Guillermo Montoya

Guillermo Montoya

Professor, head of research, Professor

Member of:

    ORCID: 0000-0002-8269-3941

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    1. Published

      Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold

      Molina, R., Marcaida, M. J., Redondo, P., Marenchino, M., Duchateau, P., D'Abramo, M., Montoya, Guillermo & Prieto, J., 2015, In: The Journal of Biological Chemistry. 290, 30, p. 18534-18544 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency

      Sukparangsi, W., Morganti, E., Lowndes, Molly, Mayeur, H., Weisser, Melanie, Hammachi, F., Peradziryi, H., Roske, F., Hölzenspies, J., Livigni, A., Godard, B. G., Sugahara, F., Kuratani, S., Montoya, Guillermo, Frankenberg, S. R., Mazan, S. & Brickman, Joshua Mark, 2022, In: Nature Communications. 13, 1, 21 p., 5537.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Expression, purification, crystallization and preliminary X-ray diffraction analysis of the novel modular DNA-binding protein BurrH in its apo form and in complex with its target DNA

      Stella, S., Molina, R., Bertonatti, C., Juillerrat, A. & Montoya, Guillermo, 1 Jan 2014, In: Acta Crystallographica Section F:Structural Biology Communications. 70, 1, p. 87-91 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Functional and in silico assessment of MAX variants of unknown significance

      Comino-Méndez, I., Leandro-García, L. J., Montoya, G., Inglada-Pérez, L., de Cubas, A. A., Currás-Freixes, M., Tysoe, C., Izatt, L., Letón, R., Gómez-Graña, Á., Mancikova, V., Apellániz-Ruiz, M., Mannelli, M., Schiavi, F., Favier, J., Gimenez-Roqueplo, A-P., Timmers, H. J. L. M., Roncador, G., Garcia, J. F., Rodríguez-Antona, C. & 2 others, Robledo, M. & Cascón, A., Nov 2015, In: Journal of Molecular Medicine. 93, 11, p. 1247-55 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage

      Slaymaker, I. M., Mesa, Pablo, Kellner, M. J., Kannan, S., Brignole, E., Koob, J., Feliciano, P. R., Stella, S., Abudayyeh, O. O., Gootenberg, J. S., Strecker, J., Montoya, Guillermo & Zhang, F., 2019, In: Cell Reports. 26, 13, p. 3741-3751.e5 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      How do CRISPR-Cas RNA-guided endonucleases cut specific DNA regions for Genome Editing?

      Montoya, Guillermo, 2018, In: Acta Crystallographica Section A: Foundations and Advances. 74, p. E3 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    7. Published

      Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening

      Lee, S., Tran, K. T., Vazquez-Uribe, R., Gotfredsen, C. H., Clausen, M. H., Mendez, B. L., Montoya, Guillermo, Bach, Anders & Sommer, M. O. A., 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 3266–3305

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics

      Molina, R., Besker, N., Marcaida, M. J., Montoya, Guillermo, Prieto, J. & D'Abramo, M., 8 Mar 2016, In: ACS chemical biology. 11, 5, p. 1401–1407

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Mechanics of CRISPR-Cas12a and engineered variants on λ-DNA

      Paul, B., Chaubet, L., Verver, D. E. & Montoya, Guillermo, 2022, In: Nucleic Acids Symposium Series. 50, 9, p. 5208-5225 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Molecular Basis of the Mechanisms Controlling MASTL

      Hermida, D., Mortuza, G. B., Pedersen, Anna-Kathrine, Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Molecular architecture of the Jumonji C family histone demethylase KDM5B

      Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Molecular architecture of the recombinant human MCM2-7 helicase in complex with nucleotides and DNA

      Boskovic, J., Bragado-Nilsson, E., Saligram Prabhakar, B., Yefimenko, I., Martínez-Gago, J., Muñoz, S., Méndez, J. & Montoya, Guillermo, 16 Sep 2016, In: Cell Cycle. 15, 18, p. 2431-40 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Molecular basis of Tousled-Like Kinase 2 activation

