Replicating chromatin: a tale of histones

Research output: Contribution to journal › Review › Research › peer-review

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Replicating chromatin: a tale of histones. / Groth, Anja.

In: Biochemistry and Cell Biology, Vol. 87, No. 1, 2009, p. 51-63.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Groth, A 2009, 'Replicating chromatin: a tale of histones', Biochemistry and Cell Biology, vol. 87, no. 1, pp. 51-63. https://doi.org/10.1139/o08-102

APA

Groth, A. (2009). Replicating chromatin: a tale of histones. Biochemistry and Cell Biology, 87(1), 51-63. https://doi.org/10.1139/o08-102

Vancouver

Groth A. Replicating chromatin: a tale of histones. Biochemistry and Cell Biology. 2009;87(1):51-63. https://doi.org/10.1139/o08-102

Author

Groth, Anja. / Replicating chromatin: a tale of histones. In: Biochemistry and Cell Biology. 2009 ; Vol. 87, No. 1. pp. 51-63.

Bibtex

@article{c9f3e90009a611de8478000ea68e967b,
title = "Replicating chromatin: a tale of histones",
abstract = "Chromatin serves structural and functional roles crucial for genome stability and correct gene expression. This organization must be reproduced on daughter strands during replication to maintain proper overlay of epigenetic fabric onto genetic sequence. Nucleosomes constitute the structural framework of chromatin and carry information to specify higher-order organization and gene expression. When replication forks traverse the chromosomes, nucleosomes are transiently disrupted, allowing the replication machinery to gain access to DNA. Histone recycling, together with new deposition, ensures reassembly on nascent DNA strands. The aim of this review is to discuss how histones - new and old - are handled at the replication fork, highlighting new mechanistic insights and revisiting old paradigms.",
author = "Anja Groth",
year = "2009",
doi = "10.1139/o08-102",
language = "English",
volume = "87",
pages = "51--63",
journal = "Biochemistry and Cell Biology",
issn = "0829-8211",
publisher = "N R C Research Press",
number = "1",

}

RIS

TY - JOUR

T1 - Replicating chromatin: a tale of histones

AU - Groth, Anja

PY - 2009

Y1 - 2009

N2 - Chromatin serves structural and functional roles crucial for genome stability and correct gene expression. This organization must be reproduced on daughter strands during replication to maintain proper overlay of epigenetic fabric onto genetic sequence. Nucleosomes constitute the structural framework of chromatin and carry information to specify higher-order organization and gene expression. When replication forks traverse the chromosomes, nucleosomes are transiently disrupted, allowing the replication machinery to gain access to DNA. Histone recycling, together with new deposition, ensures reassembly on nascent DNA strands. The aim of this review is to discuss how histones - new and old - are handled at the replication fork, highlighting new mechanistic insights and revisiting old paradigms.

AB - Chromatin serves structural and functional roles crucial for genome stability and correct gene expression. This organization must be reproduced on daughter strands during replication to maintain proper overlay of epigenetic fabric onto genetic sequence. Nucleosomes constitute the structural framework of chromatin and carry information to specify higher-order organization and gene expression. When replication forks traverse the chromosomes, nucleosomes are transiently disrupted, allowing the replication machinery to gain access to DNA. Histone recycling, together with new deposition, ensures reassembly on nascent DNA strands. The aim of this review is to discuss how histones - new and old - are handled at the replication fork, highlighting new mechanistic insights and revisiting old paradigms.

U2 - 10.1139/o08-102

DO - 10.1139/o08-102

M3 - Review

C2 - 19234523

VL - 87

SP - 51

EP - 63

JO - Biochemistry and Cell Biology

JF - Biochemistry and Cell Biology

SN - 0829-8211

IS - 1

ER -

ID: 11085319