Niels Skotte

Niels Skotte

Assistant professor

  • Mann Group

    Blegdamsvej 3, 2200 København N, Bygning 6, Building: 06-6-38

    Phone: +45 35 33 22 34

  1. 2020
  2. Published

    Compromised IGF signaling causes caspase-6 activation in Huntington disease

    Skotte, Niels Henning, Pouladi, M. A., Ehrnhoefer, D. E., Huynh, K., Qiu, X., Nielsen, S. M. B., Nielsen, T. T., Nørremølle, Anne & Hayden, M. R., 2020, In : Experimental Neurology. 332, 113396.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome

    Utami, K. H., Skotte, Niels Henning, Colaço, A. R., Yusof, N. A. B. M., Sim, B., Yeo, X. Y., Bae, H., Garcia-Miralles, M., Radulescu, C. I., Chen, Q., Chaldaiopoulou, G., Liany, H., Nama, S., Peteri, U. A., Sampath, P., Castrén, M. L., Jung, S., Mann, Matthias & Pouladi, M. A., 2020, In : Biological Psychiatry. 88, 6, p. 500-511

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2019
  5. Published

    Functional Differences between Synaptic Mitochondria from the Striatum and the Cerebral Cortex

    Petersen, M. H., Willert, C. W., Andersen, Jens Velde, Waagepetersen, Helle S., Skotte, Niels Henning & Nørremølle, Anne, May 2019, In : Neuroscience. 406, p. 432-443 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound

    Ehrnhoefer, D. E., Skotte, Niels Henning, Reinshagen, J., Qiu, X., Windshuegel, B., Jaishankar, P., Ladha, S., Petina, O., Khankischpur, M., Nguyen, Y. T. N., Caron, N. S., Razeto, A., Zu Rheda, M. M., Deng, Y., Huynh, K. T., Wittig, I., Gribbon, P., Renslo, A. R., Geffken, D., Gul, S. & Hayden, M. R., 2019, In : Cell Chemical Biology. 26, 9, p. 1295-1305.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Aldana Garcia, Blanca Irene, Nørremølle, Anne & Waagepetersen, Helle S., 2019, In : Cellular and Molecular Life Sciences. 76, 12, p. 2449-2461

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2018
  9. Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease

    Southwell, A. L., Kordasiewicz, H. B., Langbehn, D., Skotte, Niels Henning, Parsons, M. P., Villanueva, Erika Bianca, Caron, N. S., Østergaard, M. E., Anderson, L. M., Xie, Y., Cengio, L. D., Findlay-Black, H., Doty, C. N., Fitsimmons, B., Swayze, E. E., Seth, P. P., Raymond, L. A., Frank Bennett, C. & Hayden, M. R., 2018, In : Science Translational Medicine. 10, 461, p. 1-12 eaar3959.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Site-specific characterization of endogenous SUMOylation across species and organs

    Hendriks, Ivo Alexander, Lyon, D., Su, D., Skotte, Niels Henning, Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In : Nature Communications. 9, p. 1-17 2456.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2017
  13. Published

    A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles

    Southwell, A. L., Skotte, Niels Henning, Villanueva, Erika Bianca, Østergaard, M. E., Gu, X., Kordasiewicz, H. B., Kay, C., Cheung, D., Xie, Y., Waltl, S., Dal Cengio, L., Findlay-Black, H., Doty, C. N., Petoukhov, E., Iworima, D., Slama, R., Ooi, J., Pouladi, M. A., Yang, X. W., Swayze, E. E., Seth, P. P. & Hayden, M. R., 15 Mar 2017, In : Human Molecular Genetics. 26, 6, p. 1115-1132 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Palmitoylation of caspase-6 by HIP14 regulates its activation

    Skotte, Niels Henning, Sanders, S. S., Singaraja, R. R., Ehrnhoefer, D. E., Vaid, K., Qiu, X., Kannan, S., Verma, C. & Hayden, M. R., 2017, In : Cell Death and Differentiation. 24, p. 433-444 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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