Tail Structure and Dynamics
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Tail Structure and Dynamics. / Bhatt, Shweta; Leiman, Petr G.; Taylor, Nicholas M.I.
Reference Module in Life Sciences. Elsevier, 2019.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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TY - CHAP
T1 - Tail Structure and Dynamics
AU - Bhatt, Shweta
AU - Leiman, Petr G.
AU - Taylor, Nicholas M.I.
PY - 2019
Y1 - 2019
N2 - Most viruses of bacteria, or bacteriophages, use a tail structure for the controlled injection of their genome and internal proteins into the bacterial host. The tail, together with proteins located in the capsid of the phage, translocates DNA and proteins from the capsid into the cytoplasm of the host cell while crossing the wall and cell membrane in gram-positive bacteria or two cell membranes and the peptidoglycan layer in gram-negative bacteria. Yet another function of the tail is to coordinate host recognition, which is performed by tail fiber and tailspike proteins emanating from the tail, with irreversible attachment to the host’s surface.
AB - Most viruses of bacteria, or bacteriophages, use a tail structure for the controlled injection of their genome and internal proteins into the bacterial host. The tail, together with proteins located in the capsid of the phage, translocates DNA and proteins from the capsid into the cytoplasm of the host cell while crossing the wall and cell membrane in gram-positive bacteria or two cell membranes and the peptidoglycan layer in gram-negative bacteria. Yet another function of the tail is to coordinate host recognition, which is performed by tail fiber and tailspike proteins emanating from the tail, with irreversible attachment to the host’s surface.
KW - (φ)29
KW - Bacterial virus
KW - Bacteriophage
KW - Contractile injection system
KW - Symmetry
KW - T4
KW - T7
U2 - 10.1016/B978-0-12-809633-8.20965-5
DO - 10.1016/B978-0-12-809633-8.20965-5
M3 - Book chapter
SN - 978-0-12-809633-8
BT - Reference Module in Life Sciences
PB - Elsevier
ER -
ID: 233655466