Søren Brunak
Professor
Brunak Group
Blegdamsvej 3B
2200 København N
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A Brief History of Protein Sorting Prediction
Nielsen, H., Tsirigos, Konstantinos, Brunak, Søren & von Heijne, G., 2019, In: The Protein Journal. 38, 3, p. 200-216 17 p.Research output: Contribution to journal › Review › Research › peer-review
A DNA structural atlas for Escherichia coli
Pedersen, A. G., Jensen, L. J., Brunak, Søren, Staerfeldt, H. H. & Ussery, D., 2000, In: Journal of Molecular Biology. 299, 4, p. 907-30 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Familial Cardiac Arrhythmia Syndrome with Widespread ST-Segment Depression
Bundgård, Henning, Jøns, C., Lodder, E. M., Izarzugaza, J. M. G., Romero Herrera, J. A., Pehrson, S., Tfelt-Hansen, Jacob, Ahlberg, G., Olesen, Morten Steen Salling, Holst, A. G., Wellens, H., de Villiers, C., Hastings, R., Stuart, G., Brunak, Søren, Wilde, A. A. M., Watkins, H. & Christensen, A. H., 2018, In: The New England Journal of Medicine. 379, 18, p. 1780-1781 2 p.Research output: Contribution to journal › Comment/debate › Research
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A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts
Westergaard, D., Stærfeldt, H., Tønsberg, C., Jensen, Lars Juhl & Brunak, Søren, 2018, In: PLoS Computational Biology. 14, 2, 16 p., e1005962.Research output: Contribution to journal › Journal article › Research › peer-review
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A computational approach to chemical etiologies of diabetes
Audouze, K. M. L., Brunak, Søren & Grandjean, P., 19 Sep 2013, In: Scientific Reports. 3, p. 2712 2712.Research output: Contribution to journal › Journal article › Research › peer-review
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A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links
Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories
Placido, D., Yuan, B., Hjaltelin, J. X., Zheng, C., Haue, A. D., Chmura, P. J., Yuan, C., Kim, J., Umeton, R., Antell, G., Chowdhury, A., Franz, A., Brais, L., Andrews, E., Marks, D. S., Regev, A., Ayandeh, S., Brophy, M. T., Do, N. V., Kraft, P. & 5 others, , 2023, In: Nature Medicine. 29, p. 1113-1122Research output: Contribution to journal › Journal article › Research › peer-review
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A generic deep convolutional neural network framework for prediction of receptor–ligand interactions - NetPhosPan: application to kinase phosphorylation prediction
Fenoy, E., Izarzugaza, J. M. G., Jurtz, V., Brunak, Søren & Nielsen, M., 2019, In: Bioinformatics. 35, 7, p. 1098-1107Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation
Dalgaard, M. D., Weinhold, N., Edsgärd, D., Silver, J. D., Pers, T. H., Nielsen, J. E., Jørgensen, N., Juul, A., Gerds, T. A., Giwercman, A., Giwercman, Y. L., Cohn-Cedermark, G., Virtanen, H. E., Toppari, J., Daugaard, G., Jensen, T. S., Brunak, S., Rajpert-De Meyts, E., Skakkebæk, N. E., Leffers, H. & 1 others, , 2012, In: Journal of Medical Genetics. 49, 1, p. 58-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide association study of social trust in 33,882 Danish blood donors
Sequeros, C. B., Hansen, T. F., Westergaard, D., Louloudis, I., Kalamajski, S., Röder, T., Rohde, P. D., Schwinn, M., Clemmensen, L. H., Didriksen, M., Nyegaard, M., Hjalgrim, H., Nielsen, K. R., Bruun, M. T., Ostrowski, S. R., Erikstrup, C., Mikkelsen, S., Sørensen, E., Pedersen, O. B. V., Brunak, S. & 3 others, , 2024, In: Scientific Reports. 14, 12 p., 1402.Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome
Skuladottir, A. T., Bjornsdottir, G., Ferkingstad, E., Einarsson, G., Stefansdottir, L., Nawaz, M. S., Oddsson, A., Olafsdottir, T. A., Saevarsdottir, S., Walters, G. B., Magnusson, S. H., Bjornsdottir, A., Sveinsson, O. A., Vikingsson, A., Hansen, T. F., Jacobsen, R. L., Erikstrup, C., Schwinn, M., Brunak, S., Banasik, K. & 11 others, , 2022, In: Nature Communications. 13, 1, 9 p., 1598.Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Bell, S., Rigas, A. S., Magnusson, M. K., Ferkingstad, E., Allara, E., Bjornsdottir, G., Ramond, A., Sørensen, E., Halldorsson, G. H., Paul, D. S., Burgdorf, K. S., Eggertsson, H. P., Howson, J. M. M., Thørner, L. W., Kristmundsdottir, S., Astle, W. J., Erikstrup, C., Sigurdsson, J. K., Vuckovic, D., Dinh, K. M. & 31 others, , 2021, In: Communications Biology . 4, 1, 14 p., 156.Research output: Contribution to journal › Journal article › Research › peer-review
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A genomic history of aboriginal Australia
