Matthias Mann

Matthias Mann

Professor, head of research, Professor

Member of:

    ORCID: 0000-0003-1292-4799

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    1. Published

      System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

      Rigbolt, K. T. G., Prokhorova, T., Akimov, V., Løkkegaard, Jeanette, Johansen, P. T., Kratchmarova, I., Kassem, M. S. E., Mann, Matthias, Olsen, Jesper Velgaard & Blagoev, B., 2011, In: Science Signaling. 4, 164, p. rs3

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity

      Riera-Tur, I., Schäfer, T., Hornburg, D., Mishra, A., da Silva Padilha, M., Fernández-Mosquera, L., Feigenbutz, D., Auer, P., Mann, Matthias, Baumeister, W., Klein, R., Meissner, F., Raimundo, N., Fernández-Busnadiego, R. & Dudanova, I., Mar 2022, In: Life Science Alliance. 5, 3

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons

      Riemenschneider, H., Guo, Q., Bader, J., Frottin, F., Farny, D., Kleinberger, G., Haass, C., Mann, Matthias, Hartl, F. U., Baumeister, W., Hipp, M. S., Meissner, F., Fernández-Busnadiego, R. & Edbauer, D., 2022, In: EMBO Reports. 23, 6, e53890.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Social network architecture of human immune cells unveiled by quantitative proteomics

      Rieckmann, J. C., Geiger, R., Hornburg, D., Wolf, T., Kveler, K., Jarrossay, D., Sallusto, F., Shen-Orr, S. S., Lanzavecchia, A., Mann, Matthias & Meissner, F., May 2017, In: Nature Immunology. 18, 5, p. 583-593 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry

      Reim, A., Ackermann, R., Font-Mateu, J., Kammel, R., Beato, M., Nolte, S., Mann, Matthias, Russmann, C. & Wierer, M., 15 Jun 2020, In: Nature Communications. 11, 1, p. 3019

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. SHP1 regulates a STAT6-ITGB3 axis in FLT3ITD-positive AML cells

      Reich, D., Kresinsky, A., Müller, J. P., Bauer, R., Kallenbach, J., Schnoeder, T. M., Heidel, F. H., Fässler, R., Mann, Matthias, Böhmer, F. & Jayavelu, A. K., 2020, In: Leukemia. 34, p. 1444-1449

      Research output: Contribution to journal › Letter › Research › peer-review

    7. Defective glycosylation and multisystem abnormalities characterize the primary immunodeficiency XMEN disease

      Ravell, J. C., Matsuda-Lennikov, M., Chauvin, S. D., Zou, J., Biancalana, M., Deeb, S. J., Price, S., Su, H. C., Notarangelo, G., Jiang, P., Morawski, A., Kanellopoulou, C., Binder, K. W., Mukherjee, R., Anibal, J. T., Sellers, B., Zheng, L., He, T., George, A. B., Pittaluga, S. & 34 others, Powers, A., Kleiner, D. E., Kapuria, D., Ghany, M., Hunsberger, S., Cohen, J. I., Uzel, G., Bergerson, J., Wolfe, L., Toro, C., Gahl, W., Folio, L. R., Matthews, H., Angelus, P., Chinn, I. K., Orange, J. S., Trujillo-Vargas, C. M., Franco, J. L., Orrego-Arango, J., Gutiérrez-Hincapié, S., Patel, N. C., Raymond, K., Patiroglu, T., Unal, E., Karakukcu, M., Day, A. G., Mehta, P., Masutani, E., De Ravin, S. S., Malech, H. L., Altan-Bonnet, G., Rao, V. K., Mann, Matthias & Lenardo, M. J., 5 Nov 2019, (E-pub ahead of print) In: The Journal of Clinical Investigation.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      LifeTime and improving European healthcare through cell-based interceptive medicine

      Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N., Kjems, J., Knoblich, J. A. & 31 others, Krabbe, G., Lichter, P., Linnarsson, S., Marine, J. C., Marioni, J. C., Marti-Renom, M. A., Netea, M. G., Nickel, D., Nollmann, M., Novak, H. R., Parkinson, H., Piccolo, S., Pinheiro, I., Pombo, A., Popp, C., Reik, W., Roman-Roman, S., Rosenstiel, P., Schultze, J. L., Stegle, O., Tanay, A., Testa, G., Thanos, D., Theis, F. J., Torres-Padilla, M. E., Valencia, A., Vallot, C., van Oudenaarden, A., Mann, Matthias, Nielsen, A. F. & LifeTime Community Working Groups, L. C. W. G., 2020, In: Nature. 587, 7834, p. 377-386 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

      Radovanac, K., Morgner, J., Schulz, J., Blumbach, K., Patterson, C., Geiger, T., Mann, Matthias, Krieg, T., Eckes, B., Fässler, R. & Wickström, S. A., 15 May 2013, In: E M B O Journal. 32, 10, p. 1409-24 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      D13 Saliva biomarker discovery in Huntington’s disease

      Qvist, Filippa Liliendahl, Hellem, M. N., Nielsen, Jørgen Erik, Mann, Matthias & Skotte, Niels Henning, 2022, In: Journal of Neurology, Neurosurgery and Psychiatry. 93, Suppl. 1, p. A24-A25

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    11. Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation

      Qiao, S., Lee, C., Sherpa, D., Chrustowicz, J., Cheng, J., Duennebacke, M., Steigenberger, B., Karayel, O., Vu, D. T., von Gronau, S., Mann, Matthias, Wilfling, F. & Schulman, B. A., 2022, In: Nature Communications. 13, 3041.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly

      Qiao, S., Langlois, C. R., Chrustowicz, J., Sherpa, D., Karayel, O., Hansen, F. M., Beier, V., von Gronau, S., Bollschweiler, D., Schäfer, T., Alpi, A. F., Mann, Matthias, Prabu, J. R. & Schulman, B. A., 1 Nov 2019, (E-pub ahead of print) In: Molecular Cell.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation

      Pünzeler, S., Link, S., Wagner, G., Keilhauer, E. C., Kronbeck, N., Spitzer, R. M., Leidescher, S., Markaki, Y., Mentele, E., Regnard, C., Schneider, K., Takahashi, D., Kusakabe, M., Vardabasso, C., Zink, L. M., Straub, T., Bernstein, E., Harata, M., Leonhardt, H., Mann, M. & 2 others, Rupp, R. A. & Hake, S. B., 1 Aug 2017, In: E M B O Journal. 36, 15, p. 2263-2279 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions

      Procida, T., Friedrich, T., Jack, A. P. M., Peritore, M., Bönisch, C., Eberl, H. C., Daus, N., Kletenkov, K., Nist, A., Stiewe, T., Borggrefe, T., Mann, Matthias, Bartkuhn, M. & Hake, S. B., 12 Jan 2021, In: International Journal of Molecular Sciences. 22, 2

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1

      Prestel, M., Prell-Schicker, C., Webb, T., Malik, R., Lindner, B., Ziesch, N., Rex-Haffner, M., Röh, S., Viturawong, T., Lehm, M., Mokry, M., den Ruijter, H., Haitjema, S., Asare, Y., Söllner, F., Najafabadi, M. G., Aherrahrou, R., Civelek, M., Samani, N. J., Mann, M. & 2 others, Haffner, C. & Dichgans, M., Oct 2019, In: Stroke. 50, 10, p. 2651-2660 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Alleles of a polymorphic ETV6 binding site in DCDC2 confer risk of reading and language impairment

      Powers, N. R., Eicher, J. D., Butter, F., Kong, Y., Miller, L. L., Ring, S. M., Mann, Matthias & Gruen, J. R., 11 Jul 2013, In: American Journal of Human Genetics. 93, 1, p. 19-28 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Opinion: Advocating for science progress as a human right

      Porsdam Mann, Sebastian, Donders, Y., Mitchell, C., Bradley, V. J., Chou, M. F., Mann, Matthias, Church, G. & Porsdam, Helle, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. 10820-10823 4 p.

