Tugce Karaderi
Assistant Professor, Visiting professor
Center for Health Data Science
Blegdamsvej 3, 2200 København N., 06 Bygning 6, Building: 06-2-20
Brunak Group
Blegdamsvej 3B
2200 København N
Member of:
- 2023
- Published
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits
Brown, A. A., Fernandez-Tajes, J. J., Hong, M. G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T. D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T., Hansen, T. H. & 134 others, , 2023, In: Nature Communications. 14, 17 p., 5062.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A saturated map of common genetic variants associated with human height
Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, , 2022, In: Nature. 610, p. 704–712Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational Models for Clinical Applications in Personalized Medicine - Guidelines and Recommendations for Data Integration and Model Validation
Collin, C. B., Gebhardt, T., Golebiewski, M., Karaderi, Tugce, Hillemanns, M., Khan, F. M., Salehzadeh-Yazdi, A., Kirschner, M., Krobitsch, S. & Kuepfer, L., 2022, In: Journal of Personalized Medicine. 12, 2, 24 p., 166.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Joint Investigation of 2-Month Post-diagnosis IgG Antibody Levels and Psychological Measures for Assessing Longer Term Multi-Faceted Recovery Among COVID-19 Cases in Northern Cyprus
Barin, B., Yoldascan, B. E., Savaskan, F., Ozbalikci, G., Karaderi, Tugce & Çakal, H., 2021, In: Frontiers in Public Health. 8, 9 p., 590096.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
A polygenic and phenotypic risk prediction for polycystic ovary syndrome evaluated by phenomewide association studies
Joo, Y. Y., Actkins, KE., Pacheco, J. A., Basile, A. O., Carroll, R., Crosslin, D. R., Day, F., Denny, J. C., Edwards, D. R. V., Hakonarson, H., Harley, J. B., Hebbring, S. J., Ho, K., Jarvik, G. P., Jones, M., Karaderi, T., Mentch, F. D., Meun, C., Namjou, B., Pendergrass, S. & 9 others, , 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 6, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
Yaghootkar, H., Zhang, Y., Spracklen, C. N., Karaderi, T., Huang, L. O., Bradfield, J., Schurmann, C., Fine, R. S., Preuss, M. H., Kutalik, Z., Wittemans, L. B., Lu, Y., Metz, S., Willems, S. M., Li-Gao, R., Grarup, N., Wang, S., Molnos, S., Sandoval-Zárate, A. A., Nalls, M. A. & 32 others, , 2020, In: Diabetes. 69, 11, 93 p.Research output: Contribution to journal › Journal article › Research › peer-review
Genome-wide methylation profiling in granulosa lutein cells of women with polycystic ovary syndrome (PCOS)
Makrinou, E., Drong, A. W., Christopoulos, G., Lerner, A., Chapa-Chorda, I., Karaderi, Tugce, Lavery, S., Hardy, K., Lindgren, C. M. & Franks, S., 2020, In: Molecular and Cellular Endocrinology. 500, 110611.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Host Genetics at the Intersection of Autoimmunity and COVID-19: A Potential Key for Heterogeneous COVID-19 Severity
Karaderi, Tugce, Bareke, H., Kunter, I., Seytanoglu, A., Cagnan, I., Balci, D., Barin, B., Hocaoglu, M. B., Rahmioglu, N., Asilmaz, E. & Taneri, B., 2020, In: Frontiers in Immunology. 11, 10 p., 586111.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Cyprus Women's Health Research (COHERE) initiative: determining the relative burden of women's health conditions and related co-morbidities in an Eastern Mediterranean population
Hocaoglu, M. B., Gurkas, S., Karaderi, Tugce, Taneri, B., Erguler, K., Barin, B., Bilgin, E. M., Eralp, G., Allison, M., Findikli, N., Boynukalin, K., Bahceci, M., Naci, H., Vincent, K., Missmer, S. A., Becker, C. M., Zondervan, K. T. & Rahmioglu, N., 2019, In: BMC Women's Health. 19, 7 p., 50.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology: [incl. correction]
Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I. & 31 others, , 2019, In: American Journal of Human Genetics. 105, 1, p. 15-28 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V. & 31 others, , 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediction of pancreatic fat and analysis of its determining factors using multi-omics datasets: an IMI DIRECTstudy
