Many putative endocrine disruptors inhibit prostaglandin synthesis

Research output: Contribution to journalJournal articleResearchpeer-review

Prostaglandins (PGs) play key roles in development and maintenance of homeostasis of the adult body. Despite these important roles, it remains unclear whether the PG pathway is a target for endocrine disruption. However, several known endocrine-disrupting compounds (EDCs) share a high degree of structural similarity with mild analgesics.
Original languageEnglish
JournalEnvironmental Health Perspectives
Issue number4
Pages (from-to)534-41
Number of pages8
Publication statusPublished - 1 Apr 2011

    Research areas

  • Animals, Cyclooxygenase 2, Dose-Response Relationship, Drug, Endocrine Disruptors, Fatty Acid Synthesis Inhibitors, Humans, Male, Mast Cells, Mice, Prostaglandins, Rats, Testis

ID: 33744613