Alicia Lundby
Affiliated Associate Professor, Professor with special responsibilities, Professor MSO
Mann Group
Blegdamsvej 3B
2200 København N
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3, 2200 København N.
Member of:
- 2024
- E-pub ahead of print
GLP-1 increases heart rate by a direct action on the sinus node
Lubberding, A. F., Veedfald, S., Achter, J. S., Nissen, S. D., Soattin, L., Sorrentino, A., Vega, E. T., Linz, B., Eggertsen, C. H. E., Mulvey, J., Toräng, S., Larsen, S. A., Nissen, A., Petersen, L. G., Bilir, S. E., Bentzen, B. H., Rosenkilde, M. M., Hartmann, B., Lilleør, T. N. B., Qazi, S. & 6 others, , 4 Jun 2024, (E-pub ahead of print) In: Cardiovascular Research.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Proteomics couples electrical remodelling to inflammation in a murine model of heart failure with sinus node dysfunction
Kahnert, K., Soattin, L., Mills, R. W., Wilson, C., Maurya, S., Sorrentino, A., Al-Othman, S., Tikhomirov, R., van de Vegte, Y. J., Hansen, F. B., Achter, J., Hu, W., Zi, M., Smith, M., van der Harst, P., Olesen, M. S., Olsen, K. B., Banner, J., Jensen, T. H. L., Zhang, H. & 3 others, , 2024, (E-pub ahead of print) In: Cardiovascular Research. cvae054.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Functional modulation of a pH-sensitive ion channel by a transporter family
Poulsen, Mette Homann, Xue, F., Maurya, S. R., Kickinger, Stefanie, Usher, Samuel George, Wellendorph, Petrine, Lundby, Alicia & Pless, Stephan, 2023, In: Biophysical Journal. 122, 3 Suppl. 1, p. 249aResearch output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram
Maurya, S., Mills, Robert William, Kahnert, Konstantin, Chiang, D. Y., Bertoli, G., Lundegaard, Pia Rengtved, Duran, M. P. H., Zhang, M., Rothenberg, E., George, A. L., MacRae, C. A., Delmar, M. & Lundby, Alicia, 2023, In: Nature Cardiovascular Research. 2, 7, p. 673-692 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts
Sorrentino, Andrea, Bagwan, N., Linscheid, N., Poulsen, P. C., Kahnert, Konstantin, Thomsen, Morten Bækgaard, Delmar, M. & Lundby, Alicia, Dec 2022, In: Scientific Reports. 12, 1, 13 p., 4760.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo
Herum, K. M., Weng, Guangzheng, Kahnert, Konstantin, Waikel, R., Milburn, G., Conger, A., Anaya, P., Campbell, K. S., Lundby, Alicia, Won, K. J. & Brakebusch, Cord Herbert, 2022, In: Matrix Biology Plus. 15, 100113.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts
Van Opbergen, C. J. M., Bagwan, N., Maurya, S. R., Kim, J. C., Smith, A. N., Blackwell, D. J., Johnston, J. N., Knollmann, B. C., Cerrone, M., Lundby, Alicia & Delmar, M., 2022, In: Circulation. 145, 19, p. 1480-1496Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse
Roselli, C., Yu, M., Nauffal, V., Georges, A., Yang, Q., Love, K., Weng, L-C., Delling, F. N., Maurya, S. R., Schrölkamp, M., Tfelt-Hansen, J., Hagège, A., Jeunemaitre, X., Debette, S., Amouyel, P., Guan, W., Muehlschlegel, J. D., Body, S. C., Shah, S., Samad, Z. & 34 others, , 2022, In: European Heart Journal. 43, 17, p. 1668–1680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC
Perez-Hernandez, M., van Opbergen, C. J. M., Bagwan, N., Vissing, C. R., Marron-Linares, G. M., Zhang, M., Vega, E. T., Sorrentino, A., Drici, L., Sulek, K., Zhai, R., Hansen, F. B., Christensen, A. H., Boesgaard, S., Gustafsson, F., Rossing, K., Small, E. M., Davies, M. J., Rothenberg, E., Sato, P. Y. & 6 others, , 2022, In: Circulation. 146, 11, p. 851-867Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2 Feb 2021, bioRxiv, p. 1-34, 34 p.Research output: Working paper › Preprint › Research
- Published
Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts
Sorrentino, Andrea, Bagwan, N., Linscheid, N., Poulsen, P., Kahnert, Konstantin, Thomsen, Morten Bækgaard, Delmar, M. & Lundby, Alicia, 2021, In: European Heart Journal. 42, Suppl. 1, p. 3294-3294 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Oncotherapeutic Protein Kinase Inhibitors Associated With Pro-Arrhythmic Liability
Ye, J. Z., Hansen, F. B., Mills, Robert William & Lundby, Alicia, 2021, In: JACC: CardioOncology. 3, 1, p. 88-97Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide profiling and mapping of post translational modifications in human hearts
Bagwan, N., El Ali, Henrik H. & Lundby, Alicia, 2021, In: Scientific Reports. 11, 1, 10 p., 2184.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteome comparison of human hearts with those of model organisms
Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Ibrutinib-Mediated Atrial Fibrillation Attributable to Inhibition of C-Terminal Src Kinase
Xiao, L., Salem, J., Clauss, S., Hanley, A., Bapat, A., Hulsmans, M., Iwamoto, Y., Wojtkiewicz, G., Cetinbas, M., Schloss, M. J., Tedeschi, J., Lebrun-Vignes, B., Lundby, Alicia, Sadreyev, R., Moslehi, J., Nahrendorf, M., Ellinor, P. T. & Milan, D. J., 2020, In: Circulation. 142, 25, p. 2443-2455 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues
Emdal, Kristina Bennet & Lundby, Alicia, 2020, In: Molecular & Cellular Oncology. 7, 1, 3 p., e1692643.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts
Poulsen, P. C., Schrölkamp, Maren, Bagwan, N., Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics of human heart samples collected In vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation
Linscheid, N., Poulsen, P. C., Pedersen, I. D., Gregers, E., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Olsen, Jesper Velgaard, Delmar, M. & Lundby, Alicia, 2020, In: Molecular and Cellular Proteomics. 19, 7, p. 1132-1144Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Disruption of Ca2+i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice
Kim, J., Perez-Hernandez, M., Alvarado, F. J., Maurya, S. R., Montnach, J., Yin, Y., Zhang, M., Lin, X., Vasquez, C., Heguy, A., Liang, F., Woo, S., Morley, G. E., Rothenberg, E., Lundby, Alicia, Valdivia, H. H., Cerrone, M. & Delmar, M., 2019, In: Circulation. 140, 12, p. 1015-1030Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reevaluation of genetic variants previously associated with arrhythmogenic right ventricular cardiomyopathy integrating population-based cohorts and proteomics data
Ye, J. Z., Delmar, M., Lundby, Alicia & Olesen, Morten Steen Salling, 2019, In: Clinical Genetics. 96, 6, p. 506-514Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Control of endothelial cell tube formation by Notch ligand intracellular domain interactions with activator protein 1 (AP-1)
Forghany, Z., Robertson, F., Lundby, Alicia, Olsen, Jesper Velgaard & Baker, D. A., 2018, In: Journal of Biological Chemistry. 293, 4, p. 1229-1242 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10426
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52 Genetic Loci Influencing Myocardial Mass
Research output: Contribution to journal › Journal article › Research › peer-review
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Research output: Contribution to journal › Journal article › Research › peer-review
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378
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Research output: Contribution to journal › Journal article › Research › peer-review
Published