Matthias Mann

Matthias Mann

Professor, head of research, Professor


  1. 2021
  2. Published

    Plasma proteomic data can contain personally identifiable, sensitive information and incidental findings

    Geyer, P. E., Porsdam Mann, Sebastian, Treit, P. V. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Protein profile of fiber types in human skeletal muscle: a single-fiber proteomics study

    Murgia, M., Nogara, L., Baraldo, M., Reggiani, C., Mann, Matthias & Schiaffino, S., 2021, In: Skeletal Muscle. 11, 1, 19 p., 24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Reply to "Quality control requirements for the correct annotation of lipidomics data"

    Vasilopoulou, C. G., Sulek, K., Brunner, A., Meitei, N. S., Schweiger-Hufnagel, U., Meyer, S. W., Barsch, A., Mann, Matthias & Meier, F., 2021, In: Nature Communications. 12, 4 p., 4772.

    Research output: Contribution to journalJournal articleResearch

  5. Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism

    von Scheidt, M., Zhao, Y., de Aguiar Vallim, T. Q., Che, N., Wierer, M., Seldin, M. M., Franzén, O., Kurt, Z., Pang, S., Bongiovanni, D., Yamamoto, M., Edwards, P. A., Ruusalepp, A., Kovacic, J. C., Mann, Matthias, Björkegren, J. L. M., Lusis, A. J., Yang, X. & Schunkert, H., 2021, In: Circulation. 143, 18, p. 1809-1823

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Urinary proteome profiling for stratifying patients with familial Parkinson’s disease

    Virreira Winter, S., Karayel, O., Strauss, M. T., Padmanabhan, S., Surface, M., Merchant, K., Alcalay, R. N. & Mann, Matthias, 2021, In: EMBO Molecular Medicine. 13, 3, 19 p., e13257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2020
  8. DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift

    Karayel, O., Michaelis, A. C., Mann, Matthias, Schulman, B. A. & Langlois, C. R., 22 Dec 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 51, p. 32806-32815 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Pharmacological and phosphoproteomic approaches to roles of protein kinase C in kappa opioid receptor-mediated effects in mice

    Liu, J. J., Chiu, Y., Chen, C., Huang, P., Mann, Matthias & Liu-Chen, L., 15 Dec 2020, In: Neuropharmacology. 181, p. 108324

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Dynamics in protein translation sustaining T cell preparedness

    Wolf, T., Jin, W., Zoppi, G., Vogel, I. A., Akhmedov, M., Bleck, C. K. E., Beltraminelli, T., Rieckmann, J. C., Ramirez, N. J., Benevento, M., Notarbartolo, S., Bumann, D., Meissner, F., Grimbacher, B., Mann, Matthias, Lanzavecchia, A., Sallusto, F., Kwee, I. & Geiger, R., 6 Jul 2020, (E-pub ahead of print) In: Nature Immunology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry

    Reim, A., Ackermann, R., Font-Mateu, J., Kammel, R., Beato, M., Nolte, S., Mann, Matthias, Russmann, C. & Wierer, M., 15 Jun 2020, In: Nature Communications. 11, 1, p. 3019

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Fam20C regulates protein secretion by Cab45 phosphorylation

    Hecht, T. K., Blank, B., Steger, M., Lopez, V., Beck, G., Ramazanov, B., Mann, Matthias, Tagliabracci, V. & von Blume, J., 1 Jun 2020, In: The Journal of Cell Biology. 219, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer

    Oberhuber, M., Pecoraro, M., Rusz, M., Oberhuber, G., Wieselberg, M., Haslinger, P., Gurnhofer, E., Schlederer, M., Limberger, T., Lagger, S., Pencik, J., Kodajova, P., Högler, S., Stockmaier, G., Grund-Gröschke, S., Aberger, F., Bolis, M., Theurillat, J-P., Wiebringhaus, R., Weiss, T. & 13 others, Haitel, A., Brehme, M., Wadsak, W., Griss, J., Mohr, T., Hofer, A., Jäger, A., Pollheimer, J., Egger, G., Koellensperger, G., Mann, Matthias, Hantusch, B. & Kenner, L., Apr 2020, In: Molecular Systems Biology. 16, 4, p. e9247

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation

    Trentini, D. B., Pecoraro, M., Tiwary, S., Cox, J., Mann, Matthias, Hipp, M. S. & Hartl, F. U., 25 Feb 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 8, p. 4099-4108 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Quantitative and Dynamic Catalogs of Proteins Released during Apoptotic and Necroptotic Cell Death

    Tanzer, M. C., Frauenstein, A., Stafford, C. A., Phulphagar, K., Mann, Matthias & Meissner, F., 28 Jan 2020, In: Cell Reports. 30, 4, p. 1260-1270.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

    Batista, T. M., Jayavelu, A. K., Albrechtsen, Nicolai Jacob Wewer, Iovino, S., Lebastchi, J., Pan, H., Dreyfuss, J. M., Krook, A., Zierath, Juleen R, Mann, Matthias & Kahn, C. R., 2020, In: Cell Metabolism. 32, 5, p. 844-859.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

