Matthias Mann

Matthias Mann

Professor, head of research, Professor


  1. Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism

    von Scheidt, M., Zhao, Y., de Aguiar Vallim, T. Q., Che, N., Wierer, M., Seldin, M. M., Franzén, O., Kurt, Z., Pang, S., Bongiovanni, D., Yamamoto, M., Edwards, P. A., Ruusalepp, A., Kovacic, J. C., Mann, Matthias, Björkegren, J. L. M., Lusis, A. J., Yang, X. & Schunkert, H., 2021, In: Circulation. 143, 18, p. 1809-1823

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. AlphaTims: Indexing Trapped Ion Mobility Spectrometry-TOF Data for Fast and Easy Accession and Visualization

    Willems, S., Voytik, E., Skowronek, P., Strauss, Maximilian & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, p. 100149

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes

    Wigger, L., Barovic, M., Brunner, A-D., Marzetta, F., Schöniger, E., Mehl, F., Kipke, N., Friedland, D., Burdet, F., Kessler, C., Lesche, M., Thorens, B., Bonifacio, E., Legido-Quigley, C., Barbier Saint Hilaire, P., Delerive, P., Dahl, A., Klose, C., Gerl, M. J., Simons, K. & 7 others, Aust, D., Weitz, J., Distler, M., Schulte, A. M., Mann, Matthias, Ibberson, M. & Solimena, M., 28 Jun 2021, (E-pub ahead of print) In: Nature Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy

    Wierer, M., Werner, J., Wobst, J., Kastrati, A., Cepele, G., Aherrahrou, R., Sager, H. B., Erdmann, J., Dichgans, M., Flockerzi, V., Civelek, M., Dietrich, A., Mann, Matthias, Schunkert, H. & Kessler, T., 8 Apr 2021, (E-pub ahead of print) In: European Heart Journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Proteomic Analysis Identifies NDUFS1 and ATP5O as Novel Markers for Survival Outcome in Prostate Cancer

    Wiebringhaus, R., Pecoraro, M., Neubauer, H. A., Trachtová, K., Trimmel, B., Wieselberg, M., Pencik, J., Egger, G., Krall, C., Moriggl, R., Mann, Matthias, Hantusch, B. & Kenner, L., 30 Nov 2021, In: Cancers. 13, 23

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Molecular Origin of Blood-based Infrared Spectroscopic Fingerprints

    Voronina, L., Leonardo, C., Mueller-Reif, J. B., Geyer, P. E., Huber, M., Trubetskov, M., Kepesidis, K. V., Behr, J., Mann, Matthias, Krausz, F. & Žigman, M., 2021, In: Angewandte Chemie International Edition. 60, 31, p. 17060-17069

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Urinary proteome profiling for stratifying patients with familial Parkinson’s disease

    Virreira Winter, S., Karayel, O., Strauss, M. T., Padmanabhan, S., Surface, M., Merchant, K., Alcalay, R. N. & Mann, Matthias, 2021, In: EMBO Molecular Medicine. 13, 3, 19 p., e13257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Reply to "Quality control requirements for the correct annotation of lipidomics data"

    Vasilopoulou, C. G., Sulek, K., Brunner, A., Meitei, N. S., Schweiger-Hufnagel, U., Meyer, S. W., Barsch, A., Mann, Matthias & Meier, F., 2021, In: Nature Communications. 12, 4 p., 4772.

    Research output: Contribution to journalJournal articleResearch

  9. Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling

    Tanzer, M. C., Bludau, I., Stafford, C. A., Hornung, V. & Mann, Matthias, 18 Oct 2021, In: Nature Communications. 12, 1, p. 6053

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-β pathway

    Takahashi, M., Lio, C. J., Campeau, A., Steger, M., Ay, F., Mann, Matthias, Gonzalez, D. J., Jain, M. & Sharma, S., Apr 2021, In: Nature Immunology. 22, 4, p. 485-496 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila

    Tain, L. S., Sehlke, R., Meilenbrock, R. L., Leech, T., Paulitz, J., Chokkalingam, M., Nagaraj, N., Grönke, S., Fröhlich, J., Atanassov, I., Mann, Matthias, Beyer, A. & Partridge, L., 21 Apr 2021, In: eLife. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

