Nicolai Jacob Wewer Albrechtsen

Nicolai Jacob Wewer Albrechtsen

Associate Professor


  1. 2020
  2. Published

    The GLP-1 receptor agonist lixisenatide reduces postprandial glucose in patients with diabetes secondary to total pancreatectomy: a randomised, placebo-controlled, double-blinded crossover trial

    Juel, C. T. B., Lund, A., Andersen, M. M., Hansen, C. P., Storkholm, J. H., Rehfeld, Jens Frederik, van Hall, G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2020, In: Diabetologia. 63, p. 1285-1298

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

    Batista, T. M., Jayavelu, A. K., Albrechtsen, Nicolai Jacob Wewer, Iovino, S., Lebastchi, J., Pan, H., Dreyfuss, J. M., Krook, A., Zierath, Juleen R, Mann, Matthias & Kahn, C. R., 2020, In: Cell Metabolism. 32, 5, p. 844-859.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A Potential Role for Endogenous Glucagon in Preventing Post-Bariatric Hypoglycemia

    Lobato, C. B., Pereira, S. S., Guimaraes, M., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Frontiers in Endocrinology. 11, 11 p., 608248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Alanine, arginine, cysteine, and proline, but not glutamine, are substrates for, and acute mediators of, the liver-α-cell axis in female mice

    Galsgaard, Katrine Douglas, Jepsen, Sara Lind, Kjeldsen, Sasha Alexandra Sampson, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E920-E929 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy

    Eiken, A., Fuglsang, S., Eiken, M., Svane, M. S., Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hansen, S. H., Trammell, Sam, Svenningsen, J. S., Rehfeld, Jens Frederik, Bojsen-Møller, K. N., Jørgensen, N. B., Holst, Jens Juul, Madsbad, Sten, Madsen, J. L. & Dirkse, C., 2020, In: International Journal of Obesity. 44, p. 1872-1883

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Cholesteryl ester storage disease of clinical and genetic characterisation: A case report and review of literature

    Rashu, E. B., Junker, A. E., Danielsen, K. V., Dahl, E., Hamberg, O., Borgwardt, L., Christensen, Vibeke Brix, Albrechtsen, Nicolai Jacob Wewer & Gluud, Lise Lotte, 2020, In: World Journal of Clinical Cases. 8, 9, p. 1642-1650

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Different Malabsorptive Obesity Surgery Interventions Result in Distinct Postprandial Amino Acid Metabolomic Signatures

    Pereira, S. S., Jarak, I., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimaraes, M., Almeida, R., Pereira, A. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, p. 4019-4028

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effects of a six-week intervention with glucagon-like peptide-1 receptor analogue on pancreatic volume, oedema and DNA synthesis in obese men

    Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, A. E., Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S216-S217 442.

    Research output: Contribution to journalConference abstract in journalResearch

  10. Published

    Effects of an intensive lifestyle intervention on the underlying mechanisms of improved glycaemic control in individuals with type 2 diabetes: a secondary analysis of a randomised clinical trial

    Johansen, M. Y., Karstoft, K., MacDonald, C. S., Hansen, K. B., Ellingsgaard, H., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Vaag, A. A., Holst, Jens Juul, Pedersen, Bente Klarlund & Ried-Larsen, M., 2020, In: Diabetologia. 63, p. 2410-2422 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Efficacy and safety of meal-time administration of short-acting exenatide for glycaemic control in type 1 diabetes (MAG1C): a randomised, double-blind, placebo-controlled trial

    Johansen, N. J., Dejgaard, T. F., Lund, A., Schluntz, C., Frandsen, C. S., Forman, Julie Lyng, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Madsbad, Sten, Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2020, In: The Lancet Diabetes & Endocrinology. 8, 4, p. 313-324 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    GLP-1 secretion is regulated by IL-6 signalling: a randomised, placebo-controlled study

    Ellingsgaard, H., Seelig, E., Timper, K., Coslovsky, M., Soederlund, L., Lyngbaek, M. P., Albrechtsen, Nicolai Jacob Wewer, Schmidt-Trucksäss, A., Hanssen, H., Frey, W. O., Karstoft, K., Pedersen, Bente Klarlund, Böni-Schnetzler, M. & Donath, M. Y., 2020, In: Diabetologia. 63, 2, p. 362-373 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Gastric Bypass with Different Biliopancreatic Limb Lengths Results in Similar Post-absorptive Metabolomics Profiles

    Jarak, I., Pereira, S. S., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, 3, p. 1068-1078 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic Steatosis

    Suppli, M. P., Bagger, J. I., Lund, A., Demant, M., van Hall, Gerrit, Strandberg, C., Kønig, M. J., Rigbolt, K., Langhoff, J. L., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes. 69, 6, p. 1090-1099 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

    Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, Werge, M. P., Bisgaard, Hanne Cathrine, Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Molecular Metabolism. 42, 18 p., 101080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Glucagon promotes hepatic autophagy by AMPK-mediated mTORC1 inhibition

    Galsgaard, Katrine Douglas, Lee, J., Hubbard, B. T., Zhang, X. -., Cline, G. W., Nasiri, A. R., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Pertersen, K. F. & Shulman, G. I., 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S232

    Research output: Contribution to journalConference abstract in journalResearch

  17. Published

    Glucagon receptor signaling is not required for N-carbamoyl glutamate- And L-citrulline-induced ureagenesis in mice

    Galsgaard, Katrine Douglas, Pedersen, Jens, Kjeldsen, Sasha Alexandra Sampson, Winther-Sørensen, Marie, Stojanovska, E., Vilstrup, H., Ørskov, Cathrine, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 5, p. G912-G927

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Glucagon-Like Peptide 2 Inhibits Postprandial Gallbladder Emptying in Man: A Randomized, Double-Blinded, Crossover Study

    Hansen, N. L., Brønden, Andreas, Nexoe-Larsen, C. C., Christensen, A. S., Sonne, D. P., Rehfeld, Jens Frederik, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2020, In: Clinical and Translational Gastroenterology. 11, 12, 9 p., e00257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Hepatic steatosis and glucagon resistance develope in parallel resulting in hyperglucagonaemia and hyperaminoacidaemia

    Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Santos, A., Pedersen, J., Hassing, Anna Skab, Dall, M., Treebak, Jonas Thue, Kjeldsen, Sasha Alexandra Sampson, Knop, Filip Krag, Werge, M. P., Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S71-S72 142.

    Research output: Contribution to journalConference abstract in journalResearch

  20. Published

    Interleukin-6 May Not Affect Bone Resorption Marker CTX or Bone Formation Marker P1NP in Humans

    Lehrskov, L. L., Kjeldsen, Sasha Alexandra Sampson, Lyngbæk, M. P., Chirstensen, R. H., Wedell-Neergaard, A., Søderlund, L., Jørgensen, Niklas Rye, Krogh-Madsen, Rikke, Albrechtsen, Nicolai Jacob Wewer & Ellingsgaard, H., 2020, In: Endocrine Research. 4, 9, 12 p., bvaa093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Neprilysin inhibition increases plasma glucagon concentrations in humans with possible implications for hepatic amino acid metabolism

    Liver-Alpha-Cell Axis Grp, L. A. G., 2020, In: Diabetologia. 63, SUPPL 1, p. S72-S72 1 p., 144.

    Research output: Contribution to journalConference abstract in journalResearch

  22. Published

    No effects of a 6-week intervention with a glucagon-like peptide-1 receptor agonist on pancreatic volume and oedema in obese men without diabetes

    Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, Adam Espe, Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Klausen, T. L., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetes, Obesity and Metabolism. 22, 10, p. 1837-1846

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Nonalcoholic Fatty Liver Disease Impairs the Liver-Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis

    Pedersen, J. S., Rygg, M. O., Kristiansen, V. B., Olsen, B. H., Serizawa, R. R., Holst, Jens Juul, Madsbad, Sten, Gluud, Lise Lotte, Bendtsen, Flemming & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Hepatology Communications. 4, 11, p. 1610-1623 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Oxyntomodulin and glicentin may predict the effect of bariatric surgery on food preferences and weight loss

    Nielsen, M. S., Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, le Roux, C. W. & Sjödin, Anders Mikael, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 4, p. e1064-e1074

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice

    Sachs, S., Niu, Lili, Geyer, P., Jall, S., Kleinert, Maximilian, Feuchtinger, A., Stemmer, K., Brielmeier, M., Finan, B., DiMarchi, R. D., Tschop, M. H., Albrechtsen, Nicolai Jacob Wewer, Mann, Matthias, Mueller, T. D. & Hofmann, S. M., 2020, In: Diabetes, Obesity and Metabolism. 23, 1, p. 195-207 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Predictors of weight loss after bariatric surgery - a cross-disciplinary approach combining physiological, social, and psychological measures

    Nielsen, M. S., Christensen, Bodil Just, Schmidt, J. B., Tækker, L., Holm, Lotte, Lunn, Susanne, Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Schnurr, T. M., Hansen, Torben, le Roux, C. W., Lund, Thomas Bøker, Floyd, A. K. & Sjödin, Anders Mikael, 2020, In: International Journal of Obesity. 44, 11, p. 2291-2302 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 95638859