Skovbjerg, Lindeløv, E. S., Aagaard, L., Gravesen, E., Mortensen, R., Andersen, A. B., Ølgaard, Klaus, Hjaltelin, Jessica Xin, Brunak, Søren, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2022, In: Frontiers in Immunology. 13, 9 p., 1038960.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variants Close to TTN, NKX2-5, and MYH6 Associate With AVNRT
Andreasen, L., Ahlberg, G., Ægisdóttir, H. M., Sveinbjörnsson, G., Lundegaard, P. R., Hartmann, J. P., Paludan-Müller, C., Hadji-Turdeghal, K., Ghouse, J., Pehrson, S., Jensen, H. K., Riahi, S., Hansen, J., Sandgaard, N., Sørensen, E., Banasik, K., Sækmose, S. G., Bruun, M. T., Hjalgrim, H., Erikstrup, C. & 18 others, , 2022, In: Circulation Research. 131, 10, p. 862-865Research output: Contribution to journal › Letter › Research › peer-review
- Published
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
Bjornsdottir, G., Stefansdottir, L., Thorleifsson, G., Sulem, P., Norland, K., Ferkingstad, E., Oddsson, A., Zink, F., Lund, S. H., Nawaz, M. S., Bragi Walters, G., Skuladottir, A. T., Gudjonsson, S. A., Einarsson, G., Halldorsson, G. H., Bjarnadottir, V., Sveinbjornsson, G., Helgadottir, A., Styrkarsdottir, U., Gudmundsson, L. J. & 26 others, , 2022, In: Nature Communications. 13, 13 p., 634.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the effect of donor sex on red blood cell transfused patient mortality: A retrospective cohort study using a targeted learning and emulated trials-based approach
Bruun-Rasmussen, P., Andersen, Per Kragh, Banasik, Karina, Brunak, Søren & Johansson, Pär Ingemar , 2022, In: EClinicalMedicine. 51, 10 p., 101628.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intervening on the Storage Time of RBC Units and its Effects on Adverse Recipient Outcomes using Real-World Data
Bruun-Rasmussen, P., Andersen, Per Kragh, Banasik, Karina, Brunak, Søren & Johansson, Pär Ingemar , 2022, In: Blood. 139, 25, p. 3647–3654Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Randomized Phase II Study of Nivolumab with or Without Ipilimumab Combined with Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC)
Chen, I. M., Johansen, Julia Sidenius, Theile, S., Hjaltelin, Jessica Xin, Novitski, Sif Ingibergsdóttir, Brunak, Søren, Hasselby, Jane Preuss, Willemoe, G. L., Lorentzen, T., Madsen, K., Jensen, B. V., Wilken, E. E., Geertsen, P., Behrens, C., Nolsøe, Christian, Hermann, K. L., Svane, Inge Marie & Nielsen, Dorte Lisbet, 2022, In: Journal of Clinical Oncology. 40, 27, p. 3180-3189Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global priorities for large-scale biomarker-based prospective cohorts
Collins, R., Balaconis, M. K., Brunak, Søren, Chen, Z., De Silva, M., Gaziano, J. M., Ginsburg, G. S., Jha, P., Kuri, P., Metspalu, A., Mulder, N. & Risch, N., 2022, In: Cell Genomics. 2, 6, 4 p., 100141.Research output: Contribution to journal › Comment/debate › Research
- Published
Type I Interferons Promote Germinal Centers Through B Cell Intrinsic Signaling and Dendritic Cell Dependent Th1 and Tfh Cell Lineages
Dahlgren, M. W., Plumb, A. W., Niss, K., Lahl, K., Brunak, Søren & Johansson-Lindbom, B., 2022, In: Frontiers in Immunology. 13, 18 p., 932388.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Degenhardt, F., Ellinghaus, D., Juzenas, S., Lerga-Jaso, J., Wendorff, M., Maya-Miles, D., Uellendahl-Werth, F., ElAbd, H., Rühlemann, M. C., Arora, J., Özer, O., Lenning, O. B., Myhre, R., Vadla, M. S., Wacker, E. M., Wienbrandt, L., Ortiz, A. B., Salazar, A., Chercoles, A. G., Palom, A. & 31 others, , 2022, In: Human Molecular Genetics. 31, 23, p. 3945-3966 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Classification of Left and Right Coronary Arteries in Coronary Angiographies Using Deep Learning
Eschen, Christian Kim, Banasik, Karina, Christensen, Alex Hørby, Chmura, Piotr Jaroslaw, Pedersen, F., Køber, Lars Valeur, Engstrøm, Thomas, Dahl, A. B., Brunak, Søren & Bundgård, Henning, 2022, In: Electronics (Switzerland). 11, 13, 9 p., 2087.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci
Ghouse, J., Tragante, V., Muhammad, A., Ahlberg, G., Skov, M. W., Roden, D. M., Jonsdottir, I., Andreasen, L., Lundegaard, P. R., Trudsø, L. C., Banasik, K., Brunak, S., Ostrowski, S. R., Torp-Pedersen, C., Pedersen, O. V., Sørensen, E., Køber, L., Iversen, K., Thorsteinsdottir, U., Thorgeirsson, G. & 8 others, , 2022, In: European Heart Journal. 43, 45, p. 4707–4718Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The sequences of 150,119 genomes in the UK Biobank
Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F., Asgeirsdottir, M. & 27 others, , 2022, In: Nature. 607Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporal patterns of multi-morbidity in 570157 ischemic heart disease patients: a nationwide cohort study
Haue, Amalie Dahl, Armenteros, J. J. A., Holm, Peter Christoffer, Eriksson, R., Moseley, P. L., Køber, Lars Valeur, Bundgård, Henning & Brunak, Søren, 2022, In: Cardiovascular Diabetology. 21, 13 p., 87.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles - A Mendelian randomization analysis
Helgadottir, A., Thorleifsson, G., Snaebjarnarson, A., Stefansdottir, L., Sveinbjornsson, G., Tragante, V., Björnsson, E., Steinthorsdottir, V., Gretarsdottir, S., Helgason, H., Saemundsdottir, J., Olafsson, I., Thune, J. J., Axelsson Raja, A., Ghouse, J., Olesen, M. S., Christensen, A., Jacobsen, R. L., Dowsett, J., Bruun, M. T. & 18 others, , 2022, In: European Journal of Preventive Cardiology. 29, 18, p. 2374–2385Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The temporal association of hyperhidrosis and its comorbidities – a nationwide hospital-based cohort study
Henning, M. A. S., Reguant, R., Jørgensen, Isabella Friis, Andersen, Rune Kjærsgaard, Ibler, Kristina Sophie, Pedersen, Ole Birger Vesterager, Jemec, Gregor & Brunak, Søren, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 12, p. 2504-2511Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical, genetic, and experimental increase in soluble urokinase plasminogen activator receptor levels promotes atherosclerosis
Hindy, G., Tyrrell, D. J., Vasbinder, A., Wei, C., Presswalla, F., Wang, H., Blakely, P. K., Ozel, A. B., Graham, S. E., Holton, G. H., Dowsett, J., Fahed, A. C., Amadi, K-M., Erne, G. K., Tekumulla, A., Ismail, A., Launius, C., Sotoodehnia, N., Pankow, J. S., Thørner, L. W. & 22 others, , 2022, In: Journal of Clinical Investigation. 132, 24, 14 p., e158788.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eliciting drug safety signals from patient records: a language-agnostic approach
Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodriguez, C., Thorsen-Meyer, H., Gentile, S., Nielsen, A., Brunak, Søren, Jürgens, Gesche & Andersen, S., 2022, p. S15-S16. 2 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records
Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodríguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, In: Basic & clinical pharmacology & toxicology. 131, 4, p. 282-293 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records
Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodrìguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, Authorea, (Authorea Preprints).Research output: Working paper › Preprint
- Published
Machine Learning to Identify Patients at Risk of Inappropriate Dosing for Renal Risk Medications: A Critical Comment on Kaas-Hansen et al [Response to Letter]
Kaas-Hansen, Benjamin Skov, Leal Rodríguez, C., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2022, In: Clinical Epidemiology. 14, p. 765-766 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Using Machine Learning to Identify Patients at High Risk of Inappropriate Drug Dosing in Periods with Renal Dysfunction
Kaas-Hansen, Benjamin Skov, Leal Rodríguez, C., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2022, In: Clinical Epidemiology. 14, p. 213-223 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Established risk loci for systemic lupus erythematosus at NCF2, STAT4, TNPO3, IRF5 and ITGAM associate with distinct clinical manifestations: A Danish genome-wide association study
DBDS Genomic Consortium, D. G. C., 2022, In: Joint Bone Spine. 89, 4, 105357.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Reply to: Immortal time bias in the analysis of drug prescription trajectories
Mortensen, Laust Hvas & Brunak, Søren, 2022, In: npj Digital Medicine. 5, 1, 1 p., 191.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
- Published
Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors
Pérez-Alós, L., Armenteros, J. J. A., Madsen, J. R., Hansen, C. B., Jarlhelt, I., Hamm, S. R., Heftdal, L. D., Pries-Heje, M. M., Møller, D. L., Fogh, K., Hasselbalch, R. B., Rosbjerg, A., Brunak, S., Sørensen, E., Larsen, M. A. H., Ostrowski, S. R., Frikke-Schmidt, R., Bayarri-Olmos, R., Hilsted, L. M., Iversen, K. K. & 3 others, , 2022, In: Nature Communications. 13, 1, 11 p., 1614.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug interactions in hospital prescriptions in Denmark: Prevalence and associations with adverse outcomes
Rodríguez, C. L., Kaas-Hansen, Benjamin Skov, Eriksson, R., Biel, J. H., Belling, K. G., Andersen, Stig Ejdrup & Brunak, Søren, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 6, p. 632-642 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Saevarsdottir, S., Stefansdottir, L., Sulem, P., Thorleifsson, G., Ferkingstad, E., Rutsdottir, G., Glintborg, B., Westerlind, H., Grondal, G., Loft, I. C., Sorensen, S. B., Lie, B. A., Brink, M., Ärlestig, L., Arnthorsson, A. O., Baecklund, E., Banasik, K., Bank, S., Bjorkman, L. I., Ellingsen, T. & 31 others, , 2022, In: Annals of the Rheumatic Diseases. 81, 8, p. 1085-1095Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome
Skuladottir, A. T., Bjornsdottir, G., Ferkingstad, E., Einarsson, G., Stefansdottir, L., Nawaz, M. S., Oddsson, A., Olafsdottir, T. A., Saevarsdottir, S., Walters, G. B., Magnusson, S. H., Bjornsdottir, A., Sveinsson, O. A., Vikingsson, A., Hansen, T. F., Jacobsen, R. L., Erikstrup, C., Schwinn, M., Brunak, S., Banasik, K. & 11 others, , 2022, In: Nature Communications. 13, 1, 9 p., 1598.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SignalP 6.0 predicts all five types of signal peptides using protein language models
Teufel, Felix Georg, Almagro Armenteros, J. J., Johansen, A. R., Gíslason, M. H., Pihl, S. I., Tsirigos, Konstantinos, Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 2022, In: Nature Biotechnology. 40, p. 1023-1025Research output: Contribution to journal › Comment/debate › Research
- Published
Discrete-time survival analysis in the critically ill: a deep learning approach using heterogeneous data
Thorsen-Meyer, H., Placido, Davide, Kaas-Hansen, Benjamin Skov, Nielsen, A. P., Lange, Theis, Nielsen, A. B., Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Belling, K., Perner, Anders & Brunak, Søren, 2022, In: npj Digital Medicine. 5, 10 p., 142.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease
Uellendahl-Werth, F., Maj, C., Borisov, O., Juzenas, S., Wacker, E. M., Jorgensen, I. F., Steiert, T. A., Bej, S., Krawitz, P., Hoffmann, P., Schramm, C., Wolkenhauer, O., Banasik, K., Brunak, S., Schreiber, S., Karlsen, T. H., Degenhardt, F., Noethen, M., Franke, A., Folseraas, T. & 1 others, , 2022, In: Communications Biology. 5, 15 p., 80.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study
Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M. G., Musholt, P. B., Kurbasic, A., Masi, F. D., Tsirigos, K., Pedersen, H. K., Gudmundsdottir, V. & 31 others, , 2022, In: Cell Reports Medicine. 3, 1, 25 p., 100477.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Extrapolation of drug induced liver injury responses from cancer cell lines using machine learning approaches
Aguayo-Orozco, A., Brunak, Søren & Taboureau, O., 2021, In: Computational Toxicology. 17, 6 p., 100147.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimizing drug selection from a prescription trajectory of one patient
Aguayo-Orozco, A., Haue, Amalie Dahl, Jørgensen, Isabella Friis, Westergaard, D., Moseley, P. L., Mortensen, Laust Hvas & Brunak, Søren, 2021, In: npj Digital Medicine. 4, 1, 150.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired Vitamin D Signaling in T Cells From a Family With Hereditary Vitamin D Resistant Rickets
Al-Jaberi, F. A. H., Kongsbak-Wismann, Martin, Aguayo-Orozco, A., Krogh, Nicolai, Buus, Terkild Brink, Lopez, D. V., Rode, A. K. O., Gravesen, Eva, Ølgaard, Klaus, Brunak, Søren, Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 11 p., 684015.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Bell, S., Rigas, A. S., Magnusson, M. K., Ferkingstad, E., Allara, E., Bjornsdottir, G., Ramond, A., Sørensen, E., Halldorsson, G. H., Paul, D. S., Burgdorf, K. S., Eggertsson, H. P., Howson, J. M. M., Thørner, L. W., Kristmundsdottir, S., Astle, W. J., Erikstrup, C., Sigurdsson, J. K., Vuckovic, D., Dinh, K. M. & 31 others, , 2021, In: Communications Biology . 4, 1, 14 p., 156.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study
