Jiri Lukas

Jiri Lukas

Executive Director, Professor

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    ORCID: 0000-0001-9087-506X

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    1. Published

      To spread or not to spread - chromatin modifications in response to DNA damage

      Altmeyer, M. & Lukas, Jiri, 9 Jan 2013, In: Current Opinion in Genetics & Development. 23, 2, p. 156-165 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

      Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M. D., Streicher, W., Jungmichel, S., Nielsen, Michael Lund & Lukas, Jiri, 19 Aug 2015, In: Nature Communications. 6, p. 1-12 8088.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Guarding against Collateral Damage during Chromatin Transactions

      Altmeyer, M. & Lukas, Jiri, 20 Jun 2013, In: Cell. 153, 7, p. 1431-4 4 p.

      Research output: Contribution to journal › Review › Research › peer-review

    4. Published

      The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling

      Altmeyer, M., Toledo Lazaro, L. I., Gudjónsson, Thorkell, Grøfte, M., Rask, M., Lukas, Claudia, Akimov, V., Blagoev, B., Bartek, J. & Lukas, Jiri, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 206-220

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Repair of DNA double-strand breaks leaves heritable impairment to genome function

      Bantele, Susi, Mordini, Irene, Biran, Alva Ada, Alcaraz, N., Wenger, Alice, Krietenstein, Nils, Groth, Anja & Lukas, Jiri, 2023, bioRxiv, 47 p.

      Research output: Working paper › Preprint › Research

    6. Published

      DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

      Bartkova, J., Horejsí, Z., Koed, K., Krämer, A., Tort, F., Zieger, K., Guldberg, P., Sehested, M., Nesland, J. M., Lukas, Claudia, Ørntoft, T., Lukas, Jiri & Bartek, J., 14 Apr 2005, In: Nature. 434, 7035, p. 864-70 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

      Bekker-Jensen, Simon Holst, Danielsen, J. M. R., Fugger, K., Gromova, I., Nerstedt, A., Bartek, J., Lukas, Jiri & Mailand, Niels, 2010, In: Nature Cell Biology. 12, 1, p. 80-6; sup pp 1-12

      Research output: Contribution to journal › Letter › Research › peer-review

    8. Published

      Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks

      Bekker-Jensen, Simon Holst, Fugger, K., Danielsen, J. R., Gromova, I., Sehested, M., Celis, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 6 Jul 2007, In: Journal of Biological Chemistry. 282, 27, p. 19638-43 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response

      Bennetzen, M., Andersen, J. S., Lasen, D. H., Dinant, C., Watanabe, S., Bartek, J. & Lukas, Jiri, 1 Jun 2013, In: Cell Cycle. 12, 11, p. 1688-1695 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy

      Bennetzen, M. V., Kosar, M., Bunkenborg, J., Payne, M. R., Bartkova, J., Lindström, M. S., Lukas, Jiri, Andersen, J. S., Bartek, J. & Larsen, D. H., 2018, In: Cell Cycle. 17, 17, p. 2146-2163

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection

      Carson, C. T., Orazio, N. I., Lee, D. V., Suh, J., Bekker-Jensen, Simon Holst, Araujo, F. D., Lakdawala, S. S., Lilley, C. E., Bartek, J., Lukas, Jiri & Weitzman, M. D., 2009, In: EMBO Journal. 28, 6, p. 652-62 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research

      Celis, J. E., Gromov, P., Gromova, I., Moreira, J. M. A., Cabezón, T., Ambartsumian, N., Grigorian, M., Lukanidin, E., Thor Straten, P., Guldberg, P., Bartkova, J., Bartek, J., Lukas, J., Lukas, C., Lykkesfeldt, A., Jäättelä, M., Roepstorff, P., Bolund, L., Ørntoft, T. F., Brünner, N. & 5 others, Overgaard, J., Sandelin, K., Blichert-Toft, M., Mouridsen, H. & Rank, F. E., 2003, In: Molecular and Cellular Proteomics. 2, 6, p. 369-377 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      LEDGF (p75) promotes DNA-end resection and homologous recombination

      Daugaard, M., Baude, A., Fugger, K., Povlsen, L. K., Beck, H., Sørensen, Claus Storgaard, Petersen, N. H. T., Sorensen, P. H. B., Lukas, Claudia, Bartek, J., Lukas, Jiri, Rohde, M. & Jaattela, Marja, Aug 2012, In: Nature Structural & Molecular Biology. 19, 8, p. 803-810 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

      Doil, C., Mailand, Niels, Bekker-Jensen, Simon Holst, Ménard, Patrice, Larsen, D. H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 2009, In: Cell. 136, 3, p. 435-46 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication

      Ercilla, A., Benada, Jan, Gadi, Sampath Amitash, Zonderland, Gijs, Baldi, G., Somyajit, K., Ochs, Fena, Costanzo, V., Lukas, Jiri & Toledo, L., 2020, In: Cell Reports. 30, 7, p. 2416-2429.e7 22 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis

      Evangelou, K., Bartkova, J., Kotsinas, A., Pateras, I. S., Liontos, M., Velimezi, G., Kosar, M., Liloglou, T., Trougakos, I. P., Dyrskjot, L., Andersen, C. L., Papaioannou, M., Drosos, Y., Papafotiou, G., Hodny, Z., Sosa-Pineda, B., Wu, X-R., Klinakis, A., Ørntoft, T. F., Lukas, J. & 2 others, Bartek, J. & Gorgoulis, V. G., 1 Nov 2013, In: Cell Death and Differentiation. 20, 11, p. 1485-1497 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

      Falck, J., Mailand, Niels, Syljuåsen, R. G., Bartek, J. & Lukas, Jiri, 12 Apr 2001, In: Nature. 410, 6830, p. 842-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination

      Falck, J., Forment, J. V., Coates, J., Mistrik, M., Lukas, Jiri, Bartek, J. & Jackson, S. P., Jun 2012, In: E M B O Reports. 13, 6, p. 561-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin

      Faustrup, H., Bekker-Jensen, Simon Holst, Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 184, 1, p. 13-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities

      Fugger, K., Mistrik, M., Danielsen, J. R., Dinant, C., Falck, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 186, 5, p. 655-63 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability

      Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N. N., Glytsou, C., Pateras, I. S., Swain, U., Souliotis, V. L., Georgakilas, A. G., Geacintov, N., Scorrano, L., Lukas, C., Lukas, J., Livneh, Z., Lygerou, Z., Chowdhury, D., Sørensen, C. S., Bartek, J. & 1 others, Gorgoulis, V. G., 2018, In: Genome Biology (Online Edition). 19, p. 1-18 37.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint.

      Groth, Anja, Lukas, Jiri, Nigg, E., Silljé, H., Wernstedt, C., Bartek, J. & Hansen, K., Apr 2003, In: The EMBO Journal. 22, 7, p. 1676-1687

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

      Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

      Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, D., Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chunaram, 2018, In: Cell. 173, 4, p. 972-988

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

      Hamerlik, P., Lathia, J. D., Rasmussen, R., Wu, Q., Bartkova, J., Lee, M., Moudry, P., Bartek, J., Fischer, W., Lukas, Jiri, Rich, J. N. & Bartek, J., 12 Mar 2012, In: The Journal of Experimental Medicine. 209, 3, p. 507-20 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 37762642