Matthias Mann
Professor, head of research, Professor
YBX1 mediates translation of oncogenic transcripts to control cell competition in AML
Perner, F., Schnoeder, T. M., Xiong, Y., Jayavelu, A. K., Mashamba, N., Santamaria, N. T., Huber, N., Todorova, K., Hatton, C., Perner, B., Eifert, T., Murphy, C., Hartmann, M., Hoell, J. I., Schröder, N., Brandt, S., Hochhaus, A., Mertens, P. R., Mann, M., Armstrong, S. A. & 2 others, , Feb 2022, In: Leukemia. 36, 2, p. 426-437 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unbiased spatial proteomics with single-cell resolution in tissues
Mund, Andreas, Brunner, A. & Mann, Matthias, 2022, In: Molecular Cell. 82, 12, p. 2335-2349 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation
Brunner, A., Thielert, Marvin Christoffer, Vasilopoulou, C., Ammar, C., Coscia, F., Mund, Andreas, Hoerning, O. B., Bache, N., Apalategui, A., Lubeck, M., Richter, S., Fischer, D. S., Raether, O., Park, M. A., Meier, F., Theis, F. J. & Mann, Matthias, 2022, In: Molecular Systems Biology. 18, 3, 15 p., e10798.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards Precision Dermatology: Emerging Role of Proteomic Analysis of the Skin
Fredman, G., Skov, Lone, Mann, Matthias & Dyring-Andersen, Beatrice, 2022, In: Dermatology. 238, p. 185–194Research output: Contribution to journal › Review › Research › peer-review
- Published
The structural context of posttranslational modifications at a proteome-wide scale
Bludau, I., Willems, S., Zeng, W. F., Strauss, Maximilian, Hansen, F. M., Tanzer, M. C., Karayel, O., Schulman, B. A. & Mann, Matthias, 2022, In: PLOS Biology. 20, 5, 23 p., e3001636.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The emerging role of mass spectrometry-based proteomics in drug discovery
Meissner, F., Geddes-McAlister, J., Mann, Matthias & Bantscheff, M., 2022, In: Nature Reviews Drug Discovery. 21, p. 637-654 18 p.Research output: Contribution to journal › Review › Research › peer-review
Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
Mehta, S., Buyanbat, A., Kai, Y., Karayel, O., Goldman, S. R., Seruggia, D., Zhang, K., Fujiwara, Y., Donovan, K. A., Zhu, Q., Yang, H., Nabet, B., Gray, N. S., Mann, Matthias, Fischer, E. S., Adelman, K. & Orkin, S. H., 18 Aug 2022, In: Cell Chemical Biology. 29, 8, p. 1273-1287.e8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial proteomics in three-dimensional intact specimens
Bhatia, H. S., Brunner, A-D., Öztürk, F., Kapoor, S., Rong, Z., Mai, H., Thielert, M., Ali, M., Al-Maskari, R., Paetzold, J. C., Kofler, F., Todorov, M. I., Molbay, M., Kolabas, Z. I., Negwer, M., Hoeher, L., Steinke, H., Dima, A., Gupta, B., Kaltenecker, D. & 11 others, , 2022, In: Cell. 185, 26, p. 5040-5058.e19Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial characterization of single tumor cells by proteomics
Mund, Andreas & Mann, Matthias, 2022, In: Nature Biotechnology. 40, 8, p. 1186-1187 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Rapid and In-Depth Coverage of the (Phospho-)Proteome With Deep Libraries and Optimal Window Design for dia-PASEF
Skowronek, P., Thielert, Marvin Christoffer, Voytik, E., Tanzer, M. C., Hansen, F. M., Willems, S., Karayel, O., Brunner, A., Meier, F. & Mann, Matthias, 2022, In: Molecular and Cellular Proteomics. 21, 9, 15 p., 100279.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease
Karayel, O., Virreira Winter, S., Padmanabhan, S., Kuras, Y. I., Vu, D. T., Tuncali, I., Merchant, K., Wills, A. M., Scherzer, C. R. & Mann, Matthias, 2022, In: Cell Reports Medicine. 3, 6, 20 p., 100661.Research output: Contribution to journal › Journal article › Research › peer-review
Phosphorylation of serine-893 in CARD11 suppresses the formation and activity of the CARD11-BCL10-MALT1 complex in T and B cells
Kutzner, K., Woods, S., Karayel, O., Gehring, T., Yin, H., Flatley, A., Graß, C., Wimberger, N., Tofaute, M. J., Seeholzer, T., Feederle, R., Mann, Matthias & Krappmann, D., Mar 2022, In: Science Signaling. 15, 723, p. eabk3083Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation
Stafford, C. A., Gassauer, A. M., de Oliveira Mann, C. C., Tanzer, M. C., Fessler, E., Wefers, B., Nagl, D., Kuut, G., Sulek, K., Vasilopoulou, C., Schwojer, S. J., Wiest, A., Pfautsch, M. K., Wurst, W., Yabal, M., Fröhlich, T., Mann, Matthias, Gisch, N., Jae, L. T. & Hornung, V., 2022, In: Nature. 609, p. 590-596 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal
Schnoeder, T. M., Schwarzer, A., Jayavelu, A. K., Hsu, C-J., Kirkpatrick, J., Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S. A., Nafria, M., Jiang, L., Dai, Y-T., Chen, Z., Chen, S-J., Kellaway, S. G., Ptasinska, A., Ng, E. S. & 17 others, , 2022, In: Blood. 139, 7, p. 1080-1097 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
Diamanti, K., Cavalli, M., Pereira, M. J., Pan, G., Castillejo-López, C., Kumar, C., Mundt Madsen, Filip Oskar, Komorowski, J., Deshmukh, Atul Shahaji, Mann, Matthias, Korsgren, O., Eriksson, J. W. & Wadelius, C., 2022, In: Cell Reports Medicine. 3, 10, 21 p., 100763.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
