A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks. / Bartke, Till; Groth, Anja.

In: Molecular & Cellular Oncology, Vol. 6, No. 4, 1605820, 2019.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bartke, T & Groth, A 2019, 'A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks', Molecular & Cellular Oncology, vol. 6, no. 4, 1605820. https://doi.org/10.1080/23723556.2019.1605820

APA

Bartke, T., & Groth, A. (2019). A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks. Molecular & Cellular Oncology, 6(4), [1605820]. https://doi.org/10.1080/23723556.2019.1605820

Vancouver

Bartke T, Groth A. A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks. Molecular & Cellular Oncology. 2019;6(4). 1605820. https://doi.org/10.1080/23723556.2019.1605820

Author

Bartke, Till ; Groth, Anja. / A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks. In: Molecular & Cellular Oncology. 2019 ; Vol. 6, No. 4.

Bibtex

@article{2557e1d07bf142e19d616990ed7707bd,
title = "A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks",
abstract = "Mutations caused by DNA damage are a main driver of cancer. We discovered that recognition of newly synthesised histone H4 directs breast cancer type 1 susceptibility protein (BRCA1) to post-replicative chromatin. The switch from mutagenic to error-free DNA double strand break repair by homologous recombination is therefore controlled by chromatin.",
author = "Till Bartke and Anja Groth",
year = "2019",
doi = "10.1080/23723556.2019.1605820",
language = "English",
volume = "6",
journal = "Molecular & Cellular Oncology",
issn = "2372-3556",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks

AU - Bartke, Till

AU - Groth, Anja

PY - 2019

Y1 - 2019

N2 - Mutations caused by DNA damage are a main driver of cancer. We discovered that recognition of newly synthesised histone H4 directs breast cancer type 1 susceptibility protein (BRCA1) to post-replicative chromatin. The switch from mutagenic to error-free DNA double strand break repair by homologous recombination is therefore controlled by chromatin.

AB - Mutations caused by DNA damage are a main driver of cancer. We discovered that recognition of newly synthesised histone H4 directs breast cancer type 1 susceptibility protein (BRCA1) to post-replicative chromatin. The switch from mutagenic to error-free DNA double strand break repair by homologous recombination is therefore controlled by chromatin.

U2 - 10.1080/23723556.2019.1605820

DO - 10.1080/23723556.2019.1605820

M3 - Journal article

C2 - 31211233

VL - 6

JO - Molecular & Cellular Oncology

JF - Molecular & Cellular Oncology

SN - 2372-3556

IS - 4

M1 - 1605820

ER -

ID: 223130078