Matthias Mann

Matthias Mann

Professor, head of research, Professor


  1. 2023
  2. Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis

    Nagao, H., Jayavelu, A. K., Cai, W., Pan, H., Dreyfuss, J. M., Batista, T. M., Brandão, B. B., Mann, Matthias & Kahn, C. R., 4 Jan 2023, In: Nature Communications. 14, 1, p. 57

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Standardized and Reproducible Workflow for Membrane Glass Slides in Routine Histology and Spatial Proteomics

    Nordmann, T. M., Schweizer, L., Metousis, A., Thielert, Marvin Christoffer, Rodriguez, E., Gjerdrum, Lise Mette Rahbek, Stadler, P., Bzorek, M., Mund, Andreas, Rosenberger, F. A. & Mann, Matthias, 2023, In: Molecular & cellular proteomics : MCP. 22, 10, 9 p., 100643.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A reversible state of hypometabolism in a human cellular model of sporadic Parkinson’s disease

    Schmidt, S., Stautner, C., Vu, D. T., Heinz, A., Regensburger, M., Karayel, O., Trümbach, D., Artati, A., Kaltenhäuser, S., Nassef, M. Z., Hembach, S., Steinert, L., Winner, B., Jürgen, W., Jastroch, M., Luecken, M. D., Theis, F. J., Westmeyer, G. G., Adamski, J., Mann, M. & 4 others, Hiller, K., Giesert, F., Vogt Weisenhorn, D. M. & Wurst, W., 2023, In: Nature Communications. 14, 1, 24 p., 7674.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases

    Bernhardt, A. M., Tiedt, S., Teupser, D., Dichgans, M., Meyer, B., Gempt, J., Kuhn, P. H., Simons, M., Palleis, C., Weidinger, E., Nübling, G., Holdt, L., Hönikl, L., Gasperi, C., Giesbertz, P., Müller, S. A., Breimann, S., Lichtenthaler, S. F., Kuster, B., Mann, M. & 8 others, Imhof, A., Barth, T., Hauck, S. M., Zetterberg, H., Otto, M., Weichert, W., Hemmer, B. & Levin, J., 2023, In: EBioMedicine. 89, 13 p., 104456.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Activity-based profiling of cullin–RING E3 networks by conformation-specific probes

    Henneberg, L. T., Singh, J., Duda, D. M., Baek, K., Yanishevski, D., Murray, P. J., Mann, Matthias, Sidhu, S. S. & Schulman, B. A., 2023, In: Nature Chemical Biology. 19, p. 1513-1523

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    AlphaPeptStats: an open-source Python package for automated and scalable statistical analysis of mass spectrometry-based proteomics

    Krismer, Elena, Bludau, I., Strauss, Maximilian & Mann, Matthias, 2023, In: Bioinformatics. 39, 8, 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory components

    Ugur, E., de la Porte, A., Qin, W., Bultmann, S., Ivanova, A., Drukker, M., Mann, Matthias, Wierer, M. & Leonhardt, H., 2023, In: Nucleic Acids Research. 51, 6, p. 2671-2690 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Consistency across multi-omics layers in a drug-perturbed gut microbial community

    Wuyts, S., Alves, R., Zimmermann-Kogadeeva, M., Nishijima, S., Blasche, S., Driessen, M., Geyer, P. E., Hercog, R., Kartal, E., Maier, L., Müller, J. B., Garcia Santamarina, S., Schmidt, T. S. B., Sevin, D. C., Telzerow, A., Treit, P. V., Wenzel, T., Typas, A., Patil, K. R., Mann, M. & 2 others, Kuhn, M. & Bork, P., 2023, In: Molecular Systems Biology. 19, 9, 17 p., e11525.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

    Salehi, S., Zare, A., Prezza, G., Bader, J., Schneider, C., Fischer, U., Meissner, F., Mann, Matthias, Briese, M. & Sendtner, M., 2023, In: Nature Communications. 14, 19 p., 4158.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Democratizing knowledge representation with BioCypher

    Lobentanzer, S., Aloy, P., Baumbach, J., Bohar, B., Carey, V. J., Charoentong, P., Danhauser, K., Doğan, T., Dreo, J., Dunham, I., Farr, E., Fernandez-Torras, A., Gyori, B. M., Hartung, M., Hoyt, C. T., Klein, C., Korcsmaros, T., Maier, A., Mann, M., Ochoa, D. & 12 others, Pareja-Lorente, E., Popp, F., Preusse, M., Probul, N., Schwikowski, B., Sen, B., Strauss, Maximilian, Turei, D., Ulusoy, E., Waltemath, D., Wodke, J. A. H. & Saez-Rodriguez, J., 2023, In: Nature Biotechnology. 41, p. 1056-1059

