Comorbidity of migraine with ADHD in adults

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Comorbidity of migraine with ADHD in adults. / Hansen, Thomas Folkmann; Hoeffding, Louise K.; Kogelman, Lisette; Haspang, Thilde Marie; Ullum, Henrik; Sørensen, Erik; Erikstrup, Christian; Pedersen, Ole Birger; Nielsen, Kaspar René; Hjalgrim, Henrik; Paarup, Helene M; Werge, Thomas; Burgdorf, Kristoffer.

In: BMC Neurology, Vol. 18, No. 1, 147, 2018, p. 1-9.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hansen, TF, Hoeffding, LK, Kogelman, L, Haspang, TM, Ullum, H, Sørensen, E, Erikstrup, C, Pedersen, OB, Nielsen, KR, Hjalgrim, H, Paarup, HM, Werge, T & Burgdorf, K 2018, 'Comorbidity of migraine with ADHD in adults', BMC Neurology, vol. 18, no. 1, 147, pp. 1-9. https://doi.org/10.1186/s12883-018-1149-6

APA

Hansen, T. F., Hoeffding, L. K., Kogelman, L., Haspang, T. M., Ullum, H., Sørensen, E., Erikstrup, C., Pedersen, O. B., Nielsen, K. R., Hjalgrim, H., Paarup, H. M., Werge, T., & Burgdorf, K. (2018). Comorbidity of migraine with ADHD in adults. BMC Neurology, 18(1), 1-9. [147]. https://doi.org/10.1186/s12883-018-1149-6

Vancouver

Hansen TF, Hoeffding LK, Kogelman L, Haspang TM, Ullum H, Sørensen E et al. Comorbidity of migraine with ADHD in adults. BMC Neurology. 2018;18(1):1-9. 147. https://doi.org/10.1186/s12883-018-1149-6

Author

Hansen, Thomas Folkmann ; Hoeffding, Louise K. ; Kogelman, Lisette ; Haspang, Thilde Marie ; Ullum, Henrik ; Sørensen, Erik ; Erikstrup, Christian ; Pedersen, Ole Birger ; Nielsen, Kaspar René ; Hjalgrim, Henrik ; Paarup, Helene M ; Werge, Thomas ; Burgdorf, Kristoffer. / Comorbidity of migraine with ADHD in adults. In: BMC Neurology. 2018 ; Vol. 18, No. 1. pp. 1-9.

Bibtex

@article{35d804cd1e2c4e719d147877891d47e1,
title = "Comorbidity of migraine with ADHD in adults",
abstract = "BACKGROUND: Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of both diseases. Thus, the objective is to assess whether migraine (with and without visual disturbances) and ADHD are comorbid disorders.METHODS: Participants from the Danish Blood Donor Study (N = 26,456, age 18-65, 46% female) were assessed for migraine and ADHD using the ASRS ver 1.1 clinically validated questionnaire and self-reported migraine in a cross-sectional study. Logistic regression was used to examine the comorbidity between migraine and ADHD, and their associated endophenotypes.RESULTS: Migraine was strongly associated with ADHD (OR = 1.8, 95% CI = 1.5-2.1), (238/6152 vs 690/19,376). There was a significant interaction between age and gender, with comorbidity increasing with age and female sex. Post-hoc analysis showed that migraine with visual disturbance was generally associated with a marginally higher risk of ADHD and this was independent of ADHD endophenotypes.CONCLUSION: Migraine and ADHD were demonstrated to be comorbid disorders; the association with ADHD was most prominent for participants with migraine with visual disturbances. Future studies will elucidate which genetic and environmental factors contribute to migraine-ADHD comorbidity.",
author = "Hansen, {Thomas Folkmann} and Hoeffding, {Louise K.} and Lisette Kogelman and Haspang, {Thilde Marie} and Henrik Ullum and Erik S{\o}rensen and Christian Erikstrup and Pedersen, {Ole Birger} and Nielsen, {Kaspar Ren{\'e}} and Henrik Hjalgrim and Paarup, {Helene M} and Thomas Werge and Kristoffer Burgdorf",
year = "2018",
doi = "10.1186/s12883-018-1149-6",
language = "English",
volume = "18",
pages = "1--9",
journal = "BMC Neurology",
issn = "1471-2377",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Comorbidity of migraine with ADHD in adults

AU - Hansen, Thomas Folkmann

AU - Hoeffding, Louise K.

AU - Kogelman, Lisette

AU - Haspang, Thilde Marie

AU - Ullum, Henrik

AU - Sørensen, Erik

AU - Erikstrup, Christian

AU - Pedersen, Ole Birger

AU - Nielsen, Kaspar René

AU - Hjalgrim, Henrik

AU - Paarup, Helene M

AU - Werge, Thomas

AU - Burgdorf, Kristoffer

PY - 2018

Y1 - 2018

N2 - BACKGROUND: Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of both diseases. Thus, the objective is to assess whether migraine (with and without visual disturbances) and ADHD are comorbid disorders.METHODS: Participants from the Danish Blood Donor Study (N = 26,456, age 18-65, 46% female) were assessed for migraine and ADHD using the ASRS ver 1.1 clinically validated questionnaire and self-reported migraine in a cross-sectional study. Logistic regression was used to examine the comorbidity between migraine and ADHD, and their associated endophenotypes.RESULTS: Migraine was strongly associated with ADHD (OR = 1.8, 95% CI = 1.5-2.1), (238/6152 vs 690/19,376). There was a significant interaction between age and gender, with comorbidity increasing with age and female sex. Post-hoc analysis showed that migraine with visual disturbance was generally associated with a marginally higher risk of ADHD and this was independent of ADHD endophenotypes.CONCLUSION: Migraine and ADHD were demonstrated to be comorbid disorders; the association with ADHD was most prominent for participants with migraine with visual disturbances. Future studies will elucidate which genetic and environmental factors contribute to migraine-ADHD comorbidity.

AB - BACKGROUND: Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of both diseases. Thus, the objective is to assess whether migraine (with and without visual disturbances) and ADHD are comorbid disorders.METHODS: Participants from the Danish Blood Donor Study (N = 26,456, age 18-65, 46% female) were assessed for migraine and ADHD using the ASRS ver 1.1 clinically validated questionnaire and self-reported migraine in a cross-sectional study. Logistic regression was used to examine the comorbidity between migraine and ADHD, and their associated endophenotypes.RESULTS: Migraine was strongly associated with ADHD (OR = 1.8, 95% CI = 1.5-2.1), (238/6152 vs 690/19,376). There was a significant interaction between age and gender, with comorbidity increasing with age and female sex. Post-hoc analysis showed that migraine with visual disturbance was generally associated with a marginally higher risk of ADHD and this was independent of ADHD endophenotypes.CONCLUSION: Migraine and ADHD were demonstrated to be comorbid disorders; the association with ADHD was most prominent for participants with migraine with visual disturbances. Future studies will elucidate which genetic and environmental factors contribute to migraine-ADHD comorbidity.

U2 - 10.1186/s12883-018-1149-6

DO - 10.1186/s12883-018-1149-6

M3 - Journal article

C2 - 30322380

VL - 18

SP - 1

EP - 9

JO - BMC Neurology

JF - BMC Neurology

SN - 1471-2377

IS - 1

M1 - 147

ER -

ID: 203893946