Jiri Lukas

Jiri Lukas

Executive Director, Professor

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    ORCID: 0000-0001-9087-506X

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    1. Published

      DNA repair: New tales of an old tail

      Lukas, Jiri & Bartek, J., 2009, In: Nature. 458, 7238, p. 581-3 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy

      Bennetzen, M. V., Kosar, M., Bunkenborg, J., Payne, M. R., Bartkova, J., Lindström, M. S., Lukas, Jiri, Andersen, J. S., Bartek, J. & Larsen, D. H., 2018, In: Cell Cycle. 17, 17, p. 2146-2163

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology

      Lukas, Claudia, Bartkova, J., Latella, L., Falck, J., Mailand, Niels, Schroeder, T., Sehested, M., Lukas, Jiri & Bartek, J., 1 Jul 2001, In: Cancer Research. 61, 13, p. 4990-3 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

      Bartkova, J., Horejsí, Z., Koed, K., Krämer, A., Tort, F., Zieger, K., Guldberg, P., Sehested, M., Nesland, J. M., Lukas, Claudia, Ørntoft, T., Lukas, Jiri & Bartek, J., 14 Apr 2005, In: Nature. 434, 7035, p. 864-70 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

      Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, D., Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chunaram, 2018, In: Cell. 173, 4, p. 972-988

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

      Liu, S., Bekker-Jensen, Simon Holst, Mailand, Niels, Lukas, Claudia, Bartek, J. & Lukas, Jiri, 2006, In: Molecular and Cellular Biology. 26, 16, p. 6056-64 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

      Krämer, A., Mailand, Niels, Lukas, Claudia, Syljuåsen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. & Lukas, Jiri, Sep 2004, In: Nature Cell Biology. 6, 9, p. 884-91 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination

      Falck, J., Forment, J. V., Coates, J., Mistrik, M., Lukas, Jiri, Bartek, J. & Jackson, S. P., Jun 2012, In: E M B O Reports. 13, 6, p. 561-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

      Hamerlik, P., Lathia, J. D., Rasmussen, R., Wu, Q., Bartkova, J., Lee, M., Moudry, P., Bartek, J., Fischer, W., Lukas, Jiri, Rich, J. N. & Bartek, J., 12 Mar 2012, In: The Journal of Experimental Medicine. 209, 3, p. 507-20 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response

      Bennetzen, M., Andersen, J. S., Lasen, D. H., Dinant, C., Watanabe, S., Bartek, J. & Lukas, Jiri, 1 Jun 2013, In: Cell Cycle. 12, 11, p. 1688-1695 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      ATR-Chk1-APC/C-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

      Yamada, M., Watanabe, K., Mistrik, M., Vesela, E., Protivankova, I., Mailand, Niels, Lee, M. H., Masai, H., Lukas, Jiri & Bartek, J., 15 Nov 2013, In: Genes & Development. 27, 22, p. 2459-2472 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

      Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      A lncRNA to repair DNA

      Lukas, Jiri & Altmeyer, M., 2015, In: E M B O Reports. 16, 11, p. 1413-1414 2 p.

      Research output: Contribution to journal › Comment/debate › Research

    14. Published

      53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

      Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In: Nature Cell Biology. 13, 3, p. 243-53 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage

      Spies, J., Lukas, Claudia, Somyajit, K., Rask, M., Lukas, Jiri & Neelsen, K. J., 2019, In: Nature Cell Biology. 21, p. 487-497

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      53BP1 fosters fidelity of homology-directed DNA repair

      Ochs, Fena, Somyajit, K., Altmeyer, M., Rask, M. D., Lukas, Jiri & Lukas, Claudia, Aug 2016, In: Nature Structural and Molecular Biology. 23, 8, p. 714-21 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 37762642