Matthias Mann

Matthias Mann

Professor, head of research, Professor

Member of:

    ORCID: 0000-0003-1292-4799

    Publication year:
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    1 - 25 out of 37Page size: 25
    1. 2022
    2. Published

      A knowledge graph to interpret clinical proteomics data

      Santos, A., Colaço, A. R., Nielsen, A. B., Niu, Lili, Strauss, Maximilian, Geyer, P. E., Coscia, F., Albrechtsen, Nicolai Jacob Wewer, Mundt, F., Jensen, Lars Juhl & Mann, Matthias, 2022, In: Nature Biotechnology. 40, p. 692–702

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      AlphaMap: an open-source Python package for the visual annotation of proteomics data with sequence-specific knowledge

      Voytik, E., Bludau, I., Willems, S., Hansen, F. M., Brunner, A., Strauss, Maximilian & Mann, Matthias, 2022, In: Bioinformatics. 38, 3, p. 849-852

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      AlphaPeptDeep: a modular deep learning framework to predict peptide properties for proteomics

      Zeng, W. F., Zhou, X. X., Willems, S., Ammar, C., Wahle, M., Bludau, I., Voytik, E., Strauss, Maximilian & Mann, Matthias, 2022, In: Nature Communications. 13, 14 p., 7238.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Association of Complement and MAPK Activation With SARS-CoV-2-Associated Myocardial Inflammation

      Weckbach, L. T., Schweizer, L., Kraechan, A., Bieber, S., Ishikawa-Ankerhold, H., Hausleiter, J., Massberg, S., Straub, T., Klingel, K., Grabmaier, U., Zwiebel, M., Mann, Matthias & Schulz, C., 2022, In: JAMA Cardiology. 7, 3, p. 286-297 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Cotranslational N-degron masking by acetylation promotes proteome stability in plants

      Linster, E., Forero Ruiz, F. L., Miklankova, P., Ruppert, T., Mueller, J., Armbruster, L., Gong, X., Serino, G., Mann, Matthias, Hell, R. & Wirtz, M., 2022, In: Nature Communications. 13, 1, p. 810

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation

      Qiao, S., Lee, C., Sherpa, D., Chrustowicz, J., Cheng, J., Duennebacke, M., Steigenberger, B., Karayel, O., Vu, D. T., von Gronau, S., Mann, Matthias, Wilfling, F. & Schulman, B. A., 2022, In: Nature Communications. 13, 3041.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      D13 Saliva biomarker discovery in Huntington’s disease

      Qvist, Filippa Liliendahl, Hellem, M. N., Nielsen, Jørgen Erik, Mann, Matthias & Skotte, Niels Henning, 2022, In: Journal of Neurology, Neurosurgery and Psychiatry. 93, Suppl. 1, p. A24-A25

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    9. Published

      Deep Visual Proteomics defines single-cell identity and heterogeneity

      Mund, A., Coscia, F., Kriston, A., Hollandi, R., Kovács, F., Brunner, A-D., Migh, E., Schweizer, L., Santos, A., Bzorek, M., Naimy, S., Rahbek-Gjerdrum, L. M., Dyring-Andersen, B., Bulkescher, J., Lukas, C., Eckert, M. A., Lengyel, E., Gnann, C., Lundberg, E., Horvath, P. & 1 others, Mann, Matthias, 2022, In: Nature Biotechnology. 40, p. 1231-1240

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Dynamic human liver proteome atlas reveals functional insights into disease pathways

      Niu, Lili, Geyer, P. E., Gupta, R., Santos, A., Meier, F., Doll, S., Albrechtsen, Nicolai Jacob Wewer, Klein, S., Ortiz, C., Uschner, F. E., Schierwagen, R., Trebicka, J. & Mann, Matthias, 2022, In: Molecular Systems Biology. 18, 5, 24 p., e10947.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons

