Quantitative phylogenetic assessment of microbial communities in diverse environments
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Quantitative phylogenetic assessment of microbial communities in diverse environments. / von Mering, C; Hugenholtz, P; Raes, J; Tringe, S G; Doerks, T; Jensen, L J; Ward, N; Bork, P.
In: Science (New York, N.Y.), Vol. 315, No. 5815, 2007, p. 1126-30.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Quantitative phylogenetic assessment of microbial communities in diverse environments
AU - von Mering, C
AU - Hugenholtz, P
AU - Raes, J
AU - Tringe, S G
AU - Doerks, T
AU - Jensen, L J
AU - Ward, N
AU - Bork, P
PY - 2007
Y1 - 2007
N2 - The taxonomic composition of environmental communities is an important indicator of their ecology and function. We used a set of protein-coding marker genes, extracted from large-scale environmental shotgun sequencing data, to provide a more direct, quantitative, and accurate picture of community composition than that provided by traditional ribosomal RNA-based approaches depending on the polymerase chain reaction. Mapping marker genes from four diverse environmental data sets onto a reference species phylogeny shows that certain communities evolve faster than others. The method also enables determination of preferred habitats for entire microbial clades and provides evidence that such habitat preferences are often remarkably stable over time.
AB - The taxonomic composition of environmental communities is an important indicator of their ecology and function. We used a set of protein-coding marker genes, extracted from large-scale environmental shotgun sequencing data, to provide a more direct, quantitative, and accurate picture of community composition than that provided by traditional ribosomal RNA-based approaches depending on the polymerase chain reaction. Mapping marker genes from four diverse environmental data sets onto a reference species phylogeny shows that certain communities evolve faster than others. The method also enables determination of preferred habitats for entire microbial clades and provides evidence that such habitat preferences are often remarkably stable over time.
U2 - 10.1126/science.1133420
DO - 10.1126/science.1133420
M3 - Journal article
C2 - 17272687
VL - 315
SP - 1126
EP - 1130
JO - Science
JF - Science
SN - 0036-8075
IS - 5815
ER -
ID: 40749096