Jiri Lukas
Executive Director, Professor
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The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis
Evangelou, K., Bartkova, J., Kotsinas, A., Pateras, I. S., Liontos, M., Velimezi, G., Kosar, M., Liloglou, T., Trougakos, I. P., Dyrskjot, L., Andersen, C. L., Papaioannou, M., Drosos, Y., Papafotiou, G., Hodny, Z., Sosa-Pineda, B., Wu, X-R., Klinakis, A., Ørntoft, T. F., Lukas, J. & 2 others, , 1 Nov 2013, In: Cell Death and Differentiation. 20, 11, p. 1485-1497 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
Ercilla, A., Benada, Jan, Gadi, Sampath Amitash, Zonderland, Gijs, Baldi, G., Somyajit, K., Ochs, Fena, Costanzo, V., Lukas, Jiri & Toledo, L., 2020, In: Cell Reports. 30, 7, p. 2416-2429.e7 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
Doil, C., Mailand, Niels, Bekker-Jensen, Simon Holst, Ménard, Patrice, Larsen, D. H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 2009, In: Cell. 136, 3, p. 435-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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LEDGF (p75) promotes DNA-end resection and homologous recombination
Daugaard, M., Baude, A., Fugger, K., Povlsen, L. K., Beck, H., Sørensen, Claus Storgaard, Petersen, N. H. T., Sorensen, P. H. B., Lukas, Claudia, Bartek, J., Lukas, Jiri, Rohde, M. & Jaattela, Marja, Aug 2012, In: Nature Structural & Molecular Biology. 19, 8, p. 803-810 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research
Celis, J. E., Gromov, P., Gromova, I., Moreira, J. M. A., Cabezón, T., Ambartsumian, N., Grigorian, M., Lukanidin, E., Thor Straten, P., Guldberg, P., Bartkova, J., Bartek, J., Lukas, J., Lukas, C., Lykkesfeldt, A., Jäättelä, M., Roepstorff, P., Bolund, L., Ørntoft, T. F., Brünner, N. & 5 others, , 2003, In: Molecular and Cellular Proteomics. 2, 6, p. 369-377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection
Carson, C. T., Orazio, N. I., Lee, D. V., Suh, J., Bekker-Jensen, Simon Holst, Araujo, F. D., Lakdawala, S. S., Lilley, C. E., Bartek, J., Lukas, Jiri & Weitzman, M. D., 2009, In: EMBO Journal. 28, 6, p. 652-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy
Bennetzen, M. V., Kosar, M., Bunkenborg, J., Payne, M. R., Bartkova, J., Lindström, M. S., Lukas, Jiri, Andersen, J. S., Bartek, J. & Larsen, D. H., 2018, In: Cell Cycle. 17, 17, p. 2146-2163Research output: Contribution to journal › Journal article › Research › peer-review
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Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response
Bennetzen, M., Andersen, J. S., Lasen, D. H., Dinant, C., Watanabe, S., Bartek, J. & Lukas, Jiri, 1 Jun 2013, In: Cell Cycle. 12, 11, p. 1688-1695 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
Bekker-Jensen, Simon Holst, Danielsen, J. M. R., Fugger, K., Gromova, I., Nerstedt, A., Bartek, J., Lukas, Jiri & Mailand, Niels, 2010, In: Nature Cell Biology. 12, 1, p. 80-6; sup pp 1-12Research output: Contribution to journal › Letter › Research › peer-review
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Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks
Bekker-Jensen, Simon Holst, Fugger, K., Danielsen, J. R., Gromova, I., Sehested, M., Celis, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 6 Jul 2007, In: Journal of Biological Chemistry. 282, 27, p. 19638-43 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37762642
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TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity
Research output: Contribution to journal › Journal article › Research › peer-review
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175
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Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
Research output: Contribution to journal › Journal article › Research › peer-review
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155
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Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
Research output: Contribution to journal › Journal article › Research › peer-review
Published