      Research output: Contribution to journal › Comment/debate › Communication

    18. YBX1 mediates translation of oncogenic transcripts to control cell competition in AML

      Perner, F., Schnoeder, T. M., Xiong, Y., Jayavelu, A. K., Mashamba, N., Santamaria, N. T., Huber, N., Todorova, K., Hatton, C., Perner, B., Eifert, T., Murphy, C., Hartmann, M., Hoell, J. I., Schröder, N., Brandt, S., Hochhaus, A., Mertens, P. R., Mann, M., Armstrong, S. A. & 2 others, Mandinova, A. & Heidel, F. H., Feb 2022, In: Leukemia. 36, 2, p. 426-437 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins

      Pasini, E. M., Braks, J. A., Fonager, J., Klop, O., Aime, E., Spaccapelo, R., Otto, T. D., Berriman, M., Hiss, J. A., Thomas, A. W., Mann, Matthias, Janse, C. J., Kocken, C. H. M. & Franke-Fayard, B., Feb 2013, In: Molecular & Cellular Proteomics. 12, 2, p. 426-48 23 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Cohort profile: the MUNICH Preterm and Term Clinical study (MUNICH-PreTCl), a neonatal birth cohort with focus on prenatal and postnatal determinants of infant and childhood morbidity

      Pangratz-Fuehrer, S., Genzel-Boroviczény, O., Bodensohn, W. E., Eisenburger, R., Scharpenack, J., Geyer, P. E., Müller-Reif, J. B., van Hagen, N., Müller, A. M., Jensen, Majken Karoline, Klein, C., Mann, Matthias & Nussbaum, C., 2021, In: BMJ Open. 11, 6, 13 p., e050652.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics

      Pan, C., Olsen, Jesper Velgaard, Daub, H. & Mann, Matthias, 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2796-808 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors

      Pan, C., Gnad, F., Olsen, Jesper Velgaard & Mann, Matthias, 2008, In: Proteomics. 8, 21, p. 4534-46 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation

      Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Proceedings of the National Academy of Science of the United States of America. 101, 37, p. 13417-22 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain

      Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In: Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Higher-energy C-trap dissociation for peptide modification analysis

      Olsen, Jesper Velgaard, Macek, B., Lange, O., Makarov, A., Horning, S. & Mann, Matthias, 2007, In: Nature Methods. 4, 9, p. 709-12 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Quantitative proteomic profiling of membrane proteins from the mouse brain cortex, hippocampus, and cerebellum using the HysTag reagent: mapping of neurotransmitter receptors and ion channels

      Olsen, Jesper Velgaard, Nielsen, P. A., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2007, In: Brain Research. 1134, 1, p. 95-106 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Trypsin cleaves exclusively C-terminal to arginine and lysine residues

      Olsen, Jesper Velgaard, Ong, S. & Mann, Matthias, 2004, In: Molecular and Cellular Proteomics. 3, 6, p. 608-14 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

      Olsen, Jesper Velgaard, Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P. & Mann, Matthias, 2006, In: Cell. 127, 3, p. 635-48 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap

      Olsen, Jesper Velgaard, de Godoy, L. M. F., Li, G., Macek, B., Mortensen, P., Pesch, R., Makarov, A., Lange, O., Horning, S. & Mann, Matthias, 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 2010-21 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. A dual pressure linear ion trap orbitrap instrument with very high sequencing speed

      Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Status of large-scale analysis of post-translational modifications by mass spectrometry

      Olsen, Jesper Velgaard & Mann, Matthias, 1 Nov 2013, In: Molecular & Cellular Proteomics. 12, p. 3444-52

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Effective representation and storage of mass spectrometry-based proteomic data sets for the scientific community

      Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2011, In: Science Signaling. 4, 160, p. pe7

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

      Olsen, Jesper Velgaard, Vermeulen, M., Santamaria, A., Kumar, C., Miller, M. L., Jensen, Lars Juhl, Gnad, F., Cox, J., Jensen, T. S., Nigg, E. A., Brunak, Søren & Mann, Matthias, 2010, In: Science Signaling. 3, 104, p. ra3 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer

      Oberhuber, M., Pecoraro, M., Rusz, M., Oberhuber, G., Wieselberg, M., Haslinger, P., Gurnhofer, E., Schlederer, M., Limberger, T., Lagger, S., Pencik, J., Kodajova, P., Högler, S., Stockmaier, G., Grund-Gröschke, S., Aberger, F., Bolis, M., Theurillat, J-P., Wiebringhaus, R., Weiss, T. & 13 others, Haitel, A., Brehme, M., Wadsak, W., Griss, J., Mohr, T., Hofer, A., Jäger, A., Pollheimer, J., Egger, G., Koellensperger, G., Mann, Matthias, Hantusch, B. & Kenner, L., Apr 2020, In: Molecular Systems Biology. 16, 4, p. e9247

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      The forebrain synaptic transcriptome is organized by clocks but its proteome is driven by sleep

      Noya, S. B., Colameo, D., Brüning, F., Spinnler, A., Mircsof, D., Opitz, L., Mann, Matthias, Tyagarajan, S. K., Robles, M. S. & Brown, S. A., 2019, In: Science. 366, 6462, eaav2642 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification

      Notenboom, V., Hibbert, R. G., van Rossum-Fikkert, S. E., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: Nucleic Acids Research. 35, 17, p. 5819-30 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      A Standardized and Reproducible Workflow for Membrane Glass Slides in Routine Histology and Spatial Proteomics

      Nordmann, T. M., Schweizer, L., Metousis, A., Thielert, Marvin Christoffer, Rodriguez, E., Gjerdrum, Lise Mette Rahbek, Stadler, P., Bzorek, M., Mund, Andreas, Rosenberger, F. A. & Mann, Matthias, 2023, In: Molecular & cellular proteomics : MCP. 22, 10, 9 p., 100643.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

      Nordgaard, C., Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, Jan, Rönnstrand, L., Mann, Matthias & Moreira, José, 2019, In: Molecular Oncology. 13, 12, p. 2646-2662

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Proteomics in the Study of Liver Diseases

      Niu, Lili, Geyer, P. E. & Mann, Matthias, 2018, The Human Gut-Liver-Axis in Health and Disease. Krag, A. & Hansen, T. (eds.). Springer, p. 165-193

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    40. Published

      Noninvasive proteomic biomarkers for alcohol-related liver disease

      Niu, Lili, Thiele, M., Geyer, P. E., Rasmussen, D. N., Webel, Henry, Santos, A., Gupta, R., Meier, F., Strauss, Maximilian, Kjaergaard, M., Lindvig, K., Jacobsen, S., Rasmussen, Simon, Hansen, Torben, Krag, A. & Mann, Matthias, 2022, In: Nature Medicine. 28, 6, p. 1277-1287 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Quick and clean: Cracking sentences encoded in E. coli by LC-MS/MS, de novo sequencing, and dictionary search

      Niu, Lili & Mann, Matthias, 2019, In: EuPA Open Proteomics. 22-23, p. 30-35 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease

      Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    43. Published

      Dynamic human liver proteome atlas reveals functional insights into disease pathways

      Niu, Lili, Geyer, P. E., Gupta, R., Santos, A., Meier, F., Doll, S., Albrechtsen, Nicolai Jacob Wewer, Klein, S., Ortiz, C., Uschner, F. E., Schierwagen, R., Trebicka, J. & Mann, Matthias, 2022, In: Molecular Systems Biology. 18, 5, 24 p., e10947.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

      Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Defining NASH from a multi-omics systems biology perspective

      Niu, Lili, Sulek, K., Vasilopoulou, C. G., Santos, A., Albrechtsen, Nicolai Jacob Wewer, Rasmussen, Simon, Meier, F. & Mann, Matthias, 2021, In: Journal of Clinical Medicine. 10, 20, 22 p., 4673.

