Søren Brunak

Søren Brunak

Professor

ORCID: 0000-0003-0316-5866

Publication year:
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151 - 175 out of 347Page size: 25
  1. 2018
  2. Published

    Unexplored therapeutic opportunities in the human genome

    Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., von Mering, C., Muthas, D., Nguyen, D., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schürer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidovic, D., Waller, A., Westergaard, David, Yang, J. J. & Zahoránszky-Köhalmi, G., 2018, In: Nature Reviews. Drug Discovery. 17, 5, p. 317-332 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links

    Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Comorbidity landscape of the Danish patient population affected by chromosomal abnormalities

    Russo, F., Jørgensen, Isabella Friis, Westergaard, David, Jensen, A. B., Hjaltelin, Jessica Xin, Belling, K. & Brunak, Søren, 2018, In: European Journal of Human Genetics. 26, p. 697-698

    Research output: Contribution to journal › Conference abstract in journal › Research

  5. Published

    The Interplay of Non-coding RNAs and X Chromosome Inactivation in Human Disease

    Russo, F., De Masi, F., Brunak, Søren & Belling, K. G., 2018, Systems Biology. Rajewsky, N., Jurga, S. & Barciszewski, J. (eds.). Springer, p. 229-238 (RNA Technologies).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  6. Published

    miRandola 2017: a curated knowledge base of non-invasive biomarkers

    Russo, F., Di Bella, S., Vannini, F., Berti, G., Scoyni, F., Cook, H. V., Santos, A., Nigita, G., Bonnici, V., Laganà, A., Geraci, F., Pulvirenti, A., Giugno, R., De Masi, F., Belling, K., Jensen, Lars Juhl, Brunak, Søren, Pellegrini, M. & Ferro, A., 1 Jan 2018, In: Nucleic Acids Research. 46, D1, p. D354-D359 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Accurate genotyping across variant classes and lengths using variant graphs

    Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The governance structure for data access in the DIRECT consortium: an innovative medicines initiative (IMI) project

    Teare, H. J. A., de Masi, F., Banasik, Karina, Barnett, A., Herrgard, S., Jablonka, B., Postma, J. W. M., McDonald, T. J., Forgie, I., Chmura, P. J., Rydzka, E. K., Gupta, R., Brunak, Søren, Pearson, E. & Kaye, J., 2018, In: Life Sciences, Society and Policy. 14, 1, p. 1-17 20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers

    Tsafou, K., Katschnig, A. M., Radic-Sarikas, B., Mutz, C. N., Iljin, K., Schwentner, R., Kauer, M. O., Mühlbacher, K., Aryee, D. N. T., Westergaard, David, Haapa-Paananen, S., Fey, V., Superti-Furga, G., Toretsky, J., Brunak, Søren & Kovar, H., 2018, In: OncoTarget. 9, 57, p. 31018-31031 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The protein kinase SIK downregulates the polarity protein Par3

    Vanlandewijck, M., Dadras, M. S., Lomnytska, M., Mahzabin, T., Miller, M. L., Busch, C., Brunak, Søren, Heldin, C. & Moustakas, A., 2018, In: OncoTarget. 9, 5, p. 5716-5735 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Retinoic Acid Signaling in Thymic Epithelial Cells Regulates Thymopoiesis

    Wendland, K., Niss, K., Kotarsky, K., Wu, N. Y. H., White, A. J., Jendholm, L. J., Rivollier, A., Izarzugaza, J. M. G., Brunak, Søren, Holländer, G. A., Anderson, G., Sitnik, K. M. & Agace, W. W., 2018, In: Journal of Immunology. 201, 2, p. 524-532 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts

    Westergaard, David, Stærfeldt, H., Tønsberg, C., Jensen, Lars Juhl & Brunak, Søren, 2018, In: PLoS Computational Biology. 14, 2, 16 p., e1005962.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells

    Winge, S. B., Dalgaard, M. D., Belling, K. G., Jensen, J. M., Nielsen, J. E., Aksglaede, L., Schierup, M. H., Brunak, Søren, Skakkebæk, Niels Erik, Juul, Anders, Rajpert-De Meyts, E. & Almstrup, Kristian, 2018, In: Cell Death & Disease. 9, 6, 14 p., 586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Protective role of the vulture facial skin and gut microbiomes aid adaptation to scavenging

    Zepeda Mendoza, M. L., Roggenbuck, M., Manzano Vargas, K., Hansen, L. H., Brunak, Søren, Gilbert, M Thomas P & Sicheritz-Pontén, Thomas, 2018, In: Acta Veterinaria Scandinavica. 60, 1, p. 1-19 19 p., 61.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2019
  16. Published

