Jiri Lukas

Jiri Lukas

Executive Director, Professor

Member of:


    1. 2013
    2. Published

      Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

      Jungmichel, S., Rosenthal, F., Altmeyer, M., Lukas, Jiri, Hottiger, M. O. & Nielsen, Michael Lund, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 272-285 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling

      Altmeyer, M., Toledo Lazaro, L. I., Gudjónsson, Thorkell, Grøfte, M., Rask, M., Lukas, Claudia, Akimov, V., Blagoev, B., Bartek, J. & Lukas, Jiri, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 206-220

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Guarding against Collateral Damage during Chromatin Transactions

      Altmeyer, M. & Lukas, Jiri, 20 Jun 2013, In: Cell. 153, 7, p. 1431-4 4 p.

      Research output: Contribution to journalReviewResearchpeer-review

    5. Published

      Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response

      Bennetzen, M., Andersen, J. S., Lasen, D. H., Dinant, C., Watanabe, S., Bartek, J. & Lukas, Jiri, 1 Jun 2013, In: Cell Cycle. 12, 11, p. 1688-1695 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Shielding broken DNA for a quick fix

      Lukas, Jiri & Lukas, Claudia, 8 Feb 2013, In: Science. 339, 6120, p. 652-653 2 p.

      Research output: Contribution to journalReviewResearchpeer-review

    7. Published

      To spread or not to spread - chromatin modifications in response to DNA damage

      Altmeyer, M. & Lukas, Jiri, 9 Jan 2013, In: Current Opinion in Genetics & Development. 23, 2, p. 156-165 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. 2012
    9. Published

      Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatment

      Oplustilova, L., Wolanin, K., Bartkova, J., Lukas, Jiri, Bartek, J., Lau, A., O'Connor, M. J., Mistrik, M., Korinkova, G., Simkova, D., Bouchal, J. & Lenobel, R., 15 Oct 2012, In: Cell Cycle. 11, 20, p. 3837-3850 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

      Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      LEDGF (p75) promotes DNA-end resection and homologous recombination

      Daugaard, M., Baude, A., Fugger, K., Povlsen, L. K., Beck, H., Sørensen, Claus Storgaard, Petersen, N. H. T., Sorensen, P. H. B., Lukas, Claudia, Bartek, J., Lukas, Jiri, Rohde, M. & Jaattela, Marja, Aug 2012, In: Nature Structural & Molecular Biology. 19, 8, p. 803-810 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Jiri Lukas: Visualizing genome integrity maintenance. Interview by Caitlin Sedwick

      Lukas, Jiri, 9 Jul 2012, In: Journal of Cell Biology. 198, 1, p. 4-5 2 p.

      Research output: Contribution to journalJournal articleCommunication

    13. CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination

      Falck, J., Forment, J. V., Coates, J., Mistrik, M., Lukas, Jiri, Bartek, J. & Jackson, S. P., Jun 2012, In: E M B O Reports. 13, 6, p. 561-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage

      Moudry, P., Lukas, Claudia, Macurek, L., Hanzlikova, H., Hodny, Z., Lukas, Jiri & Bartek, J., 15 Apr 2012, In: Cell Cycle. 11, 8, p. 1573-82 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

      Hamerlik, P., Lathia, J. D., Rasmussen, R., Wu, Q., Bartkova, J., Lee, M., Moudry, P., Bartek, J., Fischer, W., Lukas, Jiri, Rich, J. N. & Bartek, J., 12 Mar 2012, In: The Journal of Experimental Medicine. 209, 3, p. 507-20 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

      Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. 2011
    18. Published

      53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

      Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In: Nature Cell Biology. 13, 3, p. 243-53 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. 2010
    20. HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

      Bekker-Jensen, Simon Holst, Danielsen, J. M. R., Fugger, K., Gromova, I., Nerstedt, A., Bartek, J., Lukas, Jiri & Mailand, Niels, 2010, In: Nature Cell Biology. 12, 1, p. 80-6; sup pp 1-12

      Research output: Contribution to journalLetterResearchpeer-review

    21. 2009
    22. Published

      DNA repair: New tales of an old tail

      Lukas, Jiri & Bartek, J., 2009, In: Nature. 458, 7238, p. 581-3 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities

      Fugger, K., Mistrik, M., Danielsen, J. R., Dinant, C., Falck, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 186, 5, p. 655-63 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Low-dose DNA damage and replication stress responses quantified by optimized automated single-cell image analysis

      Mistrik, M., Oplustilova, L., Lukas, Jiri & Bartek, J., 2009, In: Cell Cycle. 8, 16, p. 2592-9 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection

      Carson, C. T., Orazio, N. I., Lee, D. V., Suh, J., Bekker-Jensen, Simon Holst, Araujo, F. D., Lakdawala, S. S., Lilley, C. E., Bartek, J., Lukas, Jiri & Weitzman, M. D., 2009, In: EMBO Journal. 28, 6, p. 652-62 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

      Marteijn, J. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Lans, H., Schwertman, P., Gourdin, A. M., Dantuma, N. P., Lukas, Jiri & Vermeulen, W., 2009, In: Journal of Cell Biology. 186, 6, p. 835-47 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

      Doil, C., Mailand, Niels, Bekker-Jensen, Simon Holst, Ménard, Patrice, Larsen, D. H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 2009, In: Cell. 136, 3, p. 435-46 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin

      Faustrup, H., Bekker-Jensen, Simon Holst, Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 184, 1, p. 13-9 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. 2008
    30. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

      Melander, F., Bekker-Jensen, Simon Holst, Falck, J., Bartek, J., Mailand, Niels & Lukas, Jiri, 21 Apr 2008, In: Journal of Cell Biology. 181, 2, p. 213-26 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      HCLK2 is required for activity of the DNA damage response kinase ATR

      Rendtlew Danielsen, J. M., Larsen, D. H., Schou, K. B., Freire, R., Falck, J., Bartek, J. & Lukas, Jiri, 2008, In: Journal of Biological Chemistry. 284, 7, p. 4140-7 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 37762642