      Riemenschneider, H., Guo, Q., Bader, J., Frottin, F., Farny, D., Kleinberger, G., Haass, C., Mann, Matthias, Hartl, F. U., Baumeister, W., Hipp, M. S., Meissner, F., Fernández-Busnadiego, R. & Edbauer, D., 2022, In: EMBO Reports. 23, 6, e53890.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      HYPK promotes the activity of the Nα-acetyltransferase A complex to determine proteostasis of nonAc-X2/N-degron-containing proteins

      Miklánková, P., Linster, E., Boyer, J., Weidenhausen, J., Mueller, J., Armbruster, L., Lapouge, K., De La Torre, C., Bienvenut, W., Sticht, C., Mann, Matthias, Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M., 2022, In: Science Advances. 8, 24, 14 p., eabn6153.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network

      Schmacke, N. A., O'Duill, F., Gaidt, M. M., Szymanska, I., Kamper, J. M., Schmid-Burgk, J. L., Mädler, S. C., Mackens-Kiani, T., Kozaki, T., Chauhan, D., Nagl, D., Stafford, C. A., Harz, H., Fröhlich, A. L., Pinci, F., Ginhoux, F., Beckmann, R., Mann, Matthias, Leonhardt, H. & Hornung, V., 2022, In: Immunity. 55, 12, p. 2271-2284.e7

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Identification of early neurodegenerative pathways in progressive multiple sclerosis

      Kaufmann, M., Schaupp, A. L., Sun, R., Coscia, F., Dendrou, C. A., Cortes, A., Kaur, G., Evans, H. G., Mollbrink, A., Navarro, J. F., Sonner, J. K., Mayer, C., DeLuca, G. C., Lundeberg, J., Matthews, P. M., Attfield, K. E., Friese, M. A., Mann, Matthias & Fugger, Lars, 2022, In: Nature Neuroscience. 25, p. 944-955

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance

      Wirth, A-K., Wange, L., Vosberg, S., Henrich, K-O., Rausch, C., Özdemir, E., Zeller, C. M., Richter, D., Feuchtinger, T., Kaller, M., Hermeking, H., Greif, P. A., Senft, D., Jurinovic, V., Bahrami, E., Jayavelu, A. K., Westermann, F., Mann, M., Enard, W., Herold, T. & 1 others, Jeremias, I., 2022, In: Leukemia. 36, p. 2863-2874 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Mast cells in lung damage of COVID-19 autopsies: A descriptive study

      Schaller, T., Märkl, B., Claus, R., Sholl, L., Hornick, J. L., Giannetti, M. P., Schweizer, L., Mann, Matthias & Castells, M., 2022, In: Allergy. 77, 7, p. 2237-2239 3 p.

      Research output: Contribution to journal › Comment/debate › Research

    17. Published

      Noninvasive proteomic biomarkers for alcohol-related liver disease

      Niu, Lili, Thiele, M., Geyer, P. E., Rasmussen, D. N., Webel, Henry, Santos, A., Gupta, R., Meier, F., Strauss, Maximilian, Kjaergaard, M., Lindvig, K., Jacobsen, S., Rasmussen, Simon, Hansen, Torben, Krag, A. & Mann, Matthias, 2022, In: Nature Medicine. 28, 6, p. 1277-1287 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      OpenCell: Endogenous tagging for the cartography of human cellular organization

      Cho, N. H., Cheveralls, K. C., Brunner, A. D., Kim, K., Michaelis, A. C., Raghavan, P., Kobayashi, H., Savy, L., Li, J. Y., Canaj, H., Kim, J. Y. S., Stewart, E. M., Gnann, C., McCarthy, F., Cabrera, J. P., Brunetti, R. M., Chhun, B. B., Dingle, G., Hein, M. Y., Huang, B. & 7 others, Mehta, S. B., Weissman, J. S., Gómez-Sjöberg, R., Itzhak, D. N., Royer, L. A., Mann, Matthias & Leonetti, M. D., 2022, In: Science. 375, 6585, eabi6983.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

