STRING 8--a global view on proteins and their functional interactions in 630 organisms
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STRING 8--a global view on proteins and their functional interactions in 630 organisms. / Jensen, Lars Juhl; Kuhn, Michael; Stark, Manuel; Chaffron, Samuel; Creevey, Chris; Muller, Jean; Doerks, Tobias; Julien, Philippe; Roth, Alexander; Simonovic, Milan; Bork, Peer; von Mering, Christian.
In: Nucleic Acids Research, Vol. 37, No. suppl 1, 2008, p. D412-D416.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - STRING 8--a global view on proteins and their functional interactions in 630 organisms
AU - Jensen, Lars Juhl
AU - Kuhn, Michael
AU - Stark, Manuel
AU - Chaffron, Samuel
AU - Creevey, Chris
AU - Muller, Jean
AU - Doerks, Tobias
AU - Julien, Philippe
AU - Roth, Alexander
AU - Simonovic, Milan
AU - Bork, Peer
AU - von Mering, Christian
N1 - Keywords: Databases, Protein; Genomics; Multiprotein Complexes; Protein Interaction Mapping; Proteins; User-Computer Interface
PY - 2008
Y1 - 2008
N2 - Functional partnerships between proteins are at the core of complex cellular phenotypes, and the networks formed by interacting proteins provide researchers with crucial scaffolds for modeling, data reduction and annotation. STRING is a database and web resource dedicated to protein-protein interactions, including both physical and functional interactions. It weights and integrates information from numerous sources, including experimental repositories, computational prediction methods and public text collections, thus acting as a meta-database that maps all interaction evidence onto a common set of genomes and proteins. The most important new developments in STRING 8 over previous releases include a URL-based programming interface, which can be used to query STRING from other resources, improved interaction prediction via genomic neighborhood in prokaryotes, and the inclusion of protein structures. Version 8.0 of STRING covers about 2.5 million proteins from 630 organisms, providing the most comprehensive view on protein-protein interactions currently available. STRING can be reached at http://string-db.org/.
AB - Functional partnerships between proteins are at the core of complex cellular phenotypes, and the networks formed by interacting proteins provide researchers with crucial scaffolds for modeling, data reduction and annotation. STRING is a database and web resource dedicated to protein-protein interactions, including both physical and functional interactions. It weights and integrates information from numerous sources, including experimental repositories, computational prediction methods and public text collections, thus acting as a meta-database that maps all interaction evidence onto a common set of genomes and proteins. The most important new developments in STRING 8 over previous releases include a URL-based programming interface, which can be used to query STRING from other resources, improved interaction prediction via genomic neighborhood in prokaryotes, and the inclusion of protein structures. Version 8.0 of STRING covers about 2.5 million proteins from 630 organisms, providing the most comprehensive view on protein-protein interactions currently available. STRING can be reached at http://string-db.org/.
U2 - 10.1093/nar/gkn760
DO - 10.1093/nar/gkn760
M3 - Journal article
C2 - 18940858
VL - 37
SP - D412-D416
JO - Nucleic Acids Research
JF - Nucleic Acids Research
SN - 0305-1048
IS - suppl 1
ER -
ID: 20418871