      Research output: Contribution to journal › Review › Research › peer-review

    46. Published

      Constructing a cell-type resolved human liver proteome atlas: THU-034

      Niu, Lili, Geyer, P. & Mann, Matthias, 2018, In: Journal of Hepatology. 68, p. S138-S139

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    47. Proteomic mapping of brain plasma membrane proteins

      Nielsen, P. A., Olsen, Jesper Velgaard, Podtelejnikov, A. V., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 402-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

      Ngo, B., Kim, E., Osorio-Vasquez, V., Doll, S., Bustraan, S., Liang, R. J., Luengo, A., Davidson, S. M., Ali, A., Ferraro, G. B., Fischer, G. M., Eskandari, R., Kang, D. S., Ni, J., Plasger, A., Rajasekhar, V. K., Kastenhuber, E. R., Bacha, S., Sriram, R. K., Stein, B. D. & 20 others, Bakhoum, S. F., Snuderl, M., Cotzia, P., Healey, J. H., Mainolfi, N., Suri, V., Friedman, A., Manfredi, M., Sabatini, D. M., Jones, D. R., Yu, M., Zhao, J. J., Jain, R. K., Keshari, K. R., Davies, M. A., Vander Heiden, M. G., Hernando, E., Mann, Matthias, Cantley, L. C. & Pacold, M. E., 2020, In: Cancer Discovery. 10, 9, p. 1352-1373

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. High performance computational analysis of large-scale proteome data sets to assess incremental contribution to coverage of the human genome

      Neuhauser, N., Nagaraj, N., McHardy, P., Zanivan, S., Scheltema, R., Cox, J. & Mann, Matthias, 7 Jun 2013, In: Journal of Proteome Research. 12, 6, p. 2858-68 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins

      Neufeld-Cohen, A., Robles, M. S., Aviram, R., Manella, G., Adamovich, Y., Ladeuix, B., Nir, D., Rousso-Noori, L., Kuperman, Y., Golik, M., Mann, Matthias & Asher, G., 22 Mar 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 12, p. E1673-82

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. E-pub ahead of print

      Comparative quantitative proteomic analysis of melanoma subtypes, nevus-associated melanoma, and corresponding nevi

      Naimy, S., Sølberg, J. B. K., Kuczek, D. E., Løvendorf, Marianne Bengtson, Bzorek, M., Litman, Thomas, Mund, Andreas, Gjerdrum, Lise Mette Rahbek, Clark, R. A., Mann, Matthias & Dyring-Andersen, Beatrice, 5 Jan 2024, (E-pub ahead of print) In: The Journal of Investigative Dermatology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Correction to Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation

      Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, Matthias, 2012, In: Journal of Proteome Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis

      Nagao, H., Jayavelu, A. K., Cai, W., Pan, H., Dreyfuss, J. M., Batista, T. M., Brandão, B. B., Mann, Matthias & Kahn, C. R., 4 Jan 2023, In: Nature Communications. 14, 1, p. 57

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

      Nagao, H., Cai, W., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Batista, T. M., Pan, H., Dreyfuss, J. M., Mann, Matthias & Kahn, C. R., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 17, e2019474118.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling

      Nagao, H., Cai, W., Brandão, B. B., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Gattu, A. K., Pan, H., Dreyfuss, J. M., Thomas Wunderlich, F., Mann, Matthias & Ronald Kahn, C., 2023, In: Journal of Clinical Investigation. 133, 4, 18 p., e161472.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns

      Müller-Reif, J. B., Hansen, F. M., Schweizer, L., Treit, P. V., Geyer, P. E. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 10 p., 100082.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      The proteome landscape of the kingdoms of life

      Müller, J. B., Geyer, P. E., Colaço, A. R., Treit, P. V., Strauss, M. T., Oroshi, M., Doll, S., Virreira Winter, S., Bader, J. M., Köhler, N., Theis, F., Santos, A. & Mann, Matthias, 2020, In: Nature. 582, p. 592-596

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging

      Murgia, M., Toniolo, L., Nagaraj, N., Ciciliot, S., Vindigni, V., Schiaffino, S., Reggiani, C. & Mann, Matthias, 13 Jun 2017, In: Cell Reports. 19, 11, p. 2396-2409 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Proteomics of Cytochrome c Oxidase-Negative versus -Positive Muscle Fiber Sections in Mitochondrial Myopathy

      Murgia, M., Tan, J., Geyer, P. E., Doll, S., Mann, Matthias & Klopstock, T., 2019, In: Cell Reports. 29, 12, p. 3825-3834 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Protein profile of fiber types in human skeletal muscle: a single-fiber proteomics study

