Nicolai Jacob Wewer Albrechtsen

Nicolai Jacob Wewer Albrechtsen

Associate Professor


  1. 2020
  2. Published

    GLP-1 secretion is regulated by IL-6 signalling: a randomised, placebo-controlled study

    Ellingsgaard, H., Seelig, E., Timper, K., Coslovsky, M., Soederlund, L., Lyngbaek, M. P., Albrechtsen, Nicolai Jacob Wewer, Schmidt-Trucksäss, A., Hanssen, H., Frey, W. O., Karstoft, K., Pedersen, Bente Klarlund, Böni-Schnetzler, M. & Donath, M. Y., 2020, In: Diabetologia. 63, 2, p. 362-373 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Gastric Bypass with Different Biliopancreatic Limb Lengths Results in Similar Post-absorptive Metabolomics Profiles

    Jarak, I., Pereira, S. S., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, 3, p. 1068-1078 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic Steatosis

    Suppli, M. P., Bagger, J. I., Lund, A., Demant, M., van Hall, Gerrit, Strandberg, C., Kønig, M. J., Rigbolt, K., Langhoff, J. L., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes. 69, 6, p. 1090-1099 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

    Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, Werge, M. P., Bisgaard, Hanne Cathrine, Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Molecular Metabolism. 42, 18 p., 101080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Glucagon promotes hepatic autophagy by AMPK-mediated mTORC1 inhibition

    Galsgaard, Katrine Douglas, Lee, J., Hubbard, B. T., Zhang, X. -., Cline, G. W., Nasiri, A. R., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Pertersen, K. F. & Shulman, G. I., 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S232

    Research output: Contribution to journalConference abstract in journalResearch

  7. Published

    Glucagon receptor signaling is not required for N-carbamoyl glutamate- And L-citrulline-induced ureagenesis in mice

    Galsgaard, Katrine Douglas, Pedersen, Jens, Kjeldsen, Sasha Alexandra Sampson, Winther-Sørensen, Marie, Stojanovska, E., Vilstrup, H., Ørskov, Cathrine, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 5, p. G912-G927

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Glucagon-Like Peptide 2 Inhibits Postprandial Gallbladder Emptying in Man: A Randomized, Double-Blinded, Crossover Study

    Hansen, N. L., Brønden, Andreas, Nexoe-Larsen, C. C., Christensen, A. S., Sonne, D. P., Rehfeld, Jens Frederik, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2020, In: Clinical and Translational Gastroenterology. 11, 12, 9 p., e00257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Hepatic steatosis and glucagon resistance develope in parallel resulting in hyperglucagonaemia and hyperaminoacidaemia

    Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Santos, A., Pedersen, J., Hassing, Anna Skab, Dall, M., Treebak, Jonas Thue, Kjeldsen, Sasha Alexandra Sampson, Knop, Filip Krag, Werge, M. P., Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S71-S72 142.

    Research output: Contribution to journalConference abstract in journalResearch

  10. Published

    Interleukin-6 May Not Affect Bone Resorption Marker CTX or Bone Formation Marker P1NP in Humans

    Lehrskov, L. L., Kjeldsen, Sasha Alexandra Sampson, Lyngbæk, M. P., Chirstensen, R. H., Wedell-Neergaard, A., Søderlund, L., Jørgensen, Niklas Rye, Krogh-Madsen, Rikke, Albrechtsen, Nicolai Jacob Wewer & Ellingsgaard, H., 2020, In: Endocrine Research. 4, 9, 12 p., bvaa093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Neprilysin inhibition increases plasma glucagon concentrations in humans with possible implications for hepatic amino acid metabolism

    Liver-Alpha-Cell Axis Grp, L. A. G., 2020, In: Diabetologia. 63, SUPPL 1, p. S72-S72 1 p., 144.

