Matthias Mann

Matthias Mann

Professor, head of research, Professor

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    ORCID: 0000-0003-1292-4799

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    1. Published

      Mitochondrial specialization revealed by single muscle fiber proteomics: focus on the Krebs cycle

      Schiaffino, S., Reggiani, C., Kostrominova, T. Y., Mann, Matthias & Murgia, M., Dec 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Suppl 4, p. 41-8 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    2. Published

      Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes

      Choudhary, Chunaram, Olsen, Jesper Velgaard, Brandts, C., Cox, J., Reddy, P. N. G., Böhmer, F. D., Gerke, V., Schmidt-Arras, D., Berdel, W. E., Müller-Tidow, C., Mann, Matthias & Serve, H., 2009, In: Molecular Cell. 36, 2, p. 326-39 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells

      Graham, B., Marcais, A., Dharmalingam, G., Carroll, T., Kanellopoulou, C., Graumann, J., Nesterova, T. B., Bermange, A., Brazauskas, P., Xella, B., Kriaucionis, S., Higgs, D. R., Brockdorff, N., Mann, Matthias, Fisher, A. G. & Merkenschlager, M., 10 May 2016, In: Stem Cell Reports. 6, 5, p. 635-642 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      MiT/TFEfactors controlER-phagy via transcriptional regulation ofFAM134B

      Cinque, L., De Leonibus, C., Iavazzo, M., Krahmer, N., Intartaglia, D., Salierno, F. G., De Cegli, R., Di Malta, C., Svelto, M., Lanzara, C., Maddaluno, M., Wanderlingh, L. G., Huebner, A. K., Cesana, M., Bonn, F., Polishchuk, E., Huebner, C. A., Conte, I., Dikic, I., Mann, M. & 4 others, Ballabio, A., Sacco, F., Grumati, P. & Settembre, C., 2020, In: EMBO Journal. 39, 17, 22 p., 105696.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

      Nordgaard, C., Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, Jan, Rönnstrand, L., Mann, Matthias & Moreira, José, 2019, In: Molecular Oncology. 13, 12, p. 2646-2662

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk

      Hart, P. C., Kenny, H. A., Grassl, N., Watters, K. M., Litchfield, L. M., Coscia, F., Blaženović, I., Ploetzky, L., Fiehn, O., Mann, Matthias, Lengyel, E. & Romero, I. L., 2019, In: Cell Reports. 29, 12, p. 4086-4098.e6

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

      Gao, A., Larsen, N., Sparks, J., Gallina, I., Mann, Matthias, Räschle, M., Walter, J. & Duxin, Julien, 2018, bioRxiv, 54 p.

      Research output: Working paper › Preprint › Research

    8. Published

      MaxQuant.Live enables global targeting of more than 25,000 peptides

      Wichmann, C., Meier, F., Virreira Winter, S., Brunner, A., Cox, J. & Mann, Matthias, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 982-994 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Mast cells in lung damage of COVID-19 autopsies: A descriptive study

      Schaller, T., Märkl, B., Claus, R., Sholl, L., Hornick, J. L., Giannetti, M. P., Schweizer, L., Mann, Matthias & Castells, M., 2022, In: Allergy. 77, 7, p. 2237-2239 3 p.

      Research output: Contribution to journal › Comment/debate › Research

    10. Published

      Mass-spectrometric exploration of proteome structure and function

      Aebersold, R. & Mann, Matthias, 15 Sep 2016, In: Nature. 537, 7620, p. 347-55 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

      Bassani-Sternberg, M., Pletscher-Frankild, S., Jensen, Lars Juhl & Mann, Matthias, Mar 2015, In: Molecular and Cellular Proteomics. 14, 3, p. 658-73 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Making single-cell proteomics biologically relevant

      Rosenberger, F. A., Thielert, Marvin Christoffer & Mann, Matthias, 2023, In: Nature Methods. 20, p. 320-323 4 p.

      Research output: Contribution to journal › Comment/debate › Research

    13. MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics

      Mortensen, P., Gouw, J. W., Olsen, Jesper Velgaard, Ong, S., Rigbolt, K. T. G., Bunkenborg, J., Cox, J., Foster, L. J., Heck, A. J. R., Blagoev, B., Andersen, J. S. & Mann, Matthias, Jan 2010, In: Journal of Proteome Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      MS-Based Proteomics of Body Fluids: The End of the Beginning

      Bader, J. M., Albrecht, V. & Mann, Matthias, 2023, In: Molecular and Cellular Proteomics. 22, 7, 18 p., 100577.