    Stukalov, A., Girault, V., Grass, V., Karayel, O., Bergant, V., Urban, C., Haas, D. A., Huang, Y., Oubraham, L., Wang, A., Hamad, M. S., Piras, A., Hansen, F. M., Tanzer, M. C., Paron, I., Zinzula, L., Engleitner, T., Reinecke, M., Lavacca, T. M., Ehmann, R. & 10 others, Wölfel, R., Jores, J., Kuster, B., Protzer, U., Rad, R., Ziebuhr, J., Thiel, V., Scaturro, P., Mann, Matthias & Pichlmair, A., 12 Apr 2021, (E-pub ahead of print) In: Nature.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Homology-directed repair protects the replicating genome from metabolic assaults

    Somyajit, K., Spies, J., Coscia, F., Kirik, U., Rask, M., Lee, J., Neelsen, K. J., Mund, Andreas, Jensen, Lars Juhl, Paull, T. T., Mann, Matthias & Lukas, Jiri, 2021, In: Developmental Cell. 56, 4, p. 461-477.e7

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme

    Sherpa, D., Chrustowicz, J., Qiao, S., Langlois, C. R., Hehl, L. A., Gottemukkala, K. V., Hansen, F. M., Karayel, O., von Gronau, S., Prabu, J. R., Mann, Matthias, Alpi, A. F. & Schulman, B. A., 22 Apr 2021, (E-pub ahead of print) In: Molecular Cell.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions

    Procida, T., Friedrich, T., Jack, A. P. M., Peritore, M., Bönisch, C., Eberl, H. C., Daus, N., Kletenkov, K., Nist, A., Stiewe, T., Borggrefe, T., Mann, Matthias, Bartkuhn, M. & Hake, S. B., 12 Jan 2021, In: International Journal of Molecular Sciences. 22, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Cohort profile: the MUNICH Preterm and Term Clinical study (MUNICH-PreTCl), a neonatal birth cohort with focus on prenatal and postnatal determinants of infant and childhood morbidity

    Pangratz-Fuehrer, S., Genzel-Boroviczény, O., Bodensohn, W. E., Eisenburger, R., Scharpenack, J., Geyer, P. E., Müller-Reif, J. B., van Hagen, N., Müller, A. M., Jensen, Majken Karoline, Klein, C., Mann, Matthias & Nussbaum, C., 2021, In: BMJ Open. 11, 6, 13 p., e050652.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Defining NASH from a multi-omics systems biology perspective

    Niu, Lili, Sulek, K., Vasilopoulou, C. G., Santos, A., Albrechtsen, Nicolai Jacob Wewer, Rasmussen, Simon, Meier, F. & Mann, Matthias, 2021, In: Journal of Clinical Medicine. 10, 20, 22 p., 4673.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

    Nagao, H., Cai, W., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Batista, T. M., Pan, H., Dreyfuss, J. M., Mann, Matthias & Kahn, C. R., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 17, e2019474118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns

    Müller-Reif, J. B., Hansen, F. M., Schweizer, L., Treit, P. V., Geyer, P. E. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 10 p., 100082.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Protein profile of fiber types in human skeletal muscle: a single-fiber proteomics study

    Murgia, M., Nogara, L., Baraldo, M., Reggiani, C., Mann, Matthias & Schiaffino, S., 2021, In: Skeletal Muscle. 11, 1, 19 p., 24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation - Serial Fragmentation (PASEF) in Proteomics

    Meier, F., Park, M. A. & Mann, Matthias, 17 Aug 2021, (E-pub ahead of print) In: Molecular and Cellular Proteomics. p. 100138

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Deep learning the collisional cross sections of the peptide universe from a million experimental values

    Meier, F., Köhler, N. D., Brunner, A. D., Wanka, J. M. H., Voytik, E., Strauss, M. T., Theis, F. J. & Mann, Matthias, 2021, In: Nature Communications. 12, 12 p., 1185.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers

    Mayr, C. H., Simon, L. M., Leuschner, G., Ansari, M., Schniering, J., Geyer, P. E., Angelidis, I., Strunz, M., Singh, P., Kneidinger, N., Reichenberger, F., Silbernagel, E., Böhm, S., Adler, H., Lindner, M., Maurer, B., Hilgendorff, A., Prasse, A., Behr, J., Mann, M. & 3 others, Eickelberg, O., Theis, F. J. & Schiller, H. B., 2021, In: EMBO Molecular Medicine. e12871.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Ethical Principles, Constraints and Opportunities in Clinical Proteomics

    Porsdam Mann, Sebastian, Treit, P. V., Geyer, P. E., Omenn, G. S. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 14 p., 100046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Artificial intelligence for proteomics and biomarker discovery

    Mann, Matthias, Kumar, C., Zeng, W. & Strauss, M. T., 18 Aug 2021, In: Cell Systems. 12, 8, p. 759-770 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

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