Søren Brunak
Professor
Brunak Group
Blegdamsvej 3B
2200 København N
- 2019
- Published
A Brief History of Protein Sorting Prediction
Nielsen, H., Tsirigos, Konstantinos, Brunak, Søren & von Heijne, G., 2019, In: The Protein Journal. 38, 3, p. 200-216 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A generic deep convolutional neural network framework for prediction of receptor–ligand interactions - NetPhosPan: application to kinase phosphorylation prediction
Fenoy, E., Izarzugaza, J. M. G., Jurtz, V., Brunak, Søren & Nielsen, M., 2019, In: Bioinformatics. 35, 7, p. 1098-1107Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large-cohort, longitudinal study determines pre-cancer disease routes across different cancer types
Hjaltelin, Jessica Xin, Helleberg, M., Jensen, A. B., Brunak, Søren & Lundgren, Jens, 2019, In: Cancer Research. 79, 4, p. 864-872Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1
Briand, E., Thomsen, Ragnar, Linnet, Kristian, Rasmussen, H. B., Brunak, Søren & Taboureau, O., 2019, In: Molecules. 24, 15, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combing the Hairball: Improving Visualization of miRNA-Target Interaction Networks
Russo, F., Hjaltelin, Jessica Xin, Romero Herrera, J. A. & Brunak, Søren, 2019, MicroRNA Target Identification: Methods and Protocols. Laganà, A. (ed.). Humana Press, p. 279-289 11 p. (Methods in Molecular Biology, Vol. 1970).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Comorbidity landscape of the Danish patient population affected by chromosome abnormalities
Jørgensen, Isabella Friis, Russo, F., Jensen, A. B., Westergaard, David, Lademann, M., Hjaltelin, Jessica Xin, Brunak, Søren & Belling, K., 2019, In: Genetics In Medicine. 21, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq
Gådin, J. R., Buil, A., Colantuoni, C., Jaffe, A. E., Nielsen, J., Shin, J., Hyde, T. M., Kleinman, J. E., Plath, N., Eriksson, P., Brunak, Søren, Didriksen, M., Weinberger, D. R., Folkersen, L. & BrainSeq Consortium, B. C., 2019, In: PLoS ONE. 14, 6, 16 p., e0217765.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contaminating viral sequences in high-throughput sequencing viromics: a linkage study of 700 sequencing libraries
Asplund, M., Kjartansdóttir, K. R., Mollerup, S., Vinner, L., Fridholm, H., Herrera, J. A. R., Friis-Nielsen, J., Hansen, T. A., Jensen, R. H., Nielsen, I. B., Richter, S. R., Rey-Iglesia, A., Matey-Hernandez, M. L., Alquezar-Planas, D. E., Olsen, P. V. S., Sicheritz-Pontén, T., Willerslev, E., Lund, O., Brunak, S., Mourier, T. & 3 others, , 2019, In: Clinical Microbiology and Infection. 25, 10, p. 1277-1285Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium
Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, T. H., Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, K. H., Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H. & 31 others, , 2019, In: Diabetologia. 62, 9, p. 1601-1615Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating heritability and genetic correlations from large health datasets in the absence of genetic data
Jia, G., Li, Y., Zhang, H., Chattopadhyay, I., Jensen, A. B., Blair, D. R., Davis, L., Robinson, P. N., Dahlen, T., Brunak, Søren, Benson, M., Edgren, G., Cox, N. J., Gao, X. & Rzhetsky, A., 2019, In: Nature Communications. 10, 11 p., 5508.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V. & 31 others, , 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types
Hjaltelin, Jessica Xin, Izarzugaza, J. M. G., Jensen, Lars Juhl, Russo, F., Westergaard, David & Brunak, Søren, 2019, In: npj Systems Biology and Applications. 5, 10 p., 27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identifying Sepsis Phenotypes
Moseley, P. L. & Brunak, Søren, 2019, In: J A M A: The Journal of the American Medical Association. 322, 14, p. 1416-1417 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Incorporating symptom data in longitudinal disease trajectories for more detailed patient stratification
Lademann, M., Lademann, M., Boeck Jensen, A. & Brunak, Søren, 2019, In: International Journal of Medical Informatics. 129, p. 107-113 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, K., Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, D., Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, S., Pedersen, C. B., Fuller Torrey, E., Werge, T., Bo Mortensen, P. & 2 others, , 2019, In: Brain, Behavior, and Immunity. 79, p. 152-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leveraging European infrastructures to access 1 million human genomes by 2022
Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, S., Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M. & 21 others, , 2019, In: Nature Reviews. Genetics. 20, p. 693-701 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining
Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, , 2019, In: eLife. 8, 19 p., e44941.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Migraine polygenic risk score associates with efficacy of migraine-specific drugs
Kogelman, L. J. A., Esserlind, A-L., Christensen, A. F., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B., Erikstrup, C., Hjalgrim, H., Ullum, H., Olesen, J., Hansen, T. F., Gudbjartsson, D., Gastafsson, O., Stefansson, K., Stefansson, H., Porsteinsdottir, U., Andersen, S., Banasik, K., Brunak, S. & 73 others, , 2019, In: Neurology: Genetics. 5, 6, 12 p., e364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patterns of co-occurrence of congenital heart defects follows distinct patterns
Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, Vibeke Elisabeth, Brunak, Søren & Larsen, Lars Allan, 2019, In: European Journal of Human Genetics. 26, p. 106 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Population-wide analysis of differences in disease progression patterns in men and women
