Matthias Mann

Matthias Mann

Professor, head of research, Professor


  1. Published

    Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

    Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome

    Ripaud, L., Chumakova, V., Antonin, M., Hastie, A. R., Pinkert, S., Körner, R., Ruff, K. M., Pappu, R. V., Hornburg, D., Mann, Matthias, Hartl, F. U. & Hipp, M. S., 23 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 51, p. 18219-24 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Origins of mass spectrometry-based proteomics

    Mann, Matthias, Nov 2016, In: Nature Reviews. Molecular Cell Biology. 17, 11, p. 678

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis

    Krahmer, N., Najafi, B., Schueder, F., Quagliarini, F., Steger, M., Seitz, S., Kasper, R., Salinas, F., Cox, J., Uhlenhaut, N. H., Walther, T. C., Jungmann, R., Zeigerer, A., Borner, G. H. H. & Mann, Matthias, 2018, In: Developmental Cell. 47, 2, p. 205-221.E7

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

    Diamanti, K., Cavalli, M., Pereira, M. J., Pan, G., Castillejo-López, C., Kumar, C., Mundt Madsen, Filip Oskar, Komorowski, J., Deshmukh, Atul Shahaji, Mann, Matthias, Korsgren, O., Eriksson, J. W. & Wadelius, C., 2022, In: Cell Reports Medicine. 3, 10, 21 p., 100763.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Opinion: Advocating for science progress as a human right

    Porsdam Mann, Sebastian, Donders, Y., Mitchell, C., Bradley, V. J., Chou, M. F., Mann, Matthias, Church, G. & Porsdam, Helle, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. 10820-10823 4 p.

    Research output: Contribution to journalComment/debateCommunication

  7. Published

    OpenCell: Endogenous tagging for the cartography of human cellular organization

    Cho, N. H., Cheveralls, K. C., Brunner, A. D., Kim, K., Michaelis, A. C., Raghavan, P., Kobayashi, H., Savy, L., Li, J. Y., Canaj, H., Kim, J. Y. S., Stewart, E. M., Gnann, C., McCarthy, F., Cabrera, J. P., Brunetti, R. M., Chhun, B. B., Dingle, G., Hein, M. Y., Huang, B. & 7 others, Mehta, S. B., Weissman, J. S., Gómez-Sjöberg, R., Itzhak, D. N., Royer, L. A., Mann, Matthias & Leonetti, M. D., 2022, In: Science. 375, 6585, eabi6983.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Online parallel accumulation - serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer

    Meier, F., Brunner, A., Koch, S., Koch, H., Lubeck, M., Krause, M., Goedecke, N., Decker, J., Kosinski, T., Park, M. A., Bache, N., Hoerning, O., Cox, J., Räther, O. & Mann, Matthias, 2018, In: Molecular and Cellular Proteomics. 17, 12, p. 2534-2545

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

    Chheda, Z. S., Kohanbash, G., Okada, K., Jahan, N., Sidney, J., Pecoraro, M., Yang, X., Carrera, D. A., Downey, K. M., Shrivastav, S., Liu, S., Lin, Y., Lagisetti, C., Chuntova, P., Watchmaker, P. B., Mueller, S., Pollack, I. F., Rajalingam, R., Carcaboso, A. M., Mann, M. & 4 others, Sette, A., Garcia, K. C., Hou, Y. & Okada, H., Jan 2018, In: The Journal of Experimental Medicine. 215, 1, p. 141-157 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Noninvasive proteomic biomarkers for alcohol-related liver disease

    Niu, Lili, Thiele, M., Geyer, P. E., Rasmussen, D. N., Webel, Henry, Santos, A., Gupta, R., Meier, F., Strauss, Maximilian, Kjaergaard, M., Lindvig, K., Jacobsen, S., Rasmussen, Simon, Hansen, Torben, Krag, A. & Mann, Matthias, 2022, In: Nature Medicine. 28, 6, p. 1277-1287 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

    Knipscheer, P., van Dijk, W. J., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: EMBO Journal. 26, 11, p. 2797-807 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Neurodevelopmental deficits in human isogenic fragile x syndrome neurons

    Utami, K., Skotte, N. H., Colaco, A. R. -., Yusof, N. A. B. M., Sim, B., Yeo, X. Y., Bae, H., Garcia-Miralles, M., Radulescu, C., Jung, S., Mann, Matthias & Pouladi, M., 2019, In: Journal of Neurochemistry. 150, p. 103 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  13. Nanoelectrospray peptide mapping revisited: Composite survey spectra allow high dynamic range protein characterization without LCMS on an orbitrap mass spectrometer

    Lu, A., Waanders, L. F., Almeida, R., Li, G., Allen, M., Cox, J., Olsen, Jesper Velgaard, Bonaldi, T. & Mann, Matthias, 1 Dec 2007, In: International Journal of Mass Spectrometry. 268, 2-3, p. 158-167 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. N-linked glycosylation enrichment for in-depth cell surface proteomics of diffuse large B-cell lymphoma subtypes

