Niels Skotte

Niels Skotte

Assistant Professor, Visiting professor


  1. Published

    p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin

    Ehrnhoefer, D. E., Skotte, Niels Henning, Ladha, S., Nguyen, Y. T. N., Qiu, X., Deng, Y., Huynh, K. T., Engemann, S., Nielsen, S. M., Becanovic, K., Leavitt, B. R., Hasholt, Lis Frydenreich & Hayden, M. R., 1 Feb 2014, In: Human Molecular Genetics. 23, 3, p. 717-29 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Site-specific characterization of endogenous SUMOylation across species and organs

    Hendriks, Ivo Alexander, Lyon, D., Su, D., Skotte, Niels Henning, Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Nature Communications. 9, p. 1-17 2456.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice

    Uribe, V., Wong, B. K. Y., Graham, R. K., Cusack, C. L., Skotte, N. H., Pouladi, M. A., Xie, Y., Feinberg, K., Ou, Y., Ouyang, Y., Deng, Y., Franciosi, S., Bissada, N., Spreeuw, A., Zhang, W., Ehrnhoefer, D. E., Vaid, K., Miller, F. D., Deshmukh, M., Howland, D. & 1 others, Hayden, M. R., 1 May 2012, In: Human Molecular Genetics. 21, 9, p. 1954-67 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Reduced gluconeogenesis and lactate clearance in Huntington's disease

    Josefsen, K., Nielsen, S. M. B., Campos, A., Seifert, T., Hasholt, Lis Frydenreich, Nielsen, Jørgen Erik, Nørremølle, Anne, Skotte, Niels Henning, Secher, Niels H. & Quistorff, B., 1 Dec 2010, In: Neurobiology of Disease. 40, 3, p. 656-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

    Østergaard, M. E., Southwell, A. L., Kordasiewicz, H., Watt, A. T., Skotte, Niels Henning, Doty, C. N., Vaid, K., Villanueva, Erika Bianca, Swayze, E. E., Bennett, C. F., Hayden, M. R. & Seth, P. P., Nov 2013, In: Nucleic Acids Research. 41, 21, p. 9634-50 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Progressive Mitochondrial Dysfunction of Striatal Synapses in R6/2 Mouse Model of Huntington's Disease

    Petersen, M. H., Willert, C. W., Andersen, Jens Velde, Madsen, M., Waagepetersen, Helle S., Skotte, Niels Henning & Nørremølle, Anne, 2022, In: Journal of Huntington's disease. 11, 2, p. 121-140

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin

    Carroll, J. B., Warby, S. C., Southwell, A. L., Doty, C. N., Greenlee, S., Skotte, Niels Henning, Hung, G., Bennett, C. F., Freier, S. M. & Hayden, M. R., Dec 2011, In: Molecular therapy : the journal of the American Society of Gene Therapy. 19, 12, p. 2178-85 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Polycystin-1: a key player in hereditary cystic kidney and liver disorders

    Skotte, Niels Henning, Dec 2011, In: Clinical Genetics. 80, 6, p. 507-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Personalized gene silencing therapeutics for Huntington disease

    Kay, C., Skotte, Niels Henning, Southwell, A. L. & Hayden, M. R., Jul 2014, In: Clinical Genetics. 86, 1, p. 29-36 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Palmitoylation of caspase-6 by HIP14 regulates its activation

    Skotte, Niels Henning, Sanders, S. S., Singaraja, R. R., Ehrnhoefer, D. E., Vaid, K., Qiu, X., Kannan, S., Verma, C. & Hayden, M. R., 2017, In: Cell Death and Differentiation. 24, p. 433-444 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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