Jiri Lukas

Jiri Lukas

Executive Director, Professor

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    ORCID: 0000-0001-9087-506X

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    1. Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage

      Moudry, P., Lukas, Claudia, Macurek, L., Hanzlikova, H., Hodny, Z., Lukas, Jiri & Bartek, J., 15 Apr 2012, In: Cell Cycle. 11, 8, p. 1573-82 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

      Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Low-dose DNA damage and replication stress responses quantified by optimized automated single-cell image analysis

      Mistrik, M., Oplustilova, L., Lukas, Jiri & Bartek, J., 2009, In: Cell Cycle. 8, 16, p. 2592-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

      Melander, F., Bekker-Jensen, Simon Holst, Falck, J., Bartek, J., Mailand, Niels & Lukas, Jiri, 21 Apr 2008, In: Journal of Cell Biology. 181, 2, p. 213-26 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

      Marteijn, J. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Lans, H., Schwertman, P., Gourdin, A. M., Dantuma, N. P., Lukas, Jiri & Vermeulen, W., 2009, In: Journal of Cell Biology. 186, 6, p. 835-47 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress

      Mailand, Niels, Bekker-Jensen, Simon Holst, Bartek, J. & Lukas, Jiri, 2006, In: Molecular Cell. 23, 3, p. 307-18 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

      Mailand, Niels, Lukas, Claudia, Kaiser, B. K., Jackson, P. K., Bartek, J. & Lukas, Jiri, Apr 2002, In: Nature Cell Biology. 4, 4, p. 317-22 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

      Mailand, Niels, Bekker-Jensen, Simon Holst, Faustrup, H., Melander, F., Bartek, J., Lukas, Claudia & Lukas, Jiri, 2007, In: Cell. 131, 5, p. 887-900 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability.

      Mailand, Niels, Podtelejnikov, A. V., Groth, Anja, Mann, M., Bartek, J. & Lukas, Jiri, 2002, In: EMBO Journal. 21, 21, p. 5911-20 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Rapid destruction of human Cdc25A in response to DNA damage

      Mailand, Niels, Falck, J., Lukas, Claudia, Syljuåsen, R. G., Welcker, M., Bartek, J. & Lukas, Jiri, 26 May 2000, In: Science (New York, N.Y.). 288, 5470, p. 1425-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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