    Deeb, S. J., Cox, J., Schmidt-Supprian, M. & Mann, Matthias, 4 Nov 2013, In: Molecular & Cellular Proteomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Myosin binding protein H-like (MYBPHL): a promising biomarker to predict atrial damage

    Lahm, H., Dressen, M., Beck, N., Doppler, S., Deutsch, M., Matsushima, S., Neb, I., Koenig, K. C., Sideris, K., Voss, S., Eschenbach, L., Puluca, N., Deisenhofer, I., Doll, S., Holdenrieder, S., Mann, Matthias, Lange, R. & Krane, M., 2019, In: Scientific Reports. 9, 8 p., 9986.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation

    Pünzeler, S., Link, S., Wagner, G., Keilhauer, E. C., Kronbeck, N., Spitzer, R. M., Leidescher, S., Markaki, Y., Mentele, E., Regnard, C., Schneider, K., Takahashi, D., Kusakabe, M., Vardabasso, C., Zink, L. M., Straub, T., Bernstein, E., Harata, M., Leonhardt, H., Mann, M. & 2 others, Rupp, R. A. & Hake, S. B., 1 Aug 2017, In: E M B O Journal. 36, 15, p. 2263-2279 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

    Stukalov, A., Girault, V., Grass, V., Karayel, O., Bergant, V., Urban, C., Haas, D. A., Huang, Y., Oubraham, L., Wang, A., Hamad, M. S., Piras, A., Hansen, F. M., Tanzer, M. C., Paron, I., Zinzula, L., Engleitner, T., Reinecke, M., Lavacca, T. M., Ehmann, R. & 10 others, Wölfel, R., Jores, J., Kuster, B., Protzer, U., Rad, R., Ziebuhr, J., Thiel, V., Scaturro, P., Mann, Matthias & Pichlmair, A., 12 Apr 2021, (E-pub ahead of print) In: Nature.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes

    Wigger, L., Barovic, M., Brunner, A-D., Marzetta, F., Schöniger, E., Mehl, F., Kipke, N., Friedland, D., Burdet, F., Kessler, C., Lesche, M., Thorens, B., Bonifacio, E., Legido-Quigley, C., Barbier Saint Hilaire, P., Delerive, P., Dahl, A., Klose, C., Gerl, M. J., Simons, K. & 7 others, Aust, D., Weitz, J., Distler, M., Schulte, A. M., Mann, Matthias, Ibberson, M. & Solimena, M., 28 Jun 2021, (E-pub ahead of print) In: Nature Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

    Yang, P., Humphrey, S. J., Cinghu, S., Pathania, R., Oldfield, A. J., Kumar, D., Perera, D., Yang, J. Y. H., James, D. E., Mann, Matthias & Jothi, R., 22 May 2019, In: Cell Systems. 8, 5, p. 427-445.e10

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

    Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S. D., López-Méndez, B., Nilsson, Jakob, Mund, Andreas, Mann, Matthias & Curtis, M., 2018, In: Cell. 175, 1, p. 159-170.e16

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics

    Franz, A., Coscia, F., Shen, C., Charaoui, L., Mann, Matthias & Sander, C., 2021, In: Journal of Ovarian Research. 14, 14 p., 140.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC

    Frey, F., Sheahan, T., Finkl, K., Stoehr, G., Mann, Matthias, Benda, C. & Müller, J., 1 May 2016, In: Genes & Development. 30, 9, p. 1116-27 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Molecular and structural architecture of polyQ aggregates in yeast

    Gruber, A., Hornburg, D., Antonin, M., Krahmer, N., Collado, J., Schaffer, M., Zubaite, G., Lüchtenborg, C., Sachsenheimer, T., Brügger, B., Mann, Matthias, Baumeister, W., Hartl, F. U., Hipp, M. S. & Fernández-Busnadiego, R., 2018, In: Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Molecular Origin of Blood-based Infrared Spectroscopic Fingerprints

    Voronina, L., Leonardo, C., Mueller-Reif, J. B., Geyer, P. E., Huber, M., Trubetskov, M., Kepesidis, K. V., Behr, J., Mann, Matthias, Krausz, F. & Žigman, M., 2021, In: Angewandte Chemie International Edition. 60, 31, p. 17060-17069

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Mobi-DIK (Ion Mobility DIA Analysis Kit): Targeted analysis software for diaPASEF data improves proteome coverage

    Ha, A., Frank, M., Meier, F., Brunner, A., Kaspar-Schoenefeld, S., Koch, S., Lubeck, M., Raether, O., Collins, B. C., Aebersold, R., Mann, Matthias & Rost, H., 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S17 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

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ID: 5650809