Søren Brunak

Søren Brunak

Professor

ORCID: 0000-0003-0316-5866

Publication year:
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201 - 250 out of 342Page size: 50
  1. 2018
  2. Published

    Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells

    Winge, S. B., Dalgaard, M. D., Belling, K. G., Jensen, J. M., Nielsen, J. E., Aksglaede, L., Schierup, M. H., Brunak, Søren, Skakkebæk, Niels Erik, Juul, Anders, Rajpert-De Meyts, E. & Almstrup, Kristian, 2018, In: Cell Death & Disease. 9, 6, 14 p., 586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Unexplored therapeutic opportunities in the human genome

    Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., von Mering, C., Muthas, D., Nguyen, D., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schürer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidovic, D., Waller, A., Westergaard, David, Yang, J. J. & Zahoránszky-Köhalmi, G., 2018, In: Nature Reviews. Drug Discovery. 17, 5, p. 317-332 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  4. 2017

  5. Legacy data sharing to improve drug safety assessment: the eTOX project

    Sanz, F., Pognan, F., Steger-Hartmann, T., Díaz, C., Cases, M., Pastor, M., Marc, P., Wichard, J., Briggs, K., Watson, D. K., Kleinöder, T., Yang, C., Amberg, A., Beaumont, M., Brookes, A. J., Brunak, S., Cronin, M. T. D., Ecker, G. F., Escher, S., Greene, N. & 17 others, Guzmán, A., Hersey, A., Jacques, P., Lammens, L., Mestres, J., Muster, W., Northeved, H., Pinches, M., Saiz, J., Sajot, N., Valencia, A., van der Lei, J., Vermeulen, N. P. E., Vock, E., Wolber, G., Zamora, I. & eTOX, E., Dec 2017, In: Nature Reviews. Drug Discovery. 16, 12, p. 811-812 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Protein features as determinants of wild-type glycoside hydrolase thermostability

    Geertz-Hansen, H. M., Kiemer, L., Nielsen, M., Stanchev, K., Blom, N., Brunak, Søren & Petersen, T. N., Nov 2017, In: Proteins: Structure, Function, and Bioinformatics. 85, 11, p. 2036-2044 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Assembly and analysis of 100 full MHC haplotypes from the Danish population

    Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R. & 39 others, Ye, W., Rao, J., Guo, X., Sun, J., Cao, H., Ye, C., Beusekom, J. V., Espeseth, T., Flindt, E., Halager, A. E., Hellard, S. L., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, D., Yadav, R., Li, N., Xu, X., Hansen, Torben, Bolund, L., Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Gupta, R., Rasmussen, Simon, Børglum, A. D., Wang, J., Eiberg, Hans Rudolf Lytchoff, Kristiansen, Karsten, Brunak, Søren & Schierup, M. H., Sep 2017, In: Genome Research. 27, 9, p. 1597-1607 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Lapatinib potentiates cytotoxicity of  YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter

    Radic-Sarikas, B., Halasz, M., Huber, K. V. M., Winter, G. E., Tsafou, K. P., Papamarkou, T., Brunak, Søren, Kolch, W. & Superti-Furga, G., 8 Jun 2017, In: Scientific Reports. 7, 1, p. 3091

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Voigt, A. Y., Vestergaard, H., Hercog, R., Costea, P. I., Kultima, J. R., Li, J., Jørgensen, T., Levenez, F. & 10 others, Doré, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Ehrlich, S. D., Bork, P., Pedersen, Oluf Borbye & MetaHIT consortium, M. C., 3 May 2017, In: Nature. 545, 116, 1 p., 22318.