      Murgia, M., Nogara, L., Baraldo, M., Reggiani, C., Mann, Matthias & Schiaffino, S., 2021, In: Skeletal Muscle. 11, 1, 19 p., 24.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Plasma proteome profiling of healthy subjects undergoing bed rest reveals unloading-dependent changes linked to muscle atrophy

      Murgia, M., Brocca, L., Monti, E., Franchi, M. V., Zwiebel, M., Steigerwald, S., Giacomello, E., Sartori, R., Zampieri, S., Capovilla, G., Gasparini, M., Biolo, G., Sandri, M., Mann, Matthias & Narici, M. V., 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, p. 439-451

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Single muscle fiber proteomics reveals unexpected mitochondrial specialization

      Murgia, M., Nagaraj, N., Deshmukh, Atul Shahaji, Zeiler, M., Cancellara, P., Moretti, I., Reggiani, C., Schiaffino, S. & Mann, Matthias, 1 Mar 2015, In: E M B O Reports. 16, 3, p. 387-95 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Foresight in clinical proteomics: current status, ethical considerations, and future perspectives

      Mundt Madsen, Filip Oskar, Albrechtsen, Nicolai Jacob Wewer, Porsdam Mann, Sebastian, Treit, P., Ghodgaonkar-Steger, M., O’Flaherty, M., Raijmakers, R., Vizcaíno, J. A., Heck, A. J. R. & Mann, Matthias, 2023, In: Open Research Europe. 3, 19 p., 59.

      Research output: Contribution to journal › Letter › Research › peer-review

    64. Published

      Spatial characterization of single tumor cells by proteomics

      Mund, Andreas & Mann, Matthias, 2022, In: Nature Biotechnology. 40, 8, p. 1186-1187 2 p.

      Research output: Contribution to journal › Comment/debate › Research

    65. Published

      Unbiased spatial proteomics with single-cell resolution in tissues

      Mund, Andreas, Brunner, A. & Mann, Matthias, 2022, In: Molecular Cell. 82, 12, p. 2335-2349 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    66. Published

      Deep Visual Proteomics defines single-cell identity and heterogeneity

      Mund, A., Coscia, F., Kriston, A., Hollandi, R., Kovács, F., Brunner, A-D., Migh, E., Schweizer, L., Santos, A., Bzorek, M., Naimy, S., Rahbek-Gjerdrum, L. M., Dyring-Andersen, B., Bulkescher, J., Lukas, C., Eckert, M. A., Lengyel, E., Gnann, C., Lundberg, E., Horvath, P. & 1 others, Mann, Matthias, 2022, In: Nature Biotechnology. 40, p. 1231-1240

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics

      Mortensen, P., Gouw, J. W., Olsen, Jesper Velgaard, Ong, S., Rigbolt, K. T. G., Bunkenborg, J., Cox, J., Foster, L. J., Heck, A. J. R., Blagoev, B., Andersen, J. S. & Mann, Matthias, Jan 2010, In: Journal of Proteome Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

      Mootha, V. K., Bunkenborg, J., Olsen, Jesper Velgaard, Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., Patterson, N., Lander, E. S. & Mann, Matthias, 2003, In: Cell. 115, 5, p. 629-40 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. IKAP: A heuristic framework for inference of kinase activities from Phosphoproteomics data

      Mischnik, M., Sacco, F., Cox, J., Schneider, H., Schäfer, M., Hendlich, M., Crowther, D., Mann, Matthias & Klabunde, T., 1 Feb 2016, In: Bioinformatics (Online). 32, 3, p. 424-31 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      HYPK promotes the activity of the Nα-acetyltransferase A complex to determine proteostasis of nonAc-X2/N-degron-containing proteins

      Miklánková, P., Linster, E., Boyer, J., Weidenhausen, J., Mueller, J., Armbruster, L., Lapouge, K., De La Torre, C., Bienvenut, W., Sticht, C., Mann, Matthias, Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M., 2022, In: Science Advances. 8, 24, 14 p., eabn6153.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      The social and structural architecture of the yeast protein interactome

      Michaelis, A. C., Brunner, A., Zwiebel, M., Meier, F., Strauss, Maximilian, Bludau, I. & Mann, Matthias, 2023, In: Nature. 624, 7990, p. 192-200 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      The emerging role of mass spectrometry-based proteomics in drug discovery

      Meissner, F., Geddes-McAlister, J., Mann, Matthias & Bantscheff, M., 2022, In: Nature Reviews Drug Discovery. 21, p. 637-654 18 p.