    Cavalli, M., Diamanti, K., Pan, G., Spalinskas, R., Kumar, C., Deshmukh, Atul Shahaji, Mann, Matthias, Sahlén, P., Komorowski, J. & Wadelius, C., 2020, In: O M I C S: A Journal of Integrative Biology. 24, 4, 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A streamlined mass spectrometry-based proteomics workflow for large scale FFPE tissue analysis

    Coscia, F., Doll, S., Bech, J. M., Schweizer, L., Mund, Andreas, Lengyel, E., Lindebjerg, J., Madsen, G. I., Moreira, José & Mann, Matthias, 2020, In: Journal of Pathology. 251, p. 110-112

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Accurate MS-based Rab10 Phosphorylation Stoichiometry Determination as Readout for LRRK2 Activity in Parkinson’s Disease

    Karayel, O., Tonelli, F., Virreira Winter, S., Geyer, P. E., Fan, Y., Sammler, E. M., Alessi, D., Steger, M. & Mann, Matthias, 2020, In: Molecular and Cellular Proteomics. p. 1546-1560

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Atorvastatin for prevention of disease progression and hospitalisation in liver cirrhosis: protocol for a randomised, double-blind, placebo-controlled trial

    Kimer, N., Grønbæk, H., Fred, Rikard Göran, Hansen, Torben, Deshmukh, Atul Shahaji, Mann, Matthias & Bendtsen, Flemming, 2020, In: BMJ Open. 10, 1, 7 p., e035284.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome

    Fitzner, D., Bader, J. M., Penkert, H., Bergner, C. G., Su, M., Weil, M., Surma, M. A., Mann, Matthias, Klose, C. & Simons, M., 2020, In: Cell Reports. 32, 21 p., 108132.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease

    Hoffmann, Saskia, Pentakota, S., Mund, Andreas, Haahr, Peter Thorlund, Coscia, F., Gallo, M., Mann, Matthias, Taylor, Nicholas M I & Mailand, Niels, 2020, In: EMBO Reports. 21, 10, 14 p., e50662.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome

    Utami, K. H., Skotte, Niels Henning, Colaço, A. R., Yusof, N. A. B. M., Sim, B., Yeo, X. Y., Bae, H., Garcia-Miralles, M., Radulescu, C. I., Chen, Q., Chaldaiopoulou, G., Liany, H., Nama, S., Peteri, U. A., Sampath, P., Castrén, M. L., Jung, S., Mann, Matthias & Pouladi, M. A., 2020, In: Biological Psychiatry. 88, 6, p. 500-511

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis

    Karayel, O., Xu, P., Bludau, I., Bhoopalan, S. V., Yao, Y., Rita, F. C. A., Santos, A., Schulman, B. A., Alpi, A. F., Weiss, M. J. & Mann, Matthias, 2020, In: Molecular Systems Biology. 16, 12, 22 p., 9813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    LifeTime and improving European healthcare through cell-based interceptive medicine

    Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N., Kjems, J., Knoblich, J. A. & 31 others, Krabbe, G., Lichter, P., Linnarsson, S., Marine, J. C., Marioni, J. C., Marti-Renom, M. A., Netea, M. G., Nickel, D., Nollmann, M., Novak, H. R., Parkinson, H., Piccolo, S., Pinheiro, I., Pombo, A., Popp, C., Reik, W., Roman-Roman, S., Rosenstiel, P., Schultze, J. L., Stegle, O., Tanay, A., Testa, G., Thanos, D., Theis, F. J., Torres-Padilla, M. E., Valencia, A., Vallot, C., van Oudenaarden, A., Mann, Matthias, Nielsen, A. F. & LifeTime Community Working Groups, L. C. W. G., 2020, In: Nature. 587, 7834, p. 377-386 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

    Ngo, B., Kim, E., Osorio-Vasquez, V., Doll, S., Bustraan, S., Liang, R. J., Luengo, A., Davidson, S. M., Ali, A., Ferraro, G. B., Fischer, G. M., Eskandari, R., Kang, D. S., Ni, J., Plasger, A., Rajasekhar, V. K., Kastenhuber, E. R., Bacha, S., Sriram, R. K., Stein, B. D. & 20 others, Bakhoum, S. F., Snuderl, M., Cotzia, P., Healey, J. H., Mainolfi, N., Suri, V., Friedman, A., Manfredi, M., Sabatini, D. M., Jones, D. R., Yu, M., Zhao, J. J., Jain, R. K., Keshari, K. R., Davies, M. A., Vander Heiden, M. G., Hernando, E., Mann, Matthias, Cantley, L. C. & Pacold, M. E., 2020, In: Cancer Discovery. 10, 9, p. 1352-1373

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    MiT/TFEfactors controlER-phagy via transcriptional regulation ofFAM134B

    Cinque, L., De Leonibus, C., Iavazzo, M., Krahmer, N., Intartaglia, D., Salierno, F. G., De Cegli, R., Di Malta, C., Svelto, M., Lanzara, C., Maddaluno, M., Wanderlingh, L. G., Huebner, A. K., Cesana, M., Bonn, F., Polishchuk, E., Huebner, C. A., Conte, I., Dikic, I., Mann, M. & 4 others, Ballabio, A., Sacco, F., Grumati, P. & Settembre, C., 2020, In: EMBO Journal. 39, 17, 22 p., 105696.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 5650809