    Research output: Contribution to journal › Comment/debate › Research

  10. Published

    Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents

    Lottrup, G., Belling, K., Leffers, H., Nielsen, J. E., Dalgaard, M. D., Juul, Anders, Skakkebæk, Niels Erik, Brunak, Søren & Meyts, E. R., 1 May 2017, In: Molecular Human Reproduction. 23, 5, p. 339-354 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity

    Belling, K., Russo, F., Jensen, A. B., Dalgaard, M. D., Westergaard, David, Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders & Brunak, Søren, 1 Apr 2017, In: Human Molecular Genetics. 26, 7, p. 1219-1229 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

    Folkersen, L., Fauman, E., Sabater-Lleal, M., Strawbridge, R. J., Frånberg, M., Sennblad, B., Baldassarre, D., Veglia, F., Humphries, S. E., Rauramaa, R., de Faire, U., Smit, A. J., Giral, P., Kurl, S., Mannarino, E., Enroth, S., Johansson, Å., Enroth, S. B., Gustafsson, S., Lind, L. & 13 others, Lindgren, C. M., Morris, A. P., Giedraitis, V., Silveira, A., Franco-Cereceda, A., Tremoli, E., Gyllensten, U., Ingelsson, E., Brunak, Søren, Eriksson, P., Ziemek, D., Hamsten, A. & Mälarstig, A., Apr 2017, In: P L o S Genetics. 13, 4, 21 p., e1006706.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer

    Francavilla, C., Lupia, M., Tsafou, K., Villa, A., Kowalczyk, K., Rakownikow Jersie-Christensen, R., Bertalot, G., Confalonieri, S., Brunak, Søren, Jensen, Lars Juhl, Cavallaro, U. & Olsen, Jesper Velgaard, 28 Mar 2017, In: Cell Reports. 18, 13, p. 3242-3256 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations

    Kirk, I. K., Weinhold, N., Belling, K., Skakkebæk, Niels Erik, Jensen, T. S., Leffers, H., Juul, Anders & Brunak, Søren, 22 Mar 2017, In: Cell Systems. 4, 3, 11 p., 357-364.e3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis

    Crèvecoeur, I., Gudmundsdottir, V., Vig, S., Marques Câmara Sodré, F., D'Hertog, W., Fierro, A. C., Van Lommel, L., Gysemans, C., Marchal, K., Waelkens, E., Schuit, F., Brunak, Søren, Overbergh, L. & Mathieu, C., Mar 2017, In: Diabetologia. 60, 3, p. 475-489 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Cutavirus in cutaneous malignant melanoma

    Mollerup, S., Fridholm, E. M. H., Vinner, Lasse, Kjartansdóttir, K. R., Friis-Nielsen, J., Asplund, M., Romero, J. A. H., Steiniche, T., Mourier, T., Brunak, Søren, Willerslev, Eske, Izarzugaza, J. M. G., Hansen, Anders Johannes & Nielsen, L. P., Feb 2017, In: Emerging Infectious Diseases . 23, 2, p. 363-365 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  17. Published

    Nomenclature for alleles of the human carboxylesterase 1 gene

    INDICES Consortium, I. C., 1 Jan 2017, In: Pharmacogenetics and Genomics. 27, 2, p. 78-80 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  18. Published

    A scored human protein-protein interaction network to catalyze genomic interpretation

    Li, T., Wernersson, R., Hansen, R. B., Horn, H., Mercer, J., Slodkowicz, G., Workman, C. T., Rigina, O., Rapacki, K., Stærfeldt, H. H., Brunak, Søren, Jensen, T. S. & Hansen, K. L., Jan 2017, In: Nature Methods. 14, 1, p. 61–64

    Research output: Contribution to journal › Letter › Research › peer-review

  19. Published

    Pharos: Collating protein information to shed light on the druggable genome

    Nguyen, D-T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., Liu, G., Ma'ayan, A., Mandava, G., Mani, S., Mehta, S., Overington, J., Patel, J., Rouillard, A. D., Schürer, S., Sheils, T. & 10 others, Simeonov, A., Sklar, L. A., Southall, N., Ursu, O., Vidovic, D., Waller, A., Yang, J., Jadhav, A., Oprea, T. I. & Guha, R., Jan 2017, In: Nucleic Acids Research. 45, D1, p. D995–D1002

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

    Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    MicroRNAs, Regulatory Networks, and Comorbidities: Decoding Complex Systems

    Russo, F., Belling, K., Jensen, A. B., Scoyni, F., Brunak, Søren & Pellegrini, M., 2017, In: Methods in molecular biology (Clifton, N.J.). 1580, p. 281-295 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes

    Pedersen, H. K., Gudmundsdottir, V. & Brunak, Søren, 2017, In: Frontiers in Genetics. 8, 43.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour

    Hay-Schmidt, Anders, Finkielman, O. T. E., Jensen, Benjamin Anderschou Holbech, Høgsbro, C. F., Holm, J. B., Johansen, K. H., Jensen, T. K., Andrade, A. M., Swan, S. H., Bornehag, C., Brunak, Søren, Jegou, B., Kristiansen, Karsten & Kristensen, D. M., 2017, In: Reproduction. 154, 2, p. 145-152 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

    Sørensen, L. M., Jensen, J. M., Petersen, B., Sibbesen, J. A., Liu, S., Villesen, P., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., Ye, W., Rao, J., Guo, X. & 39 others, Sun, J., Cao, H., Ye, C., van Beusekom, J., Espeseth, T., Flindt, E., Friborg, R. M., Halager, A. E., Le Hellard, S., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Mailund, T., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, David, Yadav, R., Li, N., Xu, X., Hansen, Torben, Krogh, Anders, Bolund, L., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Gupta, R., Rasmussen, Simon, Besenbacher, S., Børglum, A. D., Wang, J., Eiberg, Hans Rudolf Lytchoff, Kristiansen, Karsten, Brunak, Søren & Schierup, M. H., 2017, In: Nature. 548, 7665, p. 87-91 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  25. Published

    The impact of the protein interactome on the syntenic structure of mammalian genomes

    Kirk, I. K., Weinhold, N., Brunak, Søren & Belling, K., 2017, In: PLOS ONE. 12, 9, 14 p., e0179112.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2016
  27. Published

    Diagnosis trajectories of prior multi-morbidity predict sepsis mortality

    Beck, M. K., Jensen, A. B., Nielsen, A. B., Perner, Anders, Moseley, P. L. & Brunak, Søren, 4 Nov 2016, In: Scientific Reports. 6, 9 p., 36624.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Network biology concepts in complex disease comorbidities

    Hjaltelin, Jessica Xin, Thomas, Cecilia Engel & Brunak, Søren, Oct 2016, In: Nature Reviews. Genetics. 17, p. 615–629

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    The hunt for fatal myocardial infarction biomarkers: predictive circulating microRNAs

    Russo, F., Rizzo, M., Belling, K., Brunak, Søren & Folkersen, L., Oct 2016, In: Journal of Translational Medicine. 4, Suppl 1, 4 p., S1.

    Research output: Contribution to journal › Editorial › Research

  30. Published

    Transcriptional interactions suggest niche segregation among microorganisms in the human gut

    Plichta, D. R., Juncker, A. S., Bertalan, M., Rettedal, E., Gautier, L., Varela, E., Manichanh, C., Fouqueray, C., Levenez, F., Nielsen, T., Doré, J., Machado, A. M. D., de Evgrafov, M. C. R., Hansen, T., Jørgensen, T., Bork, P., Guarner, F., Pedersen, O., Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium, Sommer, M. O. A. & 4 others, Ehrlich, S. D., Sicheritz-Pontén, T., Brunak, Søren & Nielsen, H. B., 26 Aug 2016, In: Nature Microbiology. 1, p. 1-6 6 p., 16152.

    Research output: Contribution to journal › Letter › Research › peer-review

  31. Published

    KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily

    Pons, T., Vazquez, M., Matey-Hernandez, M. L., Brunak, Søren, Valencia, A. & Izarzugaza, J. M., 23 Jun 2016, In: BMC Genomics. 17, Suppl 2, 11 p., 396.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches

    Nzabonimpa, G. S., Rasmussen, Henrik Berg, Brunak, Søren, Taboureau, O. & INDICES Consortium, I. C., Jun 2016, In: Drug Metabolism and Personalized Therapy. 31, 2, p. 97-106 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Familial Atrial Septal Defect and Sudden Cardiac Death: Identification of a Novel NKX2-5 Mutation and a Review of the Literature