OpenCell: Endogenous tagging for the cartography of human cellular organization
Cho, N. H., Cheveralls, K. C., Brunner, A. D., Kim, K., Michaelis, A. C., Raghavan, P., Kobayashi, H., Savy, L., Li, J. Y., Canaj, H., Kim, J. Y. S., Stewart, E. M., Gnann, C., McCarthy, F., Cabrera, J. P., Brunetti, R. M., Chhun, B. B., Dingle, G., Hein, M. Y., Huang, B. & 7 others, , 2022, In: Science. 375, 6585, eabi6983.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Noninvasive proteomic biomarkers for alcohol-related liver disease
Niu, Lili, Thiele, M., Geyer, P. E., Rasmussen, D. N., Webel, Henry, Santos, A., Gupta, R., Meier, F., Strauss, Maximilian, Kjaergaard, M., Lindvig, K., Jacobsen, S., Rasmussen, Simon, Hansen, Torben, Krag, A. & Mann, Matthias, 2022, In: Nature Medicine. 28, 6, p. 1277-1287 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mast cells in lung damage of COVID-19 autopsies: A descriptive study
Schaller, T., Märkl, B., Claus, R., Sholl, L., Hornick, J. L., Giannetti, M. P., Schweizer, L., Mann, Matthias & Castells, M., 2022, In: Allergy. 77, 7, p. 2237-2239 3 p.Research output: Contribution to journal › Comment/debate › Research
In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance
Wirth, A-K., Wange, L., Vosberg, S., Henrich, K-O., Rausch, C., Özdemir, E., Zeller, C. M., Richter, D., Feuchtinger, T., Kaller, M., Hermeking, H., Greif, P. A., Senft, D., Jurinovic, V., Bahrami, E., Jayavelu, A. K., Westermann, F., Mann, M., Enard, W., Herold, T. & 1 others, , 2022, In: Leukemia. 36, p. 2863-2874 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of early neurodegenerative pathways in progressive multiple sclerosis
Kaufmann, M., Schaupp, A. L., Sun, R., Coscia, F., Dendrou, C. A., Cortes, A., Kaur, G., Evans, H. G., Mollbrink, A., Navarro, J. F., Sonner, J. K., Mayer, C., DeLuca, G. C., Lundeberg, J., Matthews, P. M., Attfield, K. E., Friese, M. A., Mann, Matthias & Fugger, Lars, 2022, In: Nature Neuroscience. 25, p. 944-955Research output: Contribution to journal › Journal article › Research › peer-review
IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
Schmacke, N. A., O'Duill, F., Gaidt, M. M., Szymanska, I., Kamper, J. M., Schmid-Burgk, J. L., Mädler, S. C., Mackens-Kiani, T., Kozaki, T., Chauhan, D., Nagl, D., Stafford, C. A., Harz, H., Fröhlich, A. L., Pinci, F., Ginhoux, F., Beckmann, R., Mann, Matthias, Leonhardt, H. & Hornung, V., 2022, In: Immunity. 55, 12, p. 2271-2284.e7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HYPK promotes the activity of the Nα-acetyltransferase A complex to determine proteostasis of nonAc-X2/N-degron-containing proteins
Miklánková, P., Linster, E., Boyer, J., Weidenhausen, J., Mueller, J., Armbruster, L., Lapouge, K., De La Torre, C., Bienvenut, W., Sticht, C., Mann, Matthias, Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M., 2022, In: Science Advances. 8, 24, 14 p., eabn6153.Research output: Contribution to journal › Journal article › Research › peer-review
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF
Dichtl, S., Sanin, D. E., Koss, C. K., Willenborg, S., Petzold, A., Tanzer, M. C., Dahl, A., Kabat, A. M., Lindenthal, L., Zeitler, L., Satzinger, S., Strasser, A., Mann, Matthias, Roers, A., Eming, S. A., El Kasmi, K. C., Pearce, E. J. & Murray, P. J., Apr 2022, In: Life Science Alliance. 5, 4Research output: Contribution to journal › Journal article › Research › peer-review
Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons
Riemenschneider, H., Guo, Q., Bader, J., Frottin, F., Farny, D., Kleinberger, G., Haass, C., Mann, Matthias, Hartl, F. U., Baumeister, W., Hipp, M. S., Meissner, F., Fernández-Busnadiego, R. & Edbauer, D., 2022, In: EMBO Reports. 23, 6, e53890.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic human liver proteome atlas reveals functional insights into disease pathways
Niu, Lili, Geyer, P. E., Gupta, R., Santos, A., Meier, F., Doll, S., Albrechtsen, Nicolai Jacob Wewer, Klein, S., Ortiz, C., Uschner, F. E., Schierwagen, R., Trebicka, J. & Mann, Matthias, 2022, In: Molecular Systems Biology. 18, 5, 24 p., e10947.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5650809
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2009
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Activation of the ATR kinase by the RPA-binding protein ETAA1
Research output: Contribution to journal › Journal article › Research › peer-review
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515
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Region and cell-type resolved quantitative proteomic map of the human heart
Research output: Contribution to journal › Journal article › Research › peer-review
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498
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Revisiting biomarker discovery by plasma proteomics
Research output: Contribution to journal › Review › Research › peer-review
Published