Bizzotto, R., Jennison, C., Jones, A. G., Kurbasic, A., Tura, A., Kennedy, G., Bell, J. D., Thomas, E. L., Frost, G., Eriksen, R., Koivula, R. W., Brage, S., Kaye, J., Hattersley, A. T., Heggie, A., McEvoy, D., 't Hart, L. M., Beulens, J. W., Elders, P., Musholt, P. B. & 28 others, , 2021, In: Diabetes Care. 44, 2, p. 511-518 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients
Bliddal, S., Banasik, Karina, Pedersen, Ole Birger Vesterager, Nissen, J., Cantwell, Lisa, Schwinn, M., Tulstrup, Morten Rytter, Westergaard, D., Ullum, H., Brunak, Søren, Tommerup, Niels, Feenstra, B., Geller, F., Ostrowski, Sisse Rye, Grønbæk, Kirsten, Nielsen, Claus Henrik, Nielsen, Susanne Dam & Feldt-Rasmussen, Ulla, 2021, In: Scientific Reports. 11, 13153.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrating Longitudinal Clinical and Baseline Multiomics Data for Predicting C-Peptide Progression in Newly Diagnosed Type 1 Diabetes: 1111-P
Brorsson, C., Armenteros, J. J. A., Mazzoni, G., Kaur, S., Schulte, A. M., Mathieu, C. & Brunak, Søren, 2021. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Detection of Molecular Signatures of Homologous Recombination Deficiency in Bladder Cancer
Pilmark, Judit Börcsök, Diossy, M., Sztupinszki, Z., Prosz, A., Tisza, V., Spisak, S., Rusz, O., Stormoen, D. R., Pappot, Helle, Csabai, I., Brunak, Søren, Mouw, K. W. & Szallasi, Z., 2021, In: Clinical Cancer Research. 27, 13, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer
Börcsök, J., Sztupinszki, Z., Bekele, R., Gao, S. P., Diossy, M., Samant, A. S., Dillon, K. M., Tisza, V., Spisák, S., Rusz, O., Csabai, I., Pappot, H., Frazier, Z. J., Konieczkowski, D. J., Liu, D., Vasani, N., Rodrigues, J. A., Solit, D. B., Hoffman-Censits, J. H., Plimack, E. R. & 10 others, , 2021, In: Clinical Cancer Research. 27, 7, p. 2011-2022 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor
Dowsett, J., Ferkingstad, E., Rasmussen, L. J. H., Thørner, L. W., Magnússon, M. K., Sugden, K., Thorleifsson, G., Frigge, M., Burgdorf, K. S., Ostrowski, S. R., Sørensen, E., Erikstrup, C., Pedersen, O. B., Hansen, T. F., Banasik, K., Brunak, S., Tragante, V., Lund, S. H., Stefansdottir, L., Gunnarson, B. & 10 others, , 2021, In: Communications Biology . 4, 1, p. 655Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Variants Near the Bradykinin Receptor B2 Gene With Angioedema in Patients Taking ACE Inhibitors
Ghouse, Jonas, Ahlberg, G., Andreasen, Laura Korsholm, Banasik, Karina, Brunak, Søren, Schwinn, M., Larsen, I. H., Petersen, O., Sørensen, E., Ullum, H., Rasmussen, E. R., Eriksson, N., Hallberg, P., Wadelius, M., Bundgård, Henning & Olesen, Morten Steen Salling, 2021, In: Journal of the American College of Cardiology. 78, 7, p. 696-709 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ELIXIR-EXCELERATE: establishing Europe's data infrastructure for the life science research of the future
ELIXIR-EXCELERATE Community, E. C., 2021, In: EMBO Journal. 40, 6, 9 p., e107409.Research output: Contribution to journal › Comment/debate › Research
- Published
The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies
Herrera, J. A. R., Thomsen, S. T., Jakobsen, L. S., Fagt, S., Banasik, Karina, Izarzugaza, J. M. G., Brunak, Søren & Pires, S. M., 2021, In: Food and Chemical Toxicology. 150, 112072.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-ordered comorbidity correlations identify patients at risk of mis- and overdiagnosis
Jørgensen, Isabella Friis & Brunak, Søren, 2021, In: npj Digital Medicine. 4, 10 p., 12.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12895347
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Identification of odorant-receptor interactions by global mapping of the human odorome
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
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A human gut microbial gene catalogue established by metagenomic sequencing
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