    Ellesøe, S. G., Johansen, M. M., Bjerre, J. V., Hjortdal, V. E., Brunak, Søren & Larsen, Lars Allan, 1 May 2016, In: Congenital Heart Disease. 11, 3, p. 283–290 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

    Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H-J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M. & 26 others, Halfvarson, J., Jensen, A. B., Lieb, W., Degenhardt, F., Forstner, A. J., Hofmann, A., Schreiber, S., Mrowietz, U., Juran, B. D., Lazaridis, K. N., Brunak, Søren, Dale, A. M., Trembath, R. C., Weidinger, S., Weichenthal, M., Ellinghaus, E., Elder, J. T., Barker, J. N. W. N., Andreassen, O. A., McGovern, D. P., Karlsen, T. H., Barrett, J. C., Parkes, M., Brown, M. A., Franke, A. & International IBD Genetics Consortium (IIBDGC), I. I. G. C. (., May 2016, In: Nature Genetics. 48, 5, p. 510-521 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    How Suitable Are Registry Data for Recurrence Risk Calculations? Validation of Diagnoses on 1,593 Families With Congenital Heart Disease

    Ellesøe, S. G., Jensen, A. B., Ängquist, Lars, Hjortdal, V. E., Larsen, Lars Allan & Brunak, Søren, Mar 2016, In: World journal for pediatric & congenital heart surgery. 7, 2, p. 169-77 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    wKinMut-2: Identification and Interpretation of Pathogenic Variants in Human Protein Kinases

    Vazquez, M., Pons, T., Brunak, Søren, Valencia, A. & Izarzugaza, J. M. G., Jan 2016, In: Human Mutation. 37, 1, p. 36-42 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    A genomic history of aboriginal Australia

    Malaspinas, A. S., Westaway, M. C., Muller, C. E., Sousa, V. C., Lao, O., Alves, I., Bergström, A., Athanasiadis, G., Cheng, J. Y., Crawford, J. E., Heupink, T. H., Macholdt, E., Peischl, S., Rasmussen, S., Schiffels, S., Subramanian, S., Wright, J. L., Albrechtsen, A., Barbieri, C., Dupanloup, I. & 55 others, Eriksson, A., Margaryan, Ashot, Moltke, Ida, Pugach, I., Korneliussen, Thorfinn Sand, Levkivskyi, I. P., Moreno Mayar, J. Víctor, Ni, S., Racimo, F., Sikora, Martin, Xue, Y., Aghakhanian, F. A., Brucato, N., Brunak, Søren, Campos, P., Clark, W., Ellingvåg, S., Fourmile, G., Gerbault, P., Injie, D., Koki, G., Leavesley, M., Logan, B., Lynch, A., Matisoo-Smith, E. A., McAllister, P. J., Mentzer, A. J., Metspalu, M., Migliano, A. B., Murgha, L., Phipps, M. E., Pomat, W., Reynolds, D., Ricaut, F., Siba, P., Thomas, M. G., Wales, T., Wall, C. M., Oppenheimer, S. J., Tyler-Smith, C., Durbin, R., Dortch, J., Manica, A., Schierup, M. H., Foley, R. A., Lahr, M. M., Bowern, C., Wall, J. D., Mailund, T., Stoneking, M., Nielsen, Rasmus, Sandhu, M. S., Excoffier, L., Lambert, D. M. & Willerslev, Eske, 2016, In: Nature. 538, 7624, p. 207-214 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    ChemProt-3.0: a global chemical biology diseases mapping

    Kringelum, J. V., Kjærulff, S. K., Brunak, Søren, Lund, O., Oprea, T. I. & Taboureau, O. T., 2016, In: Database: The Journal of Biological Databases and Curation. 2016, 7 p., bav123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Human gut microbes impact host serum metabolome and insulin sensitivity

    Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., Vieira-Silva, S. & 14 others, Jørgensen, T., Holm, J. B., Trošt, K., Kristiansen, Karsten, Brix, Susanne, Raes, J., Wang, J., Hansen, Torben, Bork, P., Brunak, Søren, Oresic, M., Ehrlich, S. D., Pedersen, Oluf Borbye & MetaHIT Consortium, M. C., 2016, In: Nature. 535, 7612, p. 376-381 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Identification of known and novel recurrent viral sequences in data from multiple patients and multiple cancers

