Protocol for EHR laboratory data preprocessing and seasonal adjustment using R and RStudio
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Protocol for EHR laboratory data preprocessing and seasonal adjustment using R and RStudio. / Muse, Victorine P.; Brunak, Søren.
In: STAR Protocols, Vol. 5, No. 1, 102912, 2024.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Protocol for EHR laboratory data preprocessing and seasonal adjustment using R and RStudio
AU - Muse, Victorine P.
AU - Brunak, Søren
N1 - Publisher Copyright: © 2024 The Author(s)
PY - 2024
Y1 - 2024
N2 - Seasonality in laboratory healthcare data is associated with possible under- and overdiagnoses of patients in the clinic. Here, we present a protocol to analyze electronic health record data for seasonality patterns and adjust existing reference intervals for these changes using R software. We describe steps for preprocessing population-wide patient laboratory data into a single dataset. We then detail steps for defining strata, normalizing to median, and fitting data to selected functions. For complete details on the use and execution of this protocol, please refer to Muse et al. (2023).1
AB - Seasonality in laboratory healthcare data is associated with possible under- and overdiagnoses of patients in the clinic. Here, we present a protocol to analyze electronic health record data for seasonality patterns and adjust existing reference intervals for these changes using R software. We describe steps for preprocessing population-wide patient laboratory data into a single dataset. We then detail steps for defining strata, normalizing to median, and fitting data to selected functions. For complete details on the use and execution of this protocol, please refer to Muse et al. (2023).1
KW - Bioinformatics
KW - Health Sciences
KW - Systems biology
U2 - 10.1016/j.xpro.2024.102912
DO - 10.1016/j.xpro.2024.102912
M3 - Journal article
C2 - 38427569
AN - SCOPUS:85188201367
VL - 5
JO - STAR Protocols
JF - STAR Protocols
SN - 2666-1667
IS - 1
M1 - 102912
ER -
ID: 387833553