Karaderi, Tugce, Mazzoni, G., Brorsson, C., Westergaard, David, Banasik, Karina, Koivula, R., Thomas, L., Bell, J., Franks, P., Pearson, E. & Brunak, Søren, 2019, In: Diabetologia. 62, p. S166-S166Research output: Contribution to journal › Conference abstract in journal › Research
The severity of ankylosing spondylitis and responses to anti-tumour necrosis factor biologics are not influenced by the tumour necrosis factor receptor polymorphism incriminated in multiple sclerosis
Watts, L., Karaderi, Tugce, Roberts, A., Appleton, L., Wordsworth, T., Cohen, C., Wordsworth, P. & Vecellio, M., 2019, In: Genes and Immunity. 20, p. 167-171 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria
Day, F., Karaderi, T., Jones, M. R., Meun, C., He, C., Drong, A., Kraft, P., Lin, N., Huang, H., Broer, L., Magi, R., Saxena, R., Laisk, T., Urbanek, M., Hayes, M. G., Thorleifsson, G., Fernandez-Tajes, J., Mahajan, A., Mullin, B. H., Stuckey, B. G. A. & 30 others, , 2018, In: PLOS Genetics. 14, 12, 20 p., e1007813.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Rare and low-frequency coding variants alter human adult height
Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, , 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Sexual dimorphisms in genetic loci linked to body fat distribution
Pulit, S. L., Karaderi, Tugce & Lindgren, C. M., 2017, In: Bioscience Reports. 37, 1, BSR20160184.Research output: Contribution to journal › Review › Research › peer-review
- 2016
Testing the role of predicted gene knockouts in human anthropometric trait variation
NHLBI GO Exome Sequence Project, N. G. E. S. P., GOT2D, G., T2D-GENES, T. & GIANT Consortium, G. C., 15 May 2016, In: Human Molecular Genetics. 25, 10, p. 2082-2092 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Insights into the Genetic Susceptibility to Type 2 Diabetes from Genome-Wide Association Studies of Obesity-Related Traits
Karaderi, Tugce, Drong, A. W. & Lindgren, C. M., 22 Oct 2015, In: Current Diabetes Reports. 15, 10, 83.Research output: Contribution to journal › Review › Research › peer-review
Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations
Hayes, M. G., Urbanek, M., Ehrmann, D. A., Armstrong, L. L., Lee, J. Y., Sisk, R., Karaderi, T., Barber, T. M., McCarthy, M. I., Franks, S., Lindgren, C. M., Welt, C. K., Diamanti-Kandarakis, E., Panidis, D., Goodarzi, M. O., Azziz, R., Zhang, Y., James, R. G., Olivier, M., Kissebah, A. H. & 30 others, , 18 Aug 2015, In: Nature Communications. 6, 7502.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2)
Karaderi, Tugce, Keidel, S. M., Pointon, J. J., Appleton, L. H., Brown, M. A., Evans, D. M. & Wordsworth, B. P., 1 Nov 2014, In: Annals of the Rheumatic Diseases. 73, 11, p. 2054-2058 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
A CCR6 variant strongly associated with rheumatoid arthritis in two populations is not associated with ankylosing spondylitis
Cohen, C. J., Karaderi, Tugce, Pointon, J. J. & Wordsworth, B. P., 1 Sep 2013, In: Rheumatology International. 33, 9, p. 2443-2444 2 p.Research output: Contribution to journal › Letter › Research › peer-review
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
Cortes, A., Hadler, J., Pointon, J. P., Robinson, P. C., Karaderi, T., Leo, P., Cremin, K., Pryce, K., Harris, J., Lee, S., Joo, K. B., Shim, S. C., Weisman, M., Ward, M., Zhou, X., Garchon, H. J., Chiocchia, G., Nossent, J., Lie, B. A., Førre, Ø. & 30 others, , 1 Jul 2013, In: Nature Genetics. 45, 7, p. 730-738 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Evidence of genetic association between TNFRSF1A encoding the p55 tumour necrosis factor receptor, and ankylosing spondylitis in UK Caucasians
