Gangliocytic paraganglioma of duodenum metastatic to lymph nodes and liver and extending into the retropancreatic space
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Gangliocytic paraganglioma of duodenum metastatic to lymph nodes and liver and extending into the retropancreatic space. / Amin, S M; Albrechtsen, N Wewer; Forster, J; Damjanov, I; Albrechtsen, Nicolai Jacob Wewer.
In: Pathologica, Vol. 105, No. 3, 06.2013, p. 90-3.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - Gangliocytic paraganglioma of duodenum metastatic to lymph nodes and liver and extending into the retropancreatic space
AU - Amin, S M
AU - Albrechtsen, N Wewer
AU - Forster, J
AU - Damjanov, I
AU - Albrechtsen, Nicolai Jacob Wewer
PY - 2013/6
Y1 - 2013/6
N2 - Gangliocytic paraganglioma (GP) is a rare benign neuroendocrine tumour found most often in the duodenum. To our knowledge, only a dozen cases of possibly malignant duodenal GP with local lymph node metastasis and only one case with liver metastasis have previously been published. Herein, we report an unusual case of GP of the duodenum spreading to the retropancreatic space and metastatic to the liver and lymph nodes. Additionally, the present tumour secreted pancreatic polypeptide (PP) which was detected in the serum during the follow-up period. We suggest that serum PP could be a valuable marker in the diagnosis and follow-up of patients with GP.
AB - Gangliocytic paraganglioma (GP) is a rare benign neuroendocrine tumour found most often in the duodenum. To our knowledge, only a dozen cases of possibly malignant duodenal GP with local lymph node metastasis and only one case with liver metastasis have previously been published. Herein, we report an unusual case of GP of the duodenum spreading to the retropancreatic space and metastatic to the liver and lymph nodes. Additionally, the present tumour secreted pancreatic polypeptide (PP) which was detected in the serum during the follow-up period. We suggest that serum PP could be a valuable marker in the diagnosis and follow-up of patients with GP.
KW - Biopsy
KW - Duodenal Neoplasms
KW - Humans
KW - Liver Neoplasms
KW - Lymphatic Metastasis
KW - Male
KW - Middle Aged
KW - Paraganglioma
KW - Retroperitoneal Space
M3 - Journal article
C2 - 24047035
VL - 105
SP - 90
EP - 93
JO - Pathologica
JF - Pathologica
SN - 0031-2983
IS - 3
ER -
ID: 99613630