Malaspinas, A. S., Westaway, M. C., Muller, C. E., Sousa, V. C., Lao, O., Alves, I., Bergström, A., Athanasiadis, G., Cheng, J. Y., Crawford, J. E., Heupink, T. H., Macholdt, E., Peischl, S., Rasmussen, S., Schiffels, S., Subramanian, S., Wright, J. L., Albrechtsen, A., Barbieri, C., Dupanloup, I. & 55 others, , 2016, In: Nature. 538, 7624, p. 207-214 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, M. C., 2010, In: Nature. 464, 7285, p. 59-65 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A large-cohort, longitudinal study determines pre-cancer disease routes across different cancer types
Hjaltelin, Jessica Xin, Helleberg, M., Jensen, A. B., Brunak, Søren & Lundgren, Jens, 2019, In: Cancer Research. 79, 4, p. 864-872Research output: Contribution to journal › Journal article › Research › peer-review
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A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes
Hansen, K. L., Hansen, N. T., Karlberg, E. O., Eklund, A. C., Roque, F. S., Donahoe, P. K., Szallasi, Z., Jensen, T. S. & Brunak, Søren, 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 52, p. 20870-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A nondegenerate code of deleterious variants in mendelian Loci contributes to complex disease risk
Blair, D. R., Lyttle, C. S., Mortensen, J. M., Bearden, C. F., Jensen, A. B., Khiabanian, H., Melamed, R., Rabadan, R., Bernstam, E. V., Brunak, Søren, Jensen, Lars Juhl, Nicolae, D., Shah, N. H., Grossman, R. L., Cox, N. J., White, K. P. & Rzhetsky, A., 26 Sep 2013, In: Cell. 155, 1, p. 70-80 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death
Rondas, D., Gudmundsdottir, V., D'Hertog, W., Crèvecoeur, I., Waelkens, E., Brunak, Søren, Mathieu, C. & Overbergh, L., Oct 2015, In: Proteomics - Clinical Applications. 9, 9-10, p. 938–952 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A scored human protein-protein interaction network to catalyze genomic interpretation
Li, T., Wernersson, R., Hansen, R. B., Horn, H., Mercer, J., Slodkowicz, G., Workman, C. T., Rigina, O., Rapacki, K., Stærfeldt, H. H., Brunak, Søren, Jensen, T. S. & Hansen, K. L., Jan 2017, In: Nature Methods. 14, 1, p. 61–64Research output: Contribution to journal › Letter › Research › peer-review
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A second update on mapping the human genetic architecture of COVID-19
Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, , 2023, In: Nature. 621, 7977, p. E7-E26 23 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing
Schjoldager, Katrine Ter-Borch Gram, Vester-Christensen, M. B., Goth, C. K., Petersen, T. N., Brunak, Søren, Bennett, Eric Paul, Levery, S. B. & Clausen, Henrik, 18 Nov 2011, In: Journal of Biological Chemistry. 286, 46, p. 40122-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A unidirectional mapping of ICD-8 to ICD-10 codes, for harmonized longitudinal analysis of diseases
Pedersen, M. K., Eriksson, R., Reguant, R., Collin, C., Pedersen, H. K., Sørup, Freja Karuna Hemmingsen, Simon, C., Birch, A. M., Larsen, Michael, Nielsen, A. P., Belling, K. & Brunak, Søren, 2023, In: European Journal of Epidemiology. 38, p. 1043–1052 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ARDD 2020: from aging mechanisms to interventions
Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, , 2020, In: Aging. 12, 24, p. 24486-24503 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Abnormal serum levels of magnesium, phosphate, and zinc in ICU patients—Characteristics, management, and outcomes: The WhyTrace cohort study
Vesterlund, G. K., Thorsen-Meyer, H. C., Møller, Morten Hylander, Brunak, Søren, Strøm, T., Perner, Anders & Kaas-Hansen, Benjamin Skov, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 925-935 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Accurate genotyping across variant classes and lengths using variant graphs
Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12895347
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2932
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Identification of odorant-receptor interactions by global mapping of the human odorome
Research output: Contribution to journal › Journal article › Research › peer-review
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2870
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
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1246
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A human gut microbial gene catalogue established by metagenomic sequencing
Research output: Contribution to journal › Journal article › Research › peer-review
Published