Diego Iglesias Gato
Research consultant
Groth Group
Blegdamsvej 3B, 2200 København N
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REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
Svensson, C., Ceder, J., Iglesias Gato, Diego, Chuan, Y. C., Pang, S. T., Bjartell, A., Martinez, R. M., Bott, L., Helczynski, L., Ulmert, D., Wang, Y., Niu, Y., Collins, C. & Flores Morales, A., 2014, In: Nucleic Acids Research. 42, 2, p. 999-1015 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ubiquitin ligase Cullin5SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation
Paul, I., Batth, Tanveer Singh, Iglesias Gato, Diego, Al-Araimi, A., Al-Haddabi, I., Alkharusi, A., Norstedt, G., Olsen, Jesper Velgaard, Zadjali, F. & Flores-Morales, A., 2017, In: Scientific Reports. 7, 14 p., 42800.Research output: Contribution to journal › Journal article › Research › peer-review
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Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer
Lima, T. S., De Oliveira Souza, Luciano, Iglesias Gato, Diego, Elversang, J., Jørgensen, Flemming Steen, Kallunki, Tuula Anneli, Røder, Andreas, Brasso, K. & Moreira, José, 2022, In: Frontiers in Pharmacology. 13, 13 p., 869461.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Profiling of Docetaxel-Resistant Prostate Cancer Cells Identifies Multiple Mechanisms of Therapeutic Resistance
Lima, T. S., Iglesias Gato, Diego, De Oliveira Souza, Luciano, Stenvang, Jan, Lima, D. S., Røder, Andreas, Brasso, K. & Moreira, José, 2021, In: Cancers. 13, 19 p.Research output: Contribution to journal › Journal article › Research
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Predictive value of combined analysis of pro-NPY and ERG in localized prostate cancer
Kristensen, G., Røder, Andreas, Berg, K. D., Elversang, J., Iglesias Gato, Diego, Moreira, José, Toft, B. G. & Brasso, K., 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 10, p. 804-813Research output: Contribution to journal › Journal article › Research › peer-review
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YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth
Jiang, N., Ke, B., Hjort-Jensen, K., Iglesias Gato, Diego, Wang, Z., Chang, P., Zhao, Y., Niu, X., Wu, T., Peng, B., Jiang, M., Li, X., Shang, Z., Wang, Q., Chang, C., Flores-Morales, A. & Niu, Y., 2017, In: OncoTarget. 8, 70, p. 115054-115067 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth
Jiang, N., Hjorth-Jensen, K., Hekmat, O., Iglesias Gato, Diego, Kruse, Thomas, Wang, C., Wei, W., Ke, B., Yan, B., Niu, Y., Olsen, Jesper Velgaard & Flores Morales, A., 2015, In: Oncogene. 34, p. 2764–2776 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The proteome of prostate cancer bone metastasis reveals heterogeneity with prognostic implications
Iglesias Gato, Diego, Thysell, E., Tyanova, S., Crnalic, S., Santos, A., Lima, T. S., Geiger, T., Cox, J., Widmark, A., Bergh, A., Mann, Matthias, Flores-Morales, A. & Wikström, P., 1 Nov 2018, In: Clinical Cancer Research. 24, 21, p. 5433-5444 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo: [Plus] erratum
Iglesias Gato, Diego, Chuan, Y., Jiang, N., Lavallee, C., Bao, J., Paul, I., Egevad, L., Kessler, B. M., Wikström, P., Niu, Y. & Flores-Morales, A., 27 Jan 2015, In: Molecular Cancer. 14, 14 p., 8.Research output: Contribution to journal › Journal article › Research › peer-review
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The Proteome of Primary Prostate Cancer
Iglesias Gato, Diego, Wikström, P., Tyanova, S., Lavallee, C., Thysell, E., Carlsson, J., Hägglöf, C., Cox, J., Andrén, O., Stattin, P., Egevad, L., Widmark, A., Bjartell, A., Collins, C. C., Bergh, A., Geiger, T., Mann, Matthias & Flores-Morales, A., May 2016, In: European Urology. 69, 5, p. 942-952 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Androgen-independent effects of Serenoa repens extract (Prostasan®) on prostatic epithelial cell proliferation and inflammation
Iglesias Gato, Diego, Carsten, T., Vesterlund, M., Pousette, A., Schoop, R. & Norstedt, G., Feb 2012, In: Phytotherapy Research. 26, 2, p. 259-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae
Iglesias Gato, Diego, Martín-Marcos, P., Santos, M. A., Hinnebusch, A. G. & Tamame, M., Jan 2011, In: Genetics. 187, 1, p. 105-122 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
Anti-proliferative effects by Sabal serrulata (Prostasan (R)) on prostatic cell lines