Karaderi, Tugce, Pointon, J. J., Wordsworth, T. W. H., Harvey, D., Appleton, L. H., Cohen, C. J., Farrar, C., Harin, A., Brown, M. A. & Wordsworth, B. P., 17 Jul 2012, In: Clinical and Experimental Rheumatology. 30, 1, p. 110-113 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
A common functional variant of endoplasmic reticulum aminopeptidase 2 (ERAP2) that reduces major histocompatibility complex class I expression is not associated with ankylosing spondylitis
Harvey, D., Pointon, J. J., Karaderi, Tugce, Appleton, L. H., Farrar, C. & Paul Wordsworth, B., 1 Sep 2011, In: Rheumatology. 50, 9, p. 1720-1721 2 p., ker199.Research output: Contribution to journal › Letter › Research › peer-review
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
Evans, D. M., Spencer, C. C. A., Pointon, J. J., Su, Z., Harvey, D., Kochan, G., Opperman, U., Dilthey, A., Pirinen, M., Stone, M. A., Appleton, L., Moutsianis, L., Leslie, S., Wordsworth, T., Kenna, T. J., Karaderi, T., Thomas, G. P., Ward, M. M., Weisman, M. H., Farrar, C. & 30 others, , 1 Aug 2011, In: Nature Genetics. 43, 8, p. 761-767 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
The histone demethylase JARID1A is associated with susceptibility to ankylosing spondylitis
Pointon, J. J., Harvey, D., Karaderi, Tugce, Appleton, L. H., Farrar, C. & Wordsworth, B. P., 1 Jul 2011, In: Genes and Immunity. 12, 5, p. 395-398 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Erratum: Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene (Genes and Immunity (2010) 11 (490-496) DOI:10.1038/gene.2010.17)
Pointon, J. J., Harvey, D., Karaderi, Tugce, Appleton, L. H., Farrar, C., Stone, M. A., Sturrock, R. D., Brown, M. A. & Wordsworth, B. P., Jun 2011, In: Genes and Immunity. 12, 4, p. 319-320 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2010
The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD)
Pointon, J. J., Harvey, D., Karaderi, Tugce, Appleton, L. H., Farrar, C., Stone, M. A., Sturrock, R. D., Reveille, J. D., Weisman, M. H., Ward, M. M., Brown, M. A. & Wordsworth, B. P., 1 Jun 2010, In: Annals of the Rheumatic Diseases. 69, 6, p. 1243-1246 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
Reveille, J. D., Sims, A. M., Danoy, P., Evans, D. M., Leo, P., Pointon, J. J., Jin, R., Zhou, X., Bradbury, L. A., Appleton, L. H., Davis, J. C., Diekman, L., Doan, T., Dowling, A., Duan, R., Duncan, E. L., Farrar, C., Hadler, J., Harvey, D., Karaderi, T. & 19 others, , 1 Feb 2010, In: Nature Genetics. 42, 2, p. 123-127 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene
Pointon, J. J., Harvey, D., Karaderi, Tugce, Appleton, L. H., Farrar, C., Stone, M. A., Sturrock, R. D., Brown, M. A. & Wordsworth, B. P., 1 Jan 2010, In: Genes and Immunity. 11, 6, p. 490-496 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
Investigating the genetic association between ERAP1 and ankylosing spondylitis
Harvey, D., Pointon, J. J., Evans, D. M., Karaderi, Tugce, Farrar, C., Appleton, L. H., Sturrock, R. D., Stone, M. A., Oppermann, U., Brown, M. A. & Wordsworth, B. P., 20 Oct 2009, In: Human Molecular Genetics. 18, 21, p. 4204-4212 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-analysis of published series
Karaderi, Tugce, Harvey, D., Farrar, C., Appleton, L. H., Stone, M. A., Sturrock, R. D., Brown, M. A., Wordsworth, P. & Pointon, J. J., 2 Apr 2009, In: Rheumatology. 48, 4, p. 386-389 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 225744929
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127
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Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
68
downloads
Cyprus Women's Health Research (COHERE) initiative: determining the relative burden of women's health conditions and related co-morbidities in an Eastern Mediterranean population
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
46
downloads
Host Genetics at the Intersection of Autoimmunity and COVID-19: A Potential Key for Heterogeneous COVID-19 Severity
Research output: Contribution to journal › Journal article › Research › peer-review
Published