    Research output: Contribution to journalLetterResearchpeer-review

  12. Published

    Foresight in clinical proteomics: current status, ethical considerations, and future perspectives

    Mundt Madsen, Filip Oskar, Albrechtsen, Nicolai Jacob Wewer, Porsdam Mann, Sebastian, Treit, P., Ghodgaonkar-Steger, M., O’Flaherty, M., Raijmakers, R., Vizcaíno, J. A., Heck, A. J. R. & Mann, Matthias, 2023, In: Open Research Europe. 3, 19 p., 59.

    Research output: Contribution to journalLetterResearchpeer-review

  13. Published

    Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling

    Nagao, H., Cai, W., Brandão, B. B., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Gattu, A. K., Pan, H., Dreyfuss, J. M., Thomas Wunderlich, F., Mann, Matthias & Ronald Kahn, C., 2023, In: Journal of Clinical Investigation. 133, 4, 18 p., e161472.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    MS-Based Proteomics of Body Fluids: The End of the Beginning

    Bader, J. M., Albrecht, V. & Mann, Matthias, 2023, In: Molecular and Cellular Proteomics. 22, 7, 18 p., 100577.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Making single-cell proteomics biologically relevant

    Rosenberger, F. A., Thielert, Marvin Christoffer & Mann, Matthias, 2023, In: Nature Methods. 20, p. 320-323 4 p.

    Research output: Contribution to journalComment/debateResearch

  16. Published

    Plasma proteome profiling of healthy subjects undergoing bed rest reveals unloading-dependent changes linked to muscle atrophy

    Murgia, M., Brocca, L., Monti, E., Franchi, M. V., Zwiebel, M., Steigerwald, S., Giacomello, E., Sartori, R., Zampieri, S., Capovilla, G., Gasparini, M., Biolo, G., Sandri, M., Mann, Matthias & Narici, M. V., 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, p. 439-451

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia

    Bech, J. M., Terkelsen, Thilde Bagger, Bartels, Annette Snejbjerg, Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G. I., Fang, X., Mann, Matthias & Moreira, José, 2023, In: Gastroenterology. 165, 1, p. 121-132.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status

    Bader, J. M., Deigendesch, N., Misch, M., Mann, Matthias, Koch, A. & Meissner, F., 2023, In: Cell Reports Medicine. 4, 1, 100877.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel

    Thielert, M., Itang, E. C. M., Ammar, C., Rosenberger, F. A., Bludau, I., Schweizer, L., Nordmann, T. M., Skowronek, P., Wahle, M., Zeng, W. F., Zhou, X. X., Brunner, A. D., Richter, S., Levesque, M. P., Theis, F. J., Steger, M. & Mann, Matthias, 2023, In: Molecular Systems Biology. 19, 9, 23 p., e11503.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome

    Rosenberger, F. A., Thielert, Marvin Christoffer, Strauss, Maximilian, Schweizer, L., Ammar, C., Mädler, S. C., Metousis, A., Skowronek, P., Wahle, M., Madden, K., Gote-Schniering, J., Semenova, A., Schiller, H. B., Rodriguez, E., Nordmann, T. M., Mund, Andreas & Mann, Matthias, 2023, In: Nature Methods. 20, 10, p. 1530-1536 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Synchro-PASEF allows precursor-specific fragment ion extraction and interference removal in data-independent acquisition

    Skowronek, P., Krohs, F., Lubeck, M., Wallmann, G., Itang, E. C. M., Koval, P., Wahle, M., Thielert, Marvin Christoffer, Meier, F., Willems, S., Raether, O. & Mann, Matthias, 2023, In: Molecular and Cellular Proteomics. 22, 2, 14 p., 100489.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The Proteome of Hand Eczema Assessed by Tape Stripping

    Sølberg, J. B. K., Quaade, A. S., Drici, L., Sulek, K., Ulrich, N. H., Løvendorf, Marianne Bengtson, Thyssen, Jacob Pontoppidan, Mann, Matthias, Dyring-Andersen, Beatrice & Johansen, Jeanne Duus, 2023, In: Journal of Investigative Dermatology. 143, p. 1559-1568

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The social and structural architecture of the yeast protein interactome

    Michaelis, A. C., Brunner, A., Zwiebel, M., Meier, F., Strauss, Maximilian, Bludau, I. & Mann, Matthias, 2023, In: Nature. 624, 7990, p. 192-200 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5650809