    The use of systems biology in chemical risk assessment

    Aguayo-Orozco, A., Taboureau, O. & Brunak, Søren, 2019, In: Current Opinion in Toxicology. 15, p. 48-54 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    sAOP: linking chemical stressors to adverse outcomes pathway networks

    Aguayo-Orozco, A., Audouze, K., Siggaard, T., Barouki, R., Brunak, Søren & Taboureau, O., 2019, In: Bioinformatics. 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    SignalP 5.0 improves signal peptide predictions using deep neural networks

    Armenteros, J. J. A., Tsirigos, Konstantinos, Sønderby, C. K., Petersen, T. N., Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 18 Feb 2019, In: Nature Biotechnology. 37, 4, p. 420-423

    Research output: Contribution to journal › Journal article › Communication

  19. Published

    Contaminating viral sequences in high-throughput sequencing viromics: a linkage study of 700 sequencing libraries

    Asplund, M., Kjartansdóttir, K. R., Mollerup, S., Vinner, L., Fridholm, H., Herrera, J. A. R., Friis-Nielsen, J., Hansen, T. A., Jensen, R. H., Nielsen, I. B., Richter, S. R., Rey-Iglesia, A., Matey-Hernandez, M. L., Alquezar-Planas, D. E., Olsen, P. V. S., Sicheritz-Pontén, T., Willerslev, E., Lund, O., Brunak, S., Mourier, T. & 3 others, Nielsen, L. P., Izarzugaza, J. M. G. & Hansen, Anders Johannes, 2019, In: Clinical Microbiology and Infection. 25, 10, p. 1277-1285

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Identification of Heterogenous Treatment Response Trajectories to anti-IL6 Receptor Treatment in Rheumatoid Arthritis

    Blair, J. P. M., Bager, C., Tang, M. H. E., Karsdal, M., Bay-Jensen, A. & Brunak, Søren, Oct 2019, In: Arthritis & Rheumatology. 71, S10, 3 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  21. Published

    Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1

    Briand, E., Thomsen, Ragnar, Linnet, Kristian, Rasmussen, H. B., Brunak, Søren & Taboureau, O., 2019, In: Molecules. 24, 15, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders

    Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, K., Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, D., Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, S., Pedersen, C. B., Fuller Torrey, E., Werge, T., Bo Mortensen, P. & 2 others, Yolken, R. & Ullum, H., 2019, In: Brain, Behavior, and Immunity. 79, p. 152-158

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Patterns of co-occurrence of congenital heart defects follows distinct patterns

    Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, Vibeke Elisabeth, Brunak, Søren & Larsen, Lars Allan, 2019, In: European Journal of Human Genetics. 26, p. 106 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Published

    A generic deep convolutional neural network framework for prediction of receptor–ligand interactions - NetPhosPan: application to kinase phosphorylation prediction

    Fenoy, E., Izarzugaza, J. M. G., Jurtz, V., Brunak, Søren & Nielsen, M., 2019, In: Bioinformatics. 35, 7, p. 1098-1107

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq

    Gådin, J. R., Buil, A., Colantuoni, C., Jaffe, A. E., Nielsen, J., Shin, J., Hyde, T. M., Kleinman, J. E., Plath, N., Eriksson, P., Brunak, Søren, Didriksen, M., Weinberger, D. R., Folkersen, L. & BrainSeq Consortium, B. C., 2019, In: PLoS ONE. 14, 6, 16 p., e0217765.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors

    Hansen, T. F., Banasik, K., Erikstrup, C., Pedersen, O. B., Westergaard, D., Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, P., Andersen, S., Nyegaard, M., Jemec, G. B. E., Olesen, J., Werge, T., Johansson, P. I., Sørensen, E. & 3 others, Brunak, Søren, Ullum, H. & Burgdorf, Kristoffer Sølvsten, 9 Jun 2019, In: BMJ Open. 9, 6, p. 1-7 7 p., e028401.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Population-wide disease trajectories in ischaemic heart disease

    Haue, Amalie Dahl, Jørgensen, Isabella Friis, Christensen, A. H. C., Simon, C. S., Haakonsen, M. L. H., Russo, F. R., Rodriguez, C. L. R., Orozco, A. A. O., Siggard, T. S., Banasik, Karina, Weeke, P. E. W., Westergaard, David, Moseley, P. L. M., Bundgård, Henning & Brunak, Søren, Oct 2019, In: European Heart Journal. 40, S1, p. 1214-1214 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

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ID: 12895347