Guillermo Montoya

Guillermo Montoya

Professor, head of research, Professor

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    ORCID: 0000-0002-8269-3941

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    1. Published

      Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics

      Molina, R., Besker, N., Marcaida, M. J., Montoya, Guillermo, Prieto, J. & D'Abramo, M., 8 Mar 2016, In: ACS chemical biology. 11, 5, p. 1401–1407

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold

      Molina, R., Marcaida, M. J., Redondo, P., Marenchino, M., Duchateau, P., D'Abramo, M., Montoya, Guillermo & Prieto, J., 2015, In: The Journal of Biological Chemistry. 290, 30, p. 18534-18544 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification

      Molina, R., Redondo, P., López-Méndez, B., Villate, M., Merino, N., Blanco, F. J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 27 Nov 2015, In: The Journal of Biological Chemistry. 290, 48, p. 28727-36 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Structural basis of CRISPR-Cas Type III prokaryotic defence systems

      Molina, R., Sofos, N. & Montoya, Guillermo, 2020, In: Current Opinion in Structural Biology. 65, p. 119-129 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    5. Published

      Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases

      Molina Monterrubio, R. A., Jensen, A. L. G., Marchena-Hurtado, J., López-Méndez, B., Stella, S. & Montoya, Guillermo, 2021, In: Nucleic Acids Research. 49, 21, p. 12577-12590 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Editorial overview: Protein-nucleic acid interactions: 'Takes two to Tango'

      Montoya, Guillermo & Carlomagno, T., 2020, In: Current Opinion in Structural Biology. 65, p. v-vi 2 p.

      Research output: Contribution to journal › Editorial › Research

    7. Published

      How do CRISPR-Cas RNA-guided endonucleases cut specific DNA regions for Genome Editing?

      Montoya, Guillermo, 2018, In: Acta Crystallographica Section A: Foundations and Advances. 74, p. E3 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    8. Published

      XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation

      Mortuza, G. B., Cavazza, T., Garcia-Mayoral, M. F., Hermida, D., Peset, I., Pedrero, J. G., Merino, N., Blanco, F. J., Lyngsø, J., Bruix, M., Pedersen, J. S., Vernos, I. & Montoya, Guillermo, 29 Sep 2014, In: Nature Communications. 5, p. 1-12 12 p., 5072.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Molecular basis of Tousled-Like Kinase 2 activation

      Mortuza, G. B., Hermida, D., Pedersen, Anna-Kathrine, Segura-Bayona, S., López-Méndez, B., Redondo, P., Rüther, P., Pozdnyakova, I., Garrote, A. M., Muñoz, I. G., Villamor-Payà, M., Jauset, C., Olsen, Jesper Velgaard, Stracker, T. H. & Montoya, Guillermo, 2018, In: Nature Communications. 9, 1, p. 2535 2535.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin

      Muñoz, I. G., Yébenes, H., Zhou, M., Mesa, Pablo, Serna, M., Park, A. Y., Bragado-Nilsson, E., Beloso, A., de Cárcer, G., Malumbres, M., Robinson, C. V., Valpuesta, J. M. & Montoya, Guillermo, Jan 2011, In: Nature Structural & Molecular Biology. 18, 1, p. 14-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Mechanics of CRISPR-Cas12a and engineered variants on λ-DNA

      Paul, B., Chaubet, L., Verver, D. E. & Montoya, Guillermo, 2022, In: Nucleic Acids Symposium Series. 50, 9, p. 5208-5225 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      CRISPR-Cas12a: functional overview and applications

      Paul, B. & Montoya, Guillermo, 2020, In: Biomedical Journal. 43, 1, p. 8-17

      Research output: Contribution to journal › Review › Research › peer-review

    13. Published

      A novel TPR-BEN domain interaction mediates PICH-BEND3 association

      Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex

      Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions

      Prieto, J., Redondo, P., Merino, N., Villate, M., Montoya, Guillermo, Blanco, F. J. & Molina, R., Jun 2016, In: Acta crystallographica. Section F, Structural biology communications. 72, Pt 6, p. 473-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Understanding the indirect DNA read-out specificity of I-CreI Meganuclease

      Prieto, J., Redondo, P., López-Méndez, B., D'Abramo, M., Merino, N., Blanco, F. J., Duchateau, P., Montoya, Guillermo & Molina, R., 2018, In: Scientific Reports. 8, p. 1-9 10286.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Molecular scissors for in situ cellular repair

      Prieto, J., Molina, R. & Montoya, Guillermo, 31 Jan 2012, In: Critical Reviews in Biochemistry and Molecular Biology. 47, 3, p. 207-21 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    18. Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA

      Redondo, P., Merino, N., Villate, M., Blanco, F. J., Montoya, Guillermo & Molina, R., Feb 2014, In: Acta crystallographica. Section F, Structural biology communications. 70, Pt 2, p. 256-9 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

      Redondo, P., Prieto, J., Muñoz, I. G., Alibés, A., Stricher, F., Serrano, L., Cabaniols, J., Daboussi, F., Arnould, S., Perez, C., Duchateau, P., Pâques, F., Blanco, F. J. & Montoya, Guillermo, 6 Nov 2008, In: Nature. 456, 7218, p. 107-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      TnpB structure reveals minimal functional core of Cas12 nuclease family

      Sasnauskas, G., Tamulaitiene, G., Druteika, G., Carabias del Rey, Arturo, Silanskas, A., Kazlauskas, D., Venclovas, Č., Montoya, Guillermo, Karvelis, T. & Siksnys, V., 2023, In: Nature. 616, 7956, p. 384-389 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage

      Slaymaker, I. M., Mesa, Pablo, Kellner, M. J., Kannan, S., Brignole, E., Koob, J., Feliciano, P. R., Stella, S., Abudayyeh, O. O., Gootenberg, J. S., Strecker, J., Montoya, Guillermo & Zhang, F., 2019, In: Cell Reports. 26, 13, p. 3741-3751.e5 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas

      Sofos, N., Feng, M., Stella, S., Pape, T., Fuglsang, Anders, Lin, Jinzhong, Huang, Q., Li, Y., She, Q. & Montoya, Guillermo, 2020, In: Molecular Cell. 79, 5, p. 741-757

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex

      Starnes, L. M., Su, D., Pikkupeura, L. M., Weinert, B. T., Santos, M. A., Mund, A., Soria, R., Cho, Y-W., Pozdnyakova, I., Kubec Højfeldt, M., Lages Lino Vala, A., Yang, W., López-Méndez, B., Lee, J-E., Peng, W., Yuan, J., Ge, K., Montoya, G., Nussenzweig, A., Choudhary, C. R. & 1 others, Daniel, J. A., 15 Jan 2016, In: Genes & Development. 30, 2, p. 149-163 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity

      Stella, S., Mesa, Pablo, Thomsen, J., Paul, B., Alcon, P., Jensen, S. B., Moses, M. E., Montoya, Guillermo & Hatzakis, Nikos, 7 Feb 2020, In: Biophysical Journal. 118, 3, p. 223A-224A 2 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    25. Published

      Class 2 CRISPR-Cas RNA-guided endonucleases: Swiss Army knives of genome editing

      Stella, S., Alcón, P. & Montoya, Guillermo, Nov 2017, In: Nature Structural and Molecular Biology. 24, 11, p. 882-892 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

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    ID: 93716435