    Friis-Nielsen, J., Kjartansdóttir, K. R., Mollerup, S., Asplund, M., Mourier, T., Jensen, R. H., Hansen, T. A., Rey de la Iglesia, A., Richter, S. R., Nielsen, I. B., Alquezar Planas, D. E., Olsen, P. V. S., Vinner, L., Fridholm, E. M. H., Nielsen, L. P., Willerslev, E., Sicheritz-Pontén, T., Lund, O., Hansen, A. J., Izarzugaza, J. M. G. & 1 others, Brunak, Søren, 2016, In: Viruses. 8, 2, 16 p., 53.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    In Silico Systems Pharmacology to Assess Drug's Therapeutic and Toxic Effects

    Orozco, A. A., Audouze, K., Brunak, Søren & Taboureau, O., 2016, In: Current Pharmaceutical Design. 22, 46, p. 6895-6902 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study

    Folkersen, L., Brynedal, B., Diaz-Gallo, L. M., Ramsköld, D., Shchetynsky, K., Westerlind, H., Sundström, Y., Schepis, D., Hensvold, A., Vivar, N., Eloranta, M., Rönnblom, L., Brunak, Søren, Malmström, V., Catrina, A. I., Mørch, U. G., Klareskog, L., Padyukov, L. & Berg, L., 2016, In: Molecular medicine (Cambridge, Mass.). 22, p. 3223328

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Propionibacterium acnes: disease-causing agent or common contaminant? Detection in diverse patient samples by next-generation sequencing

    Mollerup, S., Friis-Nielsen, J., Vinner, Lasse, Hansen, T. A., Richter, S. R., Fridholm, E. M. H., Herrera, J. A. R., Lund, O., Brunak, Søren, Izarzugaza, J. M. G., Mourier, T., Nielsen, L. P. & Hansen, Anders Johannes, 2016, In: Journal of Clinical Microbiology. 54, 4, p. 980-987 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Ranking factors involved in diabetes remission after bariatric surgery using machine-learning integrating clinical and genomic biomarkers

    Pedersen, H. K., Gudmundsdottir, V., Pedersen, M. K., Brorsson, C., Brunak, Søren & Gupta, R., 2016, In: npj Genomic Medicine. 1, 16035.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    TEMPORAL ORDER OF DISEASE PAIRS AFFECTS SUBSEQUENT DISEASE TRAJECTORIES: THE CASE OF DIABETES AND SLEEP APNEA

    Beck, M. K., Westergaard, David, Jensen, A. B., Groop, L. & Brunak, Søren, 2016, In: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 22, p. 380-389 10 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  46. Published

    Tools and data services registry: a community effort to document bioinformatics resources

    Ison, J., Rapacki, K., Ménager, H., Kalaš, M., Rydza, E., Chmura, P., Anthon, C., Beard, N., Berka, K., Bolser, D., Booth, T., Bretaudeau, A., Brezovsky, J., Casadio, R., Cesareni, G., Coppens, F., Cornell, M., Cuccuru, G., Davidsen, K., Vedova, G. D. & 49 others, Dogan, T., Doppelt-Azeroual, O., Emery, L., Gasteiger, E., Gatter, T., Goldberg, T., Grosjean, M., Grüning, B., Helmer-Citterich, M., Ienasescu, H., Ioannidis, V., Jespersen, M. C., Jimenez, R., Juty, N., Juvan, P., Koch, M., Laibe, C., Li, J., Licata, L., Mareuil, F., Mičetić, I., Friborg, R. M., Moretti, S., Morris, C., Möller, S., Nenadic, A., Peterson, H., Profiti, G., Rice, P., Romano, P., Roncaglia, P., Saidi, R., Schafferhans, A., Schwämmle, V., Smith, C., Sperotto, M. M., Stockinger, H., Vařeková, R. S., Tosatto, S. C. E., de la Torre, V., Uva, P., Via, A., Yachdav, G., Zambelli, F., Vriend, G., Rost, B., Parkinson, H., Løngreen, P. & Brunak, Søren, 2016, In: Nucleic Acids Research. 44, D1, p. D38-D47 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2015
  48. Published