      Mortuza, G. B., Hermida, D., Pedersen, Anna-Kathrine, Segura-Bayona, S., López-Méndez, B., Redondo, P., Rüther, P., Pozdnyakova, I., Garrote, A. M., Muñoz, I. G., Villamor-Payà, M., Jauset, C., Olsen, Jesper Velgaard, Stracker, T. H. & Montoya, Guillermo, 2018, In: Nature Communications. 9, 1, p. 2535 2535.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Molecular basis of cyclic tetra-oligoadenylate processing by small standalone CRISPR-Cas ring nucleases

      Molina, R., García Martín, Ricardo, López-Méndez, B., Jensen, A. L. G., Ciges Tomas, Jose Rafael, Marchena-Hurtado, J., Stella, S. & Montoya, Guillermo, 2022, In: Nucleic Acids Research. 50, 19, p. 11199-11213 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

      Redondo, P., Prieto, J., Muñoz, I. G., Alibés, A., Stricher, F., Serrano, L., Cabaniols, J., Daboussi, F., Arnould, S., Perez, C., Duchateau, P., Pâques, F., Blanco, F. J. & Montoya, Guillermo, 6 Nov 2008, In: Nature. 456, 7218, p. 107-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Molecular scissors for in situ cellular repair

      Prieto, J., Molina, R. & Montoya, Guillermo, 31 Jan 2012, In: Critical Reviews in Biochemistry and Molecular Biology. 47, 3, p. 207-21 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    17. Published

      Non-specific protein-DNA interactions control I-CreI target binding and cleavage

      Molina, R., Redondo, P., Stella, S., Marenchino, M., D'Abramo, M., Gervasio, F. L., Charles Epinat, J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 1 Aug 2012, In: Nucleic Acids Research. 40, 14, p. 6936-6945 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

      Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Realizing integration in structural biology: The 2022 ISBUC Annual Meeting

      Kragelund, Birthe Brandt, Loland, Claus Juul, Montoya, Guillermo, Hatzakis, Nikos, Martinez, Karen Laurence, Gajhede, Michael, Christensen, Caspar Elo & Holt, Lucy, 2023, In: Structure. 31, 7, p. 747-754

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Structural basis of CRISPR-Cas Type III prokaryotic defence systems

      Molina, R., Sofos, N. & Montoya, Guillermo, 2020, In: Current Opinion in Structural Biology. 65, p. 119-129 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    21. Published

      Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases

      Molina Monterrubio, R. A., Jensen, A. L. G., Marchena-Hurtado, J., López-Méndez, B., Stella, S. & Montoya, Guillermo, 2021, In: Nucleic Acids Research. 49, 21, p. 12577-12590 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI

      Alba, J., Marcaida, M. J., Prieto, J., Montoya, Guillermo, Molina, R. & D'Abramo, M., Dec 2017, In: Journal of Computer - Aided Molecular Design. 31, 12, p. 1063-1072 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

      Molina, R., Stella, S., Feng, M., Sofos, N., Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, Guillermo, 2019, In: Nature Communications. 10, 14 p., 4302.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Structure of p15PAF-PCNA complex and implications for clamp sliding during DNA replication and repair

      De Biasio, A., de Opakua, A. I., Mortuza, G. B., Molina, R., Cordeiro, T. N., Castillo, F., Villate, M., Merino, N., Delgado, S., Gil-Cartón, D., Luque, I., Diercks, T., Bernadó, P., Montoya, Guillermo & Blanco, F. J., 12 Mar 2015, In: Nature Communications. 6, p. 1-12 6439.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism

      Stella, S., Molina, R., Yefimenko, I., Prieto, J., Silva, G., Bertonati, C., Juillerat, A., Duchateau, P. & Montoya, Guillermo, 2013, In: Acta Crystallographica Section D: Biological Crystallography. 69, 9, p. 1707-1716 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 93716435