Protein interaction-based genome-wide analysis of incident coronary heart disease

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Protein interaction-based genome-wide analysis of incident coronary heart disease. / Jensen, Majken K; Pers, Tune H; Dworzynski, Piotr; Girman, Cynthia J; Brunak, Søren; Rimm, Eric B.

In: Circulation: Cardiovascular Genetics, Vol. 4, No. 5, 2011, p. 549-56.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Jensen, MK, Pers, TH, Dworzynski, P, Girman, CJ, Brunak, S & Rimm, EB 2011, 'Protein interaction-based genome-wide analysis of incident coronary heart disease', Circulation: Cardiovascular Genetics, vol. 4, no. 5, pp. 549-56. https://doi.org/10.1161/CIRCGENETICS.111.960393

APA

Jensen, M. K., Pers, T. H., Dworzynski, P., Girman, C. J., Brunak, S., & Rimm, E. B. (2011). Protein interaction-based genome-wide analysis of incident coronary heart disease. Circulation: Cardiovascular Genetics, 4(5), 549-56. https://doi.org/10.1161/CIRCGENETICS.111.960393

Vancouver

Jensen MK, Pers TH, Dworzynski P, Girman CJ, Brunak S, Rimm EB. Protein interaction-based genome-wide analysis of incident coronary heart disease. Circulation: Cardiovascular Genetics. 2011;4(5):549-56. https://doi.org/10.1161/CIRCGENETICS.111.960393

Author

Jensen, Majken K ; Pers, Tune H ; Dworzynski, Piotr ; Girman, Cynthia J ; Brunak, Søren ; Rimm, Eric B. / Protein interaction-based genome-wide analysis of incident coronary heart disease. In: Circulation: Cardiovascular Genetics. 2011 ; Vol. 4, No. 5. pp. 549-56.

Bibtex

@article{8c3c62da294d4616ad4be5150cd49ca4,
title = "Protein interaction-based genome-wide analysis of incident coronary heart disease",
abstract = "Network-based approaches may leverage genome-wide association (GWA) analysis by testing for the aggregate association across several pathway members. We aimed to examine if networks of genes that represent experimentally determined protein-protein interactions (PPIs) are enriched in genes associated with risk of coronary heart disease (CHD).",
keywords = "Adult, Aged, Animals, Blood Pressure, Case-Control Studies, Coronary Disease, Female, Genetic Loci, Genome-Wide Association Study, Genotype, Humans, Incidence, Male, Mice, Mice, Knockout, Middle Aged, Polymorphism, Single Nucleotide, Protein Interaction Mapping, Receptors, Adrenergic, beta-1, Risk Factors",
author = "Jensen, {Majken K} and Pers, {Tune H} and Piotr Dworzynski and Girman, {Cynthia J} and S{\o}ren Brunak and Rimm, {Eric B}",
year = "2011",
doi = "10.1161/CIRCGENETICS.111.960393",
language = "English",
volume = "4",
pages = "549--56",
journal = "Circulation: Cardiovascular Genetics",
issn = "1942-325X",
publisher = "Lippincott Williams & Wilkins",
number = "5",

}

RIS

TY - JOUR

T1 - Protein interaction-based genome-wide analysis of incident coronary heart disease

AU - Jensen, Majken K

AU - Pers, Tune H

AU - Dworzynski, Piotr

AU - Girman, Cynthia J

AU - Brunak, Søren

AU - Rimm, Eric B

PY - 2011

Y1 - 2011

N2 - Network-based approaches may leverage genome-wide association (GWA) analysis by testing for the aggregate association across several pathway members. We aimed to examine if networks of genes that represent experimentally determined protein-protein interactions (PPIs) are enriched in genes associated with risk of coronary heart disease (CHD).

AB - Network-based approaches may leverage genome-wide association (GWA) analysis by testing for the aggregate association across several pathway members. We aimed to examine if networks of genes that represent experimentally determined protein-protein interactions (PPIs) are enriched in genes associated with risk of coronary heart disease (CHD).

KW - Adult

KW - Aged

KW - Animals

KW - Blood Pressure

KW - Case-Control Studies

KW - Coronary Disease

KW - Female

KW - Genetic Loci

KW - Genome-Wide Association Study

KW - Genotype

KW - Humans

KW - Incidence

KW - Male

KW - Mice

KW - Mice, Knockout

KW - Middle Aged

KW - Polymorphism, Single Nucleotide

KW - Protein Interaction Mapping

KW - Receptors, Adrenergic, beta-1

KW - Risk Factors

U2 - 10.1161/CIRCGENETICS.111.960393

DO - 10.1161/CIRCGENETICS.111.960393

M3 - Journal article

C2 - 21880673

VL - 4

SP - 549

EP - 556

JO - Circulation: Cardiovascular Genetics

JF - Circulation: Cardiovascular Genetics

SN - 1942-325X

IS - 5

ER -

ID: 40804272