Jiri Lukas

Jiri Lukas

Executive Director, Professor

Member of:


    1. 2016
    2. Published

      53BP1 fosters fidelity of homology-directed DNA repair

      Ochs, Fena, Somyajit, K., Altmeyer, M., Rask, M. D., Lukas, Jiri & Lukas, Claudia, Aug 2016, In: Nature Structural and Molecular Biology. 23, 8, p. 714-21 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks

      Sotiriou, S. K., Kamileri, I., Lugli, N., Evangelou, K., Da-Ré, C., Huber, F., Padayachy, L., Tardy, S., Nicati, N. L., Barriot, S., Ochs, Fena, Lukas, Claudia, Lukas, Jiri, Gorgoulis, V. G., Scapozza, L. & Halazonetis, T. D., 15 Dec 2016, In: Molecular Cell. 64, 6, p. 1127-1134 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Profiling DNA damage response following mitotic perturbations

      Pedersen, R. S., Karemore, G., Gudjónsson, Thorkell, Rask, M., Neumann, B., Hériché, J., Pepperkok, R., Ellenberg, J., Gerlich, D. W., Lukas, Jiri & Lukas, Claudia, 15 Dec 2016, In: Nature Communications. 7, 12 p., 13887.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. 2017
    6. Published

      Replication Catastrophe: When a Checkpoint Fails because of Exhaustion

      Toledo, L., Neelsen, K. J. & Lukas, Jiri, 15 Jun 2017, In: Molecular Cell. 66, 6, p. 735-749 15 p.

      Research output: Contribution to journalReviewResearchpeer-review

    7. Published

      Redox-sensitive alteration of replisome architecture safeguards genome integrity

      Somyajit, K., Gupta, R., Sedlackova, H., Neelsen, K. J., Ochs, Fena, Rask, M., Choudhary, Chunaram & Lukas, Jiri, 10 Nov 2017, In: Science. 358, 6364, p. 797-802 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. 2018
    9. Published

      DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

      Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, D., Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chunaram, 2018, In: Cell. 173, 4, p. 972-988

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy

      Bennetzen, M. V., Kosar, M., Bunkenborg, J., Payne, M. R., Bartkova, J., Lindström, M. S., Lukas, Jiri, Andersen, J. S., Bartek, J. & Larsen, D. H., 2018, In: Cell Cycle. 17, 17, p. 2146-2163

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability

      Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N. N., Glytsou, C., Pateras, I. S., Swain, U., Souliotis, V. L., Georgakilas, A. G., Geacintov, N., Scorrano, L., Lukas, C., Lukas, J., Livneh, Z., Lygerou, Z., Chowdhury, D., Sørensen, C. S., Bartek, J. & 1 others, Gorgoulis, V. G., 2018, In: Genome Biology (Online Edition). 19, p. 1-18 37.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. 2019
    13. Published

      53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage

      Spies, J., Lukas, Claudia, Somyajit, K., Rask, M., Lukas, Jiri & Neelsen, K. J., 2019, In: Nature Cell Biology. 21, p. 487-497

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Stabilization of chromatin topology safeguards genome integrity

      Ochs, Fena, Karemore, G., Miron, E., Brown, J., Sedlackova, H., Rask, M., Lampe, M., Buckle, V., Schermelleh, L., Lukas, Jiri & Lukas, Claudia, 2019, In: Nature. 574, 7779, p. 571-574 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. 2020
    16. Published

      Equilibrium between nascent and parental MCM proteins protects replicating genomes

      Sedlackova, H., Rask, M., Gupta, R., Choudhary, Chunaram, Somyajit, K. & Lukas, Jiri, 2020, In: Nature. 587, p. 297-302 34 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication

      Ercilla, A., Benada, Jan, Gadi, Sampath Amitash, Zonderland, Gijs, Baldi, G., Somyajit, K., Ochs, Fena, Costanzo, V., Lukas, Jiri & Toledo, L., 2020, In: Cell Reports. 30, 7, p. 2416-2429.e7 22 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. 2021
    19. Published

      Homologous recombination as a fundamental genome surveillance mechanism during dna replication

      Spies, J., Polasek-Sedlackova, H., Lukas, Jiri & Somyajit, K., 2021, In: Genes. 12, 12, 17 p., 1960.

      Research output: Contribution to journalReviewResearchpeer-review

    20. Published

      Homology-directed repair protects the replicating genome from metabolic assaults

      Somyajit, K., Spies, J., Coscia, F., Kirik, U., Rask, M., Lee, J., Neelsen, K. J., Mund, Andreas, Jensen, Lars Juhl, Paull, T. T., Mann, Matthias & Lukas, Jiri, 2021, In: Developmental Cell. 56, 4, p. 461-477.e7

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2022
    22. Published

      Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes

      Polasek-Sedlackova, H., Miller, Thomas, Krejci, J., Rask, M. B. & Lukas, Jiri, 2022, In: Nature Communications. 13, 11 p., 6090.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. 2023
    24. Published
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    ID: 37762642