    Long-term risk of cardiovascular and cerebrovascular disease after removal of the colonic microbiota by colectomy: a cohort study based on the Danish National Patient Register from 1996 to 2014

    Jensen, A. B., Ajslev, T. A., Brunak, Søren & Sørensen, Thorkild I.A., 15 Dec 2015, In: B M J Open. 5, 8 p., e008702.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death

    Rondas, D., Gudmundsdottir, V., D'Hertog, W., Crèvecoeur, I., Waelkens, E., Brunak, Søren, Mathieu, C. & Overbergh, L., Oct 2015, In: Proteomics - Clinical Applications. 9, 9-10, p. 938–952 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics

    Rasmussen, Henrik Berg, Bjerre, D., Linnet, Kristian, Jürgens, G., Dalhoff, Kim, Stefansson, H., Hankemeier, T., Kaddurah-Daouk, R., Taboureau, O., Brunak, Søren, Houmann, T., Jeppesen, Pia, Pagsberg, Anne Katrine, Plessen, K., Dyrborg, J., Hansen, Peter Riis, Hansen, P. E., Hughes, T., Werge, Thomas & INDICES Consortium, I. C., Apr 2015, In: Pharmacogenomics. 16, 6, p. 649-65

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, Dore, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Dusko Ehrlich, S., Bork, P. & Pedersen, Oluf Borbye, 2015, In: Nature. 528, 7581, p. 262-266 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Early divergent strains of Yersinia pestis in Eurasia 5,000 years ago

    Rasmussen, S., Allentoft, M. E., Nielsen, K., Orlando, L. A. A., Sikora, M., Sjögren, K-G., Pedersen, A. G., Schubert, M., Van Dam, A., Kapel, C. M. O., Nielsen, H. B., Brunak, S., Avetisyan, P., Epimakhov, A., Khalyapin, M. V., Gnuni, A., Kriiska, A., Lasak, I., Metspalu, M., Moiseyev, V. & 11 others, Gromov, A., Pokutta, D., Saag, L., Varul, L., Yepiskoposyan, L., Sicheritz-Ponten, T., Foley, R. A., Lahr, M. M., Nielsen, R., Kristiansen, K. & Willerslev, Eske, 2015, In: Cell. 163, 3, p. 571-582 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Investigation of human cancers for retrovirus by low-stringency target enrichment and high-throughput sequencing

    Vinner, Lasse, Mourier, T., Friis-Nielsen, J., Gniadecki, R., Dybkaer, K., Rosenberg, J., Langhoff, J. L., Flores Santa Cruz, D., Fonager, J., Izarzugaza, J. M. G., Gupta, R., Sicheritz-Ponten, T., Brunak, Søren, Willerslev, Eske, Nielsen, L. P. & Hansen, Anders Johannes, 2015, In: Scientific Reports. 5, 13 p., 13201.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios

    Besenbacher, S., Liu, S., Gonzalez-Izarzugaza, J. M., Grove, J., Belling, K. G., Bork-Jensen, J., Huang, S., Als, T. D., Li, S., Yadav, R., Rubio García, A., Lescai, F., Demontis, D., Rao, J., Ye, W., Mailund, T., Møllegaard Friborg, R., Pedersen, C. N. S., Xu, R., Sun, J. & 27 others, Liu, H., Wang, O., Cheng, X., Flores, D., Rydza, E. K., Rapacki, K., Sørensen, J. D., Chmura, P. J., Westergaard, David, Dworzynski, P., Sørensen, Thorkild I.A., Lund, O., Hansen, Torben, Xu, X., Li, N., Bolund, L., Pedersen, Oluf Borbye, Eiberg, Hans Rudolf Lytchoff, Krogh, Anders, Børglum, A. D., Brunak, Søren, Kristiansen, Karsten, Schierup, M. H., Wang, J., Gupta, R., Villesen, P. & Rasmussen, Simon, 2015, In: Nature Communications. 6, 9 p., 5969.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 12895347