Iglesias Gato, Diego, Pousette, A., Flores Morales, A., Norstedt, G. & Schoop, R., Jul 2009, In: Planta Medica. 75, 9, p. 985-985Research output: Contribution to journal › Journal article › Research
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SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer
Iglesias Gato, Diego, Chuan, Y. C., Wikström, P., Augsten, S., Jiang, N., Niu, Y., Seipel, A., Danneman, D., Vermeij, M., Fernandez-Perez, L., Jenster, G., Egevad, L., Norstedt, G. & Flores Morales, A., 2014, In: Carcinogenesis. 35, 1, p. 24-33Research output: Contribution to journal › Journal article › Research › peer-review
Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells
Iglesias Gato, Diego, Zheng, S., Flanagan, J. N., Jiang, L., Kittaka, A., Sakaki, T., Yamamoto, K., Itoh, T., Lebrasseur, N. K., Norstedt, G. & Chen, T. C., 2011, In: Journal of Steroid Biochemistry and Molecular Biology. 127, 3-5, p. 269-75 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability (vol 46, pg 9484, 2018)
Hjorth-Jensen, K., Maya-Mendoza, A., Dalgaard, Nanna, Sigurosson, J. O., Bartek, J., Iglesias Gato, Diego, Olsen, Jesper Velgaard & Flores-Morales, A., 2018, In: Nucleic Acids Symposium Series. 46, 18, p. 9891-9891Research output: Contribution to journal › Journal article › Research › peer-review
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SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability
Hjorth-Jensen, K., Maya-Mendoza, A., Dalgaard, Nanna, Sigurðsson, J. O., Bartek, J., Iglesias Gato, Diego, Olsen, Jesper Velgaard & Flores-Morales, A., 2018, In: Nucleic Acids Research. 46, 18, p. 9484-9495Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative Mass Spectrometry-Based Proteomic Profiling for Precision Medicine in Prostate Cancer
Flores-Morales, A. & Iglesias Gato, Diego, 2017, In: Frontiers in Oncology. 7, p. 1-8 00267.Research output: Contribution to journal › Review › Research › peer-review
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Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer
Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C. & 1 others, , 2019, In: Clinical Cancer Research. 25, 2, p. 1-15Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver
Fernández-Pérez, L., Santana-Farré, R., Mirecki-Garrido, M. D., García, I., Guerra, B., Mateo-Diaz, C., Iglesias Gato, Diego, Díaz-Chico, J. C., Flores Morales, A. & Díaz, M., 2014, In: P L o S One. 9, 19 p., e96305.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver
Fernández-Pérez, L., Guerra, B., Recio, C., Cabrera-Galván, J. J., García, I., De La Rosa, J. V., Castrillo, A., Iglesias Gato, Diego & Díaz, M., 2023, In: Frontiers in Endocrinology. 14, 24 p., 1266150.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth Hormone Receptor Signaling Pathways and its Negative Regulation by SOCS2
Fernández Pérez, L., Flores-Morales, A., Guerra, B., Díaz-Chico, J. C. & Iglesias Gato, Diego, Oct 2016, Restricted Growth: Clinical, Genetic and Molecular Aspects. del Carmen Cardenas- Aguayo, M. (ed.). InTechOpen, p. 125-145 21 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Comprehensive metabolomics analysis of prostate cancer tissue in relation to tumor aggressiveness and TMPRSS2-ERG fusion status
Dudka, I., Thysell, E., Lundquist, K., Antti, H., Iglesias Gato, Diego, Flores-Morales, A., Bergh, A., Wikstrom, P. & Grobner, G., 2020, In: B M C Cancer. 20, 17 p., 437.Research output: Contribution to journal › Journal article › Research › peer-review
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Ezrin mediates c-Myc actions in prostate cancer cell invasion
Chuan, Y. C., Iglesias Gato, Diego, Fernandez-Perez, L., Cedazo-Minguez, A., Pang, S., Norstedt, G., Pousette, A. & Flores-Morales, A., 2010, In: Oncogene. 29, 10, p. 1531-42 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase
Andresen, C. A., Smedegaard, S., Sylvestersen, K. B., Svensson, C., Iglesias Gato, Diego, Cazzamali, G., Nielsen, T. K., Nielsen, Michael Lund & Flores Morales, A., 24 Jan 2014, In: The Journal of Biological Chemistry. 289, 4, p. 2043-2054 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 32914384
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2006
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Lipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
274
downloads
The ubiquitin ligase Cullin5SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
232
downloads
YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth
Research output: Contribution to journal › Journal article › Research › peer-review
Published