      Research output: Contribution to journal › Review › Research › peer-review

    73. Direct proteomic quantification of the secretome of activated immune cells

      Meissner, F., Scheltema, R. A., Mollenkopf, H. & Mann, Matthias, 26 Apr 2013, In: Science (New York, N.Y.). 340, 6131, p. 475-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      BoxCar acquisition method enables single-shot proteomics at a depth of 10,000 proteins in 100 minutes

      Meier, F., Geyer, P. E., Virreira Winter, S., Cox, J. & Mann, Matthias, 2018, In: Nature Methods. 15, 6, p. 440-448 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      diaPASEF: parallel accumulation-serial fragmentation combined with data-independent acquisition

      Meier, F., Brunner, A., Frank, M., Ha, A., Bludau, I., Voytik, E., Kaspar-Schoenefeld, S., Lubeck, M., Raether, O., Bache, N., Aebersold, R., Collins, B. C., Roest, H. L. & Mann, Matthias, 2020, In: Nature Methods. 17, 12, p. 1229-1236

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Deep learning the collisional cross sections of the peptide universe from a million experimental values

      Meier, F., Köhler, N. D., Brunner, A. D., Wanka, J. M. H., Voytik, E., Strauss, M. T., Theis, F. J. & Mann, Matthias, 2021, In: Nature Communications. 12, 12 p., 1185.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation - Serial Fragmentation (PASEF) in Proteomics

      Meier, F., Park, M. A. & Mann, Matthias, 17 Aug 2021, (E-pub ahead of print) In: Molecular and Cellular Proteomics. p. 100138

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Online parallel accumulation - serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer

      Meier, F., Brunner, A., Koch, S., Koch, H., Lubeck, M., Krause, M., Goedecke, N., Decker, J., Kosinski, T., Park, M. A., Bache, N., Hoerning, O., Cox, J., Räther, O. & Mann, Matthias, 2018, In: Molecular and Cellular Proteomics. 17, 12, p. 2534-2545

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Parallel accumulation - serial fragmentation combined with data-independent acquisition (diaPASEF)

      Meier, F., Brunner, A., Frank, M., Ha, A., Voytik, E., Kaspar-Schoenefeld, S., Lubeck, M., Raether, O., Aebersold, R., Collins, B. C., Roest, H. L. & Mann, Matthias, 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S17 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    80. Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells

      Mehta, S., Buyanbat, A., Kai, Y., Karayel, O., Goldman, S. R., Seruggia, D., Zhang, K., Fujiwara, Y., Donovan, K. A., Zhu, Q., Yang, H., Nabet, B., Gray, N. S., Mann, Matthias, Fischer, E. S., Adelman, K. & Orkin, S. H., 18 Aug 2022, In: Cell Chemical Biology. 29, 8, p. 1273-1287.e8

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers

      Mayr, C. H., Simon, L. M., Leuschner, G., Ansari, M., Schniering, J., Geyer, P. E., Angelidis, I., Strunz, M., Singh, P., Kneidinger, N., Reichenberger, F., Silbernagel, E., Böhm, S., Adler, H., Lindner, M., Maurer, B., Hilgendorff, A., Prasse, A., Behr, J., Mann, M. & 3 others, Eickelberg, O., Theis, F. J. & Schiller, H. B., 2021, In: EMBO Molecular Medicine. e12871.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics

      Marx, H., Lemeer, S., Schliep, J. E., Matheron, L., Mohammed, S., Cox, J., Mann, Matthias, Heck, A. J. R. & Kuster, B., Jun 2013, In: Nature Biotechnology. 31, 6, p. 557-64 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis

      Marinkovic, M., Fuoco, C., Sacco, F., Cerquone Perpetuini, A., Giuliani, G., Micarelli, E., Pavlidou, T., Petrilli, L. L., Reggio, A., Riccio, F., Spada, F., Vumbaca, S., Zuccotti, A., Castagnoli, L., Mann, Matthias, Gargioli, C. & Cesareni, G., Jun 2019, In: Life Science Alliance. 2, 3

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Inflammatory signaling in human tuberculosis granulomas is spatially organized

      Marakalala, M. J., Raju, R. M., Sharma, K., Zhang, Y. J., Eugenin, E. A., Prideaux, B., Daudelin, I. B., Chen, P., Booty, M. G., Kim, J. H., Eum, S. Y., Via, L. E., Behar, S. M., Barry, C. E., Mann, Matthias, Dartois, V. & Rubin, E. J., May 2016, In: Nature Medicine. 22, 5, p. 531-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      Ethical Principles, Constraints and Opportunities in Clinical Proteomics

      Porsdam Mann, Sebastian, Treit, P. V., Geyer, P. E., Omenn, G. S. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 14 p., 100046.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      The ever expanding scope of electrospray mass spectrometry-a 30 year journey

      Mann, Matthias, 2019, In: Nature Communications. 10, 3744.

      Research output: Contribution to journal › Comment/debate › Research

    87. Artificial intelligence for proteomics and biomarker discovery

      Mann, Matthias, Kumar, C., Zeng, W. & Strauss, M. T., 18 Aug 2021, In: Cell Systems. 12, 8, p. 759-770 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    88. Published

      The Origins of Organellar Mapping by Protein Correlation Profiling

      Mann, Matthias, 2020, In: Proteomics. 20, 23, 4 p., e1900330.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      Plenary Lecture Proteomics technologies for signaling, clinical applications

      Mann, Matthias, 2017, p. S62. 1 p.

      Research output: Contribution to conference › Conference abstract for conference › Research

    90. Published

      Development, use, application of novel TIMS-Tof system

      Mann, Matthias, 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S20 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    91. Origins of mass spectrometry-based proteomics

      Mann, Matthias, Nov 2016, In: Nature Reviews. Molecular Cell Biology. 17, 11, p. 678

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Proteomics for biomedicine: A half-completed journey

      Mann, Matthias, 1 Feb 2012, In: EMBO Molecular Medicine. 4, 2, p. 75-77 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      The Coming Age of Complete, Accurate, and Ubiquitous Proteomes

      Mann, Matthias, Kulak, N. A., Nagaraj, N. & Cox, J., 21 Feb 2013, In: Molecular Cell. 49, 4, p. 583-590 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Error-tolerant identification of peptides in sequence databases by peptide sequence tags

      Mann, Matthias & Wilm, M., 15 Dec 1994, In: Analytical Chemistry. 66, 24, p. 4390-9 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Phosphoproteins of the chicken eggshell calcified layer

      Mann, K., Olsen, Jesper Velgaard, Macek, B., Gnad, F. & Mann, Matthias, 2007, In: Proteomics. 7, 1, p. 106-15 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. The proteome of the calcified layer organic matrix of turkey (Meleagris gallopavo) eggshell

      Mann, K. & Mann, Matthias, 2013, In: Proteome Science. 11, 1, p. 40

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. In-depth proteomic analyses of (greenlip abalone) nacre and prismatic organic shell matrix

      Mann, K., Cerveau, N., Gummich, M., Fritz, M., Mann, Matthias & Jackson, D. J., 2018, In: Proteome Science. 16, p. 11

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Identification of new chicken egg proteins by mass spectrometry-based proteomic analysis

      Mann, K., Olsen, Jesper Velgaard, MaĉEk, B., Gnad, F. & Mann, Matthias, Jun 2008, In: World's Poultry Science Journal. 64, 2, p. 209-218 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Top-down protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer

      Macek, B., Waanders, L. F., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 949-58 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation

      Macek, B., Gnad, F., Soufi, B., Kumar, C., Olsen, Jesper Velgaard, Mijakovic, I. & Mann, Matthias, 2007, In: Molecular and Cellular Proteomics. 7, 2, p. 299-307 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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