      Research output: Contribution to journal › Review › Research › peer-review

    15. MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes

      Zhang, Y., Zhang, Y., Adachi, J., Olsen, Jesper Velgaard, Shi, R., de Souza, G., Pasini, E., Foster, L. J., Macek, B., Zougman, A., Kumar, C., Wisniewski, J. R., Jun, W. & Mann, Matthias, Jan 2007, In: Nucleic Acids Research. 35, Database issue, p. D771-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis

      Hartl, M., Füßl, M., Boersema, P. J., Jost, J., Kramer, K., Bakirbas, A., Sindlinger, J., Plöchinger, M., Leister, D., Uhrig, G., Moorhead, G. B., Cox, J., Salvucci, M. E., Schwarzer, D., Mann, Matthias & Finkemeier, I., 2017, In: Molecular Systems Biology. 13, 10, 16 p., 949.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Lysine acetylation targets protein complexes and co-regulates major cellular functions

      Choudhary, Chunaram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Science. 325, 5942, p. 834-40 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Lysine acetylation in mitochondria: From inventory to function

      Hosp, F., Lassowskat, I., Santoro, V., De Vleesschauwer, D., Fliegner, D., Redestig, H., Mann, Matthias, Christian, S., Hannah, M. A. & Finkemeier, I., Mar 2017, In: Mitochondrion. 33, p. 58-71 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    19. Published

      Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics

      Kulak, N. A., Geyer, P. E. & Mann, Matthias, Apr 2017, In: Molecular and Cellular Proteomics. 16, 4, p. 694-705 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin

      Ghanawi, H., Hennlein, L., Zare, A., Bader, J., Salehi, S., Hornburg, D., Ji, C., Sivadasan, R., Drepper, C., Meissner, F., Mann, Matthias, Jablonka, S., Briese, M. & Sendtner, M., 2021, In: Nucleic Acids Symposium Series. 49, 21, p. 12284-12305 22 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

      Liwocha, J., Krist, D. T., van der Heden van Noort, G. J., Hansen, F. M., Truong, V. H., Karayel, O., Purser, N., Houston, D., Burton, N., Bostock, M. J., Sattler, M., Mann, Matthias, Harrison, J. S., Kleiger, G., Ovaa, H. & Schulman, B. A., Mar 2021, In: Nature Chemical Biology. 17, 3, p. 272-279 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

      Ngo, B., Kim, E., Osorio-Vasquez, V., Doll, S., Bustraan, S., Liang, R. J., Luengo, A., Davidson, S. M., Ali, A., Ferraro, G. B., Fischer, G. M., Eskandari, R., Kang, D. S., Ni, J., Plasger, A., Rajasekhar, V. K., Kastenhuber, E. R., Bacha, S., Sriram, R. K., Stein, B. D. & 20 others, Bakhoum, S. F., Snuderl, M., Cotzia, P., Healey, J. H., Mainolfi, N., Suri, V., Friedman, A., Manfredi, M., Sabatini, D. M., Jones, D. R., Yu, M., Zhao, J. J., Jain, R. K., Keshari, K. R., Davies, M. A., Vander Heiden, M. G., Hernando, E., Mann, Matthias, Cantley, L. C. & Pacold, M. E., 2020, In: Cancer Discovery. 10, 9, p. 1352-1373

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      LifeTime and improving European healthcare through cell-based interceptive medicine

      Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N., Kjems, J., Knoblich, J. A. & 31 others, Krabbe, G., Lichter, P., Linnarsson, S., Marine, J. C., Marioni, J. C., Marti-Renom, M. A., Netea, M. G., Nickel, D., Nollmann, M., Novak, H. R., Parkinson, H., Piccolo, S., Pinheiro, I., Pombo, A., Popp, C., Reik, W., Roman-Roman, S., Rosenstiel, P., Schultze, J. L., Stegle, O., Tanay, A., Testa, G., Thanos, D., Theis, F. J., Torres-Padilla, M. E., Valencia, A., Vallot, C., van Oudenaarden, A., Mann, Matthias, Nielsen, A. F. & LifeTime Community Working Groups, L. C. W. G., 2020, In: Nature. 587, 7834, p. 377-386 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling

      Nagao, H., Cai, W., Brandão, B. B., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Gattu, A. K., Pan, H., Dreyfuss, J. M., Thomas Wunderlich, F., Mann, Matthias & Ronald Kahn, C., 2023, In: Journal of Clinical Investigation. 133, 4, 18 p., e161472.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

      Kruse, T., Benz, C., Garvanska, D. H., Lindqvist, R., Mihalic, F., Coscia, F., Inturi, R., Sayadi, A., Simonetti, L., Nilsson, E., Ali, M., Kliche, J., Moliner Morro, A., Mund, A., Andersson, E., McInerney, G., Mann, M., Jemth, P., Davey, N. E., Överby, A. K. & 2 others, Nilsson, Jakob & Ivarsson, Y., 2021, In: Nature Communications. 12, 1, 13 p., 6761.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 5650809