Westergaard, David, Moseley, P., Sørup, Freja Karuna Hemmingsen, Baldi, P. & Brunak, Søren, 2019, In: Nature Communications. 10, 1, 14 p., 666.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediction of pancreatic fat and analysis of its determining factors using multi-omics datasets: an IMI DIRECTstudy
Karaderi, Tugce, Mazzoni, G., Brorsson, C., Westergaard, David, Banasik, Karina, Koivula, R., Thomas, L., Bell, J., Franks, P., Pearson, E. & Brunak, Søren, 2019, In: Diabetologia. 62, p. S166-S166Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Roadmap for a precision-medicine initiative in the Nordic region
Njølstad, P. R., Andreassen, O. A., Brunak, S., Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A., Mortensen, P. B., Palmgren, J. & 11 others, , 2019, In: Nature Genetics. 51, p. 924-930Research output: Contribution to journal › Comment/debate › Research
- Published
Survival prediction in intensive-care units based on aggregation of long-term disease history and acute physiology: a retrospective study of the Danish National Patient Registry and electronic patient records
Nielsen, A. B., Thorsen-Meyer, H. C., Belling, K., Nielsen, A. P., Thomas, Cecilia Engel, Chmura, Piotr Jaroslaw, Lademann, M., Moseley, P. L., Heimann, M., Dybdahl, L., Spangsege, L., Hulsen, P., Perner, Anders & Brunak, Søren, 2019, In: The Lancet Digital Health. 1, 2, p. e78-e89 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bio.tools registry of software tools and data resources for the life sciences
Ison, J., Ienasescu, H., Chmura, P., Rydza, E., Ménager, H., Kalaš, M., Schwämmle, V., Grüning, B., Beard, N., Lopez, R., Duvaud, S., Stockinger, H., Persson, B., Vařeková, R. S., Raček, T., Vondrášek, J., Peterson, H., Salumets, A., Jonassen, I., Hooft, R. & 16 others, , 2019, In: Genome Biology. 20, 1, 4 p., 164.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The use of systems biology in chemical risk assessment
Aguayo-Orozco, A., Taboureau, O. & Brunak, Søren, 2019, In: Current Opinion in Toxicology. 15, p. 48-54 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
sAOP: linking chemical stressors to adverse outcomes pathway networks
Aguayo-Orozco, A., Audouze, K., Siggaard, T., Barouki, R., Brunak, Søren & Taboureau, O., 2019, In: Bioinformatics. 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SignalP 5.0 improves signal peptide predictions using deep neural networks
Armenteros, J. J. A., Tsirigos, Konstantinos, Sønderby, C. K., Petersen, T. N., Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 18 Feb 2019, In: Nature Biotechnology. 37, 4, p. 420-423Research output: Contribution to journal › Journal article › Communication
Infrastruktur for klinik og forskning i Nationalt Genom Center
Ørntoft, T. F., Brunak, Søren, Jespergaard, C., Heickendorff, L., Grønkjær, K. & Løngreen, P., 1 Apr 2019, In: Ugeskrift for Laeger. 181, 7AResearch output: Contribution to journal › Journal article › Communication
- Published
DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors
Hansen, T. F., Banasik, K., Erikstrup, C., Pedersen, O. B., Westergaard, D., Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, P., Andersen, S., Nyegaard, M., Jemec, G. B. E., Olesen, J., Werge, T., Johansson, P. I., Sørensen, E. & 3 others, , 9 Jun 2019, In: BMJ Open. 9, 6, p. 1-7 7 p., e028401.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population
Nissen, J., Trabjerg, B., Pedersen, M. G., Banasik, K., Pedersen, O. B., Sørensen, E., Nielsen, K. R., Erikstrup, C., Petersen, M. S., Paarup, H. M., Bruun-Rasmussen, P., Westergaard, D., Hansen, T. F., Pedersen, C. B., Werge, T., Torrey, F., Hjalgrim, H., Mortensen, P. B., Yolken, R., Brunak, S. & 2 others, , Oct 2019, In: Psychoneuroendocrinology. 108, p. 150-154Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Heterogenous Treatment Response Trajectories to anti-IL6 Receptor Treatment in Rheumatoid Arthritis
Blair, J. P. M., Bager, C., Tang, M. H. E., Karsdal, M., Bay-Jensen, A. & Brunak, Søren, Oct 2019, In: Arthritis & Rheumatology. 71, S10, 3 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Population-wide disease trajectories in ischaemic heart disease
Haue, Amalie Dahl, Jørgensen, Isabella Friis, Christensen, A. H. C., Simon, C. S., Haakonsen, M. L. H., Russo, F. R., Rodriguez, C. L. R., Orozco, A. A. O., Siggard, T. S., Banasik, Karina, Weeke, P. E. W., Westergaard, David, Moseley, P. L. M., Bundgård, Henning & Brunak, Søren, Oct 2019, In: European Heart Journal. 40, S1, p. 1214-1214 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
High-Throughput Sequencing-Based Investigation of Viruses in Human Cancers by Multienrichment Approach
Mollerup, S., Asplund, M., Friis-Nielsen, J., Kjartansdóttir, K. R., Fridholm, H., Hansen, T. A., Herrera, J. A. R., Barnes, C. J., Jensen, R. H., Richter, S. R., Nielsen, I. B., Pietroni, C., Alquezar-Planas, D. E., Rey-Iglesia, A., Olsen, P. V. S., Rajpert-De Meyts, E., Groth-Pedersen, L., von Buchwald, C., Jensen, D. H., Gniadecki, R. & 20 others, , 15 Oct 2019, In: The Journal of Infectious Diseases. 220, 8, p. 1312-1324Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022
Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, S., Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M. & 21 others, , Nov 2019, In: Nature Reviews. Genetics. 20, 11, p. 702Research output: Contribution to journal › Comment/debate › Research
ID: 12895347
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Identification of odorant-receptor interactions by global mapping of the human odorome
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
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A human gut microbial gene catalogue established by metagenomic sequencing
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