Jiri Lukas

Jiri Lukas

Executive Director, Professor

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    ORCID: 0000-0001-9087-506X

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    1. Published

      Equilibrium between nascent and parental MCM proteins protects replicating genomes

      Sedlackova, H., Rask, M., Gupta, R., Choudhary, Chunaram, Somyajit, K. & Lukas, Jiri, 2020, In: Nature. 587, p. 297-302 34 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      E2F activity is essential for survival of Myc-overexpressing human cancer cells

      Santoni Rugiu, Eric, Duro, D., Farkas, T., Mathiasen, I. S., Jäättelä, M., Bartek, J. & Lukas, Jiri, 2002, In: Oncogene. 21, 42, p. 6498-6509 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

      Santoni Rugiu, Eric, Falck, J., Mailand, Niels, Bartek, J. & Lukas, Jiri, May 2000, In: Molecular and Cellular Biology. 20, 10, p. 3497-509 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      HCLK2 is required for activity of the DNA damage response kinase ATR

      Rendtlew Danielsen, J. M., Larsen, D. H., Schou, K. B., Freire, R., Falck, J., Bartek, J. & Lukas, Jiri, 2008, In: Journal of Biological Chemistry. 284, 7, p. 4140-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes

      Polasek-Sedlackova, H., Miller, Thomas, Krejci, J., Rask, M. B. & Lukas, Jiri, 2022, In: Nature Communications. 13, 11 p., 6090.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Profiling DNA damage response following mitotic perturbations

      Pedersen, R. S., Karemore, G., Gudjónsson, Thorkell, Rask, M., Neumann, B., Hériché, J., Pepperkok, R., Ellenberg, J., Gerlich, D. W., Lukas, Jiri & Lukas, Claudia, 15 Dec 2016, In: Nature Communications. 7, 12 p., 13887.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatment

      Oplustilova, L., Wolanin, K., Bartkova, J., Lukas, Jiri, Bartek, J., Lau, A., O'Connor, M. J., Mistrik, M., Korinkova, G., Simkova, D., Bouchal, J. & Lenobel, R., 15 Oct 2012, In: Cell Cycle. 11, 20, p. 3837-3850 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Stabilization of chromatin topology safeguards genome integrity

      Ochs, Fena, Karemore, G., Miron, E., Brown, J., Sedlackova, H., Rask, M., Lampe, M., Buckle, V., Schermelleh, L., Lukas, Jiri & Lukas, Claudia, 2019, In: Nature. 574, 7779, p. 571-574 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      53BP1 fosters fidelity of homology-directed DNA repair

      Ochs, Fena, Somyajit, K., Altmeyer, M., Rask, M. D., Lukas, Jiri & Lukas, Claudia, Aug 2016, In: Nature Structural and Molecular Biology. 23, 8, p. 714-21 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

      Moudry, P., Watanabe, K., Wolanin, K. M., Bartkova, J., Wassing, I. E., Watanabe, S., Strauss, R., Pedersen, R. T., Østergaard, Vibe Hallundbæk, Lisby, Michael, Andújar-Sánchez, M., Maya-Mendoza, A., Esashi, F., Lukas, Jiri & Bartek, J., 2016, In: The Journal of Cell Biology. 212, 3, p. 281-288 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 37762642