Niels Mailand

Niels Mailand

Professor, head of research, Professor


  1. 2009
  2. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

    Doil, C., Mailand, Niels, Bekker-Jensen, Simon Holst, Ménard, Patrice, Larsen, D. H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 2009, In: Cell. 136, 3, p. 435-46 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin

    Faustrup, H., Bekker-Jensen, Simon Holst, Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 184, 1, p. 13-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2008
  5. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

    Melander, F., Bekker-Jensen, Simon Holst, Falck, J., Bartek, J., Mailand, Niels & Lukas, Jiri, 21 Apr 2008, In: Journal of Cell Biology. 181, 2, p. 213-26 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2007
  7. Published

    Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks

    Bekker-Jensen, Simon Holst, Fugger, K., Danielsen, J. R., Gromova, I., Sehested, M., Celis, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 6 Jul 2007, In: Journal of Biological Chemistry. 282, 27, p. 19638-43 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

    Mailand, Niels, Bekker-Jensen, Simon Holst, Faustrup, H., Melander, F., Bartek, J., Lukas, Claudia & Lukas, Jiri, 2007, In: Cell. 131, 5, p. 887-900 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2006
  10. TOPping up ATR activity

    Bartek, J. & Mailand, Niels, 10 Mar 2006, In: Cell. 124, 5, p. 888-90 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  11. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

    Liu, S., Bekker-Jensen, Simon Holst, Mailand, Niels, Lukas, Claudia, Bartek, J. & Lukas, Jiri, 2006, In: Molecular and Cellular Biology. 26, 16, p. 6056-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress

    Mailand, Niels, Bekker-Jensen, Simon Holst, Bartek, J. & Lukas, Jiri, 2006, In: Molecular Cell. 23, 3, p. 307-18 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. The replication kinase Cdc7-Dbf4 promotes the interaction of the p150 subunit of chromatin assembly factor 1 with proliferating cell nuclear antigen

    Gérard, A., Koundrioukoff, S., Ramillon, V., Sergère, J., Mailand, Niels, Quivy, J. & Almouzni, G., 2006, In: E M B O Reports. 7, 8, p. 817-23 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2005
  15. CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

    Mailand, Niels & Diffley, J. F. X., 23 Sep 2005, In: Cell. 122, 6, p. 915-26 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2004
  17. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

    Krämer, A., Mailand, Niels, Lukas, Claudia, Syljuåsen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. & Lukas, Jiri, Sep 2004, In: Nature Cell Biology. 6, 9, p. 884-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2002
  19. Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

    Mailand, Niels, Lukas, Claudia, Kaiser, B. K., Jackson, P. K., Bartek, J. & Lukas, Jiri, Apr 2002, In: Nature Cell Biology. 4, 4, p. 317-22 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability.

    Mailand, Niels, Podtelejnikov, A. V., Groth, Anja, Mann, M., Bartek, J. & Lukas, Jiri, 2002, In: EMBO Journal. 21, 21, p. 5911-20 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2001
  22. DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology

    Lukas, Claudia, Bartkova, J., Latella, L., Falck, J., Mailand, Niels, Schroeder, T., Sehested, M., Lukas, Jiri & Bartek, J., 1 Jul 2001, In: Cancer Research. 61, 13, p. 4990-3 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

    Falck, J., Mailand, Niels, Syljuåsen, R. G., Bartek, J. & Lukas, Jiri, 12 Apr 2001, In: Nature. 410, 6830, p. 842-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2000
  25. Rapid destruction of human Cdc25A in response to DNA damage

    Mailand, Niels, Falck, J., Lukas, Claudia, Syljuåsen, R. G., Welcker, M., Bartek, J. & Lukas, Jiri, 26 May 2000, In: Science (New York, N.Y.). 288, 5470, p. 1425-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

    Santoni Rugiu, Eric, Falck, J., Mailand, Niels, Bartek, J. & Lukas, Jiri, May 2000, In: Molecular and Cellular Biology. 20, 10, p. 3497-509 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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