    Research output: Contribution to journalConference abstract in journalResearch

  12. Published

    No effects of a 6-week intervention with a glucagon-like peptide-1 receptor agonist on pancreatic volume and oedema in obese men without diabetes

    Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, Adam Espe, Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Klausen, T. L., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetes, Obesity and Metabolism. 22, 10, p. 1837-1846

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Nonalcoholic Fatty Liver Disease Impairs the Liver-Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis

    Pedersen, J. S., Rygg, M. O., Kristiansen, V. B., Olsen, B. H., Serizawa, R. R., Holst, Jens Juul, Madsbad, Sten, Gluud, Lise Lotte, Bendtsen, Flemming & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Hepatology Communications. 4, 11, p. 1610-1623 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Oxyntomodulin and glicentin may predict the effect of bariatric surgery on food preferences and weight loss

    Nielsen, M. S., Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, le Roux, C. W. & Sjödin, Anders Mikael, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 4, p. e1064-e1074

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice

    Sachs, S., Niu, Lili, Geyer, P., Jall, S., Kleinert, Maximilian, Feuchtinger, A., Stemmer, K., Brielmeier, M., Finan, B., DiMarchi, R. D., Tschop, M. H., Albrechtsen, Nicolai Jacob Wewer, Mann, Matthias, Mueller, T. D. & Hofmann, S. M., 2020, In: Diabetes, Obesity and Metabolism. 23, 1, p. 195-207 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Predictors of weight loss after bariatric surgery - a cross-disciplinary approach combining physiological, social, and psychological measures

    Nielsen, M. S., Christensen, Bodil Just, Schmidt, J. B., Tækker, L., Holm, Lotte, Lunn, Susanne, Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Schnurr, T. M., Hansen, Torben, le Roux, C. W., Lund, Thomas Bøker, Floyd, A. K. & Sjödin, Anders Mikael, 2020, In: International Journal of Obesity. 44, 11, p. 2291-2302 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Proglucagon peptide secretion profiles in type 2 diabetes before and after bariatric surgery: 1-year prospective study

    Alexiadou, K., Cuenco, J., Howard, J., Albrechtsen, Nicolai Jacob Wewer, Ilesanmi, I., Kamocka, A., Tharakan, G., Behary, P., Bech, P. R., Ahmed, A. R., Purkayastha, S., Wheller, R., Fleuret, M., Holst, Jens Juul, Bloom, S. R., Khoo, B. & Tan, T. M. M., 2020, In: B M J Open Diabetes Research & Care. 8, 1, 10 p., e001076.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study

    Quist, Jonas Salling, Jensen, M. M., Clemmensen, K. K. B., Pedersen, H., Bjerre, N., Størling, Joachim, Blond, M. B., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G. & Faerch, K., 2020, In: BMJ Open. 10, 8, 11 p., 037166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery

    Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Kristiansen, V. B., Rehfeld, Jens Frederik, Clausen, T. R., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Sacubitril/valsartan increases postprandial gastrin and cholecystokinin in plasma

    Andersen, U. O., Terzic, D., Albrechtsen, Nicolai Jacob Wewer, Mark, P. D., Plomgaard, Peter Stendahl, Rehfeld, Jens Frederik, Gustafsson, Finn & Goetze, Jens P. , 2020, In: Endocrine Connections. 9, 5, p. 438-444

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

    Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Secretion of parathyroid hormone may be coupled to insulin secretion in humans

    Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery

    Martinussen, C., Veedfald, Simon, Dirksen, Carsten Moro, Bojsen-Møller, K. N., Svane, M. S., Albrechtsen, Nicolai Jacob Wewer, van Hall, Gerrit, Kristiansen, V. B., Fenger, M., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E956-E964 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2019
  25. Published

    Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease

    Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  26. Published

    FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism

    Sakaguchi, M., Cai, W., Wang, C., Cederquist, C. T., Damasio, M., Homan, E. P., Batista, T., Ramirez, A. K., Gupta, M. K., Steger, M., Albrechtsen, Nicolai Jacob Wewer, Singh, S. K., Araki, E., Mann, M., Enerbäck, S. & Kahn, C. R., 5 Apr 2019, In: Nature Communications. 10, 1, 17 p., 1582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents

    Christiansen, Charlotte Bayer, Trammell, Sam, Albrechtsen, Nicolai Jacob Wewer, Schoonjans, K., Albrechtsen, Reidar, Gillum, M. P., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G574-G584 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 95638859