Guillermo Montoya
Professor, head of research, Professor
- 2008
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases
Redondo, P., Prieto, J., Muñoz, I. G., Alibés, A., Stricher, F., Serrano, L., Cabaniols, J., Daboussi, F., Arnould, S., Perez, C., Duchateau, P., Pâques, F., Blanco, F. J. & Montoya, Guillermo, 6 Nov 2008, In: Nature. 456, 7218, p. 107-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin
Muñoz, I. G., Yébenes, H., Zhou, M., Mesa, Pablo, Serna, M., Park, A. Y., Bragado-Nilsson, E., Beloso, A., de Cárcer, G., Malumbres, M., Robinson, C. V., Valpuesta, J. M. & Montoya, Guillermo, Jan 2011, In: Nature Structural & Molecular Biology. 18, 1, p. 14-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Molecular scissors for in situ cellular repair
Prieto, J., Molina, R. & Montoya, Guillermo, 31 Jan 2012, In: Critical Reviews in Biochemistry and Molecular Biology. 47, 3, p. 207-21 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Non-specific protein-DNA interactions control I-CreI target binding and cleavage
Molina, R., Redondo, P., Stella, S., Marenchino, M., D'Abramo, M., Gervasio, F. L., Charles Epinat, J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 1 Aug 2012, In: Nucleic Acids Research. 40, 14, p. 6936-6945 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
5'-Cytosine-phosphoguanine (CpG) methylation impacts the activity of natural and engineered meganucleases
Valton, J., Daboussi, F., Leduc, S., Molina, R., Redondo, P., Macmaster, R., Montoya, Guillermo & Duchateau, P., 31 Aug 2012, In: The Journal of Biological Chemistry. 287, 36, p. 30139-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism
Stella, S., Molina, R., Yefimenko, I., Prieto, J., Silva, G., Bertonati, C., Juillerat, A., Duchateau, P. & Montoya, Guillermo, 2013, In: Acta Crystallographica Section D: Biological Crystallography. 69, 9, p. 1707-1716 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Directly from the source: endogenous preparations of molecular machines
Mesa, Pablo, Deniaud, A., Montoya, Guillermo & Schaffitzel, C., Jun 2013, In: Current Opinion in Structural Biology. 23, 3, p. 319-25 7 p.Research output: Contribution to journal › Review › Research › peer-review
- 2014
- Published
BuD, a helix-loop-helix DNA-binding domain for genome modification
Stella, S., Molina, R., López-Méndez, B., Juillerat, A., Bertonati, C., Daboussi, F., Campos-Olivas, R., Duchateau, P. & Montoya, Guillermo, 2014, In: Acta Crystallographica Section D: Structural Biology. 70, 7, p. 2042-2052 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Expression, purification, crystallization and preliminary X-ray diffraction analysis of the novel modular DNA-binding protein BurrH in its apo form and in complex with its target DNA
Stella, S., Molina, R., Bertonatti, C., Juillerrat, A. & Montoya, Guillermo, 1 Jan 2014, In: Acta Crystallographica Section F:Structural Biology Communications. 70, 1, p. 87-91 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA
Redondo, P., Merino, N., Villate, M., Blanco, F. J., Montoya, Guillermo & Molina, R., Feb 2014, In: Acta crystallographica. Section F, Structural biology communications. 70, Pt 2, p. 256-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive analysis of the specificity of transcription activator-like effector nucleases
Juillerat, A., Dubois, G., Valton, J., Thomas, S., Stella, S., Maréchal, A., Langevin, S., Benomari, N., Bertonati, C., Silva, G. H., Daboussi, F., Epinat, J., Montoya, Guillermo, Duclert, A. & Duchateau, P., Apr 2014, In: Nucleic Acids Research. 42, 8, p. 5390-402 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation
Mortuza, G. B., Cavazza, T., Garcia-Mayoral, M. F., Hermida, D., Peset, I., Pedrero, J. G., Merino, N., Blanco, F. J., Lyngsø, J., Bruix, M., Pedersen, J. S., Vernos, I. & Montoya, Guillermo, 29 Sep 2014, In: Nature Communications. 5, p. 1-12 12 p., 5072.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold
Molina, R., Marcaida, M. J., Redondo, P., Marenchino, M., Duchateau, P., D'Abramo, M., Montoya, Guillermo & Prieto, J., 2015, In: The Journal of Biological Chemistry. 290, 30, p. 18534-18544 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualizing phosphodiester-bond hydrolysis by an endonuclease
Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M. J., Orozco, M., Prieto, J. & Montoya, Guillermo, Jan 2015, In: Nature Structural and Molecular Biology. 22, 1, p. 65-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of p15PAF-PCNA complex and implications for clamp sliding during DNA replication and repair
De Biasio, A., de Opakua, A. I., Mortuza, G. B., Molina, R., Cordeiro, T. N., Castillo, F., Villate, M., Merino, N., Delgado, S., Gil-Cartón, D., Luque, I., Diercks, T., Bernadó, P., Montoya, Guillermo & Blanco, F. J., 12 Mar 2015, In: Nature Communications. 6, p. 1-12 6439.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional and in silico assessment of MAX variants of unknown significance
Comino-Méndez, I., Leandro-García, L. J., Montoya, G., Inglada-Pérez, L., de Cubas, A. A., Currás-Freixes, M., Tysoe, C., Izatt, L., Letón, R., Gómez-Graña, Á., Mancikova, V., Apellániz-Ruiz, M., Mannelli, M., Schiavi, F., Favier, J., Gimenez-Roqueplo, A-P., Timmers, H. J. L. M., Roncador, G., Garcia, J. F., Rodríguez-Antona, C. & 2 others, , Nov 2015, In: Journal of Molecular Medicine. 93, 11, p. 1247-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification
Molina, R., Redondo, P., López-Méndez, B., Villate, M., Merino, N., Blanco, F. J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 27 Nov 2015, In: The Journal of Biological Chemistry. 290, 48, p. 28727-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase
Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex
Starnes, L. M., Su, D., Pikkupeura, L. M., Weinert, B. T., Santos, M. A., Mund, A., Soria, R., Cho, Y-W., Pozdnyakova, I., Kubec Højfeldt, M., Lages Lino Vala, A., Yang, W., López-Méndez, B., Lee, J-E., Peng, W., Yuan, J., Ge, K., Montoya, G., Nussenzweig, A., Choudhary, C. R. & 1 others, , 15 Jan 2016, In: Genes & Development. 30, 2, p. 149-163 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics
Molina, R., Besker, N., Marcaida, M. J., Montoya, Guillermo, Prieto, J. & D'Abramo, M., 8 Mar 2016, In: ACS chemical biology. 11, 5, p. 1401–1407Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions
Prieto, J., Redondo, P., Merino, N., Villate, M., Montoya, Guillermo, Blanco, F. J. & Molina, R., Jun 2016, In: Acta crystallographica. Section F, Structural biology communications. 72, Pt 6, p. 473-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genome editing revolution: A CRISPR-Cas TALE off-target story
Stella, S. & Montoya, Guillermo, Jul 2016, In: BioEssays. 38, S1, p. S4-S13Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex
Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular architecture of the recombinant human MCM2-7 helicase in complex with nucleotides and DNA
Boskovic, J., Bragado-Nilsson, E., Saligram Prabhakar, B., Yefimenko, I., Martínez-Gago, J., Muñoz, S., Méndez, J. & Montoya, Guillermo, 16 Sep 2016, In: Cell Cycle. 15, 18, p. 2431-40 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 93716435
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Molecular basis of Tousled-Like Kinase 2 activation
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TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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