      Diamanti, K., Cavalli, M., Pereira, M. J., Pan, G., Castillejo-López, C., Kumar, C., Mundt Madsen, Filip Oskar, Komorowski, J., Deshmukh, Atul Shahaji, Mann, Matthias, Korsgren, O., Eriksson, J. W. & Wadelius, C., 2022, In: Cell Reports Medicine. 3, 10, 21 p., 100763.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. PLCG1 is required for AML1-ETO leukemia stem cell self-renewal

      Schnoeder, T. M., Schwarzer, A., Jayavelu, A. K., Hsu, C-J., Kirkpatrick, J., Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S. A., Nafria, M., Jiang, L., Dai, Y-T., Chen, Z., Chen, S-J., Kellaway, S. G., Ptasinska, A., Ng, E. S. & 17 others, Stanley, E. G., Elefanty, A. G., Buschbeck, M., Bierhoff, H., Brodt, S., Matziolis, G., Fischer, K., Hochhaus, A., Chen, C., Heidenreich, O., Mann, Matthias, Lane, S. W., Bullinger, L., Ori, A., von Eyss, B., Bonifer, C. & Heidel, F. H., 2022, In: Blood. 139, 7, p. 1080-1097 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation

      Stafford, C. A., Gassauer, A. M., de Oliveira Mann, C. C., Tanzer, M. C., Fessler, E., Wefers, B., Nagl, D., Kuut, G., Sulek, K., Vasilopoulou, C., Schwojer, S. J., Wiest, A., Pfautsch, M. K., Wurst, W., Yabal, M., Fröhlich, T., Mann, Matthias, Gisch, N., Jae, L. T. & Hornung, V., 2022, In: Nature. 609, p. 590-596 28 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease

      Karayel, O., Virreira Winter, S., Padmanabhan, S., Kuras, Y. I., Vu, D. T., Tuncali, I., Merchant, K., Wills, A. M., Scherzer, C. R. & Mann, Matthias, 2022, In: Cell Reports Medicine. 3, 6, 20 p., 100661.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Rapid and In-Depth Coverage of the (Phospho-)Proteome With Deep Libraries and Optimal Window Design for dia-PASEF

      Skowronek, P., Thielert, Marvin Christoffer, Voytik, E., Tanzer, M. C., Hansen, F. M., Willems, S., Karayel, O., Brunner, A., Meier, F. & Mann, Matthias, 2022, In: Molecular and Cellular Proteomics. 21, 9, 15 p., 100279.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Spatial characterization of single tumor cells by proteomics

      Mund, Andreas & Mann, Matthias, 2022, In: Nature Biotechnology. 40, 8, p. 1186-1187 2 p.

      Research output: Contribution to journal › Comment/debate › Research

    25. Published

      Spatial proteomics in three-dimensional intact specimens

      Bhatia, H. S., Brunner, A-D., Öztürk, F., Kapoor, S., Rong, Z., Mai, H., Thielert, M., Ali, M., Al-Maskari, R., Paetzold, J. C., Kofler, F., Todorov, M. I., Molbay, M., Kolabas, Z. I., Negwer, M., Hoeher, L., Steinke, H., Dima, A., Gupta, B., Kaltenecker, D. & 11 others, Caliskan, Ö. S., Brandt, D., Krahmer, N., Müller, S., Lichtenthaler, S. F., Hellal, F., Bechmann, I., Menze, B., Theis, F., Mann, Matthias & Ertürk, A., 2022, In: Cell. 185, 26, p. 5040-5058.e19

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      The emerging role of mass spectrometry-based proteomics in drug discovery

      Meissner, F., Geddes-McAlister, J., Mann, Matthias & Bantscheff, M., 2022, In: Nature Reviews Drug Discovery. 21, p. 637-654 18 p.

      Research output: Contribution to journal › Review › Research › peer-review

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    ID: 5650809